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Method for separation of chemically pure Os from metal mixtures
A method for separating an amount of osmium from a mixture containing the osmium and at least one other additional metal is provided. In particular, method for...
Nano wire and method for manufacturing the same
A method for manufacturing a nanowire is provided. A solvent is heated. A catalyst is added to the solvent. A metal compound is added to the solvent to form a...
Ultrasonic probes with gas outlets for degassing of molten metals
Ultrasonic probes containing a plurality of gas delivery channels are described, as well as ultrasonic probes containing recessed areas near the tip of the...
Closed transport fluid system for furnace-internal heat exchange between
A furnace for heat treating an annealing material. A sealable first furnace chamber is designed to receiving and heat treating annealing material. A first heat...
Apparatus for the continuous thermal treatment of electrically conductive
continually cast material and...
In an apparatus for the continuous thermal treatment of metal continuously cast material having a heating section, the metal continuously cast material having a...
Sugar recovery method from ligno-cellulosic biomass
Disclosed in this specification is a process for the improved hydrolysis of glucans to glucose wherein a portion of the glucose is removed from the process to...
Reagents and methods for detecting HCV
The present disclosure relates to oligonucleotide sequences for amplification primers and their use in performing nucleic acid amplifications of HCV, in...
Sequences and their use for detection and characterization of STEC
This invention relates to a rapid method for detection and characterization of STEC bacteria based on the presence of nucleic acid sequences, in particular, to...
Materials and methods for quality-controlled two-color RT-QPCR diagnostic
testing of formalin fixed embedded...
Described herein are materials, methods, and kits enabling accurate and reproducible two-color reverse-transcription real-time quantitative PCR (RT-qPCR) for...
Rare clonotypes and uses thereof
The invention is directed to a method of selecting disease-correlated clonotypes that have a reduced likelihood of producing a false positive signal of relapse...
Method for improved diagnosis of dysplasias
The present invention relates to a method for improved diagnosis of dysplasias based on simultaneous detection of INK4a gene products and at least one marker...
miRNA fingerprint in the diagnosis of COPD
MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play...
Methods, compositions, and kits for determing the presence/absence of a
variant nucleic acid sequence
The present invention provides methods, compositions and kits for detecting the presence, absence or amount of a target nucleic acid or at least one variant...
Method for determining the predisposition of a patient to changed
biotransformation and to the development of...
A method for determining a predisposition of a patient to the development of muscular diseases and/or to changed biotransformation in a treatment of the patient...
In vitro method for determining immunotoxicity of a compound
The invention is in the field of molecular diagnostics. More in particular it provides marker genes for determining the immunotoxicity of compounds. A method...
Methods and compositions for identifying undifferentiated stem cells and
assessing cell health
Disclosed herein are methods and compositions for the identification of teloRNA marks to assess the differentiation status of an individual stem cell or a...
Base-by-base ratcheting of DNA/RNA in a Y-shaped nanochannel
A mechanism is provided for ratcheting a double strand molecule. The double strand molecule is driven into a Y-channel of a membrane by a first voltage pulse....
DNA sequencing methods and detectors and systems for carrying out the same
In some embodiments, an analyte detection system is provided that includes a nanochannel, an electrode arrangement, and a plurality of nanoFET devices disposed...
Four-color DNA sequencing by synthesis using cleavable fluorescent
nucleotide reversible terminators
This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.
Method for analyzing multiple nucleic acid targets
A detection device includes a PCR processor for conducting a PCR process on a first drop to a fourth drop flowing in a flow channel, a boundary detector for...
Multiplex targeted amplification using flap nuclease
Methods for multiplex amplification of a plurality of targets of distinct sequence from a complex mixture are disclosed. In one aspect targets are circularized...
Sequence amplification with loopable primers
The present disclosure relates to the amplification of target nucleic acid sequences. This can be accomplished via the use of various primers. The use of these...
Processes for detecting or quantifying more than one nucleic acid in a
This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes...
Rare earth spatial/spectral barcodes for multiplexed biochemical testing
Hydrogel microparticles spatially and spectrally encoded using upconverting phosphor nanoparticles are described for use in biochemical testing. In each...
