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Patent # Description
US-9,493,784 Pepper plants and fruits with improved nutritional value
The present invention concerns Capsicum annuum plants producing pepper fruits, exhibiting new physicochemical characteristics of the pepper fruit in relation...
US-9,493,783 Hibiscus cannabinus feruloyl-coa:monolignol transferase
The invention relates to isolated nucleic acids encoding a feruloyl-CoA:monolignol transferase and feruloyl-CoA:monolignol transferase enzymes. The isolated...
US-9,493,782 Inducible promoter sequences for regulated expression and methods of use
The plant promoter of a CBSU-Anther_Subtraction library (CAS1) gene encoding a mannitol dehydrogenase, and fragments thereof, and their use in promoting the...
US-9,493,781 Synthetic brassica-derived chloroplast transit peptides
This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some...
US-9,493,780 Chloroplast transit peptide
This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some...
US-9,493,779 FAD2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
Methods and compositions for gene disruption, gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene...
US-9,493,778 Methods and compositions for genetically manipulating clostridia and related bacteria with homologous...
Methods for enhancing single cross-over homologous recombination in gram positive bacteria are presented. These methods provide enhanced capability to...
US-9,493,777 Method for producing an L-amino acid using a bacterium of the family enterobacteriaceae having overexpressed...
The present invention provides a method for producing L-amino acids or salts thereof by fermentation using a bacterium of the family Enterobacteriaceae,...
US-9,493,776 System for increasing gene expression and vector comprising the system
An object of the present invention is to provide a method for increasing the expression of foreign genes, in particular, using a promoter, an enhancer, and the...
US-9,493,775 Inhibition of the glycine cleavage system for treatment of cancer
In some aspects, methods of inhibiting survival or proliferation of a tumor cell are provided, the methods comprising inhibiting the glycine cleavage system...
US-9,493,774 Inhibition of PCSK9 through RNAi
The invention relates to various PCSK9 RNAi constructs with gene silencing activities, and uses thereof. The construct has a double-stranded region of 19-49...
US-9,493,773 Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides
The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated...
US-9,493,772 Method for reducing expression of downregulated in renal cell carcinoma in malignant gliomas
The present invention relates to novel compositions and therapeutic methods for the treatment of cancer, in particular malignant glioma. The compositions...
US-9,493,771 Short interfering ribonucleic acid (siRNA) for oral administration
Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at...
US-9,493,770 Method for identifying antibiotic targets by complemented sequencing
Provided herein are methods, and related compositions for identifying a putative essential gene which serves as an antibiotic target in a bacterium, the method,...
US-9,493,769 Yeast-based assay for measuring the functional activity of an HIV-1 protease in response to an antiviral agent
A method of determining sensitivity or resistance of isolates of HIV retroviruses to a molecule includes a) amplifying sequences coding for a protease of a...
US-9,493,768 Translational enhancer-element dependent vector systems
A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element...
US-9,493,767 Method for screening for high L-tryptophan producing microorganisms using riboswitch
A method of screening a high L-tryptophan-producing microorganism using a riboswitch is provided. More particularly, a riboswitch for screening a high...
US-9,493,766 PCR reaction cleanup buffers
The present disclosure relates to buffers containing polyols for use with affinity-binding and/or magnetically susceptible thermoplastic particles and methods...
US-9,493,765 Compact subnanosecond high voltage pulse generation system for cell electro-manipulation
Disclosed are methods and systems for subnanosecond rise time high voltage (HV) electric pulse delivery to biological loads. The system includes an imaging...
US-9,493,764 Hybrid electronic sheets
Provided is an electronic sheet including a graphitic material and a phage which displays a peptide having a binding ability to the graphitic material on its...
US-9,493,763 Stabilized laccase enzyme and methods of making and using the same
Provided herein are compositions and methods for enhancing enzyme activity, half-life, thermostability, enhanced activity at elevated temperature, and/or...
US-9,493,762 Vector, a transformant and a method to produce a polypeptide having activity to selectively hydrolyze a...
An object of the present invention is to provide a means for producing an optically active tropic acid that is a compound useful as a synthetic raw material or...
US-9,493,761 Procoagulant molecular decoy for treating hemophilia A or B with or without inhibitor
The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to...
US-9,493,760 Fungal-specific metalloproteases and uses thereof
The present invention relates to methods of reducing, delaying, preventing and/or inhibiting the progression of a Cryptococcus infection into the central...
US-9,493,759 Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having aspartic endopeptidase activity and isolated polynucleotides encoding the polypeptides. The...
US-9,493,758 Subtilases
The present invention relates to methods for producing variants of a parent TY145 subtilase and of a parent BPN' subtilase and to TY145 and BPN' variants having...
US-9,493,757 Modified factor VII or factor VIIa polypeptides
The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in...
US-9,493,756 Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose
Described herein are methods and genetically engineered cells useful for uncapping a mannose-6-phosphate residue on an oligosaccharide.
US-9,493,755 Bacillus, hyaluronidase, and uses thereof
The present invention provides a bacillus sp. having a deposit access number of CGMCC NO. 5744 and a hyaluronidase produced by the bacillus and the amino acid...
US-9,493,754 Aspergillus containing beta-glucosidase, beta-glucosidases and nucleic acids encoding the same
A novel microorganism is provided named Aspergillus saccharolyticus. Further, beta-glucosidase enzymes encoded by said microorganism are provided, and the use...
US-9,493,753 Modified .alpha.-glucosidase and applications of same
The object is to provide an .alpha.-glucosidase in which a transglycosylation activity predominates, and use thereof, and the like. A modified...
US-9,493,752 Endoglycosidase from Streptococcus pyogenes and methods using it
The invention provides an endoglycosidase, referred to as EndoS49 and having the amino acid sequence of SEQ ID NO: 1. EndoS49 was isolated from Streptococcus...
US-9,493,751 Dual-functional hybrid glucanases
Described herein is a fusion polypeptide that contains (a) a first segment containing a Fibrobacter succinogenes 1,3-1,4-.beta.-D-glucanase (Fs.beta.-glucanase)...
US-9,493,750 DNA-binding proteins and uses thereof
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also...
US-9,493,749 Process modifications to enhance chlorophyll degradation
In one aspect, there is provided a process for treating a plant oil, comprising a step of contacting the oil with an enzyme, wherein the enzyme is capable of...
US-9,493,748 Method for treating pyropheophytin-containing compositions
The present invention provides methods and uses for treating pyropheophytin-containing compositions, particularly in order to remove pyropheophytin therefrom....
US-9,493,747 Engineered transglutaminase barrel proteins
Disclosed herein are methods and compositions related to engineered fragments of the human transglutaminase-related protein family, described herein as...
US-9,493,746 Enzyme used in biosynthesis of 1, 4-BDO and screening method of the same
Recombinant butyraldehyde dehydrogenases (Blds) with improved production of 1,4-BDO, as well as recombinant microorganisms comprising polynucleotides encoding...
US-9,493,745 Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using...
Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus...
US-9,493,744 Methods for viral inactivation and other adventitious agents
The invention provides for methods of viral inactivation using high temperature short time (HTST) treatment and adjustment of various parameters such that...
US-9,493,743 Production of a human beta cell line from an early post natal pancreas
The present invention relates to a method for preparing commercial scale quantities of human functional beta cells and to the establishment of cell lines from...
US-9,493,742 Purification of cell mixtures using molecular beacons targeting cell specific RNA
This disclosure is in the area of research and therapeutics. In certain embodiments, it provides methods to assist in the purification of cell mixtures, e.g.,...
US-9,493,741 Method for increasing the proportion of animal cells secreting galectin-9
The object of the present invention is to provide a cell that can exhibit physiological activity based on galectin-9, a method for producing the cell, and use...
US-9,493,740 Immunotherapy of cancer using genetically engineered GD2-specific T cells
The present invention concerns immunotherapy for cancers having cells that comprise the ganglioside GD2 antigen. In specific embodiment, T cells having a...
US-9,493,739 Composition for proliferating stem cells by activating notch signaling
The present invention relates to stem cells in which a gene that activates signaling is introduced and to a method for proliferating the stem cells. More...
US-9,493,738 Method for producing high yield attenuated Salmonella strains
This invention relates to a novel method for growing attenuated mutant Salmonella typhi strains lacking galactose epimerase activity and harboring a recombinant...
US-9,493,737 Method for purifying bacterial cells
The present invention relates to a process for providing purified bacteria-containing concentrates, comprising at least the steps of adding an aqueous solution...
US-9,493,736 Method for lysing cells
The present invention relates to a method for the lysis of cells, especially bacterial cells and the isolation of nucleic acids. The sample is treated with...
US-9,493,735 Bioreactor system and method of enhancing functionality of muscle cultured in vitro
A method of producing organized skeletal muscle tissue from precursor muscle cells in vitro comprises: (a) providing precursor muscle cells on a support in a...
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