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Patent # Description
US-9,523,121 Methods and compositions for PCR using blocked and universal primers
Provided herein are methods and compositions for performing PCR with primers with blocked 3'-ends that are unblocked when these primers anneal to the template....
US-9,523,120 Method of amplifying a nucleic acid
A nucleic acid amplification method is provided, along with kits useful in performing the amplification method.
US-9,523,119 Method of distinguishing genotypes
The present invention relates to a method of distinguishing genotypes using PCR-PHFA including: a nucleic acid amplification step in which a mutation...
US-9,523,118 Method of detecting nucleic acids containing a genetic variation
Provided are a composition or a kit for detecting a nucleic acid with genetic variation including a first amplification blocking nucleic acid and a second...
US-9,523,117 Gene analysis method using SDL-PCR
The present invention relates to a method for analyzing genes using SDL-PCR (separation of displaced ligation probe-based PCR), and more particularly to a...
US-9,523,116 Multiplexed digital assay with data exclusion for calculation of target levels
Digital assay system, including methods and apparatus, for calculating a level of one or more targets. In an exemplary method, data for amplification of a...
US-9,523,115 Compositions and methods for obtaining nucleic acids from sputum
The present invention relates to compositions and methods for preserving and extracting nucleic acids from saliva. The compositions include a chelating agent, a...
US-9,523,114 Analyzer
An object of the present invention relates to providing a nucleic acid analyzer capable of testing a plurality of test items in parallel, and of obtaining high...
US-9,523,113 Treatment of .alpha.-galactosidase A deficiency
The invention provides methods of treating .alpha.-galactosidase A deficiency. Dosage forms, methods of administration, and methods of analyzing human...
US-9,523,112 Method for the determination of the presence of an antibiotic in a fluid
The present invention provides a method and test for the determination of the presence or absence of an antibiotic in a sample such as milk.
US-9,523,111 Diagnostic apparatus and diagnostic method using the same
Provided is a diagnostic apparatus. The diagnostic apparatus includes a microfluidic chip including first and second measurement parts for respectively...
US-9,523,110 Culture containers with internal top coating over gas barrier coating and associated methods
A container for culturing a test sample includes a molded monolithic single layer polymeric container body having an upwardly extending, visually transmissive...
US-9,523,109 Method for enzymatically preparing peptides for use in improvement of brain function
The invention provides a method for preparing a peptide for improving brain function, comprising hydrolyzing milk casein with an enzymatic catalyst comprising a...
US-9,523,108 Thermostable .beta.-xylosidase
A thermostable .beta.-xylosidase, having a .beta.-xylosidase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by SEQ...
US-9,523,107 Immobilized transaminases and process for making and using immobilized transaminase
The invention is directed to immobilized transaminases and methods of making and using them.
US-9,523,106 Process for the enzymatic production of carnitine from beta-lactones
Subject of the invention is a process for the production of L-carnitine, wherein a .beta.-lactone, which is a 4-(halomethyl)oxetane-2-one, is converted into...
US-9,523,105 Fermentation route for the production of levulinic acid, levulinate esters and valerolactone and derivatives...
The invention provides processes for the conversion of pyruvate obtained from sugars or other carbon sources, to valuable C5 materials such as levulinic acid,...
US-9,523,104 Processes and systems for the production of alcohols
The present invention relates to processes and systems for the production of fermentative products such as ethanol and butanol. The present invention also...
US-9,523,103 Apparatus and process for fermentation of biomass hydrolysate
A process for converting biomass hydrolysate into biofuel, the process comprising the steps of: obtaining a biomass hydrolysate solution comprising...
US-9,523,102 Methods of anaerobic digestion of biomass to produce biogas
Improved methods for anaerobic digestion of organic matter to produce biogas. Among the improvements given are including ferric iron in a hydrolysis reactor to...
US-9,523,101 Protein and nucleic acid delivery vehicles, components and mechanisms thereof
Complex viruses are assembled from simple protein subunits by sequential and irreversible assembly. During genome packaging in bacteriophages, a powerful...
US-9,523,100 Pesticidal compositions and related methods
A process of applying a pesticidal composition to an area to control a pest, wherein the pesticidal composition comprises at least one compound selected from a...
US-9,523,099 Plant genes involved in nitrate uptake and metabolism
The present invention relates nucleic acid molecules that are modulated (e.g., upregulated) by nitrogen in corn, to proteins or polypeptides encoded by these...
US-9,523,098 Targeted modification of malate dehydrogenase
Disclosed herein are methods and compositions for targeted modification of one or more endogenous plant malate dehydrogenase genes.
US-9,523,097 Engineering rubber production in plants
The present invention relates to transplastomic guayule plants comprising chloroplasts engineered to express the complete cytosolic mevalonic acid (MEV) pathway.
US-9,523,096 Modified photosynthetic microorganisms for producing lipids
This disclosure describes genetically modified photosynthetic microorganisms, e.g., Cyanobacteria, that overexpress an acyl carrier protein (ACP), an acyl-ACP...
