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Patent # Description
US-9,481,915 Method of screening drugs that promote LOXL1 expression
The present invention discloses a drug screening method, drugs promoting extracellular matrix protein crosslinking and their applications, the said drug...
US-9,481,914 Methods for the diagnosis of bacterial vaginosis
The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples...
US-9,481,913 Sequences and their use for detection and characterization of E. coli O157:H7
This invention relates to a rapid method for detection and characterization of Escherichia coli bacteria serotype O157:H7 based on the presence of nucleic acid...
US-9,481,912 Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
The invention is directed to compositions and methods for isolating, detecting, amplifying, and quantitating pathogen-specific nucleic acids in a biological...
US-9,481,911 Methods for detecting FGFR3/TACC3 fusion genes
[Problem] The present invention aims to elucidate a polynucleotide as a novel responsible gene for cancer and aims to thus provide a method for detecting the...
US-9,481,910 Methods and compositions for the detection of drug resistant BRAF isoforms
The present invention provides methods and compositions for the detection of novel BRAF splice variants that mediate resistance to BRAF and/or pan-RAF...
US-9,481,909 Multiplex compositions and methods for quantification of human nuclear DNA and human male DNA and detection of...
The invention relates to a method for simultaneous quantification of human nuclear DNA and human male DNA in a biological sample while also detecting the...
US-9,481,908 Compositions, devices, systems, and methods for using a nanopore
The invention herein disclosed provides for devices and methods that can detect and control an individual polymer in a mixture is acted upon by another...
US-9,481,907 Methods for multiplexing amplification reactions
A two-step multiplex amplification reaction includes a first step which truncates the standard initial multiplex amplification round to "boost" the sample copy...
US-9,481,906 Automatic light measurement device with a movable mount for coupling with multiple reaction containers
The invention relates to an automatic response/light measurement device and a method therefor, and the purpose is to effectively and quickly perform an optical...
US-9,481,905 Method of using neutrilized DNA (N-DNA) as surface probe for high throughput detection platform
A method of using Neutrilized DNA (N-DNA) as a surface probe for a high throughput detection platform is disclosed. FET and SPRi are used as high throughput...
US-9,481,904 Electrokinetic method for capturing and bioassaying airborne assayable pathogenic agents
Electrokinetic methods are described with the purpose of collecting assayable agents directed by creation of an electrokinetic potential well. Environmental...
US-9,481,903 Systems and methods for detection of cells using engineered transduction particles
Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some...
US-9,481,902 Quantitative control of sialylation and specific mono-sialylation
The present disclosure is directed to the use of certain glycosyltransferase variants having N-terminal truncation deletions. It was found that the combination...
US-9,481,901 Methods for increasing mannose content of recombinant proteins
The present invention relates to methods of upregulating the high mannose glycoform content of a recombinant protein during a mammalian cell culture by...
US-9,481,900 Polypeptides having oxidoreductase activity and their uses
The invention relates to a polypeptide having oxidoreductase activity which comprises the amino acid sequence set out in SEQ ID NO: 3 or an amino acid sequence...
US-9,481,899 Methods and compositions for producing hydrocarbons
Compositions and methods for producing aldehydes, alkanes, and alkenes are described herein. The aldehydes, alkanes, and alkenes can be used in biofuels.
US-9,481,898 Electro-autotrophic synthesis of higher alcohols
The disclosure provides a process that converts CO.sub.2 to higher alcohols (e.g. isobutanol) using electricity as the energy source. This process stores...
US-9,481,897 Hybrid polypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention provides hybrid polypeptides having cellobiohydrolase activity. The present invention also provides polynucleotides encoding the hybrid...
US-9,481,896 Stem cell gene targeting
The invention provides a method for generating a transgenic eukaryotic cell population having a modified human Rosa26 locus, which method includes introducing a...
US-9,481,895 Introduction of modular vector elements during production of a lentivirus
Methods and kits for lentiviral production are provided. By separating certain components of the vector including but not limited to promoter, reporter and...
US-9,481,894 Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
Disclosed are methods and pharmaceutical compositions for inducing pancreatic hormone production.
US-9,481,893 DNA capable of inducing osteoblast-specific expression
The invention provides nucleotide sequences that function as enhancers and induce osteoblast-specific expression, expression vectors comprising such an...
US-9,481,892 Controlled activation of non-LTR retrotransposons in mammals
The invention relates to nucleic acids, vector constructs which allow the controlled activation and inhibition of retrotransposition of non-LTR ...
US-9,481,891 Soybean variety DLL1206
The soybean variety DLL1206 is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and soybean lint as well as to...
US-9,481,890 Modification of plant development and morphology
A method of modifying morphology in a plant comprising introducing into a plant at least one chimaeric gene comprising a promoter sequence operably associated...
