At Patents you can conduct a Patent Search, File a Patent Application, find a Patent Attorney, or search available technology through our Patent Exchange. Patents are available using simple keyword or date criteria. If you are looking to hire a patent attorney, you've come to the right place. Protect your idea and hire a patent lawyer.
Pyridonaphthyridine type dual PI3K and mTOR inhibitor and its preparation
The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its...
The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to processes for...
Compounds and formulations suitable for radical scavenging
The present invention relates to compositions and methods of using free radical scavengers with reduced .sup.1O.sub.2 generation. In certain embodiments, these...
Substituted oxopyridine derivatives and use thereof as factor xia/plasma
The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the...
Inhibitor compounds of phosphodiesterase type 10A
The present invention relates to compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof: ...
2-(1H-indazol-3-yl)-1H-imidazo[4,5-C]pyridine and therapeutic uses thereof
Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole...
Complement factor B inhibitors and uses there of
The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as...
The invention provides a method of activating PPAR .gamma. and a method of treating or preventing a disease associated with PPAR .gamma. by administering a...
Heterobifunctional linkers with polyethylene glycol segments and immune
response modifier conjugates made therefrom
Conjugates of an immune response modifier, a linker, and an antigen are disclosed. The linker is represented by formula (I): wherein A is CH or N, p is in a...
Sweet flavor modifier
The present invention includes compounds having structural formula (Ia): ##STR00001## or salts or solvates thereof. These compounds are useful as sweet...
Inhibitors of viral replication, their process of preparation and their
Inhibitors of viral replication of formula (I), their process of preparation and their therapeutical uses. The present invention relates to compounds, their use...
Compounds as tyrosine kinase modulators
The present invention is directed to novel compounds of Formula I. The compounds of the present invention are potent tyrosine kinase modulators, and are...
Compounds of formula (I) are inhibitors of fatty acid amide hydrolase, (FAAH), and which are useful in the treatment of diseases or medical conditions which...
Synthesis of Raltegravir
The present invention relates to a novel synthetic route for the preparation of raltegravir and pharmaceutically acceptable salts, starting from...
Azetidine estrogen receptor modulators and uses thereof
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds...
Phenyl triazole derivative and its use for modulating the GABA.sub.A
This invention relates to a novel phenyl triazole derivative, pharmaceutical compositions containing this compound, and methods of treatment therewith. The...
1-pyrazolyl-3-((4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas
as p38 MAP kinase inhibitors
There are provided compounds of formula (I) which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes, and to their use in therapy,...
Sulfonyl piperidine derivatives and their use for treating prokineticin
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof: (I) in which m, n, W, X, Y, Z, R.sup.1, R.sup.2, R.sup.3...
Process for the preparation of polymorphs of imidacloprid
A process for the preparation of a Form I crystalline polymorph of imidacloprid, including: (i) dissolving imidacloprid in an appropriate amount of aqueous...
Conjugates and associated methods of producing them for the prevention or
treatment of nicotine addiction
The present invention relates in part to chemical compounds, and methods for producing these compounds. The compounds may also be incorporated into compositions...
Materials for organic electroluminescence devices
The present invention describes indenofluorene derivatives of the general formula I, II, III or IV having emitting and hole-transporting properties, in...
Compositions and methods for treating estrogen-related medical disorders
Disclosed herein are methods for treatment of estrogen-related medical disorders. The methods of treatment may comprise administering to a subject in need of...
Method for preparing refined lactide from recovered polylactic acid
A method for preparing lactide from recovered polylactic acid, the method including the following steps: A. pretreating the recovered polylactic acid; B....
Use of polyenylpyrrole derivatives for treating inflammation
The preset invention relates to a method for treating inflammation comprising administering a subject in need thereof with a therapeutically effective amount of...
The invention is directed to a compound of formula I, a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing a compound of formula...
Process for the production of furan derivatives
A process for the production of furan derivatives from carbohydrates in the presence of an acidic catalyst, characterized in that N-methylpyrrolidone is used as...
Method for synthesising 2,5-di(hydroxymethyl)furan and
2,5-di(hydroxymethyl)tetrahydrofuran by selective...
A method for selective hydrogenation of furan-2,5-dialdehyde (DFF) into 2,5-di(hydroxymethyl)furan (DHMF) and into 2,5-di(hydroxymethyl)tetrahydrofuran...
