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Patent # Description
US-9,498,510 Polypeptide, nucleotide sequence thereof, and method for using the same for preventing DNA synthesis and...
A polypeptide represented by SEQ ID NO: 1 and a method for treatment of a tumor and another disease associated with abnormal cell proliferation are described....
US-9,498,509 TIMP3 as VEGF inhibitor
Polypeptides or proteins comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) or variants of TIMP3 can be used to substantially inhibit vascular...
US-9,498,508 Pharmaceutical composition for treating cancers and preparation method therefor
A pharmaceutical composition for treating cancers and preparation method thereof. Said composition for treating cancers contains Chinese medicinal materials...
US-9,498,507 Antiviral composition
The present invention relates to a composition comprising extract of the plant Ficus arnottiana. The invention also relates to a process for the preparation of...
US-9,498,506 Pharmaceutical composition for preventing or treating thyroid diseases, comprising extract from Lonicera...
The present invention relates to a pharmaceutical composition for preventing or treating thyroid diseases and a food composition for improving thyroid function,...
US-9,498,505 Embelia concinna extract comprising flavonoids in cosmetic and pharmaceutical compositions
The present invention deals with an Embelia extract--preferably an extract from Embelia concinna titrated in flavonoids--, its process for preparation and its...
US-9,498,504 Process for the preparation of a pharmaceutically effective extract from Arthrospira sp.
A process for the preparation of a pharmaceutically effective extract from the cyanobacterium Arthrospira sp. having the following steps: extrusion of a powder...
US-9,498,503 Composition comprising probiotic bacteria for use in the treatment of immune disorders
The present invention relates to a composition comprising probiotic bacteria for the treatment of pathologies associated with alterations of the immune system....
US-9,498,502 Prevention and treatment of allergic diarrhea
Bifidobacterium breve CNCM I-3865 (NCC2950), a composition comprising Bifidobacterium breve CNCM I-3865 (NCC2950), and the use of Bifidobacterium breve CNCM...
US-9,498,501 Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed...
US-9,498,500 Method of washing adherent cell using trehalose-containing cell-washing solution
Methods of washing adherent cells, capable of effectively suppressing cell death due to proteolytic enzyme treatment for detaching the adherent cell from a...
US-9,498,499 Imaging-aided gene therapy using mesenchymal stem cells as target-delivery vehicle
Compositions and methods of use thereof encompass engineered mesenchymal stem cells as a vehicle to deliver secreted tissue necrosis factor-RGD4C fusion...
US-9,498,498 Adipose tissue mesenchymal stem cells and methods of use to treat or inhibit uterine disorders
There is a high stem cell therapy potential in the field of reproductive disorders. Endometriosis is a common finding in women with infertility. In addition...
US-9,498,497 Method of treating lung diseases using cells separated or proliferated from umbilical cord blood
There is provided a method of treating lung diseases including administering cells separated or proliferated from umbilical cord blood to a patient suffering...
US-9,498,496 Method for inducing immune tolerance using viable polymer-modified allogeneic leukocytes
This invention relates to cellular-based therapies for increasing the level of regulatory T cells (Treg) and/or decreasing the level of pro-inflammatory T cells...
US-9,498,495 Methods for in vitro differentiation of TH-17+ cells
The present invention is directed to an in vitro method for promoting differentiation and proliferation of human T helper lymphocytes that express IL17...
US-9,498,494 Glycosaminoglycans
Heparan sulphate HS/BMP2 is disclosed, together with the use of HS/BMP2 in the repair and regeneration of bone tissue.
US-9,498,493 Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo
The invention provides compositions comprising a carrier comprising a continuous phase of a hydrophobic substance, liposomes, and a polynucleotide, and methods...
US-9,498,492 Compositions including triciribine and taxanes and methods of use thereof
This application relates to combination therapies including triciribine and related compounds and taxanes and compositions with reduced toxicity for the...
US-9,498,491 Methods for extraction of bioactive polyelectrolytes from humified organic materials
Improved methods for the separation and isolation of bioactive polyelectrolytes, such as humic acid, fulvic acid, ulmic acid, and humin, from any one or a...
US-9,498,490 Method for treatment of disease with pure porcine monosialoganglioside GM1
A process for preparing pure monosialoganglioside GM1 in the form of its sodium salt. There is provided a process for the isolation and purification of...
US-9,498,489 Antimetabolite agent combinations in the treatment of cancer
A method treating cancer in a subject comprises administering to the subject a therapeutically effective amount of an antimetabolite agent that induces...
US-9,498,488 Method of treating acute coronary syndromes
The present invention relates to methods and compositions designed for the treatment or management of acute coronary syndromes, particularly, unstable angina...
