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Patent # Description
US-9,492,428 Compounds, compositions, pharmaceutical compositions, and methods of use
Certain embodiments of the invention include compositions comprising a compound of Formula (I), and salts, isomers, and derivatives thereof. Pharmaceutical...
US-9,492,427 CDC7 kinase inhibitors and uses thereof
The invention provides compounds, methods, pharmaceutical compositions, and kits for the treatment of proliferative disorders such as cancer. In one aspect, the...
US-9,492,426 Mycophenolic acid analogues as anti-tumor chemosensitizing agents
In some embodiments, the present invention provides methods of treating a tumor in a subject. In some embodiments, the methods may include a step of...
US-9,492,425 Crystalline forms of genistein
The disclosure relates to new crystalline forms of genistein. The disclosed crystalline forms include crystalline genistein sodium salt dihydrate; crystalline...
US-9,492,424 Muscle atrophy inhibitor
An extract of Citrus depressa, preferably an organic solvent extract of a fruit and/or leaf of Citrus depressa, a supercritical extract of a fruit and/or leaf...
US-9,492,423 Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof
Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include bendamustine, or a pharmaceutically acceptable...
US-9,492,422 Therapeutic or prophylactic agent for diabetes
A therapeutic or prophylactic agent for diabetes includes a thiazolidine derivative as a PPAR-.gamma. agonist as an effective component which exhibits a reduced...
US-9,492,421 Nutritional supplements for treatment of iron deficiency anemia
The present invention relates to nutritional supplements to be administered to, or to be taken by, people who are subject, or thought to be subject to, iron...
US-9,492,420 3-methanesulfonylpropionitrile for treating inflammation and pain
The present invention relates to purified 3-methanesulfonylpropionitrile or a pharmaceutically acceptable salt thereof, and a method for preparing such...
US-9,492,419 Method for treating crohn'S disease or ulcerative colitis by administering a compound which binds...
The present invention relates to the field of therapeutic methods, compositions and uses thereof, that affect, directly or indirectly, the behavior of LRP...
US-9,492,418 Inhibitors of PFKFB3 for cancer therapy
Compounds used to inhibit glycolytic pathway small molecule kinase 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB) are set forth; these inhibitors...
US-9,492,417 Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer
The present disclosure relates to the discovery that compounds of the invention, particularly 3-bromopyruvate and related compounds, can be safely administered...
US-9,492,416 Use of caftaric acid and lactic bacterium in food supplement for regulating skin pigmentation
The present invention relates generally to the field of cosmetic and/or food supplement. More specifically, the present invention aims to provide the use of at...
US-9,492,415 Methods of treating Parkinson's disease using viral vectors
Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection...
US-9,492,414 Treatment and diagnosis of colon cancer
The present invention discloses novel agents and methods for diagnosis and treatment of colon cancer. Also disclosed are related arrays, kits, and screening...
US-9,492,413 Use of salt of an acetylsalicylic acid for the treatment of viral infections
The invention relates to a method of use of a composition comprising a salt of the o-acetylsalicylic acid with a basic amino acid for producing a pharmaceutical...
US-9,492,412 Penetrating pharmaceutical foam
The invention relates to an alcohol-free cosmetic or pharmaceutical foam composition comprising water, a hydrophobic solvent, a surface-active agent, a gelling...
US-9,492,411 Medications for deposition on biological surfaces
Personal care compositions, such as oral medication compositions containing a flavor system comprising one or more coolants. The pleasant cool sensation...
US-9,492,410 Methods for treatment of Parkinson's disease
New uses of safinamide, safinamide derivatives and MAO-B inhibitors in novel types of treatment for Parkinson's Disease are described. More specifically, the...
US-9,492,409 Compositions and methods for the treatment of local pain
The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and...
US-9,492,408 Protection from chemical-induced acute lung injury
Methods are provided herein for treating an individual having a disease, disorder or condition affecting the lungs, wherein said disease, disorder, or condition...
US-9,492,407 Topical formulation for treatment of hyperkeratotic skin
The present invention relates in general to topical compositions having improved antimicrobial effect useful for the treatment of hyperkeratotic skin...
US-9,492,406 Pharmaceutical composition
The present invention relates to a novel pharmaceutical composition having enhanced bioavailability through improved aqueous dissolution of poorly water soluble...
