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Patent # Description
US-9,505,815 Heterogeneous nuclear ribonucleoprotein A2* (HNRNP A2*) and nucleic acid encoding the same
An hnRNP A2* protein, including an amino acid sequence represented by SEQ ID NO: 1. The protein is a complete protein, a protein fragment, a protein analog or a...
US-9,505,814 Manufacture of inter-alpha-inhibitor (IaIp) from plasma
The present invention provides compositions and pharmaceutical formulations of IaIp derived from plasma. Also provided are methods for the manufacture of the...
US-9,505,813 Use of GDF traps to treat anemia
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including...
US-9,505,812 Plasmodium falciparum antigens
The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response...
US-9,505,811 Plant CO.sub.2 sensors, nucleic acids encoding them, and methods for making and using them
The invention provides compositions and methods for manipulating the exchange of water and/or carbon dioxide (CO.sub.2) through plant stomata by controlling...
US-9,505,810 Toxins in type A Clostridium perfringens
The present disclosure relates to novel pore-forming toxins of Type A C. perfringens and immunogenic compositions and vaccines thereof. The present disclosure...
US-9,505,809 Proteins with repetitive bacterial-IG-like (BIG) domains present in Leptospira species
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive...
US-9,505,808 PCV2 ORF2 protein variant and virus like particles composed thereof
Vaccination methods to control PCV2 infection with different PCV2 subtypes are disclosed. Specifically, a PCV2 subtype b (PCV2b) ORF2 proteins or immunogenic...
US-9,505,807 Parainfluenza virus 5 based vaccines
The present invention provides safe, stable, efficacious, and cost-effective vaccines based on viral expression vectors that include a parainfluenza virus 5...
US-9,505,806 DNA vaccine, method of inducing the immune response, method of immunisation, antibodies specifically...
The object of the invention is a DNA vaccine, method of inducing the immune response, antibodies specifically recognizing the haemagglutinin H5 of an influenza...
US-9,505,805 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and...
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders,...
US-9,505,804 Peptidomimetic macrocycles
Provided herein are peptidomimetic macrocycles containing amino acid sequences with at least two modified amino acids that form an intramolecular cross-link...
US-9,505,803 Wash solution and method for affinity chromatography
The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, and a nonbuffering...
US-9,505,802 Method for protein isolation in anoxic conditions
The present invention relates to a method for the isolation of proteins that comprise disulfide-bonds in their native conformation. Essentially, a method of the...
US-9,505,801 Stabilized compounds having secondary structure motifs
The present invention provides novel stabilized crosslinked compounds having secondary structure motifs, libraries of these novel compounds, and methods for the...
US-9,505,800 Extended triterpene derivatives
The present invention concerns novel pharmaceutically active triterpene derivatives, pharmaceutical compositions containing the same, their use as medicaments,...
US-9,505,799 18F-labeled precursor of PET radioactive medical supplies, and preparation method thereof
The present invention relates to a precursor of positron emission tomography (PET) radioactive medical supplies, a preparation method thereof, and an...
US-9,505,798 Steroid compounds as RORyt modulators and uses thereof
Steroid compounds are disclosed that have a formula represented by the following: ##STR00001## and wherein m, n, t, u1, u2, v1, v2, R.sup.1a, R.sup.1b,...
US-9,505,797 Conversion of alpha-hydroxyalkylated residues in biomolecules using methyltransferases
The present invention relates to targeted conversion of alpha-hydroxyalkylated residues in biomolecules in the presence of a directing methyltransferase, namely...
US-9,505,796 Phosphorylated A2A receptor agonists
A phosphorylated A.sub.2A receptor agonist providing agonist properties on the A.sub.2A receptor after dephosphorylation the phosphorylated A.sub.2A receptor...
US-9,505,795 Method for producing scyllo-inositol
The disclosure provides a method of producing a scyllo-inositol or a new scyllo-inositol derivative in a one-step process, from ubiquitous and inexpensive raw...
US-9,505,794 Ruthenium (II) complexes, preparation and uses thereof
The present invention discloses novel Ruthenium (II) polypyridyl complexes, preparation and its application as DNA imaging agents.
US-9,505,793 Azine metal phosphates as flame-retardant materials
The present invention relates to azine metal phosphates, compositions containing the same, a process for preparing the same and their use as flame retardants....
US-9,505,792 Forms of cidofovir
Cidofovir is obtained in different forms, including amorphous cidofovir, crystalline anhydrous cidofovir, crystalline cidofovir monohydrate, and crystalline...
US-9,505,791 Prodrugs and methods of use thereof
The invention relates to compounds of use as targeted cytotoxic agents and methods of use thereof. In particular, the invention relates to prodrugs that are...
