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Patent # Description
US-9,480,710 Compositions and methods for treatment of osteoporosis and other indications
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of osteoporosis or other conditions. In some...
US-9,480,709 Methods and compositions for muscular and neuromuscular diseases
The present invention generally relates to compositions and methods for treatment of subjects in need of muscle growth or repair. In some cases, the composition...
US-9,480,708 Treatment and prevention of learning and memory disorders
The present invention generally relates to compositions and methods for transdermal drug delivery, including treatment and prevention of learning and memory...
US-9,480,707 Methods and systems for treatment of inflammatory diseases with nitric oxide
The present invention generally relates to compositions and methods for treatment of various inflammatory diseases, such as inflammatory dermatoses and other...
US-9,480,706 Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of acne or other conditions. In some cases, the...
US-9,480,705 Treatment of skin and soft tissue infection with nitric oxide
The present invention generally relates to compositions and methods for treatment of skin and/or other soft tissues that are infected with bacteria such as...
US-9,480,704 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation
The present disclosure consists of therapeutically-active compositions that combine strontium with at least one additional molecules that increase the overall...
US-9,480,703 Method and composition of glycosaminoglycans in sickle cell and vascular disorders
A composition that includes a nanoparticle. The nanoparticle includes a shell which encapsulates sulfated non-anticoagulant heparin (SNACH). The shell includes...
US-9,480,702 Use of chemically modified heparin derivates in sickle cell disease
The present invention relates to chemically modified heparin for use in the treatment of sickle cell disease, with an antifactor II activity of less than 10...
US-9,480,701 Low anticoagulant heparins
The present invention relates to a chemically modified heparin, with an antifactor II activity of less than 10 IU/mg, an antifactor Xa activity of less than 10...
US-9,480,700 Therapy-enhancing glucan
This invention provides a composition comprising an effective amount of glucan capable of enhancing efficacy of antibodies. This invention further provides the...
US-9,480,699 Compositions and methods for the diagnosis and therapy of BCL2-associated cancers
Provided are methods and compositions for the treatment of cancers associated with overexpression of a BCL2 gene and/or gene product in a subject, and methods...
US-9,480,698 Oligonucleotide analogues incorporating 5-aza-cytosine therein
Oligonucleotide analogs are provided that incorporate 5-aza-cytosine in the oligonucleotide sequence, e.g., in the form of 5-aza-2'-deoxycytidine (decitabine)...
US-9,480,697 Edible energy composition
The disclosure relates to an edible energy composition that includes a methylated xanthine, a choline derivative and a flavorant.
US-9,480,696 Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria
Provided herein are compositions and methods to improve treatment of chronic infections, and reduce, delay, or inhibit formation of biofilms, using specific...
US-9,480,695 Methods for inducing orexin neurons and agent for treating narcolepsy or eating disorder
The invention provides a method for producing an orexin neuron by culturing a pluripotent stem cell or a neural progenitor cell in the presence of...
US-9,480,694 Thiopyrimidinecarboxamide for use in treating pulmonary disease
There is disclosed is a method of treating a pulmonary disease using a pyrimidinecarboxamide compound, and a pharmaceutical composition suitable for inhalation...
US-9,480,693 Substituted bisphenyl butanoic phosphonic acid derivatives as NEP inhibitors
The present invention provides a compound of formula I; ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2 and R.sup.3 are...
US-9,480,692 Sulfated-oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and...
Methods and compositions for the prevention and treatment of liver damage or disease in a subject in need thereof are provided. The methods involve providing...
US-9,480,691 Topical liquid containing refined peanut oil for treating skin proliferation or inflammation disorders
A liquid medicament for use on skin, epithelium, epidermis, body surface and so on containing a refined peanut oil and, for example, at least one agent which...
US-9,480,690 High-strength testosterone undecanoate compositions
The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The...
US-9,480,689 Pheromone composition to stimulate reproduction in female suids and methods of use
The present disclosure provides for compositions and methods of stimulating reproductive behavior and reproductive success and productivity in a suid, such as...
US-9,480,688 Pheromone compositions and their use to modify behavior in different vertebrate species
A composition comprising Androstenone is described for the modification of undesirable or harmful stress-related behaviors or other behaviors or physiology in a...
US-9,480,687 Pyrazine derivatives and uses thereof in renal monitoring
The present invention relates to pyrazine derivatives such as those represented by Formulas I and II below. ##STR00001## X.sup.1 to X.sup.4 of the compounds...
US-9,480,686 Piperazine-substituted benzothiophenes for treatment of mental disorders
The present invention provides a heterocyclic compound represented by the general formula (1): The compound of the present invention has a wide treatment...
US-9,480,685 Abuse-resistant controlled-release opioid dosage form
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress...
