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Patent # Description
US-9,492,578 Reconfigurable surfaces for information security and protection of physical biometrics
Surfaces for information security and protection of physical biometrics, such as a fingerprint, is described. Such biometric information recording surface...
US-9,492,577 Decontamination enclosure and method
Provided are a method and apparatus for decontaminating personal protective equipment while it is being worn by a person. A booth having a plurality of...
US-9,492,576 Display screen with light-emitting diodes for ultraviolet disinfection
An apparatus includes a display screen including a first array of first light-emitting diodes for emitting visible light and a second array of second...
US-9,492,575 Color changing and disinfecting surfaces
An apparatus configured to disinfect a vehicle is disclosed. The apparatus comprises a first electrode substantially coating a portion of a partially light...
US-9,492,574 Apparatus for disinfecting or sterilizing a catheter and method of use
An elliptical-shaped housing contains a UV light source and a power source. A connector is removably mounted in the housing and is disinfected or sterilized by...
US-9,492,573 Method of treating cholangiocarcinoma and apparatus
Biological implants have an electroplated surface wherein a substantial portion of the electroplated surface is covered with dendrites. The dendrites assist in...
US-9,492,572 Dimeric binding proteins based on modified ubiquitins
The present invention refers to novel dimeric proteins obtained from modified ubiquitin capable of binding targets with high affinity. The novel dimeric binding...
US-9,492,571 Molecular probes for multimodality imaging and tracking of stem cells
The invention relates to novel multi-modality probes for imaging, tracking and analyzing stem cells and related biological samples, and methods of preparation...
US-9,492,570 Device and method for safe location and marking of a biopsy cavity
Cavity and sentinel lymph node marking devices, marker delivery devices, and methods are disclosed. More particularly, upon insertion into a body, the cavity...
US-9,492,569 Antibodies that bind integrin alpha-V beta-8
Provided herein are antibodies with high affinity for the .beta.8 subunit of .alpha.v.beta.8.
US-9,492,568 Method for suppressing cell growth
Disclosed is a method for suppressing the growth of a target cell, which is not limited in the type of a target cell and the type of a protein to be expressed...
US-9,492,567 Combined RF/microwave amplifiers with individual power supplies
A high power amplifier may amplify an RF or microwave input signal. The amplifier may include: an input signal divider (DIV) that has an input port for the...
US-9,492,566 Antibody-drug conjugates and uses thereof
The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may...
US-9,492,565 Human antibody drug conjugates against tissue factor
Antibody drug conjugates against tissue factor. Also disclosed are pharmaceutical compositions comprising the antibodies and antibody drug conjugates, and...
US-9,492,564 Dual specific immunotoxin for brain tumor therapy
We tested the in vitro and in vivo efficacy of a recombinant bispecific immunotoxin that recognizes both EGFRwt and tumor-specific EGFRvIII receptors. A single...
US-9,492,563 Antibody/drug conjugates and methods of use
The invention relates to conjugates that bind to targets, methods of using conjugates that bind to targets and methods of treating undesirable or aberrant cell...
US-9,492,562 Targeted human-interferon fusion proteins
This disclosure relates to a modified .alpha.-helical bundle cytokine, with reduced activity via an .alpha.-helical bundle cytokine receptor, wherein the...
US-9,492,561 Dock-and-Lock (DNL) Complexes for delivery of interference RNA
Described herein are compositions and methods of use of targeted delivery complexes for delivery of siRNA to a disease-associated cell, tissue or pathogen. The...
US-9,492,560 Emetine derivatives, prodrugs containing same, and methods of treating conditions using same
Compounds are provided herein which are emetine derivatives that can be used as prodrugs which selectively undergo activation to release emetine in specific...
US-9,492,559 Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and...
US-9,492,558 Combined meningococcal conjugates with common carrier protein
Carrier-induced epitopic suppression is of particular concern where multiple conjugates with the same carrier protein are administered simultaneously. To avoid...
US-9,492,557 Derivatisation of granulocyte colony-stimulating factor
The present invention relates to a compound which is a polysaccharide derivative of GCSF, or of a GCSF like protein, wherein the polysaccharide is anionic and...
US-9,492,556 N-terminal derivatisation of proteins with polysaccharides
The present invention relates to methods for producing N-terminal derivatives of proteins in which a polysaccharide, preferably having at least terminal sialic...
US-9,492,555 Nucleophilic catalysts for oxime linkage
The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein comprising...
US-9,492,554 Methods and compositions related to viral inhibition
Disclosed herein are compounds, compositions and methods related to viral inhibition. In some forms, the compounds, compositions and methods are related to...
US-9,492,553 Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
The present invention relates to antibody-drug conjugate compounds of Formula I: Ab-(L-D).sub.p I where one or more nemorubicin metabolite or analog drug...
