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Patent # Description
US-9,522,970 Comb polymers and use thereof for the production of active or effective ingredient formulations
The present invention relates to novel comb polymers, to a process for their manufacture and to the use thereof in the stabilization in an aqueous phase of...
US-9,522,969 Method for producing methacrylic polymer composition, and molded article
A method for producing a methacrylic polymer composition, which comprises a first polymerization step wherein a raw material composition A comprising a raw...
US-9,522,968 High performance Ziegler-Natta catalyst systems, process for producing such MgCl.sub.2 based catalysts and use...
Improved Ziegler-Natta catalysts and methods of making the improved catalyst are described. The Ziegler-Natta catalyst is formed using a spherical...
US-9,522,967 Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced...
A photopolymerization accelerator composition improving color stability and controlling polymerization shrinkage stress of cured resin and/or the resulting...
US-9,522,966 Hyaluronic acid derivative, method of preparation thereof, method of modification thereof and use thereof
The invention relates to the preparation and use of .alpha.,.beta.-unsaturated aldehyde of hyaluronan having a double bond in the positions 4 and 5 and an...
US-9,522,965 Sequential hydrothermal liquifaction (SEQHTL) for extraction of superior bio-oil and other organic compounds...
Methods of producing bio-fuel and other high-value products from oleaginous biomass (e.g. algae biomass) are provided. The two-step methods use a first step of...
US-9,522,964 Micronized starch and methods for manufacturing same
The present application is related to a micronized starch with an average particle size of less than 5 .mu.m and a degree of polymerization greater than 100,...
US-9,522,963 Dissolution of oxidized cellulose
A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled...
US-9,522,962 Peptides, conjugates and method for increasing immunogenicity of a vaccine
The present invention relates to conjugates comprising a peptide of at least 10 amino acid residues comprising the amino acid sequence GITELKKL (residues...
US-9,522,961 Protein complexes and methods of manufacturing bispecific antibodies using the protein complexes
A protein complex comprising (i) a first fusion protein comprising (a) a first polypeptide that comprises a first antigen-binding site and (b) a first binding...
US-9,522,960 Multispecific antibodies
The invention provides multispecific antibodies and methods of making and using such antibodies.
US-9,522,959 Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may...
US-9,522,958 Cancer targeted innate immunity
Provided is a cancer therapeutic agent comprising a cancer targeting molecule linked to a CpG oligodeoxynucleotide. Also provided are methods of reducing the...
US-9,522,957 Method of treating an inflammatory condition by administering toll-like 3 receptor antagonists
Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the...
US-9,522,956 Combination therapy using anti-EGFR and anti-HER2 antibodies
The invention relates to the combined use of anti-EGFR antibodies and anti-Her2 antibodies for the treatment of cancer, especially suitable for cancer...
US-9,522,955 Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment...
The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of a KDR-1121 or DC101 antibody, an extracellular hinge domain, a...
US-9,522,954 Anti-LRP5 antibodies and methods of use
The invention provides anti-LRP5 antibodies and methods of making and using the same.
US-9,522,953 Low acidic species compositions and methods for producing and using the same
The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods,...
US-9,522,952 Polypeptide binding to annexin A1 and use thereof
A polypeptide binding to Annexin A1, an antagonist against Annexin A1 including the polypeptide, an anti-Annexin A1 antibody including the polypeptide or an...
US-9,522,951 Fibronectin binding domains with reduced immunogenicity
Fibronectin type III (10Fn3) binding domains having novel designs that are associated with reduced immunogenicity are provided. The application describes...
US-9,522,950 Oxidant resistant apolipoprotein A-1 and mimetic peptides
A purified polypeptide includes an ApoA1 mimetic or fragment thereof that are resistant to oxidation.
US-9,522,949 Fusion protein for antagonizing angiogenesis inducible factors and uses thereof
The present invention relates to angiogenesis-inhibitory fusion proteins and use thereof. Particularly, the present invention provides fusion proteins...
US-9,522,948 GP100-specific T cell receptors and related materials and methods of use
The invention provides human cells, particularly human T cells, comprising a murine T Cell Receptor (TCR) having antigen specificity for the cancer antigen...
US-9,522,947 Peptidomimetic macrocycles
The present invention provides peptidomimetic macrocycles capable of modulating growth hormone levels and methods of using such macrocycles for the treatment of...
US-9,522,946 Oxyntomodulin derivatives and pharmaceutical composition for treating obesity comprising the same
The present invention relates to a novel peptide showing more excellent activities on a glucagon like peptide-1 receptor and a glucagon receptor than native...
US-9,522,945 Long-acting oxyntomodulin variants and methods of producing same
This invention is directed to a chorionic gonadotrophin carboxy terminal peptide (CTP) modified dual GLP-1/glucagon receptor agonist, and methods of producing...
