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Patent # | Description |
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US-9,533,058 |
Carrier-antibody compositions and methods of making and using the same Described herein are compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. Also... |
US-9,533,057 |
Immunogenic HPV L2-containing VLPs and related compositions, constructs,
and therapeutic methods The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of human... |
US-9,533,056 |
Dipeptide-based prodrug linkers for aliphatic amine-containing drugs The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof, comprising a drug linker conjugate D-L, wherein D being a biologically... |
US-9,533,055 |
Compositions and methods for blood-brain barrier delivery of IgG-decoy
receptor fusion proteins Provided herein are compositions and related methods for delivering an IgG-decoy receptor to the CNS. The methods include systemic administration of a... |
US-9,533,054 |
Amphiphilic drug-drug conjugates for cancer therapy, compositions and
methods of preparation and uses thereof The invention provides novel amphiphilic drug-drug conjugates useful as cancer therapeutics, and compositions and methods thereof. |
US-9,533,053 |
High concentration olopatadine ophthalmic composition The present invention is an ophthalmic composition containing a relatively high concentration of olopatadine. The composition is typically an ophthalmic aqueous... |
US-9,533,052 |
Aqueous ophthalmic suspension of crystalline rebamipide The invention provides an ophthalmic product containing rebamipide, which has a transparency enough to be agreeable feeling on using it and has neutral so... |
US-9,533,051 |
Menthol-based nanoparticles for drug delivery The subject invention pertains to formulations comprising poly(menthyl acrylate) nanoparticles comprising at least one active ingredient contained in a... |
US-9,533,050 |
Vaginal ring including meloxicam and an agent for modulating the release
of the active principle, which can be... The invention relates to a sustained-release vaginal ring which includes meloxicam and an agent for modulating the release of the active principle, such as... |
US-9,533,049 |
Method for preparing nanoparticles based on functional amphiphilic
molecules or macromolecules, and the use thereof The invention relates to a method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, optionally in the presence of at... |
US-9,533,048 |
Mucosal delivery of drugs The present invention provides a composition comprising or consisting of components (a) (i) at least one mono-alkanoyl glycerol ester, wherein alkanoyl is... |
US-9,533,047 |
Delivery and formulation of engineered nucleic acids Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression.... |
US-9,533,046 |
Controlled release formulations of levodopa and uses thereof The current invention provides a controlled release oral solid formulation of levodopa comprising levodopa, a decarboxylase inhibitor, and a carboxylic acid.... |
US-9,533,045 |
Photothermal therapy using magnetic nanoparticles The present invention provides methods, systems, and devices for performing photothermal therapy (e.g., to treat cancer) using photothermal nanoparticles with a... |
US-9,533,044 |
Methods of treating inflammatory disorders using high concentration
natalizumab compositions Formulations of VLA-4 binding antibody are described. |
US-9,533,043 |
Identification of surface-associated antigens for tumor diagnosis and
therapy An isolated truncated desmoglein 4 (DSG4) polypeptide splice variant of the invention is characterized by an amino acid sequence that lacks a region encoded... |
US-9,533,042 |
Anti-notch NRR antibodies and methods using same The invention provides anti-Notch1 NRR antibodies, and compositions comprising and methods of using these antibodies. |
US-9,533,041 |
Methods for the treatment of heart failure The present invention relates to an inhibitor of NGAL gene expression or a NGAL antagonist for use in the prevention or the treatment of heart failure. |
US-9,533,040 |
Inhibition of human immunodeficiency virus integrase reaching dimer
formation utilizing single-chain variable... Methods to inhibit the formation of retrovirus integrase reaching dimers, to dissociate retrovirus integrase reaching dimers, and to stabilize retrovirus... |
US-9,533,039 |
Methods of treating systemic lupus erythematosus (SLE) using anti-CD48
antibodies The present invention provides antibodies that bind to CD48 and methods of using same. According to certain embodiments of the invention, the antibodies are... |
US-9,533,038 |
Soluble forms of hendra and nipah virus G glycoprotein This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble... |
US-9,533,037 |
Methods for designing and preparing vaccines comprising directed sequence
polymer compositions via the directed... The instant invention comprises a process of preparing a composition comprising directed sequence polymer (DSP) mixtures that act as epitopes and useful as... |
US-9,533,036 |
Methods for generating immune responses to influenza antigens with a
secretable CD40L fusion protein Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the... |
US-9,533,035 |
Truncated L1 protein of human papillomavirus type 11 The invention relates to a truncated L1 protein of the Human Papillomavirus Type 11, a virus-like particle consisting of the protein, a vaccine comprising said... |
US-9,533,034 |