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and
In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): ##STR00001## and include...
4,6-diarylaminothiazines as BACE1 inhibitors and their use for the
reduction of beta-amyloid production
Compounds of formula (I), including pharmaceutically acceptable salts thereof, are set forth herein: wherein R.sup.1 and R.sup.2 are independently hydrogen, or...
The invention provides compounds of formula (I): ##STR00001## wherein R.sup.1-R.sup.7 and W have any of the values defined in the specification, and salts...
Guanidine compounds, and use thereof as binding partners for 5-HT5
The present invention relates to guanidine compounds of the general formula I ##STR00001## corresponding enantiomeric, diastereomeric and/or tautomeric forms...
Fumarate analogs and uses thereof
Aspects of the present disclosure include compounds that find use for the treatment of a variety of autoimmune and inflammatory diseases and disorders....
Process for the synthesis of cyclic alkylene ureas
The invention relates to a process for the synthesis of cyclic alkylene ureas comprising reacting in the presence of a basic catalyst, a difunctional amine A...
Substituted bicyclic dihydropyrimidinones and their use as inhibitors of
neutrophil elastase activity
Substituted bicyclic dihydropyrimidinones of formula 1 ##STR00001## which are inhibitors of neutrophil elastase and useful as medicaments for the treatment of,...
Sulfate of 5-hydroxy-1H-imidazole-4-carboxamide
Sulfate of 5-hydroxy-1H-imidazole-4-carboxamide has such characteristics as suppressed blue coloring, high purity, low hygroscopic property, and superior...
Thermally robust, highly porous, and partially fluorinated organic
framework with affinity for hydrocarbons,...
Porous partially fluorinated materials which bind aliphatic and aromatic hydrocarbons, fluorocarbons and freons with high weight adsorption capacities are...
PRMT1 inhibitors and uses thereof
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein...
Benzazepine dicarboxamide compounds
This invention relates to novel benzazepine dicarboxamide compounds of the formula ##STR00001## wherein R.sup.1 to R.sup.4 are as defined in the description...
Alpha-hydrogen substituted nitroxyls and derivatives thereof as catalysts
Novel alpha-hydrogen substituted nitroxyl compounds and their corresponding oxidized (oxoammonium cations) and reduced (hydroxylamine) forms, and the use of...
NK3 receptor antagonist compound (NK3RA) for use in a method for the
treatment of polycystic ovary syndrome (PCOS)
A method for treating polycystic ovarian syndrome and related conditions with a compound (I): or a pharmaceutically acceptable salt thereof. ##STR00001##
Methods for the preparation of indacaterol and pharmaceutically acceptable
The invention relates to new and improved processes for the preparation of Indacaterol and pharmaceutically acceptable salts thereof as well as intermediates...
Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids
4,6-Dibromo-3-hydroxypicolinonitrile may be prepared from furfural in a series of chemical steps selected from cyano-amination, amine salt formation and...
Low-temperature synthesis of methylphenidate hydrochloride
The present invention describes a process for the preparation of methylphenidate hydrochloride. The process involves the esterification of ritalinic acid and...
Zinc halide mediated cyclization process leading to tricyclic indoles
The present invention relates to a method for the production of tricyclic indole compounds comprising a cyclization step wherein this step is improved over...
Luminogen compounds and the use of the same for biosensing and cellular
Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for...
Polyurethane (meth) acrylates using modified hydroxythiols
The invention provides intermediates of the formula: ##STR00001## as well as a method of their preparation by reacting a thiol having at least two hydroxyl...
Substituted aromatic sulfur compounds and methods of their use
Compounds of formula II are described: ##STR00001## wherein D, n, R.sub.a, R.sub.b, and R.sub.c are as herein defined, along with pharmaceutical compositions...
Polymorphs of N- (2 -methoxybenzoyl) -4- [ (methylaminocarbonyl) amino]
The present invention relates to solid forms of herbicide safeners, to processes for their preparation, compositions comprising the solid forms and methods of...
Synthesis of tetrabutylammonium bis(fluorosulfonyl)imide and related salts
The present invention is directed to methods comprising adding ammonia, either as an ammonium salt or as a gas at pressures below 0.01 MPa, to a sulfuryl...
Photoresist comprising nitrogen-containing compound
New nitrogen-containing compounds are provided that comprise multiple hydroxyl moieties and photoresist compositions that comprise such nitrogen-containing...