US-9,480,684 Orvinol and thevinol derivatives useful in the treatment of anxiety or a compulsive disorder
The invention provides a method of treating anxiety or a compulsive disorder in a subject comprising administering to the subject a compound having formula 2: ...
US-9,480,683 Method of inhibiting mutant C-kit
The present invention includes a method of reducing or inhibiting the kinase activity of C-KIT mutant tyrosine kinase activity in a cell or a subject, and the...
US-9,480,682 Methods for treatment of Fabry disease
Provided are in vitro and in vivo methods for determining whether a patient with Fabry disease will respond to treatment with a specific pharmacological chaperone.
US-9,480,681 Controlled release formulations of nisoldipine
Controlled release oral dosage formulations containing calcium channel blocker and processes for preparation thereof, are provided for once a day treatment. The...
US-9,480,680 Stable pharmaceutical composition of clopidogrel free base for oral and parenteral delivery
The present disclosure provides ready-to-use, oil/water emulsion compositions with mean droplet size (intensity-average, m) of 100-500 nm, wherein the oil phase...
US-9,480,679 Methods for treating malaria, tuberculosis and MAC diseases
Described herein are formulations and methods for treating diseases caused by infectious pathogens, including mycobacterium avium complex, mycobacterium...
US-9,480,678 Antifungal pharmaceutical composition
Disclosed is an antifungal agent for external use, which is characterized by containing a compound represented by the general formula (1), 50 to 95 mass % of an...
US-9,480,677 Enantiomers of spiro-oxindole compounds and their uses as therapeutic agents
This invention is directed to the (S)-enantiomer of the compound of formula (I): ##STR00001## or a pharmaceutically acceptable solvate or prodrug thereof....
US-9,480,676 Use of PDE4 inhibitors and combinations thereof for the treatment of cystic fibrosis
Methods of treating cystic fibrosis by administering a PDE4 inhibitor in combination with one or more cystic fibrosis transmembrane conductance regulator (CFTR)...
US-9,480,675 Method for increasing muscle growth by blocking sirtuin activity
Systems and methods are described providing therapeutic preparations of sirtuin inhibitors, such as SIRT1 inhibitors, for stimulating load-induced skeletal...
US-9,480,674 Method and composition for treating acne
The subject invention provides a method of treating acne in a subject which comprises topically and periodically applying to the subject's acne a composition...
US-9,480,673 Composition and method for treating neurodegenerative disease
The present invention provides a method and composition for treating a neurodegenerative disease. In particular, the present invention provides a method and...
US-9,480,672 Internal composition
An object of the present invention is to provide an internal composition capable of exerting various physiological functions such as a brain-function improving...
US-9,480,671 Reduction of risk of obesity
A nutritional composition comprising a significant amount of arachidonic acid (ARA) is described. Such nutritional composition is particularly suitable for...
US-9,480,670 Reduction of risk of obesity
A nutritional composition comprising a significant amount of arachidonic acid (ARA) is described. Such nutritional composition is particularly suitable for...
US-9,480,669 Method of destroying and preventing bacterial and fungal biofilm by amino acid infusion
Disclosed is a method comprising the administration of a 3% amino acid and 3% glycerin solution for the use of prevention and disruption of bacterial biofilms....
US-9,480,668 Blood flow promoting agent
The present invention provides a blood flow promoting agent containing citrulline or a salt thereof and capsaicin or capsaicinoids as active ingredients, which...
US-9,480,667 Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
An NSAID formulation for encapsulation into a soft gel capsule with increased stability, concentration and bioavailability of the NSAID. The preferred NSAIDS...
US-9,480,666 Compositions and methods for inhibiting intimal hyperplasia
Methods are provided for preventing, inhibiting, or treating intimal hyperplasia in a patient who has undergone a coronary bypass procedure that include...
US-9,480,665 Methods of treating pain or fever using pharmaceutically active acetaminophen dimers linked through phenolic...
Provided herein are methods for treating pain such as acute or chronic pain or fever in subject without risking hepatotoxicity. The subject may be at risk of...
US-9,480,664 Compositions and methods for treating cancer
Compositions containing one or more COX inhibitors in combination with one or more antagonists of 20-HETE (20-hydroxyeicosatetraeonic acid), and optionally a...
US-9,480,663 Biguanide compositions and methods of treating metabolic disorders
Provided herein are methods for treating certain conditions, including diabetes, obesity, and other metabolic diseases, disorders or conditions by...
US-9,480,662 Compositions and methods for topical tamoxifen citrate therapy
The present invention provides topical compositions and methods for administering tamoxifen citrate while minimizing the incidence and or severity of adverse...
US-9,480,661 Solid dosage formulations containing weight-loss drugs
An orally disintegrating tablet which can be chewed or disintegrated by contact with saliva and containing weight-loss drugs for weight control in humans,...
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