Vaccine for intrauterine disease Provided are compositions and methods for use in prophylaxis of puerperal metritis and improving reproductive function of ruminants. The methods and... |
US-9,533,033 |
Haemophilus influenzae type IV pili The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type... |
US-9,533,032 |
Protein matrix vaccines and related methods of making and administering
such vaccines The invention relates to vaccine compositions having a carrier protein and an antigen of interest entrapped in a complex, methods of making such vaccines, and... |
US-9,533,031 |
Yeast-MUC1 immunotherapeutic compositions and uses thereof Disclosed are yeast-based immunotherapeutic compositions comprising mucin-1 (MUC1), as well as methods for the prevention and/or treatment of cancers... |
US-9,533,030 |
Vaccine capable of inducing formation of antibodies directed to proprotein
convertase subtilisin/kexin type 9... The present invention relates to a vaccine capable to induce the formation of antibodies directed to PCSK9 in vivo. |
US-9,533,029 |
Method of treating depression Methods are disclosed herein for treating depression in the subject. A method includes the use of Botulinum toxin to cause paralysis of a facial muscle, such as... |
US-9,533,028 |
Complement factor B analogs and their uses The invention provides polypeptides comprising a complement factor B analog. The invention also provides various complement factor B analogs including... |
US-9,533,027 |
Biodegradable nanoparticles as novel hemoglobin-based oxygen carriers and
methods of using the same Compositions of matter and methods for making, storing and administering artificial blood substitutes. Artificial blood substitutes may have oxygen carriers... |
US-9,533,026 |
Polypeptide compounds for inhibiting angiogenesis and tumor growth In certain embodiments, this present invention provides polypeptide compositions, including compositions containing a modified polypeptide, and methods for... |
US-9,533,025 |
Method for treating chemotherapy-induced male infertility A method of ameliorating, inhibiting, preventing, or reducing male infertility in a subject undergoing or in need of chemotherapy by administering to the... |
US-9,533,024 |
Methods and compositions for repair of cartilage using an in vivo
bioreactor Methods and compositions for the biological repair of cartilage using a hybrid construct combining both an inert structure and living core are described. The... |
US-9,533,023 |
EIF4E binding peptides The present invention relates to modified eIF4G1 peptides, uses thereof and pharmaceutical compositions comprising the modified eIF4G1 peptides. |
US-9,533,022 |
Peptide analogs for treating diseases and disorders Provided herein are methods for the treatment of type I diabetes, Type II diabetes, metabolic syndrome, or obesity, or of appetite suppression, or for... |
US-9,533,021 |
Nutritional supplement A nutritional supplement for inhibiting sensorineural hearing loss includes from about 0.25 to about 6.0 wt. % thiamin, from about 0.1 to about 10 wt. %... |
US-9,533,020 |
Pharmaceutical compositions for treating thermal injuries and wounds
combined with bone injuries The present invention relates to a pharmaceutical composition for treating thermal injuries and wounds combined with bone injuries. More specifically, the... |
US-9,533,019 |
Calotropis procera extracts as anti-ulcerative colitis agents The Calotropis Procera extracts as anti-ulcerative colitis agents include extracts of Calotropis procera obtained by a method comprising the following steps:... |
US-9,533,018 |
Method of processing Antrodia cinnamomea The invention discloses a method of processing Antrodia cinnamomea for producing a processed sample of Antrodia cinnamomea, which easily releases antcin K in a... |
US-9,533,017 |
Saccharomyces cerevisiae yeast for preventing and/or treating vaginal
mycoses The present invention relates to the Saccharomyces Cerevisiae strain deposited with the French National Collection of Micro-organism Cultures under number CNCM... |
US-9,533,016 |
Lactococcus lactis strains New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides... |
US-9,533,015 |
Lactococcus lactis strains New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides... |
US-9,533,014 |
Synergistic bacterial compositions and methods of production and use
thereof Provided are therapeutic compositions containing Ecobiotic.TM. populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a... |
US-9,533,013 |
Method of treating pancreatic and liver conditions by endoscopic-mediated
(or laparoscopic-mediated)... A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor... |
US-9,533,012 |
Method for enhancing therapeutic effect of stem cells A method for enhancing the therapeutic effect of a stem cell is provided. The method comprises treating the stem cell with ligustilide, wherein the treatment is... |
US-9,533,011 |
Placental tissue grafts and methods of preparing and using the same Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been... |
US-9,533,010 |
Compositions and methods for treating progressive myocardial injury due to
a vascular insufficiency The described invention provides methods and regimens for treating adverse consequences of a persistent and progressive myocardial injury-due to a vascular... |
US-9,533,009 |
Producing human CD34+CD7+CD5+CD1a- progenitor T cells and method of
treatment Human progenitor T cells that are able to successfully engraft a murine thymus and differentiate into mature human T and NK cells are described. The human... |