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Patent # Description
US-9,492,478 Encoded bioelectronic method and system and calcium treatment for slaying cancer by rapid triggering of...
A bioelectronic medical method and system for rapidly destroying living cancer cells and the tumors they create including metastatic off-spring of such tumor(s)...
US-9,492,477 Compositions comprising citrate and applications thereof
In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises...
US-9,492,476 Potassium-binding agents for treating hypertension and hyperkalemia
The present invention generally relates to methods of treating hypertension (HTN) in patients in need thereof wherein the patient optionally further suffers...
US-9,492,475 Antioxidant composition
The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a...
US-9,492,474 Compositions of hyaluronan with high elasticity and uses thereof
The present invention provides compositions comprising hyaluronan with high elasticity, as well as methods for improving joint function, reducing pain...
US-9,492,473 Glycan therapeutics and related methods thereof
Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics,...
US-9,492,472 Compositions and methods of treating cancer
A method of inhibiting neoplastic, cancer, and/or tumorgenic cell proliferation, cell growth and motility in a subject includes administering to a cancer cell...
US-9,492,471 Methods of treating a disease or disorder associated with Bruton'S Tyrosine Kinase
The present invention provides methods of treating, stabilizing or lessening the severity or progression of a disease or disorder associated with BTK.
US-9,492,470 Use of HMGA-targeted phosphorothioate DNA aptamers to suppress carcinogenic activity and increase sensitivity...
Elevated high mobility group A (HMGA) protein expression in human cancer cells, and especially human pancreatic cancer cells, is correlated with resistance to...
US-9,492,469 Combination therapy for the treatment of proliferative diseases
A method of treating a proliferative disease, such as cancer, is disclosed. The method comprises administering to a mammal in need thereof synergistically...
US-9,492,468 Methods and compositions for treatment of acute heart failure
The present disclosure provides methods and compositions for treating acute heart failure, by administering to a subject in need thereof a therapeutically...
US-9,492,467 Rapid-acting insulin formulation comprising an oligosaccharide
A composition in aqueous solution, including an insulin and at least one oligosaccharide whose average degree of polymerization is between 3 and 13 and whose...
US-9,492,466 Beta-hydroxy-gamma-aminophosphonates for treating immune disorders
The present disclosure provides methods of treating, ameliorating, or preventing immune disorders, allergic disorders, or inflammatory disorders, or...
US-9,492,465 Gold(I) complexes with t-butyl phosphine and dialkyl dithiocarbamate ligands
Gold(I) complexes of formulae [Au{P(t-Bu).sub.3}(S.sub.2CN(CH.sub.3).sub.2)] (1), and [Au{P(t-Bu).sub.3}(S.sub.2CN(C.sub.2H.sub.5).sub.2)] (2) have been ...
US-9,492,464 Composition for preventing or treating side effect of steroid in subject comprising acetylsalicylic acid and...
A method for preventing or treating side effects of glucocorticoid in a subject including administrating to a subject acetylsalicylic acid a pharmaceutically...
US-9,492,463 Na/K-ATPase ligand and uses thereof in wound healing
Methods and compositions for detecting, treating, characterizing, and diagnosing interstitial lung and/or fibrotic diseases are described.
US-9,492,462 Composition for elastin production
Compositions and methods for inducing the deposition of elastin in skin by administering compositions including a mineralocorticoid, such as, for example,...
US-9,492,461 Methods and compositions for treating intervertebral disc herniations
Methods and compositions are provided for treating an intervertebral disc herniation by local administration of one or more biodegradable drug depots comprising...
US-9,492,460 Carbazole compounds useful as bromodomain inhibitors
The present invention is directed to carbazole compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using...
US-9,492,459 Pharmaceutical composition of linezolid
The present invention relates to a novel pharmaceutical composition of Linezolid. The present invention relates to a novel pharmaceutical composition comprising...
US-9,492,458 Treatment of erectile dysfunction and other indications
The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of...
US-9,492,457 Substituted xanthine derivatives
This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention...
US-9,492,456 Valomaciclovir polymorphs
The present invention relates to crystalline forms of valomaciclovir, processes for preparing crystalline forms of valomaciclovir, pharmaceutical compositions...
US-9,492,455 Methods of treating NFA-1 organism infection using apocynin
Described herein are compounds and pharmaceutical formulations thereof that can be administered to a subject infected with or suspected of being infected with...
US-9,492,454 Use of pemirolast in the treatment of acute asthma
According to the invention there is provided pemirolast, or a pharmaceutically acceptable salt thereof, for use in the therapeutic treatment of asthma, such as...
