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Patent # Description
US-9,504,762 Adeno-associated virus factor VIII vectors
The invention provides improved adeno-associated virus (AAV) Factor VIII (FVIII) vectors, including AAV FVIII vectors that produce a functional Factor VIII...
US-9,504,761 Stabilized chitosan-based nanoparticles and methods for making the same
A stabilized chitosan-based nanoparticle is provided having a chitosan polymer and a hydrophilic dispersing agent. In the stabilized nanoparticle, chains of the...
US-9,504,760 Immunomodulating nanoparticulate composition
The present invention relates to a preferably nebulizable pharmaceutical composition comprising a pharmaceutically acceptable protein-based nanocarrier...
US-9,504,759 Surface modified proteinaceous spherical particles and uses thereof
An aspect of embodiments of the invention relates to surface modified proteinaceous spherical particles (SMOP). SMOPs according to an embodiment of the...
US-9,504,758 Modified antibody, antibody-conjugate and process for the preparation thereof
An antibody comprising a GlcNAc--S(A).sub.x substituent is disclosed, wherein S(A).sub.x is a sugar derivative comprising x functional groups A wherein A is...
US-9,504,757 Site-specific GLP-2 conjugate using an immunoglobulin fragment
Provided are a glucagon-like peptide-2 (GLP-2) conjugate containing native GLP-2 or its derivative and an immunoglobulin Fc fragment being covalently linked via...
US-9,504,756 Self-stabilizing linker conjugates
The present invention provides Ligand-Drug Conjugates, Drug-Linkers, Linkers, and Ligand-Linker Conjugates comprising a self-stabilizing linker assembly component.
US-9,504,755 Multi-arm polymeric alkanoate conjugates
Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related...
US-9,504,754 Curcuminoid complexes with enhanced stability, solubility and/or bioavailability
Methods and materials relating to a medicament preparation comprising a curcuminoid component and a euradit component provided as a curcuminoid-eudragit...
US-9,504,753 Nanometer-sized prodrugs of NSAIDs
The present invention describes nanoprodrugs of non-steroidal anti-inflammatory drug (NSAIDs) and nanoprodrugs of .alpha.-lipoic acid-containing and NSAIDs....
US-9,504,752 Sterilizer, oral cavity sterilizer, sterilization method, sterilization apparatus, and sterilizer evaluation method
It is intended to provide a sterilizer, an oral cavity sterilizer, a sterilization method, a sterilization apparatus, and a sterilizer evaluation method capable...
US-9,504,751 Stable pharmaceutical composition
A pharmaceutical composition comprising: (a) a medium system, comprising a first component, a second component and a third component, wherein the first...
US-9,504,750 Stabilizing composition for biological materials
Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced...
US-9,504,749 Medical devices and methods comprising an adhesive sheet containing a drug depot
Improved medical devices and methods are provided that are implantable at or near a target tissue site beneath the skin of a patient, the medical device...
US-9,504,748 Aqueous silicone dispersions and their preparation
An aqueous dispersion comprises a silicone composition dispersed in an aqueous phase. The silicone composition comprises a product of a reaction of (a) an...
US-9,504,747 Lipids and lipid compositions for the delivery of active agents
This invention provides for a compound of formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1-R.sup.4, L and X are...
US-9,504,746 Pharmaceutical compositions of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinoli- ...
A pharmaceutical composition comprising: an active ingredient consisting of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quin- ...
US-9,504,745 Compositions and methods for cancer treatment using targeted carbon nanotubes
Compositions for detecting and/or destroying cancer tumors and/or cancer cells via photodynamic therapy are disclosed, as well as methods of use thereof. The...
US-9,504,744 Treatment of diffuse large-cell lymphoma with anti-CD20 antibody
The present invention concerns methods for the treatment of diffuse large cell lymphoma by administration of an anti-CD20 antibody and chemotherapy. Particular...
US-9,504,743 Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
This invention describes novel adjuvant compositions and formulations with excellent stability at refrigerated and room temperatures and up to and about...
US-9,504,742 Compositions for stimulation of mammalian innate immune resistance to pathogens
Embodiments of the invention are directed to methods of treating, inhibiting or attenuating a microbial infection in an individual who has or is at risk for...
US-9,504,741 Immune methods against influenza viruses and combinatorial vaccines thereof
The invention provides a method of preventing the spreading of influenza viruses, and the factors making up the said method, and especially provides one type of...
US-9,504,740 Haemophilus parasuis vaccine serovar type four
The present invention is a Haemophilus parasuis vaccine against serovar type 4 capable of triggering a protective immune response when administered to pigs as a...
US-9,504,739 Method of identifying a biologically-active composition from a biofilm
The subject invention provides materials and methods that effectively support innate immunity and/or disperse pathogenic biofilms using readily available,...
