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Patent # Description
US-9,486,520 Compositions comprising polyglutamic acid nanoparticles and CD40 agonists
The present invention provides pharmaceutical compositions comprising an immunostimulatory polypeptide and polyglutamic acid (PGA) nanoparticles, formulated in...
US-9,486,519 Use of FLT3 ligand for enhancing immune responses in RNA immunization
The invention relates to supplying vaccine RNA to cells. The invention relates in particular to a common use of vaccine RNA and Flt3 ligand for inducing,...
US-9,486,518 Membrane proximal region of HIV GP41 anchored to the lipid layer of a virus-like particle vaccine
Disclosed herein are isolated immunogens including variant hepatitis B surface antigens (HBsAgs). In an example, a variant HBsAg includes a HBsAg with one or...
US-9,486,517 Viral particle released after infection of mammalian cells by human cytomegalovirus (HCMV) containing a fusion...
The present invention is related to a viral particle released after infection of mammalian cells by human cytomegalovirus (HCMV), wherein a) the particle is...
US-9,486,516 Formulations for non-invasive delivery of active proteins to an animal or human
This invention relates to formulations which contain at least one active peptide intended to be used for prevention or treatment of a condition in an animal or...
US-9,486,515 Immunogenic composition
The present application discloses an immunogenic composition comprising at least 2 different N. meningitidis capsular saccharides, wherein one or more is/are...
US-9,486,514 Bordetella outer-membrane protein antigens and methods of making and using the same
An isolated protein or peptide selected from the group consisting of Bordetella colonization factor A (BcfA) protein and antigenic fragments thereof is...
US-9,486,513 Immunization and/or treatment of parasites and infectious agents by live bacteria
Chimeric proteins are expressed, secreted or released by a bacterium to immunize against or treat a parasite, infectious disease or malignancy. The delivery...
US-9,486,512 In situ antigen-generating cancer vaccine
The invention provides compositions and methods for utilizing scaffolds in cancer vaccines.
US-9,486,511 Using pomegranate extracts for increasing prostate specific antigen doubling time
A method of increasing a prostate specific antigen (PSA) doubling time in treating a patient. A subject with rising serum PSA is selected. A composition is...
US-9,486,510 Method to enhance an immune response of nucleic acid vaccination
A composition comprising liposomes associated with a nucleic acid operatively encoding an antigenic protein and with an assistor protein, wherein the assistor...
US-9,486,509 Compositions and methods for preparing a subject for organ or non-organ implantation
Embodiments of the present invention illustrate methods of preventing transplantation rejection. In certain embodiments, a subject in need of an organ or...
US-9,486,508 Blood substitute composition and method of use
The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in...
US-9,486,507 Pro-coagulant compounds and methods of use thereof
The present invention provides pro-coagulant compounds (e.g., pro-coagulant peptides or peptide derivatives) and methods of using and making those compounds....
US-9,486,506 Glucagon analogues
The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of...
US-9,486,505 Glucagon analogues
The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of...
US-9,486,504 Regulation of food preference using GLP-1 agonists
GLP-1 agonists selectively decrease the amount of food intake, wherein the food has a high glycemic index or wherein the amount of mono- and di-saccharides...
US-9,486,503 Medicinal agent for suppressing malignant tumor metastasis
A medicinal composition for suppressing or preventing the metastasis of a malignant tumor, the composition comprising, as an active ingredient, at least one...
US-9,486,502 Methods of administering interferon gamma to absorb fluid from the subretinal space
Particular aspects of the invention provide methods for decreasing the amount of fluid present in the subretinal space of the eye by administering interferon...
US-9,486,501 Method for increasing or maintaining nail growth using granulocyte-colony stimulating factor
The present invention provides a method for re-growing hair in patients with androgenic alopecia by administering effective consecutive courses of...
US-9,486,500 Osteoimplant and methods for making
An osteoimplant is disclosed and includes a plurality of partially demineralized fibers. Each fiber has an elongated, thin body having a length of about 1...
US-9,486,499 Administration of FGF9 for treatment of anxiety
The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as...
US-9,486,498 Method of treating CD40-mediated diseases
A method for treating a CD40-mediated disease in a subject includes administering to cells expressing CD40 of the subject a therapeutically effective amount of...
US-9,486,497 Treatment of immunocompromised conditions
This invention discloses the use of an E-selectin antagonist in methods and compositions for treating or preventing immunocompromised conditions resulting from...
US-9,486,496 Anti periodontitis-causing microorganism agent and medical or dental materials using the same
A medical or dental material can be prepared by using, as an active ingredient, at least one of a protamine, and derivatives thereof and hydrolysates thereof,...
