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Patent # Description
US-9,504,712 Preparation for improving the action of receptors
The present invention relates to the use of polyunsaturated fatty acids and one or more components which have a beneficial effect on total methionine...
US-9,504,711 Zinc-enriched biomass, method for the preparation thereof and pro-biotic, cosmetic, dietary and nutraceutic...
The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus...
US-9,504,710 Stabilized chlorine dioxide to preserve carbohydrate feedstocks
A process to preserve a carbohydrate feedstock against contaminant microorganisms comprises contacting the carbohydrate feedstock with a stabilized chlorine...
US-9,504,709 Sodium nitrite-containing pharmaceutical compositions
Provided herein are pharmaceutically acceptable sodium nitrite and pharmaceutical compositions thereof. Also provided herein are methods for determining the...
US-9,504,708 Medicines for topic use based on sulfated hyaluronic acid as activating or inhibiting agent of the cytokine...
The object of the present invention relates to the new and surprising use of sulfated hyaluronic acid (HAS) as regulator agent of the cytokine activity (pro-...
US-9,504,707 Use of the modified polysaccharides for heparin neutralization
The subject of the invention is the use of cationically modified polysaccharides, except for chitosan, for direct neutralization of heparin in blood and...
US-9,504,706 Combination therapy for MDS
Disclosed are compositions and methods for the treatment of disorders such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The disclosed...
US-9,504,705 Hepatitis C viral infection treatment using a combination of compounds
Described herein is a combination that includes compound (A) of the formula ##STR00001## and compound (B) of the formula ##STR00002## or a pharmaceutically...
US-9,504,704 Topical pharmaceutical formulations containing a low concentration of benzoyl peroxide in suspension in water...
An aqueous formulation for topical application to the skin comprising water, a water-miscible organic solvent, and benzoyl peroxide, wherein the concentration...
US-9,504,703 Equol concentration increasing agent containing psicose as active ingredient
The present invention relates to a processed food composition containing, as an active ingredient, psicose, which is a saccharide having the function of...
US-9,504,702 Methods of inhibition of protein fucosylation in vivo using fucose analogs
The invention provides methods and compositions for the inhibition of fucosylation of proteins, including antibodies, in vivo by administration of a fucose analog.
US-9,504,701 Methods for treating viral infections using hydrogen sulfide donors
Certain embodiments are directed to methods of treating respiratory infection by administering an H.sub.2S donor.
US-9,504,700 Methods and compositions for stimulation and enhancement of regeneration of tissues
Methods and pharmaceutical compositions are provided for enhancing or stimulating regeneration of a tissue in a subject. In one aspect, the invention provides a...
US-9,504,699 Delayed-release glucocorticoid treatment of rheumatoid disease
The present invention refers to the treatment of a rheumatic disease and/or osteoarthritis by administering a delayed-release dosage form of a glucocorticoid to...
US-9,504,698 Flowable composition that sets to a substantially non-flowable state
Flowable compositions and methods are provided for delivering a therapeutic agent at or near a target tissue site beneath the skin of a patient, the flowable...
US-9,504,697 Progesterone treatment for improving sleep quality
Described herein are therapeutic methods using progesterone and progesterone analogs to improve sleep quality. The methods may be particularly useful to treat...
US-9,504,696 Intracameral sustained release therapeutic agent implants
Described herein are intracameral implants including at least one therapeutic agent for treatment of at least one ocular condition. The implants described...
US-9,504,695 Methods for reducing body fat
Provided are methods, compositions, systems, and kits for treating metabolic syndrome or a disorder associated with metabolic syndrome, e.g., obesity,...
US-9,504,694 Isoquinolidinobenzodiazepines
This disclosure provides novel isoquinolidinobenzodiazepines. These compounds can also be incorporated into antibody-drug conjugates.
US-9,504,693 Pharmaceutical compositions for the treatment of cancer and other diseases or disorders
This invention provides novel pharmaceutical compositions of the compound of formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, that are...
US-9,504,692 Selective inhibition of MALT1 protease by phenothiazine derivatives
The invention relates to a compound for use in treating a cancer, wherein the cancer depends on the proteolytic activity of the MALT1 protease, and wherein the...
US-9,504,691 Finafloxacin suspension compositions
The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a suspension...
US-9,504,690 Tetracyclic xanthene derivatives and methods of use thereof for the treatment of viral diseases
The present invention relates to novel Tetracyclic Xanthene Derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, Y.sup.1,...