US-9,492,453 Protein kinase B inhibitors
The invention relates to a novel group of compounds of Formula (I) or salts thereof: ##STR00001## wherein Y, Z.sup.1, Z.sup.2, R.sup.1, R.sup.4, R.sup.5 and n...
US-9,492,452 Methods and compositions for inhibition of polymerase
The present invention is directed to methods and compositions for inhibition of viral nucleic acid polymerases, such as RNA and DNA polymerases, and methods and...
US-9,492,451 Stable compositions of tetrahydrobiopterin
The present invention relates to stable pharmaceutical compositions of tetrahydrobiopterin and processes for producing such compositions. Particularly the...
US-9,492,450 Inhibition of dynamin related protein 1 to promote cell death
The present invention relates to compositions and methods for reducing cell proliferation and/or promoting cell death by inhibiting Drp1. It is based, at least...
US-9,492,449 Therapies for hematologic malignancies
The invention provides methods that relate to a novel therapeutic strategy for the treatment of hematological malignancies and inflammatory diseases. In...
US-9,492,448 Compositions and methods for regulating glucose homeostasis and insulin action
The present invention encompasses the use of compounds for a novel approach to treat and prevent diseases, conditions, and disorders such as diabetes and...
US-9,492,447 Cannabinoid receptor modulators
Provided are certain methods useful in the treatment of pain comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that...
US-9,492,446 Manufacturing method of solid dispersion containing itraconazole
The present invention relates to a method for preparing an itraconazole-containing solid dispersion. The itraconazole-containing solid dispersion according to...
US-9,492,445 Peripheral opioid receptor antagonists and uses thereof
The present invention provides a compound of formula I: ##STR00001## wherein X.sup.-, R.sup.1, and R.sup.2 are as defined herein, and compositions thereof.
US-9,492,444 Extruded extended release abuse deterrent pill
The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse...
US-9,492,443 Abuse deterrent compositions and methods of making same
This invention relates a therapeutic pharmaceutical composition comprising: a mixture including an opioid; polyethylene oxide in an amount of about 3 to about...
US-9,492,442 Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan
Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional...
US-9,492,441 Drug treatment of overactive bladder
Provided are methods of treating an overactive bladder in a patient which include: administering a Myosin II ATPase inhibitor compound; or administering an X...
US-9,492,440 Bicyclic amides for enhancing glutamatergic synaptic responses
This invention relates to bicyclic amide compounds, pharmaceutical compositions and methods for use in the prevention and treatment of a variety of conditions...
US-9,492,439 Amido compounds as ROR.gamma.t modulators and uses thereof
Amido compounds are disclosed that have a formula represented by the following: ##STR00001## and wherein n1, n2, R.sup.1a, R.sup.1b, R.sup.2, R.sup.3,...
US-9,492,438 Amphiphilic pyridinum compounds to treat epilepsy and other disorders of the nervous system
A pharmaceutical composition including an amphiphilic pyridinium compound for treating neurological disorders or seizure disorders, in particular epilepsy, and...
US-9,492,437 Otamixaban for treatment of elderly and renal impaired non-ST elevation myocardial infarction patients
The invention relates to the use of (2R,3R)-2-(3-carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl)benzoylamino]- -butyric acid methyl ester or a pharmaceutically...
US-9,492,436 Azabenzimidazole derivatives
The present invention relates to compounds of general formula I, ##STR00001## wherein the group R.sup.1, R.sup.2, X and Y are defined as in claim 1, which have...
US-9,492,435 Cyclopamine analogs
The invention provides derivatives of cyclopamine having the following formula: ##STR00001##
US-9,492,434 Combination compositions and methods of treatment
The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as methods of modulating cellular...
US-9,492,433 Pharmaceutical composition for the treatment of Duchenne muscular dystrophy
This invention relates to pharmaceutical compositions comprising 5-(ethylsulfonyl)-2-(naphthalen-2-yl)benzo[d]oxazole (C1100), to processes for preparing the...
US-9,492,432 Methods and compositions for preserving photoreceptor and retinal pigment epithelial cells
Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular...
US-9,492,431 Therapeutic agent for keratoconjunctive disorders
The present invention addresses the problem of providing a novel therapeutic agent for keratoconjunctive disorders. As a means for solving the problem, a...
US-9,492,430 Methods and compositions associated with the granulocyte colony-stimulating factor receptor
Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor...
US-9,492,429 Method of dosing and use of soft anticholinergic esters
A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about...
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