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Apparatus and process for preparing reactive lignin with high yield from
plant biomass for production of fuels...
Provided are methods for aqueous isolation of depolymerized lignin in high yield from a lignin-containing biomass composition, comprising positioning a...
Group 5 cyclopentadienyl transition metal-containing precursors for
deposition of group 5 transition...
Transition metal-containing precursors are disclosed. Also disclosed are methods of synthesizing and using the disclosed precursors to deposit transition...
Method for producing fluorine-containing substituted compound and
fluorine-containing substituted compound
A method for producing a fluorine-containing substituted compound, the method including: introducing an organofluorine compound and an organolithium compound...
Siloxane compound and process for producing the same
A siloxane compound comprises a plurality of siloxane repeating units and at least a portion of the siloxane repeating units are cyclosiloxane repeating units...
Ester-functional silanes and the preparation and use thereof; and use of
iminium compounds as phase transfer...
A method for producing a reaction product comprising an ester-functional silane, the method comprising: i) reacting a composition comprising: a) a ...
A method (P) for hydrosilylating at least one compound (C), including at least one unsaturation in the presence of an organosilicon compound (O) including at...
Use of cyclohexa-2,5-dien-1-yl-silanes as precursors for gaseous
A method of making hydrosilanes having a formula R.sup.1R.sup.2R.sup.3SiH by reacting a compound having formula I: ##STR00001## in solution using a strong...
Catalytic method for obtaining substituted (triorganosilyl)alkynes and
New (triorganosilyl)alkynes and their derivatives having general formula R.sup.1--C.ident.C--Z are provided along with methods for the preparation of...
Compounds containing hydrido-tricyano-borate anions
The present invention relates to compounds containing hydrido-tricyano-borate anions, their preparation and their use, in particular as part of electrolyte...
Trifluoroborate mass spectrometric tags
The invention provides compositions and methods for mass spectrometric (MS), organic synthesis, and applications of organo-trifluoroborate, for example, as mass...
The present invention relates to a class of novel isothiazolo[4,3-b]pyridine derivatives and a method for their preparation, as well as to pharmaceutical...
IRAK inhibitors and uses thereof
The present invention provides compounds of the general formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein each variable is as...
Imidazothiadiazole and imidazopyridazine derivatives as protease activated
receptor 4 (PAR4) inhibitors for...
The present invention provides imidazothiadiazole compounds of Formula (I); Wherein W, Y, R.sup.0, R.sup.2, R.sup.4, R.sup.a, R.sup.b, X.sup.1, X.sup.2, X.sup.3...
Organic electroluminescent materials and devices
A new class of compounds containing aza-dibenzothiophene or aza-dibenzofuran are provided. The compounds may be used in organic light emitting devices giving...
Compounds and compositions for use in phototherapy and in treatment of
ocular neovascular disease and cancers
The invention relates generally to anti-angiogenesis agents and related methods of using to anti-angiogenesis agents for biomedical applications including...
Substituted pyrazolylpyrazole derivative and use of same as herbicide
Provided is a compound capable of effectively control worst weeds of higher leaf stages that present practical problems. A specific pyrazolylpyrazole derivative...
Substituted pyrrolo[3,4-c]pyrazoles as PKC kinase inhibitors
The present invention relates to compounds and pharmaceutically acceptable salts of Formulas A and B: ##STR00001## wherein A, B, R.sup.1, R.sup.2, R.sup.3,...
Inhibitor crystalline form and preparation method and use thereof
The present invention relates to new crystalline forms of the inhibitor, 5-fluoro-3-phenyl-2-[(S)-1-(9H-purin-6-ylamino)-propyl]-3H-quinazoline-4-- one; the...
Process for the preparation of
The invention relates to an improved process for synthesizing N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-- ...
Derivatives and methods of treating hepatitis B infections
Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of...
Inhibitors of influenza viruses replication
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample...
Imidazopyridyl compounds as aldosterone synthase inhibitors
This invention relates to imidazopyridyl compounds of the structural formula: ##STR00001## or their pharmaceutically acceptable salts, wherein the variable...
2-(azaindol-2-yl) benz imidazoles as PAD4 inhibitors
Compounds of formula (I) wherein; R.sub.1 is hydrogen or C.sub.1-6alkyl; R.sub.2 is hydrogen, C.sub.1-6alkyl, perhalomethylC.sub.0-5alkyl-O--, or ...