US-9,504,738 Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
Provided herein are compositions and methods for the treatment of cancers. The compositions comprise at least one VEGF peptide mimic, HER-2 epitope, immunogenic...
US-9,504,737 Immune response inducer
An immunity-inducing agent comprising as an effective ingredient a specific polypeptide is disclosed. These polypeptides were isolated, by the SEREX method...
US-9,504,736 Administration of serine protease inhibitors to the stomach
The inventors have unexpectedly discovered that shock and/or potential multi-organ failure due to shock can be effectively treated by administration of liquid...
US-9,504,735 Cell membrane translocation of regulated snare inhibitors, compositions therefor, and methods for treatment of...
Compositions and methods of modulating cellular function and treatment of disease in mammals comprising locally administering a regulated SNARE inhibitor and a...
US-9,504,734 Modified polynucleotides for the production of nuclear proteins
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
US-9,504,733 Regulation of energy metabolism and obesity by modulating a proliferation-inducing ligand (APRIL) or APRIL...
Provided herein are methods and compositions for modulating energy metabolism and weight in mammals, in particular by modulating thermogenesis associated with...
US-9,504,732 Methods for treating myocardial infarction comprising administering sonic hedgehog
The present invention relates to methods and pharmaceutical compositions for cardioprotection of subjects who experienced a myocardial infarction. In...
US-9,504,731 Therapeutic agent, treatment method and inspection method for diseases caused by activation of neutrophils
The present invention provides a therapeutic agent, a treatment method and an inspection method for diseases caused by activation of neutrophils. More...
US-9,504,730 Method of achieving a thymosin beta 4 concentration in a human patient
The present invention provides embodiments which involve methods of providing a predetermined concentration of thymosin beta 4 (TB4) at a predetermined time, t,...
US-9,504,729 Antiangiogenic small molecules and methods of use
Methods of inhibiting undesired angiogenesis are provided, which methods include administering to a subject a therapeutically effective amount of at least one...
US-9,504,728 Dosage form
There is provided inter alia a pharmaceutical dosage form for oral administration comprising a sanglifehrin as active ingredient in which the sanglifehrin...
US-9,504,727 Oral delivery of peptide pharmaceutical compositions
Bioavailability of peptide active agents to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the...
US-9,504,726 Topical skin care formulations comprising plant extracts
Disclosed are compositions that include extracts from a Lonicera maackii and Polygonum hydropiper.
US-9,504,725 Compositions and functional foods for treating and preventing obesity using polygonum cuspidatum butanol...
The present invention relates to the obesity-curative or obesity-preventive effect of a Polygonum cuspidatum butanol fraction and a Polygonum cuspidatum...
US-9,504,724 Pharmaceutical composition comprising extract of Puerariae flos for prevention and treatment of endometriosis
The present invention relates to a pharmaceutical composition containing Puerariae Flos extracts as active ingredients for preventing or treating endometriosis...
US-9,504,723 Medical cannabis lozenges and compositions thereof
A method for optimizing the therapeutic effects provided by CBD on the one hand, and the psychoactive effects provided by THC on the other hand, in a sublingual...
US-9,504,722 Anti-obese compositions containing holoptelea integrifolia extracts
The present invention discloses the extracts of Holoptelea integrifolia or the purified fractions isolated there from and the dietary, nutraceutical and...
US-9,504,721 Bacteriophage and its use for preventing proliferation of pathogenic bacteria
The present invention relates to a novel phage, which is newly isolated and identified, a composition for inhibiting growth of bacteria or killing thereof...
US-9,504,720 Substance for preventing and improving arthritis
This application provides a substance containing disrupted cells of an anti-inflammatory lactic acid bacterium and having an effect of preventing or improving...
US-9,504,719 Soft tissue repair and regeneration using postpartum-derived cells and cell products
Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and...
US-9,504,718 Methods of using adipose derived regenerative cells in the treatment of renal diseases and disorders
Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating...
US-9,504,717 Combined organ and hematopoietic cells for transplantation tolerance of HLA mismatched grafts
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to an HLA mismatched recipient, where tolerance to...
US-9,504,716 Methods of using adipose derived regenerative cells to promote restoration of intevertebral disc
Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating...
US-9,504,715 Enhancement of allogeneic hematopoietic stem cell transplantation
Methods and compositions are provided to augment the conversion of mixed hematopoietic cell chimerism to complete donor cell chimerism following allogeneic...
US-9,504,714 Method for treating blood plasma including a step of washing by means of dispersion
The present invention relates to a method for treating blood plasma including the steps of ethanol precipitation of the plasma or a fraction of plasma,...
US-9,504,713 Anti-glycation methods and compositions
The present invention comprises compositions that provide anti-glycation activity comprising a mineral extract composition or a mogroside/mineral extract...
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