Rare earth spatial/spectral microparticle barcodes for labeling of objects
Polymer microparticles spatially and spectrally encoded using upconversion nanocrystals (UCN) are described for labeling of articles and tissues. UCN having...
Tracer reagents that enhance reaction-product analysis
A composition suitable for formulation of an enzymatic reaction mixture, the composition comprising a reaction component essential for an ex-vivo non-polymerase...
Heat-reduction methods and systems related to microfluidic devices
Systems and methods for preventing or reducing unwanted heat in a microfluidic device while generating heat in selected regions of the device are described....
Nuclear localization of Src-family tyrosine kinases is required for growth
A method for quantitatively evaluating chromatin structural changes using pixel imaging of the nucleus is provided. Pixel imaging of the nucleus can include...
Biocompatible method of functionalizing substrates with inert surfaces
Method of functionalizing microspheres comprising immersing the microspheres in an aqueous dispersion of a construct of the structure F-S-L; and then washing...
Method for discovering algal strains with reduced pigment to attain higher
A method for determining and/or engineering photosynthetic mutant algal strains comprising: (A) pre-screening wild-type or parent strains to select for...
Methods for cell-free protein synthesis
Cell-free protein synthesis systems and methods of using the same for producing in vitro protein materials in high yield are disclosed. The cell-free protein...
Methods of modifying eukaryotic cells
A method for engineering and utilizing large DNA vectors to target, via homologous recombination, and modify, in any desirable fashion, endogenous genes and...
Method and apparatus for cooling pretreated biomass prior to mixing with
A method to treat biomass, e.g., lignocellulosic material, including: performing a pretreatment step on the biomass and discharging the pretreated biomass; in...
Branched .alpha.-glucan, .alpha.-glucosyltransferase which forms the
glucan, their preparation and uses
The present invention has objects to provide a glucan useful as water-soluble dietary fiber, its preparation and uses. The present invention solves the above...
Compositions and methods for producing chemicals and derivatives thereof
The present invention provides methods for producing a product of one or more enzymatic pathways. The pathways used in the methods of the invention involve one...
Recombinant cellulosome complex and uses thereof
The present invention relates to a polynucleotide encoding a recombinant scaffolding polypeptide comprising at least a signal peptide, a Cellulose Binding...
Methods of using ketoreductase polypeptides for reduction of acetophenones
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme....
Processes and control systems for high efficiency anaerobic conversion of
hydrogen and carbon oxides to alcohols
High conversion efficiency processes are disclosed for the anaerobic bioconversion of syngas to alcohol. The processes use bioreactors that have a non-uniform...
Pre-treatment of cellulosic material
A method of pre-treating a cellulosic material before hydrolysis is provided. The method comprises the steps of: impregnating the cellulosic material with a...
Method for the simultaneous production of ethanol and a fermented, solid
The invention relates to a method for the simultaneous production of a fermented, solid product and ethanol comprising the following steps: 1) providing a...
Recombinant synthesis of medium chain-length alkanes
The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently produce...
Methods for producing preparations of recombinant AAV virions
substantially free of empty capsids
Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography...
Mammalian expression vector pUHAB
The present invention relates to the construction and utilization of a new mammalian expression vector that contains a unique multiple cloning site (MCS),...
Efficient non-meiotic allele introgression
Methods, uses, and animals for introgression of alleles between animals, including SNPs. One embodiment involves introducing a targeted targeting endonuclease...
dsRNA as insect control agent
The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for making...
Axmi270 toxin gene and methods of use
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding...
This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell...
Artificial plant promoter activated by broad spectrum of xanthomonas
The present invention relates to synthetic promoter and a synthetic gene which confers broad-spectrum disease resistance to Xanthomonands in plants. The present...
Transgenic cells with increased plastoquinone levels and methods of use
Disclosed herein are transgenic cells expressing a heterologous nucleic acid encoding a prephenate dehydrogenase (PDH) protein, a heterologous nucleic acid...
Heavy metal reduction in planta
There is described a mutant, non-naturally occurring or transgenic plant or plant cell comprising (a) a polynucleotide selected from the group consisting of:...