US-9,481,889 Gene controlling shell phenotype in palm
Nucleic acid sequences for predicting and controlling shell phenotype in palm.
US-9,481,888 Recombinant bacterium and methods of antigen and nucleic acid delivery
The present invention provides a recombinant bacterium and methods of using the recombinant bacterium to induce an immune response.
US-9,481,887 DNA aptamers for promoting remyelination
Materials and methods related to using multimeric DNA aptamers to treat demyelinating diseases are provided herein.
US-9,481,886 RNA silencing in animals as an antiviral defense
The present invention provides recombinant DNA constructs for inactivation of viral or endogenous genes in a cell, wherein the construct comprises viral...
US-9,481,885 Methods and compositions related to miR-21 and miR-29a, exosome inhibition, and cancer metastasis
The present invention provides materials and methods related to the discovery that tumor secreted miR-21 and miR-29a can function by binding as ligands to...
US-9,481,884 Enabling the use of long dsRNA for gene targeting in mammalian and other selected animal cells
The present invention provides a method of enabling the use of long dsRNA for gene silencing in mammalian cells through bacteria, preferably non-pathogenic or...
US-9,481,883 Arrays and methods of use
Methods are provided for producing a molecular array comprising a plurality of molecules immoblized to a solid substrate at a density which allows individual...
US-9,481,882 Constitution of tool for analyzing biomolecular interaction and analysis method using same
A method for analyzing biomolecular interactions, which method can be carried out without performing affinity selection using an immobilized bait, is provided....
US-9,481,881 Eluent for ion-exchange chromatography, and method of analyzing nucleic acid chains
The present invention provides eluent for ion-exchange chromatography, wherein the eluent allows separation and detection of a target nucleic acid such as a...
US-9,481,880 Methods of genome installation in a recipient host cell
The presently disclosed invention relates to methods of installing a genome isolated from one species (the donor) into suitably prepared cells of a second...
US-9,481,879 Preparation of stabilized catalase enzymes with a surfactant
There is provided a method of producing a stabilized microcrystalline cellulose powder containing catalase enzyme. In the method, cellulose is thoroughly mixed...
US-9,481,878 Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
The present invention concerns methods and compositions for forming immunotoxin complexes having a high efficacy and low systemic toxicity. In preferred...
US-9,481,877 Engineered primate L-methioninase for therapeutic purposes
Methods and compositions relating to the engineering of an improved protein with methionine-.gamma.-lyase enzyme activity are described. For example, in certain...
US-9,481,876 Cathepsin L inhibitors and probes comprising vinyl sulfonate moiety and methods of using same
Human cathepsin L inhibitors and probes containing a vinyl sulfonate ester moiety are described. The inhibitors are highly potent (low nM affinity), selective,...
US-9,481,875 PCSK9 vaccine
The present invention relates to the provision of immunogens comprising an antigenic PCSK9 peptide linked to an immunogenic carrier for the prevention,...
US-9,481,874 Method to improve the stability and broaden the pH range of family G/11 xylanases
The present invention relates to protein engineering, and concerns especially family G/11 xylanases, and genes encoding said enzymes. In specific, the invention...
US-9,481,873 Polypeptides having ferulic acid esterase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having ferulic acid esterase activity and isolated polynucleotides encoding the polypeptides. The...
US-9,481,872 Nucleic acid-free thermostable enzymes and methods of production thereof
The present invention provides thermostable enzymes, such as DNA polymerases and restriction endonucleases, that are substantially free from contamination with...
US-9,481,871 Nucleic acid encoding a polpeptide having aminotransferase activity, vectors and host cells comprising the...
A method for inexpensively and efficiently producing an optically active amino compound useful as an intermediate for pharmaceutical preparations, agricultural...
US-9,481,870 Nucleic acid encoding a polypeptide having aminotransferase activity, vectors and host cells comprising the...
A method for efficiently producing an optically active amino compound useful as an intermediate for pharmaceutical preparations, agricultural chemicals, or the...
US-9,481,869 Host cell modification with artificial endosymbionts
The present invention is directed generally to host cells with artificial endosymbionts, wherein the artificial endosymbiont and the host cell communicate with...
US-9,481,868 Engineered renal tissues, arrays thereof, and methods of making the same
Disclosed are renal tissues and arrays thereof that include a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and...
US-9,481,867 Method of rapidly inducing large-scale and high-purity mesenchymal stem cells to transdetermine into...
A method of rapidly inducing large-scale and high-purity mesenchymal stem cells to transdetermine into hematopoietic stem cells is provided with the steps of...
US-9,481,866 Methods of producing T cell populations enriched for stable regulatory T-cells
The present invention provides methods for producing cell populations enriched for stable, regulatory T cells (Tregs). In particular, the invention relates to...
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