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Patent # Description
US-9,511,155 Compositions and methods for non-invasive imaging
The present invention relates to a novel composition useful in targeted diagnostic and/or therapy of a target site, such as cancerous tissue. The composition...
US-9,511,154 Process for the preparation of hyperpolarized derivatives for use in MRI analysis
The present invention relates to a process for the preparation of aqueous solutions of hyperpolarized carboxylic organic acids ready for use in in-vivo MR...
US-9,511,153 Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using...
Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy)phosphazene] and/or a derivatives...
US-9,511,152 Multicolored pH-activatable fluorescence nanoplatform
The present invention relates to pH-tunable, highly activatable multicolored fluorescent nanoplatforms and methods of using the nanoplatforms in a variety of...
US-9,511,151 Compositions and methods for the prevention and treatment of cancer
Conventional cancer immunotherapy falls short at efficiently expanding T cells that specifically target cancerous cells in numbers sufficient to significantly...
US-9,511,150 Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof
The invention provides novel chemical entities based on sugar alcohols. These new chemical entities are biocompatible and biodegradable. The molecules can be...
US-9,511,149 Fatty acid conjugates of quetiapine, process for making and using the same
The presently described technology provides a novel class of prodrugs of quetiapine that can be synthesized by chemically conjugating fatty acids to quetiapine....
US-9,511,147 Interpolymer network delivery system
This invention relates to compositions and applications for an mterpolymer network delivery system containing iodine.
US-9,511,146 Vitamin functionalized gel-forming block copolymers for biomedical applications
Gel-forming block copolymers were prepared comprising i) a central hydrophilic block consisting essentially of a divalent poly(ethylene oxide) chain and ii) two...
US-9,511,145 Stable tigecycline composition
The present invention relates to a stable pharmaceutical composition of Tigecycline and process for the preparation of the same. The composition comprises...
US-9,511,144 Cosmetic compositions and methods providing enhanced penetration of skin care actives
A cosmetic composition suitable for topical application is provided. In some examples, the cosmetic composition can include glycerin, hexyldecanol, a vitamin B...
US-9,511,143 Aqueous compositions comprising arbekacin
The invention provides aqueous liquid pharmaceutical compositions comprising arbekacin and chloride ions. The compositions are well tolerable for use in a...
US-9,511,142 Beta-lactamase inhibitors
Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit...
US-9,511,141 Composition for reducing oxidative stress and/or side effects occurring during cancer chemotherapy or improving...
Provided is a composition for reducing oxidative stress and/or side effects occurring during cancer chemotherapy or improving a nutritional status during cancer...
US-9,511,140 Stable VEGF antagonist formulations
Formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a...
US-9,511,139 Therapeutic combination and methods of treatment with a DLL4 antagonist and an anti-hypertensive agent
Methods for treating cancer comprising administering a DLL4 antagonist and one or more anti-hypertensive agents are described. Also described are pharmaceutical...
US-9,511,138 Pharmaceutical compositions comprising an antibody which binds the human anti-mullerian hormone receptor type II
The invention relates to novel pharmaceutical compositions including, as active ingredient, an antibody binding the human anti-Mullerian hormone type II...
US-9,511,137 Adjuvant for vaccines, vaccines that comprise said adjuvant and uses thereof
Adjuvant for vaccines that comprises a non-lipidated bacterial outer-membrane polypeptide (Omp), in which the bacteria may be of those of Brucella genus. The...
US-9,511,136 Immunogenic compounds comprising HIV GP41 peptide coupled to CRM197 carrier protein
The present invention relates to the field of vaccines directed against viruses of the HIV family. More particularly, it relates to an immunogenic compound...
US-9,511,135 Immunogenic respiratory syncytial virus glycoprotein-containing VLPs and related compositions, constructs, and...
The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of...
US-9,511,134 Inducing immune responses to influenza virus using polypeptide and nucleic acid compositions
The present invention provides polynucleotides and polypeptides capable of enhancing the immune response of a human in need of protection against influenza...
US-9,511,133 Vaccine against cholera and enterotoxigenic E. coli (ETEC) diarrhea
A vaccine against cholera and/or ETEC is provided, comprising a Vibrio cholerae O1 cell, characterized in that said cell comprises O1 antigens of both Ogawa and...
US-9,511,132 Mixing lyophilised meningococcal vaccines with D-T-Pa vaccines
A liquid D-T-Pa component is used to reconstitute a lyophilised meningococcal component, thereby producing a combined vaccine.
US-9,511,131 Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use
Chimeric fHBPs that can elicit antibodies that are bactericidal for different fHBP variant strains of N. meningitidis, and methods of use, are provided.
US-9,511,130 Escherichia coli vaccine combination
The invention provides an immunogenic composition comprising a combination of (i) bacterial Ig-like domain protein fragment (orf405B) having the amino acid...
