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Patent # Description
US-9,499,818 Methods and means for efficient skipping of at least one of the exons 51-53, 55, 57 and 59 of the human...
The invention relates to a method where a molecule is used for inducing and/or promoting the skipping of at least one of the exons 51-53, 55, 57 and 59 of the...
US-9,499,817 Antisense polynucleotides to induce exon skipping and methods of treating dystrophies
Antisense polynucleotides and their use in pharmaceutical compositions to induce exon skipping in targeted exons of the gamma sarcoglycan gene are provided,...
US-9,499,816 Methods of novel therapeutic candidate identification through gene expression analysis in vascular related diseases
The present invention discloses multiple treatment regimens for vascular-related diseases and disorders. The present invention provides for methods of treating...
US-9,499,815 Multimer for immunostimulation
The invention relates to a multimeric non-coding nucleic acid molecule for modulating the activity of the human or animal immune system, and to a preparation...
US-9,499,814 Methods for identifying drug effects on a cell by determining changes in the cell's spliced message profile
The invention provides products of manufacture for screening for compositions that can modify a cell's gene expression profile, and methods for making and using...
US-9,499,813 Systems and methods for amplification and phage display
Embodiments of various aspects described herein are directed to amplification of biological entities, for example, for phage display. In one aspect, members of...
US-9,499,812 Nucleic acid sample preparation
The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices...
US-9,499,811 Ligation enhancement
Compositions and methods are provided for enhancing enzymatic ligation between nucleic acid fragments that relies on one or more small molecule enhancers having...
US-9,499,810 Thrombopoietic activity of tyrosyl-tRNA synthetase polypeptides
Thrombopoietic compositions are provided comprising tyrosyl tRNA synthetase polypeptides, including truncations and/or variants thereof. Also provided are...
US-9,499,809 CyaA-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune...
The invention relates to a chimeric protein comprising or consisting of, from N-terminal to C-terminal, (a) a N-terminal part of a Bordetella CyaA protein (b) a...
US-9,499,808 Using cytosine deaminases to diminish retroelement transfer from pigs to humans
Transgenic pigs that express one or more non-porcine cytosine deaminases are described as well as methods of making and using such pigs.
US-9,499,807 Serine protease molecules and therapies
Cell-targeted serine protease constructs are provided. Such constructs can be used in methods for targeted cell killing such as for treatment cell of...
US-9,499,806 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The...
US-9,499,805 Methods and compositions for synthetic RNA endonucleases
The present invention provides sequence specific restriction enzymes for site-specific cleavage of RNA, as well as methods of their use.
US-9,499,804 Cyclodextrin glucanotransferase
The present invention relates to a novel cyclodextrin glucanotransferase (CGTase) enzyme which is obtainable from Clostridium saccharoperbutylacetonicum N1-4,...
US-9,499,803 Variant LovD polypeptide
The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin. In particular, the...
US-9,499,802 Polypeptides having peroxygenase activity
The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates...
US-9,499,801 Polypeptides having peroxygenase activity
The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates...
US-9,499,800 Methods of making and using chemically self assembled-nanorings
Provided herein are compounds, conjugates and methods for making lipid-chemically self-assembled nanorings (Lipid-CSANs) and using them to treat diseases and...
US-9,499,799 Cells and methodology to generate non-segmented negative-strand RNA viruses
The present invention relates to recombinant cells as well as to methods for the generation of non-segmented negative-sense single-stranded RNA viruses (NNV or...
US-9,499,798 Method for inducing fusion of dendritic cell with tumour cell
Disclosed in the present invention is a method for inducing the fusion of a dendritic cell with a tumour cell, in the fusion process, successively adding an...
US-9,499,797 Method of making induced pluripotent stem cells
A method of producing an induced pluripotent stem cell includes introducing into a somatic cell one or more non-viral expression vectors. The vectors include...
US-9,499,796 Isolated multipotent mesenchymal stem cell from human adult glomeruli (HGL-MSC), a method of preparing thereof...
The invention relates to an isolated multipotent glomerular mesenchymal stem cell derived from adult human kidney (hGL-MSC), which is characterized by the...
US-9,499,795 PDX1-expressing dorsal and ventral foregut endoderm
Disclosed herein are cell cultures comprising dorsal and/or ventral PDX1-positive foregut endoderm cells and methods of producing the same. Also disclosed...
US-9,499,794 Maintenance of differentiated cells with laminins
The present disclosure describes methods of maintaining the phenotype of differentiated cells. Generally, the natural environment of the body is replicated for...
US-9,499,793 Downregulation of miR-7 for promotion of beta cell differentiation and insulin production
A method of ex-vivo increasing insulin content in beta cells or stem cells is disclosed. The method comprising contacting the beta cells or stem cells with an...