Fluorinated integrin antagonists
The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to...
Pyrazolopyridines and pyrazolopyrimidines
A compound having the structure: ##STR00001## or a pharmaceutically acceptable salt or solvate thereof, wherein A and A' are C or N, where C may be...
Pyrroloquinoline alkaloids as antimalarial agents and process for the
The patent provides novel compounds with potential anti-malarial activity and process of synthesis thereof. Further, the process for the synthesis of known...
Cyclohexyl and quinuclidinyl carbamate derivatives having .beta.2
adrenergic agonist and M3 muscarinic...
The present invention relates to novel compounds having .beta.2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions...
Salt forms of (S)-quinuclidin-3-yl
The present invention relates to novel salt forms of (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate useful as an inhibitor of...
Process for the preparation of teneligliptin
A process for the preparation of teneligliptin.
Process for the industrial synthesis of lurasidone
Disclosed is a process for the industrial synthesis of Lurasidone from (1R,2R)-cyclohexane-1,2-diyldimethanol (1), 3-(piperazin-1-yl)benzo[d]isothiazole (3)...
Substituted aminopyrimidine compounds and methods of use
The invention relates to the preparation and use of new aminopyrimidine derivatives as drug candidates in free form or in pharmaceutically acceptable salt form...
Process for manufacturing benzoxazinones
The present invention relates to a process for manufacturing benzoxazinones of formula (I), ##STR00001## wherein the variables are defined according to the...
Prostaglandin receptor EP2 antagonists, derivatives, compositions, and
uses related thereto
The present invention is directed to compounds of Formula IC: ##STR00001## wherein the substituents are described herein. These compounds and their...
Method for preparing
The present invention relates to a novel method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)pi- ...
Nitrogen-containing heterocyclic compound
The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the...
zolidine-2,4-dione and drug...
Provided is (+)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2H)-yl)methyl]imid- azolidine-2,4-dione or a salt thereof. Also provided is a drug containing ...
Described are GCF-8 inhibitors of the formula (I), ##STR00001## and pharmaceutically acceptable salts thereof, wherein n, R.sup.1, R.sup.2, R.sup.5, R.sup.6,...
Polymer-fixed derivatives of dithiolane or dithiane
Derivatives of 1,3-dithianes and 1,3-dithiolanes of the general formula 1a ##STR00001## or salts thereof of the general formula 1b ##STR00002## where...
Condensation product of theanine derivative and carboxylic acid coumarin
derivative, its intermediate,...
The present invention relates to a compound as represented by formula (I), which is a condensation product of a theanine derivative and a carboxylic acid...
Method for producing N,N-dialkylhomofarnesic acid amide
Provided are: a method for producing N,N-dialkylhomofarnesic acid amide, which is a precursor of (.+-.)-3a,6,6,9a-tetramethyldodecahydronaphtho[2.1-b]furan that...
Method for producing ethylene oxide
[Problem] To provide a novel technology by which energy efficiency can be further improved in a process for producing ethylene oxide. [Solution] A method for...
Method for preparing glycidol using glycerol and glycidol obtained thereby
A method for preparing glycidol using glycerol includes mixing glycerol with urea in the presence of at least one zinc-based catalyst selected from the group...
Synthesis of chiral enaminones, their derivatives, and bioactivity studies
This invention provides enantioenriched heterocyclic enaminone compounds with quaternary stereogenic centers and novel methods of preparing the compounds....
The present invention provides (4E)-4-(4-substituted benzylideneamino)-2,3-dihydro-3-substituted-2-thioxothiazole-5-carbonitri- les of general formula A, below,...
Small molecule inhibitors of USP1 deubiquitinating enzyme activity
Provided are small molecule inhibitors of ubiquitin specific protease 1 (USP1) activity and methods for their use in treating and characterizing cancers. The...
Photo-sensitive resin composition, cured film, method for forming a pixel,
solid state image sensor, color...
Provided is a photo-sensitive composition capable of yielding pixels having a high translucency and a large refractive index, with a less amount of development...
Purification of aryltriazoles
Impure aryltriazoles such as benzotriazole and tolyltriazole that are contaminated with dark colored impurities can be purified by conversion to an aryltriazole...
Certain chemical entities, compositions, and methods
Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or...
Process for the preparation of Rosuvastatin calcium and preparation of its
The present invention relates to process for the preparation of 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrim- ...
The present invention in one embodiment provides a compound of Formula I, or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula...