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Patent # Description
US-9,493,431 Apoptosis-inducing agent for the treatment of cancer and immune and autoimmune diseases
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases...
US-9,493,430 Biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds as CETP inhibitors
The present invention provides biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds, isomers thereof, or pharmaceutically acceptable...
US-9,493,429 Substituted benzoxazoles and methods of use thereof
The invention provides compounds having the general formula (I): and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A,...
US-9,493,428 Process for the preparation of a chiral compound
The present invention relates to a process for the preparation of a compound of formula (V), in particular posaconazole, wherein said process comprises the...
US-9,493,427 Compounds for inflammation and immune-related uses
The invention relates to compounds of structural formula (I) and structural formula (VI): ##STR00001## or a pharmaceutically acceptable salt, solvate,...
US-9,493,426 Quinazolinone derivatives useful as FGFR kinase modulators
The invention relates to new quinazolinone derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of...
US-9,493,425 Method for preparation of benzimidazole derivatives
The present invention provides a method for preparing a compound with a benzimidazole structure with an excellent yield using a low-cost starting material, not...
US-9,493,424 Antifungal compound
There is provided compound for use in therapy, the compound comprising repeating units of hydrophilic heterocyclic amine monomers that are coupled by...
US-9,493,423 Compounds capable of inhibiting voltage gated calcium ion channel, and pharmaceutical compositions comprising...
Disclosed herein are an N-(pyrazolylmethyl)arylsulfonamide derivative useful as a calcium ion channel blocker, a pharmaceutically acceptable salt thereof, and...
US-9,493,422 Quinoid rylenedicarboximides as IR absorbers
Compounds of the general formula (I) ##STR00001## and compounds of the general formula (II) ##STR00002## Use of compounds (I) or (II) as visible or...
US-9,493,421 Acridinedione derivatives for treating pigmentation disorders and ageing of the skin
The present invention relates to a compound of general formula (I) in which: --R.sub.1 and R.sub.2 are simultaneously or independently H, OH, OCH.sub.3 or a...
US-9,493,420 Quinoline derivatives and uses thereof
This disclosure provides a new class of compounds referred to as "reversed chloroquines" (RCQs), which are highly effective against CQ.sup.R and CQ.sup.S...
US-9,493,419 Quinoline derivatives as anti-cancer agents
Quinoline derivatives showing anticancer activities against cancer cell lines of hepatocellular carcinoma (Hep3B), lung carcinoma (A549), esophageal squamous...
US-9,493,418 Method for producing purified amine compound
A method for producing a purified amine compound represented by the formula (1), including: step (A) of reacting a crude form of the amine compound represented...
US-9,493,417 Polymorphic forms of the sodium salt of ...
Disclosed are novel novel polymorphic solvated and desolvated forms of the sodium salt of ...
US-9,493,416 N-methyl-4-benzylcarbamidopyridinium chloride and a process for its preparation
The present application relates to a new salt of N-methyl-4-benzylcarbami-dopyridine, a process for its preparation, a pharmaceutical composition comprising...
US-9,493,415 Process for fluorinating compounds
Methods of preparing a fluorinated substrate by combining potassium fluoride, a quaternary ammonium salt, and a substrate substituted with at least one chloro,...
US-9,493,414 Development of novel detergents for use in PCR systems
This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain...
US-9,493,413 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also...
US-9,493,412 Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
The present invention provides compounds of Formula (I): (I), as defined in the specification and compositions comprising any of such novel compounds. These...
US-9,493,411 Pyrrole-3-carboxamide bromodomain inhibitors
The present invention provides for compounds of formula (I) ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.10 have any of the values defined in the...
US-9,493,410 Method for crystallization of 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]-ethyl]-1,3-propan- ...
A method for highly efficiently preparing high purity crystals of 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chloro-phenyl]-ethyl]-1,3-propa- nediol...
US-9,493,409 Process for the synthesis of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine
The present invention provides new intermediate compounds or formulae (III) and (IVa), and salts thereof, and their use in a new synthetic process for the...
US-9,493,408 Removal of ammonia in urea finishing
Disclosed is a method for the removal of ammonia from the off-gas of a finishing section of a urea production plant. The method comprises contacting the off-gas...
US-9,493,407 Urea granulation process with scrubbing system
Disclosed is a method for producing granular urea and reducing ammonia emissions in a gaseous waste stream of the urea granulation process. The method includes...
US-9,493,405 Method for producing linear pentenenitrile
A process is described for preparing 3-pentenenitrile, characterized by the following process steps: (a) isomerizing a reactant stream which comprises...
US-9,493,404 Oxo-nitrogenated complex of cobalt, catalytic system comprising said oxo-nitrogenated complex and process for...
The present invention relates to an oxo-nitrogenated complex of cobalt having the general formula (I) wherein the residues R.sub.1, R.sub.2, R.sub.3, X.sub.1...
US-9,493,403 Treating androgen decline in aging male (ADAM)-associated conditions with SARMs
This invention provides methods for treatment and inhibition of a male subject having an Androgen Decline in Aging Male (ADAM)-associated condition, for example...
US-9,493,402 Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of the chemotaxis of polymorphonucleate and...
(R)-2-Arylpropionamide compounds of formula (I), pharmaceutical preparations of the compounds and a process for making the compounds are described. ...
US-9,493,401 Glutamate derivatives for topical use as immunomodulatory active ingredient
The present invention relates to L-glutamate-derived compounds of general formula (I) in which the R radical is a linear or branched C.sub.5 to C.sub.2 alkyl...
US-9,493,400 Process for preparing fluoroleucine alkyl esters
This invention relates to a resolution process for the preparation of fluoroleucine alkyl esters.
US-9,493,399 Multi-branched mannich base corrosion inhibitor and preparation method thereof
The present invention relates to a multi-branched Mannich base corrosion inhibitor and the method for preparing thereof. The method comprises (1) adding...
US-9,493,398 Ether dye fixative agents and methods
Described are dye fixative agents, comprising an ether compound, including salts, of Formula I: wherein, R.sub.1 is, independently at each occurrence, C1-C6...
US-9,493,397 Ionomers and methods of making same and uses thereof
Ionomers comprising ionic groups such as, for example, tetraalkylammonium groups and methods of making such ionomers. For example, the ionomers can be produced...
US-9,493,396 Substituted naphthalene compounds as calcium sensing receptor modulators
The invention relates to naphthalene compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and...
US-9,493,395 Production of two esters using homogeneous catalyst
Disclosed is a process for preparing two esters by reacting an aldehyde with an alcohol in the presence of a ruthenium complex compound as a catalyst. The...
US-9,493,394 Photoaligning materials
The present invention relates to polymer, homo- or copolymer or oligomer for the photoalignment of liquid crystals, especially for the planar orientation of...
US-9,493,393 Separation of propionic acid from acrylic acid
A process is provided for chromatographically separating propionic acid from acrylic acid. By means of the inventive process, a reduced propionic acid content...
US-9,493,392 Simulated moving bed chromatographic separation process
The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product, from a feed mixture, which...
US-9,493,391 Process for beta-lactone production
The present application provides a method for producing an beta-lactone product. The method includes the steps of: reacting an epoxide, a solvent with a...
US-9,493,390 Process for preparing V-Ti-P catalysts for synthesis of 2,3-unsaturated carboxylic acids
The invention relates to a catalyst composition comprising a mixed oxide of vanadium, titanium, and phosphorus. The titanium component is derived from a...
US-9,493,389 Dicarboxylic acid production with enhanced energy recovery
The invention provides improved energy content in and shaft power recovery from off-gas from xylene oxidation reactions while at the same time minimizing...
US-9,493,388 Dicarboxylic acid production with direct fired off-gas heating
The invention provides improved energy content in and shaft power recovery from off-gas from xylene oxidation reactions while at the same time minimizing...
US-9,493,387 Dicarboxylic acid production with minimal wastewater generation
The invention provides improved energy content in and shaft power recovery from off-gas from xylene oxidation reactions while at the same time minimizing...
US-9,493,386 Method for supplying reaction gases in catalytic vapor phase oxidation process
A method for supplying reaction gases in which at least a material to be oxidized and a gas containing molecular oxygen are mixed and the resultant mixture is...
US-9,493,385 Process for the preparation of (3E, 7E)-homofarnesol
The present invention relates to new types of processes for the improved preparation of homofarnesol, in particular of (3E,7E)-homofarnesol and homofarnesol...
US-9,493,384 Process for producing 2,3,3,3-tetrafluoropropene
The present invention relates, in part, to the discovery that the presence of HF in a HCFC-244bb feedstream in a reaction for the preparation of HFO-1234yf...
US-9,493,383 Organic compound and organic light emitting device using the same
The present invention provides an organic light emitting device comprising a first electrode, at least one organic layer and a second electrode, laminated...
US-9,493,382 Process and composition for inhibiting the polymerization of cyclopentadiene compounds
A process for inhibiting the polymerization of cyclopentadiene compounds (B) by contacting the cyclopentadiene compound with a quinone methide compound (A) of...
US-9,493,381 Catalytic process for the conversion of a synthesis gas to hydrocarbons
Catalytic process for the partial conversion of a gaseous mixture containing carbon monoxide and hydrogen into a mixture of hydrocarbons, including bringing the...
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