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Patent # Description
US-9,499,868 Determination of single nucleotide polymorphisms useful to predict response for glatiramer acetate
This invention provides a method for treating a human subject afflicted with multiple sclerosis or a single clinical attack consistent with multiple sclerosis...
US-9,499,867 Methods for diagnosing and assessing risk of developing glomerulosclerosis
This document features method related to variants in the Inverted Formin 2 (INF2) gene that are susceptibility to focal segmental glomerulosclerosis (FSGS). For...
US-9,499,866 Compositions and methods for detecting single nucleotide polymorphisms
Described herein are nucleic acid based probes and methods for discriminating and detecting single nucleotide variants in nucleic acid molecules (e.g., DNA)....
US-9,499,865 Detection and measurement of tissue-infiltrating lymphocytes
The present invention is drawn to methods for measuring numbers, levels, and/or ratios of cells, such as lymphocytes, infiltrated into a solid tissue, such as a...
US-9,499,864 Expression of FABP4 and other genes associated with bladder cancer progression
Disclosed are methods for predicting the risk of bladder cancer progression, including death from bladder cancer by determining gene expression levels of FABP4...
US-9,499,863 Reducing GC bias in DNA sequencing using nucleotide analogs
The present invention is directed to methods and compositions for long fragment read sequencing. The present invention encompasses methods and compositions for...
US-9,499,862 Phospholinked dye analogs with an amino acid linker
In various embodiments, the present invention provides fluorescent dyes that are linked to another species through an amino acid or peptide linker. In an...
US-9,499,861 Methods and systems for multiplex quantitative nucleic acid amplification
The present disclosure provides methods, devices and systems that enable simultaneous multiplexing amplification reaction and real-time detection in a single...
US-9,499,860 Primers and methods for nucleic acid amplification
A primer and method for amplification of a target nucleic acid, the primer adapted to conform into a conformation that dissociates from a complementary strand...
US-9,499,859 Method for detecting a circularized DNA, and use of said method for detecting mutations
The present invention relates to a method for detecting a circularized single-stranded DNA by means of the isothermal hyperbranched rolling circle amplification...
US-9,499,858 Immuno-amplification
A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically...
US-9,499,857 Selection of triploid CHO cells and cell lines expressing recombinant polypeptides as high producers
The present invention relates to a method for selecting for cells or cell lines that produce a recombinant protein/polypeptide in high yields, the method...
US-9,499,856 DDR2 mutations in squamous cell lung cancer
Methods for treating patients with squamous cell lung cancer, including detecting the presence of mutations in the discoidin domain receptor 2 (DDR2) gene.
US-9,499,855 Compositions, methods, and computer systems related to making and administering modified T cells
Embodiments described herein relate to methods, devices, and computer systems thereof for the derivation of T CAR libraries (Universal Subject or Individual...
US-9,499,854 Tyrosine kinase biosensors and methods of use
The claims describe a process for designing and validating peptide-based substrates for a specified kinase. The process uses a rational approach to design...
US-9,499,853 Biosensing system with extended lifetime via cofactor recycling
The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through...
US-9,499,852 Wound dressing
The invention provides vesicles that may be used in diagnosing infection, especially with infection by bacteria such as Staphylococcus aureus and Pseudomonas...
US-9,499,851 Wound healing metakaryotic stem cells and methods of use thereof
The invention provides methods of identifying wound healing metakaryotic stem cells, identifying molecules to modulate proliferation and/or migration of...
US-9,499,850 Modified influenza virus for monitoring and improving vaccine efficiency
The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of...
US-9,499,849 Processes for preparing tubulysins
Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for...
US-9,499,848 Methods for high fidelity production of long nucleic acid molecules
In a method for generating a long nucleic acid molecule, nucleic acids immobilized on a surface and having overlapping complementary sequences is released into...
US-9,499,847 Production of closed linear DNA using a palindromic sequence
A primer for the amplification of a DNA template comprising a protelomerase target sequence, particularly for production of closed linear DNA, which primer is...
US-9,499,846 Method for recycling flue gas
A method for converting flue gas into useable bio-oil based compounds using algae includes mixing flue gas with water, infusing the mixture with a lipid trigger...
US-9,499,845 Genetically engineered microorganisms that metabolize xylose
The invention provides methods of cultivating oil-bearing microbes using xylose as a fixed carbon source. Also provided are microorganisms that have been...
US-9,499,844 Compositions and methods for making and modifying oils
The invention provides novel methods for making or modifying oils, e.g., plant animal or microbial oils, such as vegetable oils or related compounds, that are...
US-9,499,843 Method of producing oil from a microorganism
The invention relates to a micro-organism comprising a hydrogenase enzyme system which is capable of converting carbon dioxide into formic acid and a second...