US-9,492,552 Injectable aqueous pharmaceutical compositions comprising a cyclodextrin, a hydrophobic drug, a co-solvent, and...
The invention relates to injectable pharmaceutical compositions, methods of use and formulation, wherein the compositions comprise: one or more water soluble...
US-9,492,551 Orally administrable gallium compositions and methods of use
Provided are pharmaceutical gallium compositions that are particularly useful for oral administration. The pharmaceutical compositions include solid, liquid,...
US-9,492,550 Pharmaceutical compositions with enhanced performance and improved processability
The presently disclosed and claimed inventive concept(s) relates to a polymer for enhancing drug performance and improving processability. Specifically, the...
US-9,492,549 Antimicrobial gels
The present invention pertains to antimicrobial compositions comprising inter alia at least one alkenyl- and/or alkynyl-substituted polysiloxane, at least one...
US-9,492,548 Emulsion containing a non-live medicinal substance
The present invention pertains to an emulsion comprising an aqueous phase and an oily phase, the aqueous phase containing a non-live medicinal substance,...
US-9,492,547 Polymorphic form of inulin and uses thereof
The present invention relates to a new polymorphic form of inulin, designated delta inulin (dIN), to methods for the preparation of dIN, compositions comprising...
US-9,492,546 Use of bethanechol for treatment of Xerostomia
A formulation for topical administration, comprises bethanechol and a penetration enhancer. The formulation is preferably used by being maintained in the buccal...
US-9,492,545 Compositions of statins and omega-3 fatty acids
The present disclosure provides pharmaceutical compositions of statins and polyunsaturated fatty acids (PUFAs), in which the statins are dissolved in the PUFAs,...
US-9,492,544 Compositions and methods for targeting nuclear import shuttles and treating inflammatory disorders
The present invention relates to compositions and methods for treating autoimmune, microbial, metabolic, neoplastic, and posttraumatic diseases mediated by...
US-9,492,543 Compositions for treating cognitive disorders
Disclosed herein is a pharmaceutical composition comprising a cholinesterase inhibitor and compound of the following formula: ##STR00001## The composition is...
US-9,492,542 Pharmaceutical composition for the treatment of MCP-1 mediated inflammatory diseases
The present invention relates to a pharmaceutical composition comprising a combination of 1-benzyl-3-hydroxymethylindazole derivative, a pressure lowering agent...
US-9,492,541 Phenylepherine containing dosage form
A pharmaceutical dosage form which comprises phenylepherine or a pharmaceutically acceptable salt thereof and a second drug. The dosage form provides a plasma...
US-9,492,540 Methods for treating cancer using anti-PD-1 antibodies
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity....
US-9,492,539 Monoclonal antibodies to Programmed Death 1 (PD-1)
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity....
US-9,492,538 Isolation and use of solid tumor stem cells
A small percentage of cells within an established tumor have the properties of stem cells. These solid tumor stem cells give rise both to more tumor stem cells...
US-9,492,537 Methods and compositions involving immunostimulatory oligodeoxynucleotides
Described is an immunostimulatory oligodeoxynucleic acid molecule (ODN) having the structure according to formula (I), wherein any NMP is a 2' deoxynucleoside...
US-9,492,536 Compositions and methods using recombinant MHC molecules for the treatment of stroke
Two-domain MHC polypeptides are useful for modulating activities of antigen-specific T-cells, including for modulating pathogenic potential and effects of...
US-9,492,535 Peanut formulations and uses thereof
The present application relates to compositions for oral immunotherapy of peanut allergies. Further, the present application relates to methods for the...
US-9,492,534 Microorganisms for therapy
Therapeutic methods and vaccinia virus therefor are provided. The viruses are designed so that they accumulate in immunoprivileged tissues and cells, such as in...
US-9,492,533 HSV-1 and HSV-2 vaccines and methods of use thereof
This invention provides methods of treating, suppressing, inhibiting, reducing an incidence, reducing the pathogenesis of, ameliorating the symptoms of, or...
US-9,492,532 Nucleic acids encoding mosaic HIV-1 gag proteins
The disclosure generally relates to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a...
US-9,492,531 Recombinant RSV vaccines
This disclosure provides recombinant respiratory syncytial virus (RSV) antigens and methods for making and using them, including immunogenic compositions (e.g.,...
US-9,492,530 H3 influenza a virus
The invention provides an isolated H3 equine influenza A virus, as well as methods of preparing and using the virus, and genes or proteins thereof.
US-9,492,529 Method for priming of T cells
The present invention relates to an in vitro method for priming T cells suitable for administration to a patient having a viral infection. The invention is also...
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