US-9,499,792 Methods for obtaining stem cells
The present invention relates to methods for obtaining stem cells from mammalian cadavers, methods for obtaining or purifying stem cells from a sample likely to...
US-9,499,791 Skeletal muscle augmentation utilizing muscle-derived progenitor compositions, and treatments thereof
The present invention provides muscle-derived progenitor cells (MDCs) that show long-term survival following transplantation into body tissues and which can...
US-9,499,790 Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
The present invention relates to a composition for promoting differentiation of pluripotent stem cells into cardiac muscle cells, and a method for inducing...
US-9,499,789 Method for producing dendritic cells from pluripotent stem cells
A dendritic cell is produced from pluripotent stem cells by culturing pluripotent stem cells by the following steps: (1) performing adherent culture in a medium...
US-9,499,788 Cell line of lymphocytes comprising gamma-delta T cells, composition and production method thereof
The present invention relates to a cell line of lymphocytes comprising .gamma..delta. T cells, composition and production method thereof, and medical use namely...
US-9,499,787 Method for differentiating stem cells into neurons
The present invention relates to a method for differentiating stem cells into neurons, and is characterized in that stem cells are treated with a culture...
US-9,499,786 Enriched population of human pluripotent cells with Oct-4 and Sox2 integrated into their genome
The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of...
US-9,499,785 Isolating a mammalian embryonic stem cell from a homogenous pluripotent outgrowth of a mammalian...
The present invention provides a method of isolating a pluripotent cell from a pre-implantation embryo without isolation of the pluripotent cells from other...
US-9,499,784 Process for production of microalgae, cyanobacteria and metabolites thereof including lipids and carbohydrates
The present invention relates to processes for the production of microalgae, cyanobacteria and/or metabolites thereof. Described herein is a process involving,...
US-9,499,783 Production apparatus of sugar solution and production system of sugar solution
A sugar solution production apparatus includes a saccharification tank that obtains a saccharified solution containing a solid substance from a ...
US-9,499,782 Automatic aseptic sampling valve for sampling from enclosed containers
A sample can be collected from an enclosed container by opening a sample collection valve and drawing the sample from the enclosed container. After delivery of...
US-9,499,781 Disposable bioreactor condenser bag and filter heater
Disclosed herein is a system and method for condensing moisture in a moist gas stream entering a bioreactor or leaving a bioreactor, forming a dry gas stream...
US-9,499,780 Advanced tissue engineering system
The invention is an automated advanced tissue engineering system that comprises a housing in which one or more tissue engineering modules are accommodated...
US-9,499,779 Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one...
US-9,499,778 Automated intracytoplasmic sperm injection assisted fertilization system
An integrated automated system comprising a microfluidic cassette, and methods of use thereof, for intracytoplasmic sperm injection assisted fertilization. The...
US-9,499,777 Process for producing malt-based drink from malt fractioned by tissue
A process for producing malt-based beverage, in which any components, affecting flavor, foam quality, flavor stability and haze stability, of the malt-based...
US-9,499,776 System and method for all-in-one wort preparation
The present invention provides a brewing system that includes a cooking vessel configured to heat a fluid in the cooking vessel; a grain container having a...
US-9,499,775 Detergent composition comprising bluing agent and rapidly water-soluble brightener
A solid laundry detergent composition having: (a) detersive surfactant; (b) bluing agent; (c) C.I. fluorescent brightener 260; and (d) optionally, one or more...
US-9,499,774 Targeted performance of hypohalite methods thereof
This invention relates to extend the benefits of using hypochlorite compounds such as sodium hypochlorite to clean and disinfect articles while reducing or...
US-9,499,773 Enzyme particles comprising a vinyl pyrrolidone/vinyl acetate copolymer
The present invention relates to a particle comprising an enzyme and a polymer wherein the enzyme and polymer is present as a mixture in the particle and the...
US-9,499,772 Methods of decontaminating surfaces and related compositions
A composition of matter includes water, at least one acid, at least one surfactant, at least one fluoride salt, and ammonium nitrate. A method of ...
US-9,499,771 Fabric and surface care formulations containing tertiary amino modified cellulose derivatives
Described are fabric and surface care compositions comprising a tertiary amine substituted cellulose derivative and at least one surfactant.
US-9,499,770 Freshening compositions resisting scent habituation
The present application relates to perfume raw materials, perfume blends, perfume delivery systems and air care products comprising such perfume raw materials,...
US-9,499,769 Process for preparing polyurea microcapsules
The present invention relates to a process for producing microcapsules with a polyurea wall, as well as to the microcapsules themselves and consumer products...
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