US-9,511,129 Facultatively attenuated bacterial species and methods of preparation and use thereof
The present invention provides facultatively attenuated bacterial species and methods of preparation and use thereof. The term "facultatively attenuated" as...
US-9,511,128 Immunogenic epitopes for immunotherapy
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the...
US-9,511,127 Method to formulate T-cells
A method for formulating T-cells for use as a medicant comprises suspending T-cells with cross-linked surface moieties in a media suitable for infusion. The...
US-9,511,126 Proteolytic extract from bromelain for the treatment of connective tissue disorders
The present invention relates to a proteolytic extract obtained from bromelain for the treatment of connective tissue diseases. In particular, the present...
US-9,511,125 Methods and compositions for the treatment of influenza
A method to treat Influenza, and more particularly Influenza A Virus Subtype H1N1, with the use of a pharmaceutical composition comprising one or more digestive...
US-9,511,124 Anti-allergic substance, anti-allergic agent, and food
This invention provides an anti-allergic substance that effectively inhibits allergic symptoms by inhibiting production of the IgE antibody associated with the...
US-9,511,123 Combined use of a sulfated glycosaminoglycan and a hyaluronidase for improving the bioavailability of factor VIII
The present invention relates to pharmaceutical preparations comprising Factor VIII, a sulfated glycosaminoglycan and a hyaluronidase for the non-intravenous...
US-9,511,122 Dry growth hormone composition transiently linked to a polymer carrier
The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such...
US-9,511,121 Method for delivering exenatide to a patient in need thereof
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many...
US-9,511,120 Use of the angiotensin-(1-9) peptide or derivatives thereof, use of vectors overexpressing the ACE2 enzyme that...
The present invention is related to the use of the angiotensin-(1-9) peptide or peptides derived therefrom, which are biological or chemical analogs, for...
US-9,511,119 Preparations containing hepatocyte growth factor and hyaluronic acid and methods of making and using same
Preparations containing hepatocyte growth factor (HGF) and hyaluronic acid (HA) and methods of making and using same. The HGF and HA preparations can be...
US-9,511,118 Process for removing growth factors from platelets
A sub-atmospheric, negative pressure is applied to a growth factor starting material, such as whole blood, to release growth factors and plasma in a...
US-9,511,117 Treatment of muscular conditions and muscular dystrophies
The present invention provides methods for improving muscular function or treating a muscular disorder in an individual by administering to the individual a...
US-9,511,116 Stable MIA/CD-RAP formulation
The present invention relates to stable aqueous formulations comprising at least 5 mg/mL CD-RAP and a charged amino acid, said amino acid preferably having a...
US-9,511,115 Pharmaceutical compositions for treating or preventing bone conditions
Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same.
US-9,511,114 Neurotoxins exhibiting shortened biological activity
The present invention relates to the pharmaceutical field. Specifically, it contemplates a polynucleotide encoding a Neurotoxin polypeptide exhibiting a reduced...
US-9,511,113 Compositions and methods for affecting movement of contaminants, bodily fluids or other entities, and/or...
Method are described for inhibiting movement of a bodily fluid and/or contaminants on or in an animal comprising administering to the animal self-assembling...
US-9,511,112 Antibacterial composition for topical use
The present invention relates to an antibacterial composition, preferably for topical use, comprising triethyl citrate and a peptide consisting of 15 amino...
US-9,511,111 Methods for the treatment of X-linked hypophosphatemia and related disorders
The disclosure provides methods of treating X-linked hypophosphatemia, related bone demineralization and renal phosphate wasting disorders in a mammalian...
US-9,511,110 Generation of new pancreatic beta cells
The present invention relates to novel therapies for treatment of new and existing type 1 and type 2 diabetes, PreDiabetes, Latent Autoimmune Diabetes of...
US-9,511,109 Combination therapy with peptide epoxyketones
The invention provides combination therapy, wherein one or more other therapeutic agents are administered agents are administered with peptide epoxyketones or a...
US-9,511,108 Pharmaceutical composition for preventing and treating chronic obstructive pulmonary diseases, containing...
The present invention relates to a method for treating chronic obstructive pulmonary disease (COPD) comprising the step of administering the extract of...
US-9,511,107 Phenolic compositions derived from apple skin and uses thereof
Described herein are phenolic compositions derived from apple skins. In particular, described herein are flavonoid-rich fractions derived from apple skin...
US-9,511,106 Plant derived seed extract rich in essential fatty acids derived from perilla seed: composition of matter,...
A composition of matter comprises a shelf stable, super critical, CO.sup.2 fluid extracted seed oil derived from a cracked biomass of perilla frutescens, the...
US-9,511,105 Piles treatment
The present invention provides ointment, suppository, and herbal tea modalities for the treatment of hemorrhoids. The ointment and suppository modalities...
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