US-9,522,944 Peptides of syndecan-1 for inhibit angiogenesis
The present invention provides a peptide derived from the extracellular domain of syndecan-1 that inhibits angiogenesis.
US-9,522,943 Treating human immunodeficiency virus infections
Methods and compositions for determining a prognosis for a subject infected with HIV, reducing a risk of an HIV infection, and treating or reducing a risk of...
US-9,522,942 Analogs of temporin-SHa and uses thereof
The present invention relates to novel antimicrobial peptides, to pharmaceutical compositions comprising said peptides, and to the uses thereof, in particular...
US-9,522,941 Methods and compositions related to chromatin-associated proteins and other factors
Chromatin-associated proteins and other factors and their related methods and compositions are isolated and identified.
US-9,522,940 Lipocalin muteins with binding-affinity for glypican-3 (GPC-3) and use of lipocalin muteins for target-specific...
The present invention relates to novel, specific-binding therapeutic and/or diagnostic lipocalin muteins directed against Glypican-3 (GPC-3). The invention also...
US-9,522,939 Hypoallergenic chimeric proteins belonging to the lipid transfer family of Parietaria judaica for use in the...
The present invention relates to recombinant DNA molecules which encode chimeric polypeptides of differing allergens of Parietaria judaica which can be used for...
US-9,522,938 Phl p 5a derivatives having reduced allergeneity and retained T-cell reactivity
The present invention relates to the preparation and use of variants of the group 5 allergen of the Pooideae which are characterised by reduced IgE reactivity...
US-9,522,937 Insecticidal proteins
Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at...
US-9,522,936 Engineered transcription activator like effector (TALE) proteins
Disclosed herein are methods and compositions for design and use of engineered TALEs.
US-9,522,935 Commands and method of treating cancer via RHO pathway
Lanosterol derivatives useful as anti-cancer agent, which can inhibit the growth of lung cancer cells, liver cancer cells, mammary cancer cells, brain cancer...
US-9,522,934 Acetatic abiraterone trifluoroacetate and preparation method and application of same
Provided are acetaic abiraterone trifluoroacetate, a preparation method and an application of same. The acetaic abiraterone trifluoroacetate is obtained through...
US-9,522,933 Diagnosis of hereditary spastic paraplegias (HSP) by identification of a mutation in the ZFYVE26 gene or protein
The Invention relates to an ex vivo method of diagnosing or predicting a hereditary spastic paraplegias (HSP), in a subject, which method comprises detecting a...
US-9,522,932 Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral...
The invention is directed to a process for the preparation of substituted threonolactone and substituted threose compounds which are intermediates in the...
US-9,522,931 Process for the preparation of compounds useful as inhibitors of SGLT-2
The present invention is directed to a novel process for the preparation of compounds having inhibitory activity against sodium-dependent glucose transporter...
US-9,522,930 Chartreusin analogues
The present invention relates to novel Chartreusin analogues of formula (I), pharmaceutical compositions comprising the same and to their use for the treatment...
US-9,522,929 Non-caloric sweetener
Disclosed is a steviol glycoside referred to as rebaudioside D3. Rebaudioside D3 has five .beta.-D-glucosyl units connected to the aglycone steviol. Also...
US-9,522,928 Mannosylated compounds useful for the prevention and the treatment of infectious diseases
The present invention relates to new anti-infectious compounds consisting of (i) a polar head having from one to three mannose, dimannose or trimannose...
US-9,522,927 DOPO derivative flame retardants
The present invention relates to novel, halogen-free flame retardant derived from 9,10-Dihydro-9-Oxa-10-Phosphaphenantrene-10-oxide (DOPO). This invention also...
US-9,522,926 Activators of glucokinase
The present invention provides for novel compounds of Formulas I and II and pharmaceutically acceptable salts and co-crystals thereof which have glucokinsae...
US-9,522,925 Selective cancer tracking eradicator and the uses thereof
The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional--PDT and...
US-9,522,924 Pyridone derivatives as acid secretion inhibitors and process for preparation thereof
The present invention relates to the preparation of stable pyridone disulphide derivatives having general formula (I) and its stereoisomers, which are useful in...
US-9,522,923 Selective BACE1 inhibitors
The present invention provides a compound of Formula II: ##STR00001## or a pharmaceutically acceptable salt thereof, that are inhibitors of BACE.
US-9,522,922 Process for the preparation of intermediate for the preparation of oseltamivir phosphate
The present invention discloses an economic, simple, azide and aziridine complexity free process for the synthesis of osletamivir phosphate (Tamiflu) by...
US-9,522,921 Photochromic spirooxazine compounds
A photochromic dye comprising at least one compound characterized by Formula I: ##STR00001##
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