US-9,486,495 Alpha-and gamma-MSH analogues
The present invention provides peptide analogues of .alpha.-MSH and .gamma.-MSH, comprising the amino acid sequence of human .alpha.-MSH or .gamma.-MSH, or...
US-9,486,494 Compositions useful for the treatment of gastrointestinal disorders
This invention provides novel peptides and methods to prevent, control, and treat an inflammation, cancer and other disorders, particularly of the...
US-9,486,493 Use of a peptide and an analgesic pharmaceutical agent
Inflammation caused by disease states such as rheumatism, gout, neurodegeneration and tumours result in the increased effectiveness of the opioid peptide...
US-9,486,492 Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions...
US-9,486,491 Collagen peptide composition production method, DPP-4 inhibitor, and antihyperglycemic agent
Provided are methods of producing a novel collagen peptide composition, and a DPP-4 inhibitor and antihyperglycemics that comprise the above-mentioned collagen...
US-9,486,490 Composition for preventing or treating cancer containing extracts of artocarpus altilis fruits, leaves, or...
The present invention relates to a pharmaceutical composition for preventing and treating cancer which comprises the extracts of Artocarpus altilis fruits,...
US-9,486,489 Method for producing dry extracts
The invention relates to a method for producing dry extracts of plants and to pharmaceutical preparations containing the same, more particularly ...
US-9,486,488 Skin-lightening agent
Provided are a very safe skin whitening agent, melanin production inhibitor, and dopa oxidase activity inhibitor. Use of kitsunenomago or an organic solvent...
US-9,486,487 Methods and compositions relating to microbial treatment and diagnosis of disorders
The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease....
US-9,486,486 Bacterium and extracts of said bacterium and the use of same in therapy
The present invention relates to a novel bacterial strain isolated and characterized from groundwater. The invention also relates to bacterial extracts and to...
US-9,486,485 Methods for treating urushiol-induced contact dermatitis
The invention is directed to methods for treating urushiol-induced contact dermatitis. Specifically, the invention is directed to treating and reducing...
US-9,486,484 Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
Aspects of the invention provides methods for preparing and using adipose-tissue-derived stem and progenitor cells, adipose-tissue-derived lymphatic endothelial...
US-9,486,483 Bone grafts including osteogenic stem cells, and methods relating to the same
Bone grafts and constructs including stem cells are provided. Example bone grafts include osteogenic stem cells seeded on a scaffold of osteoconductive...
US-9,486,482 Herbal composition for treating male sexual dysfunction
Disclosed herein is synergistic herbal composition comprising extracts of herbal ingredients of Tribulus terrestris, Withania somnifera, Curculigo orchioides,...
US-9,486,481 Method of modulating fatty acid mobilization and oxidation
Methods of mobilizing fatty acids are disclosed.
US-9,486,480 Surface-modified heavy metal nanoparticles, compositions and uses thereof
Surface-modified heavy metal nanoparticles, including a heavy metal core and a coating layer, the coating layer having at least one ligand, conjugated to...
US-9,486,479 Antimicrobial solutions containing dichloride monoxide and methods of making and using the same
Methods and products are provided for treating a wound or infection in a mammal or disinfecting a surface with a hypochlorous acid solution that has been...
US-9,486,478 Compositions and methods for preferential distribution of active agents to injury sites
Compositions are provided for preferential distribution of active agents to injury sites. Such compositions may comprise a ligand with hydrophilic properties...
US-9,486,477 Nitric oxide generator and non-deliquescent tablet for use in same
An apparatus to generate nitric oxide is disclosed in one embodiment in accordance with the invention as including a heat source and a vessel containing the...
US-9,486,476 Fast acting joint relief formulations
The instant invention provides a method and composition for treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis,...
US-9,486,475 PPS for the prevention of potential adverse effects caused by CD3 specific binding domains
The present invention relates to a pentosanpolysulfate (PPS) or a pharmaceutically acceptable salt thereof for use in the amelioration, treatment, or prevention...
US-9,486,474 Interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis
The present invention relates to a disorder of the lower urinary tract, and in particular, reducing the symptoms (including treatment) of interstitial cystitis...
US-9,486,473 MicroRNAs and uses thereof
The present invention provides novel microRNAs and their uses.
US-9,486,472 Methods for modulating neuronal responses
Methods and compositions for treating neurological damage or dysfunction are described, including methods implemented by administration of peptide inhibitors of...
US-9,486,471 Combination therapy for the treatment of cancer
Described are methods and compositions for treating cancer that include a dopamine receptor (DR) antagonist such as thioridazine and a chemotherapeutic agent....
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