US-9,499,842 Altering the interface of hydrocarbon-coated surfaces
Methods and compositions are provided wherein microorganisms are used to alter the interface of hydrocarbons and hydrocarbon-coated surfaces to increase oil...
US-9,499,841 Cell suitable for fermentation of a mixed sugar composition
The present invention relates to a cell suitable for production of one or more fermentation product from a sugar composition comprising glucose, galactose,...
US-9,499,840 Powered stowable vehicle seat and associated seat frame assembly
A vehicle seat has a seat frame assembly including a seat base frame that may be shifted between a raised position and a lowered position, and a seatback frame...
US-9,499,839 Methods for fermenting carbohydrate-rich crops
A method for fermenting carbohydrate-rich crops is provided. Sugar beet, sugar cane, sweet sorghum, tropical maize hybrids and fruits are rich in simple sugars;...
US-9,499,838 Human artificial chromosome containing human antibody .lamda. light chain gene and non-human animal containing...
The present invention relates to a human artificial chromosome which is genetically transmissible to the next generation with high efficiency and the method for...
US-9,499,837 Methods and compositions for producing male sterile plants
Methods of making a targeted modification in a male fertility gene in the genome of a plant are disclosed. The methods involve contacting a plant cell with an...
US-9,499,836 Fertilization and fruit size
Plants having modulated expression of a HAF or BEE polypeptide and which modulate aspects of plant fertility, such as parthenocarpy, fertilization efficiency,...
US-9,499,835 Use of Cry1Da in combination with Cry1Be for management of resistant insects
The subject invention includes methods and plants for controlling fall army worm insects, said plants comprising a Cry1Da insecticidal protein and a Cry1Be...
US-9,499,834 Rice cultivar designated `CL151`
A novel rice cultivar, designated `CL151,` is disclosed. The invention relates to the seeds of rice cultivar `CL151,` to the plants of rice `CL151,` and to...
US-9,499,833 Wheat plants having increased resistance to imidazolinone herbicides
The present invention is directed to wheat plants having increased resistance to an imidazolinone herbicide. More particularly, the present invention includes...
US-9,499,832 Wheat plants having increased resistance to imidazolinone herbicides
The present invention is directed to wheat plants having increased resistance to an imidazolinone herbicide. More particularly, the present invention includes...
US-9,499,831 Plant transcription factors, promoters and uses thereof
Polynucleotide molecules encoding transcription factors, promoter elements, binding partners and methods of use in increasing drought tolerance, yield, and...
US-9,499,830 Gene inducing elongation of roots or increasing biomass, and use therefor
By increasing, in a plant, expression of a gene or the like encoding a novel CONSTANS-LIKE protein, it is possible to promote root elongation of the plant...
US-9,499,829 Processes for producing lipids
The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing...
US-9,499,828 Protein having glycoalkaloid biosynthetic enzyme activity and gene encoding the same
Disclosed is the provision of a DNA for a glycoalkaloid biosynthetic enzyme in a plant belonging to the family Solanaceae such as potatoes. Also disclosed is a...
US-9,499,827 Compositions and methods comprising sequences having meganuclease activity
Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs,...
US-9,499,826 Production of proteins in filamentous fungi
The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a...
US-9,499,825 Dual inducible system for the condensed single protein production system
The present invention provides a dual inducible system for single protein production, as well as a method of inducing high level protein expression using amino...
US-9,499,824 Transcriptional control in alicyclobacillus acidocaldarius and associated genes, proteins, and methods
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are...
US-9,499,823 Constructs expressing chimeric receptors and use thereof for the controlled activation of defence response to...
The present invention relates to a construct able to express in at least one plant tissue, a chimeric receptor, said chimeric receptor being essentially made of...
US-9,499,822 Method for selectively culturing microorganism using phosphite dehydrogenase gene as marker
A simple and inexpensive method for selectively culturing a microorganism which method makes it possible to selectively culture a microorganism of interest even...
US-9,499,821 Preventing or treating viral infection using an inhibitor of the LSD1 protein, a MAO inhibitor or an inhibitor...
An embodiment of the invention provides a method of preventing or treating a viral infection of a host, comprising administering to the host an effective amount...
US-9,499,820 Methods of eliminating or reducing expression of genes in filamentous fungal strains by transitive RNA interference
The present invention relates to methods of reducing or eliminating expression of a target gene in a filamentous fungal strain by transitive RNA interference.
US-9,499,819 Antisense compositions and methods of making and using same
The present invention provides pharmaceutical formulations for oral administration of antisense oligonucleotides, such as antisense oligonucleotides against...
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