US-9,492,405 Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas
This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogs for the treatment of a tumor expressing a ...
US-9,492,404 Compositions and methods for treatment of taupathy
Provided are electrokinetically-altered fluids (e.g., electrokinetically-altered gas-enriched fluids and solutions) comprising an ionic aqueous solution of...
US-9,492,403 Method of treating overactive bladder, not due to cancer, by administering at least one jasmonate
A formulation or composition contractility comprising jasmonate for modulating bladder and/or treating bladder dysfunction, particularly an overactive bladder...
US-9,492,402 Formulation of curcuminoids with enhanced bioavailability of curcumin, demethoxycurcumin, bisdemethoxycurcumin...
A formulation of curcuminoid mixture having curcumin, demethoxycurcumin and bisdemethoxycurcumin and an essential oil of turmeric having 45% Ar-turmerone. The...
US-9,492,401 Transdermal systems containing multilayer adhesive matrices to modify drug delivery
A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric...
US-9,492,400 Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
A composition for delivering an active agent to a patient. The composition includes a polymer core encapsulating the active agent and a mucoadhesive coating...
US-9,492,399 Method of treating iron deficiency
A method of treating a condition related to iron deficiency. The method includes steps of identifying a patient having a condition related to iron deficiency...
US-9,492,398 Nanocapsulation of essential oils for preventing or curing infectious diseases alone or with an antibiotic
A composition, an encapsulated composition and/or nanoparticles comprising at least one essential oil having a large spectrum antibacterial, antiparasitic,...
US-9,492,397 Alcohol-resistant sustained-release oral pharmaceutical form based on microgranules
Oral pharmaceutical form containing microgranules for the sustained release of at least one active principle, including a neutral carrier that is insoluble in...
US-9,492,396 Enhanced drug delivery pill
An ingestible pill includes a coating configured to dissolve in a small intestine; a core, which includes a medication-delivery element, which (a) has a...
US-9,492,395 Film coating composition and methods of making and using the same
A film coating composition comprising a cellulosic polymer, an opacifying agent, and a fatty acid is disclosed herein. Also disclosed is a film coating...
US-9,492,394 Gastric resistant pharmaceutical or nutraceutical formulation comprising one or more salts of alginic acid
The invention relates to a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active...
US-9,492,393 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-9,492,392 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-9,492,391 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-9,492,390 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-9,492,389 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-9,492,388 Coated particles for sustained-release pharmaceutical administration
Coated microparticles for sustained-release of an active pharmaceutical ingredient after parenteral administration, and methods of producing such coated...
US-9,492,387 Ternary mixture formulations
The invention relates to a novel free-flowing powder pharmaceutical formulation for the delivery of a poorly-water-soluble drug substance that increases the...
US-9,492,386 Liposomal apparatus and manufacturing methods
The present invention provides apparatus and processes for producing liposomes. By providing a buffer solution in a first reservoir, and a lipid solution in a...
US-9,492,385 Temperature-sensitive liposomal formulation
A liposome contains an active agent and has a gel-phase lipid bilayer membrane comprising phospholipid and a surface active agent. The phospholipids are the...
US-9,492,384 Microemulsion and sub-micron emulsion process and compositions
An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of desonide is provided, along with a method of medical or cosmetic...
US-9,492,383 Rapid in-situ gel forming compositions prepared via reaction of vinyl sulfone derivatized hyaluronic acid with...
The present application provides rapid-gelling, sprayable hyaluronic-acid based compositions, kits, related methods, precursor formulations, and uses thereof.
US-9,492,382 Hyperbranched polyester having a hydrophobic core for solubilizing active ingredients of low solubility
The present invention provides a composition comprising an active ingredient with a maximum solubility in water at 20.degree. C. of 10 g/l, and a hyperbranched...
US-9,492,381 Method of administering hyaluronan formulation for preventing and ameliorating osteoarthritis
Disclosed is a method for mitigating or ameliorating osteoarthritis in vertebrate subjects including administering to a subject a therapeutically effective...
US-9,492,380 Rapidly dispersible dosage form of topiramate
A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The...
US-9,492,379 Quickly soluble oral film dosage containing steviosides as a unpleasant taste masking agent
Disclosed is a quickly soluble oral film dosage for masking a nasty taste, in particular, a quickly soluble oral film dosage comprising a stevioside based...
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