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Jucara and Acai fruit-based compositions
The present invention relates to stable, palatable, freeze-dried, fruit-based compositions. Specifically, the inventions relates to compositions of Acai fruit...
Plant polyphenols extraction and activation thereof
Combinations of dried plants can be prepared to form a herbal medicine, including reacting, in hydrogen peroxide, a combination of the extraction of pomegranate...
Preparation comprising amino acids and plants and its activity in the
The invention relates to a preparation containing several amino acids and plant extracts and its alcohol detoxification activity. The component (a) in the...
Composition of cannabinoids, odorous volatile compounds, and emu oil for
topical application, and a method for...
A composition of cannabinoids, odorous volatile compounds, and emu oil for topical application, and a method for cannabinoid transdermal delivery wherein said...
A dietary supplement comprising powdered ingredients: zeolite powder: 70%-5%, dehydrated seaweed: 5%-25%, seawater extract: 5%-10% Chlorella: 5%-10% and...
Induction of mucosal tolerance to antigens
The present invention relates to the induction of tolerance to antigens, by mucosal, preferably oral delivery of the antigen in combination with an...
Methods of isolating distinct pancreatic cell types
Methods of isolating distinct specific cell types within mixed populations of cells. Methods of isolating specific cell types among pancreatic cells,...
Human skin equivalents expressing exogenous polypeptides
The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered...
Use of multipotent adult stem cells in treatment of myocardial infarction
and congestive heart failure
The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form...
Wound healing composition
The present invention relates to compositions and methods for tissue regeneration, particularly for treating skin lesions such as wounds. In one aspect, the...
Silver nanoplate compositions and methods
Embodiments of the present invention relate to methods for preparing high optical density solutions of nanoparticle, such as nanoplates, silver nanoplates or...
Method for producing NO/N.sub.2 gaseous mixtures intended for the medical
The invention relates to a method for producing an NO/N.sub.2 gaseous mixture, comprising the steps of effecting a purification of impure gaseous nitrogen...
Non-digestible sugar-coated products and process
A method and composition are provided for coating a component to achieve colon-targeted delivery. A component is coated with a fructose-based non-digestible...
Use of epigenome-modifying compounds for the treatment of genetic muscular
diseases linked to a...
A pharmaceutical composition including at least one epigenome-modifying compound, for a use thereof in the treatment of genetic muscular diseases linked to a...
Chemosensory receptor ligand-based therapies
Provided herein are methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions comprising chemosensory receptor ligands. Also...
Prochelators as broad-spectrum antimicrobial agents and methods of use
The present disclosure provides methods of treating (including ameliorating and/or preventing) pathogenic infections by administering a therapeutically...
Compositions and methods to treat cardiac diseases
Phosphonate and phosphinate N-methanocarba derivatives of AMP including their prodrug analogs are described. MRS2339, a 2-chloro-AMP derivative containing a...
Topical gels and methods of using the same
Provided according to some embodiments of the invention are topical gels that may release nitric oxide. Also provided are methods of using such topical gels in...
Oxysterols for activation of hedgehog signaling, osteoinduction,
antiadipogenesis, and Wnt signaling
Synthetic oxysterols can be made and can be used for the treatment of bone disorders, obesity, cardiovascular disorders, and neurological disorders.
Transdermal therapeutic system comprising norelgestromin for contraception
and hormone replacement
The present invention relates to a transdermal therapeutic system for applying the active ingredient norelgestromin onto the skin, optionally in combination...
Method for suppressing surgical site infection and column to be used for
An object of the present invention is to provide a method for suppressing surgical site infections (SSI) that have occurred at extremely high incidence rates at...
Formulation of meloxicam
Unit dosage forms of meloxicam containing either 5 mg or 10 mg of meloxicam that provide effective pain relief and have desirable pharmacokinetic properties are...
The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the...
Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the
treatment of chemokine-mediated...
Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds represented by the general formula (I) are described. Also described, are pharmaceutical...
Method of inhibiting C-KIT kinase
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell...