US-9,523,095 Microorganism expressing xylose isomerase
The present invention relates to a transformed microorganism capable of (a) a higher xylose isomerase activity than the equivalent microorganism prior to...
US-9,523,094 Methods of treating kennedy's disease
Certain embodiments are directed to methods of ameliorating, treating, or preventing Kennedy's Disease in a subject carrying a mutation in the Androgen Receptor...
US-9,523,093 Huntington's disease therapeutic compounds
The present invention is directed to RNA interference (RNAi) molecules targeted against a Huntington's disease nucleic acid sequence, and methods of using these...
US-9,523,092 Compatible display vector systems
The present invention provides a polynucleotide vector system used during polypeptide display that can be used to facilitate transfer of pools of ...
US-9,523,091 Nucleic-acid extraction method and nucleic-acid extraction cartridge
The present disclosure provides a nucleic-acid extraction method for carrying out the following procedures in the same cell, the procedures including:...
US-9,523,090 Compositions and methods for treating inflammation
Provided are electrokinetically-altered fluids (gas-enriched (e.g., oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of...
US-9,523,089 Manipulation of flavonoid biosynthesis in plants
The present invention relates to nucleic acids and nucleic acid fragments encoding amino acid sequences for flavonoid biosynthetic enzymes in plants, and the...
US-9,523,088 Modified proteases
This invention relates to modified polynucleotides encoding modified proteases, and methods for altering the production of proteases in microorganisms. In...
US-9,523,087 Cellulase variants with improved expression, activity and stability, and use thereof
The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity...
US-9,523,086 Protein extraction
A method for releasing the content of the periplasmic space of bacterial cells is provided, which comprises incubating the bacterial cells in a solution...
US-9,523,085 Thermostable type-A DNA polymerase mutants with increased polymerization rate and resistance to inhibitors
The present invention provides mutants of DNA polymerases having an increased rate of incorporation of nucleotides into nucleic acids undergoing polymerization...
US-9,523,084 Phosphodeoxyribosyl transferase mutant enzymes and uses thereof
The present invention relates to enzyme mutants obtained from the nucleoside deoxyribosyltransferase (NDT) of Lactobacilli bacteria. These mutants are...
US-9,523,083 Biochemical synthesis of 1,4-butanediamine
Process for biochemical synthesis of 1,4-butanediannine in a microorganism having an increased level of an ornithine decarboxylase activity as compared to the...
US-9,523,082 Firefly luciferase
The present invention relates to a luciferase derived from a Malaysian Luciola firefly, the luciferase having a maximum luminescent wavelength of 557 nm at pH...
US-9,523,081 Method for enhancing therapeutic effect of stem cells on autoimmune diseases, cardiovascular diseases, and/or...
A method for enhancing the therapeutic effect of a stem cell on autoimmune diseases, cardiovascular diseases, and/or hematological diseases is provided. The...
US-9,523,080 Stem cell culture medium and method of using said medium and the cells
The present invention relates to methods and compositions concerning isolation of proliferating cells. In particular, the invention regards enrichment of stem...
US-9,523,079 Cardiac repair by reprogramming of cardiac fibroblasts into cardiomyocytes
The present invention involves the use of transcription factors including Tbx5, Mef2C, Hand2, myocardin and Gata4 to reprogram cardiac fibroblasts into...
US-9,523,078 Method for increasing the E-selectin binding affinity of a population of cells expressing a CD44 polypeptide
The invention features methods and compositions for treating hematopoietic disorders, inflammatory conditions, and cancer and providing stem cell therapy in a...
US-9,523,077 Mature dendritic cell compositions and methods for culturing same
This invention provides methods to prepare and use immunostimulatory cells for enhancing an immune response. The invention provides a method for preparing...
US-9,523,076 Method for the identification and separation of non-regulatory T-cells from a mixture of regulatory T-cells
The present invention relates to a method of identifying and separating non-regulatory T-cells (conventional T-cells) from a mixture comprising regulatory...
US-9,523,075 Process for sorting motile particles from lesser-motile particles and apparatus suitable therfor
Motile particles are sorted from non-motile particles in a microfluidic sorting device wherein a stream of sort fluid containing motile and non-motile particles...
US-9,523,074 Sub-totipotent stem cell product and apparent hereditary modifying label thereof
Provided are a sub-totipotent stem cell product and epigenetic modification label thereof, a method for inducing the generation of the sub-totipotent stem cell...
US-9,523,073 Elisa for a naturally-occurring soluble truncated form of IL-23 receptor
A naturally-occurring soluble truncated IL-23R.alpha. protein (i.e., .DELTA.9 IL-23R.alpha.) is shown to be present in a biological sample and can serve as a...
US-9,523,072 Method for providing a circuit for biological liquid and circuit obtained
A circuit for biological liquid including a bag having two films and a press. The press includes two shells that clamp the bag in a state in which pipes are...
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