US-9,498,487 Topical cromolyn formulations
The present invention provides a topical composition comprising (a) at least one delivery agent compound and (b) a cromoglycic acid compound. Methods of...
US-9,498,486 Method for controlled release oral dosage of a vitamin D compound
A stable, controlled release formulation for oral dosing of vitamin D compounds is disclosed. The formulation is prepared by incorporating one or more vitamin D...
US-9,498,485 Bioavailable solid state (17-.beta.)-hydroxy-4-androsten-3-one esters
Disclosed are bioavailable solid state (17-.beta.)-Hydroxy-4-Androsten-3-one esters suitable for pharmaceutical uses and administration to mammals in need of ...
US-9,498,484 Treatment of fibrosis using FXR ligands
The present invention relates to a method for inhibiting fibrosis that occurs in an organ where the farnesoid X receptor (FXR) is expressed. This method...
US-9,498,483 2,3,5-trisubstituted thiophene compounds and uses thereof
The present invention provides a compound of formula I: ##STR00001## a method for manufacturing the compounds of the invention, and its therapeutic uses. The...
US-9,498,482 Treatment of erectile dysfunction and other indications
The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of...
US-9,498,481 Cyclopropyl modulators of P2Y12 receptor
The present invention relates to new cyclopropyl modulators of P2Y12 receptor activity, pharmaceutical compositions thereof, and methods of use thereof. ...
US-9,498,480 Substituted azabicycles and use thereof
The present application relates to novel substituted azabicycles, to processes for their preparation, to their use alone or in combinations for the treatment...
US-9,498,479 Dihydropyrimidine compounds and their application in pharmaceuticals
Provided herein are dihydropyrimidine compounds and their pharmaceutical applications, especially for use in treating and preventing HBV diseases. Specifically,...
US-9,498,478 Spiro aminic compounds with NK1 antagonist activity
The invention concerns a spiro-amino compound of Formula (I), wherein A is selected from a 5- or 6-membered aromatic ring and a 5- or 6-membered heteroaromatic...
US-9,498,477 Compositions and uses thereof to ameliorate pain
Hydrazinopyridazines, fused hydrazinopyridazines, phenylethylhydrazines, or combinations thereof, compositions comprising hydrazinopyridazines, fused...
US-9,498,476 Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyrida- zin-3-amine
The present disclosure generally relates to a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazi- n-3-amine. The...
US-9,498,475 Benzamides
Novel benzamide derivatives of formula (I) ##STR00001## wherein W.sup.1, W.sup.2, R.sup.1 to R.sup.7, R.sup.6, X and Y have the meaning according to the...
US-9,498,474 Compositions of buprenorphine and .mu. Antagonists
The invention relates to a composition comprising buprenorphine and a .mu. opioid receptor antagonist, wherein the composition is characterized by an Agonist...
US-9,498,473 Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health...
Compositions of hepatic therapeutic actives from one or more acridone compounds, one or more xanthone compounds, one or more thioxanthone compounds, one or more...
US-9,498,472 Methods using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain...
Methods of treating, preventing or managing leukemias are disclosed. The methods encompass the administration of an immunomodulatory compound of the invention...
US-9,498,471 Use of CDK9 inhibitors to reduce cartilage degradation
The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors...
US-9,498,470 Antiviral drugs for treatment of arenavirus infection
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are...
US-9,498,469 Compositions and methods for enhancing brain function
Compositions and methods are provided that enhance cognition in a human to which the composition is orally administered. Remarkably, clinical studies have...
US-9,498,468 Rhinitis treatment regimens
A method of treating rhinitis and rhinorrhea includes taking a daytime oral dosage unit containing a non-sedating antihistamine for treating rhinitis and an...
US-9,498,467 Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
This invention relates to JAK selective inhibitors for use in treatment of chronic neutrophilic leukemia and atypical chronic myeloid leukemia in patients.
US-9,498,466 Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and...
US-9,498,465 Topical compositions in the form of a gel containing a particular solubilized retinoid
A composition in the form of a gel, preferably hydroglycolic, is described. The composition can include in a physiologically acceptable medium, at least one...
US-9,498,464 Treatment of arterial wall by combination of RAAS inhibitor and HMG-CoA reductase inhibitor
The present invention relates to a pharmaceutical combination composition comprising at least one renin-angiotensin-aldosterone system inhibitor in a...
US-9,498,463 Compound obtained from gamboge resin, and medical uses of the same
Disclosed herein are seventeen new compounds obtained from an acetone-extracted product of gamboge resin. The seventeen new compounds have activities in...
US-9,498,462 Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders
The invention relates to use of the trans-(E) isomer or isomeric mixtures containing specified ratios of the trans-(E) and cis-(Z) isomers of doxepin,...
US-9,498,461 Compositions and methods for the treatment of inflammatory bowel disease
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers,...
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