US-9,505,790 Silane compounds and their use in functionalizing solid supports and immobilizing biological molecules on these...
The invention relates to novel silane compounds corresponding to the following formula (I): A-E-X (I) in which: X represents a silylated group which makes...
US-9,505,789 Cyclization methods
The invention provides methods for cyclizing poly-yne compounds under mild conditions to provide cyclic compounds.
US-9,505,788 Process to prepare aluminoxanes by reaction of alkylaluminum with allylic alcohols
The present invention relates to a process to prepare alkylaluminoxanes by reaction of alkylaluminium with a substituted allylic alcohol of the formula wherein...
US-9,505,787 Process for preparing of bortezomib
The present invention provides improved processes for the preparation of Bortezomib, tert ...
US-9,505,786 Substituted annulated triazines and use thereof
The present application relates to novel substituted fused pyrimidines and triazines, to processes for their preparation, to their use alone or in combinations...
US-9,505,785 Pyridone and aza-pyridone compounds and methods of use
Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for...
US-9,505,784 Fused 2-aminothiazole compounds
The present application relates to therapeutic organic compounds, compositions comprising an effective amount of a therapeutic organic compound; and methods for...
US-9,505,783 Method of producing pyrone and pyridone derivatives
The present invention provides a pyrone derivative and a pyridone derivative, which are novel intermediates for synthesizing an anti-influenza drug, a method of...
US-9,505,782 Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof
The present disclosure relates generally to thienopyrimidine and thienopyridine compounds and methods of use thereof. In particular embodiments, the present...
US-9,505,781 Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof
The present disclosure relates generally to thienopyrimidine and thienopyridine compounds and methods of use thereof. In particular embodiments, the present...
US-9,505,780 Thienopyranones as kinase and epigenetic inhibitors
The invention relates to methods of treating diseases including but not limited to, cancer, non-cancer proliferative disease, sepsis, autoimmune disease, viral...
US-9,505,779 Tacrolimus analogues, a neuroprotective composition comprising the same, an immunosuppressive composition...
The present invention relates to novel tacrolimus analogs, a composition for the prevention or treatment of neurological diseases or immune hypersensitivity...
US-9,505,778 Monomers, polymers and articles containing the same from sugar derived compounds
Disclosed herein are monomers formed by reacting a sugar derived compound(s) comprising a lactone and two hydroxyls with a compound(s) comprising an isocyanate...
US-9,505,777 Method for preparing anhydrous sugar alcohol
The present invention relates to a method for preparing anhydrous sugar alcohol, and more particularly, to a cheap and highly efficient method for preparing...
US-9,505,776 Prodrugs of fumarates and their use in treating various diseases
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##
US-9,505,775 Inhibitors of cytomegalovirus
Compounds of Formula (I) wherein R.sup.1, R.sup.2, R.sup.3A, R.sup.3B, Y, Z.sup.1 and Z.sup.2 are defined herein, are useful for the treatment of ...
US-9,505,774 Polymorphic forms of icotinib maleate and uses thereof
Provided are Icotinib maleate (the compound of Formula I) and polymorph forms thereof, and methods of preparing and using them. ##STR00001##
US-9,505,773 Rapamycin analogues and their pharmaceutical use
Novel rapamycin analogues and methods for their production with FKBP and/or MIP inhibitory activity with reduced mTOR inhibitory activity with therapeutic...
US-9,505,772 Aromatic ring compound
The present invention provides an aromatic ring compound having a melanin-concentrating hormone receptor antagonistic action and useful as an agent for the...
US-9,505,771 Stable micronised monoclin form of asenapine maleate and its synthesis
A stable micronized monoclinic form of asenapine maleate is described, which comprises 5% by weight or less of orthorhombic form or any other crystalline form...
US-9,505,770 Organic photovoltaic devices comprising solution-processed substituted metal-phthalocyanines and exhibiting...
Organic photovoltaic (OPV) devices are disclosed. An exemplary device has first and second electrodes and an organic, photovoltaically active zone located...
US-9,505,769 Tetraaza-cyclopenta[a]indenyl derivatives
The present invention provides compounds of Formula (I) as M1 receptor positive allosteric modulators for the treatment of diseases mediated by the muscarinic...
US-9,505,768 Compositions and methods for modulating TLR4
Provided herein, inter alia, are methods and compositions for modulating TLR-4.
US-9,505,767 Pyrazolo[1,5-A]pyrimidin-7(4H)-onehistone demethylase inhibitors
The present invention relates to compounds formula (I): ##STR00001## and to salts thereof, wherein R.sup.1-R.sup.4 and A have any of the values defined in the...
US-9,505,766 Kinase inhibitors
Methods of inhibiting kinases using kinase inhibitors having olefin moieties are disclosed.
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