Use of a DPP-4 inhibitor in podocytes related disorders and/or nephrotic
The present invention relates to methods for treating and/or preventing podocytes related disorders and/or nephrotic syndrome comprising the administration of...
Medicament for treating peripheral neuropathies
The invention provides a method for treatment of the diseases in a human by identifying the human as one suffering from a herpes simplex virus (HSV), and then...
Medical use of a DPP-4 inhibitor
The present invention relates to the use of 1-[(4-methyl-quinazolin-2-yl)methyl]-3 -methyl-7-(2-butyn-1-yl)-8-(3-(R)-amino-piperidin-1-yl)-xanthine for use ...
Inhibitors of beta-secretase
The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the.beta.-secretase enzyme (BACE1) activity, pharmaceutical...
Aripiprazole formulations having increased injection speeds
The present invention relates to pharmaceutical compositions comprising a compound of Formula (I) that are useful for the intramuscular delivery of ...
Selective histamine H4 receptor antagonists for the treatment of
The invention relates to Histamine H4 receptor antagonists or inhibitors of Histamine H4 receptor gene expression for the treatment and/or the prevention of...
Controlled release hydrocodone formulations
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a...
Treatment with opioid antagonists and mTOR inhibitors
Embodiments of the invention provide methods of treating a disorder or disease characterized by cellular proliferation and migration by co-administering a...
Oncogenic ROS1 kinase inhibitor
The present invention provides a compound that inhibits activity of oncogenic ROS1, a composition comprising said compound. The present invention also provides...
Tetrahydroprotoberbine compounds and uses thereof in the treatment of
neurological, psychiatric and...
Tetrahydroprotoberbine (THPB) compounds and their use in the treatment of neurological, psychiatric and neurodegenerative diseases is provided. The compounds...
Modulators of hepatic lipoprotein metabolism
The present invention relates to compounds that are useful for modulating hepatic cholesterol metabolism in an animal. The invention includes methods of making...
Tetrahydroisoquinolin-1-one derivative or salt thereof
To provide a pharmaceutical, in particular a compound which can be used as a therapeutic agent for irritable bowel syndrome (IBS). It was found that a...
Combination of effective substances causing synergistic effects of
multiple targeting and use thereof
Disclosed are a combination of active components inducing synergistic effects of multi-targeting and a use thereof. More particularly, disclosed are a...
Composition for treating immune diseases containing daurinol compound as
The daurinol compound according to the present invention exhibits excellent therapeutic effects on arthritis and inflammatory bowel diseases by having an...
Compositions for the treatment of peripheral ulcers of various origins
The present invention relates to combinations of an agent that stimulates cell proliferation and an anti-inflammatory/analgesic, which are useful in the...
Chemical engineering processes and apparatus for the synthesis of
The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive...
Method for treating skin lesions with ingenol mebutate
The invention provides novel methods for topical treatment of skin lesions such as actinic keratosis over treatment areas up to 250 cm.sup.2.
Use of dencichine in preparation of drug for treating thrombocytopenia
Disclosed are uses of drugs for treating thrombocytopenia, in particular the use of dencichine in preparation of drugs for treating thrombocytopenia. By adding...
Methods and agents for preventing and treating plasma cell dyscrasias
Screening assays and methods of using same for screening to identify modulator agents or compounds that target endoplasmic reticulum stress related signaling...
Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor
The present invention relates to new biphenyl-3-carboxylic acid modulators of beta-3-adrenoceptor activity, pharmaceutical compositions thereof, and methods of...
Treatment and diagnosis of melanoma
The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.
Compositions and methods for treating cancer
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
Methods for prostatectomy
A method of reducing nerve damage associated with prostatectomy in a human subject includes the steps of infiltrating a phenylephrine containing solution into...
Methods for treating or preventing neuroinflammation or autoimmune
Disclosed herein are ribonucleotide reductase inhibitors, compositions comprising ribonucleotide reductase inhibitors, and methods for treating and/or...
Method of using dihydro-resveratrol for treating acute pancreatitis and
associated pulmonary injury
The present invention relates to a method of using trans-3,5,4'-trihydroxybibenzyl, also known as dihydro-resveratrol for treating acute pancreatitis in a...