US-9,504,689 Compounds and methods for antiviral treatment
Compounds and pharmaceutically acceptable salts and esters and compositions thereof, for treating viral infections are provided. The compounds and compositions...
US-9,504,688 Methods and compositions for treating bacterial infection
The present invention relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present invention...
US-9,504,687 Treating Bax(.DELTA.)2-positive cancer with chemotherapies targeting caspase 8
Discovery of a new Bax isoform, Bax.DELTA.2, in cancer cell lines and primary tumors is described. The Bax.DELTA.2 isoform resulted from combination of Bax...
US-9,504,686 ERK inhibitors and uses thereof
The present invention provides compounds, compositions thereof, and methods of using the same.
US-9,504,685 Method for treating a pulmonary hypertension condition
A method for treating a pulmonary hypertension condition such as pulmonary arterial hypertension (PAH) in a subject comprises administering to the subject a...
US-9,504,684 Syk inhibitors
The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and...
US-9,504,683 Heteroaryl derivatives as CFTR modulators
The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane...
US-9,504,682 Haptens of aripiprazole
The invention relates to compounds of Formula I, wherein R.sup.1, R.sup.2, and R.sup.3 are defined in the specification, useful for the synthesis of novel...
US-9,504,681 Controlled release hydrocodone formulations
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a...
US-9,504,680 Pyrrole derivatives as alpha 7 nAChR modulators
Disclosed are compounds of the formula (I), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and m are as described herein, as modulators...
US-9,504,679 Pharmaceutical compositions comprising glitazones and Nrf2 activators
The invention relates to pharmaceutical compositions comprising PPAR agonists and Nrf2 activators and methods of using combinations of PPAR agonists and Nrf2...
US-9,504,678 Oral dosage forms including an antiplatelet agent and an acid inhibitor
The present disclosure provides oral dosage forms comprising an antiplatelet agent and an acid inhibitor, as well as methods of treating subjects with an...
US-9,504,677 Substituted N-aryl pyridinones
Disclosed herein are substituted N-Aryl pyridinone fibrotic inhibitors and/or collagen infiltration modulators of Formula I, process of preparation thereof,...
US-9,504,676 Molecules inhibiting a metabolic pathway involving the Syk protein tyrosine kinase and method for identifying...
The present invention relates to the C-13 molecule (methyl 2-{5-[(3-benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}- -benzoate) and to organic...
US-9,504,675 Alpha-ketoheterocycles and methods of making and using
Compounds are disclosed that are effective in inhibition of fatty acid amide hydrolase, an enzyme responsible for catabolism of endogenous cannabinoids such as...
US-9,504,674 TrkB agonists and methods of use
Compounds and methods related to the activation of the TrkB receptor are provided. The methods include administering a 7,8-dihydroxyflavone derivative with...
US-9,504,673 Agent for the prophylaxis and treatment of highly pathogenic infectious diseases
The invention relates to an agent for the treatment and/or prophylaxis of highly pathogenic infectious diseases, such as highly pathogenic influenza A (in...
US-9,504,672 Compositions and methods for treating or preventing pneumovirus infection and associated diseases
The present invention provides novel crystalline polymorphic forms of MDT-637, in particular, crystalline polymorphic forms with physicochemical properties...
US-9,504,671 Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic...
This invention is directed to pharmaceutical compositions for topical administration to a mammal, wherein the pharmaceutical compositions comprise a...
US-9,504,670 Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of...
US-9,504,669 Spliceostatin analogs and methods for their preparation
The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the...
US-9,504,668 Phenyl alkyl carbamate compounds for use in preventing or treating epilepsy or epilepsy-related syndrome
The present invention provides a pharmaceutical composition for preventing and/or treating a epilepsy or epilepsy-related syndrome, for example an intractable...
US-9,504,667 Method for treating skin cancer
A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the...
US-9,504,666 Chloroprocaine-based pharmaceutical composition for repeated intrathecal administration
This invention relates to an injectable pharmaceutical composition based on chloroprocaine or salts and/or derivatives thereof for use in central loco-regional...
US-9,504,665 High-dose glycine as a treatment for obsessive-compulsive disorder and obsessive-compulsive spectrum disorders
The present invention provides for a method of treating OCD or an Obsessive-Compulsive Spectrum Disorder (OCSD), such as BDD or ADHD, using a high-dose glycine...
US-9,504,664 Compositions and methods for treating severe pain
The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a...
US-9,504,663 Composition for the treatment of cystic fibrosis
The present invention provides a composition comprising at least one prostacyclin or prostacyclin analog or a pharmaceutically acceptable salt thereof and at...
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