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Patent # Description
US-9,533,058 Carrier-antibody compositions and methods of making and using the same
Described herein are compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. Also...
US-9,533,057 Immunogenic HPV L2-containing VLPs and related compositions, constructs, and therapeutic methods
The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of human...
US-9,533,056 Dipeptide-based prodrug linkers for aliphatic amine-containing drugs
The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof, comprising a drug linker conjugate D-L, wherein D being a biologically...
US-9,533,055 Compositions and methods for blood-brain barrier delivery of IgG-decoy receptor fusion proteins
Provided herein are compositions and related methods for delivering an IgG-decoy receptor to the CNS. The methods include systemic administration of a...
US-9,533,054 Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof
The invention provides novel amphiphilic drug-drug conjugates useful as cancer therapeutics, and compositions and methods thereof.
US-9,533,053 High concentration olopatadine ophthalmic composition
The present invention is an ophthalmic composition containing a relatively high concentration of olopatadine. The composition is typically an ophthalmic aqueous...
US-9,533,052 Aqueous ophthalmic suspension of crystalline rebamipide
The invention provides an ophthalmic product containing rebamipide, which has a transparency enough to be agreeable feeling on using it and has neutral so...
US-9,533,051 Menthol-based nanoparticles for drug delivery
The subject invention pertains to formulations comprising poly(menthyl acrylate) nanoparticles comprising at least one active ingredient contained in a...
US-9,533,050 Vaginal ring including meloxicam and an agent for modulating the release of the active principle, which can be...
The invention relates to a sustained-release vaginal ring which includes meloxicam and an agent for modulating the release of the active principle, such as...
US-9,533,049 Method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, and the use thereof
The invention relates to a method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, optionally in the presence of at...
US-9,533,048 Mucosal delivery of drugs
The present invention provides a composition comprising or consisting of components (a) (i) at least one mono-alkanoyl glycerol ester, wherein alkanoyl is...
US-9,533,047 Delivery and formulation of engineered nucleic acids
Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression....
US-9,533,046 Controlled release formulations of levodopa and uses thereof
The current invention provides a controlled release oral solid formulation of levodopa comprising levodopa, a decarboxylase inhibitor, and a carboxylic acid....
US-9,533,045 Photothermal therapy using magnetic nanoparticles
The present invention provides methods, systems, and devices for performing photothermal therapy (e.g., to treat cancer) using photothermal nanoparticles with a...
US-9,533,044 Methods of treating inflammatory disorders using high concentration natalizumab compositions
Formulations of VLA-4 binding antibody are described.
US-9,533,043 Identification of surface-associated antigens for tumor diagnosis and therapy
An isolated truncated desmoglein 4 (DSG4) polypeptide splice variant of the invention is characterized by an amino acid sequence that lacks a region encoded...
US-9,533,042 Anti-notch NRR antibodies and methods using same
The invention provides anti-Notch1 NRR antibodies, and compositions comprising and methods of using these antibodies.
US-9,533,041 Methods for the treatment of heart failure
The present invention relates to an inhibitor of NGAL gene expression or a NGAL antagonist for use in the prevention or the treatment of heart failure.
US-9,533,040 Inhibition of human immunodeficiency virus integrase reaching dimer formation utilizing single-chain variable...
Methods to inhibit the formation of retrovirus integrase reaching dimers, to dissociate retrovirus integrase reaching dimers, and to stabilize retrovirus...
US-9,533,039 Methods of treating systemic lupus erythematosus (SLE) using anti-CD48 antibodies
The present invention provides antibodies that bind to CD48 and methods of using same. According to certain embodiments of the invention, the antibodies are...
US-9,533,038 Soluble forms of hendra and nipah virus G glycoprotein
This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble...
US-9,533,037 Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed...
The instant invention comprises a process of preparing a composition comprising directed sequence polymer (DSP) mixtures that act as epitopes and useful as...
US-9,533,036 Methods for generating immune responses to influenza antigens with a secretable CD40L fusion protein
Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the...
US-9,533,035 Truncated L1 protein of human papillomavirus type 11
The invention relates to a truncated L1 protein of the Human Papillomavirus Type 11, a virus-like particle consisting of the protein, a vaccine comprising said...
US-9,533,034 Vaccine for intrauterine disease
Provided are compositions and methods for use in prophylaxis of puerperal metritis and improving reproductive function of ruminants. The methods and...
US-9,533,033 Haemophilus influenzae type IV pili
The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type...
US-9,533,032 Protein matrix vaccines and related methods of making and administering such vaccines
The invention relates to vaccine compositions having a carrier protein and an antigen of interest entrapped in a complex, methods of making such vaccines, and...
US-9,533,031 Yeast-MUC1 immunotherapeutic compositions and uses thereof
Disclosed are yeast-based immunotherapeutic compositions comprising mucin-1 (MUC1), as well as methods for the prevention and/or treatment of cancers...
US-9,533,030 Vaccine capable of inducing formation of antibodies directed to proprotein convertase subtilisin/kexin type 9...
The present invention relates to a vaccine capable to induce the formation of antibodies directed to PCSK9 in vivo.
US-9,533,029 Method of treating depression
Methods are disclosed herein for treating depression in the subject. A method includes the use of Botulinum toxin to cause paralysis of a facial muscle, such as...
US-9,533,028 Complement factor B analogs and their uses
The invention provides polypeptides comprising a complement factor B analog. The invention also provides various complement factor B analogs including...
US-9,533,027 Biodegradable nanoparticles as novel hemoglobin-based oxygen carriers and methods of using the same
Compositions of matter and methods for making, storing and administering artificial blood substitutes. Artificial blood substitutes may have oxygen carriers...
US-9,533,026 Polypeptide compounds for inhibiting angiogenesis and tumor growth
In certain embodiments, this present invention provides polypeptide compositions, including compositions containing a modified polypeptide, and methods for...
US-9,533,025 Method for treating chemotherapy-induced male infertility
A method of ameliorating, inhibiting, preventing, or reducing male infertility in a subject undergoing or in need of chemotherapy by administering to the...
US-9,533,024 Methods and compositions for repair of cartilage using an in vivo bioreactor
Methods and compositions for the biological repair of cartilage using a hybrid construct combining both an inert structure and living core are described. The...
US-9,533,023 EIF4E binding peptides
The present invention relates to modified eIF4G1 peptides, uses thereof and pharmaceutical compositions comprising the modified eIF4G1 peptides.
US-9,533,022 Peptide analogs for treating diseases and disorders
Provided herein are methods for the treatment of type I diabetes, Type II diabetes, metabolic syndrome, or obesity, or of appetite suppression, or for...
US-9,533,021 Nutritional supplement
A nutritional supplement for inhibiting sensorineural hearing loss includes from about 0.25 to about 6.0 wt. % thiamin, from about 0.1 to about 10 wt. %...
US-9,533,020 Pharmaceutical compositions for treating thermal injuries and wounds combined with bone injuries
The present invention relates to a pharmaceutical composition for treating thermal injuries and wounds combined with bone injuries. More specifically, the...
US-9,533,019 Calotropis procera extracts as anti-ulcerative colitis agents
The Calotropis Procera extracts as anti-ulcerative colitis agents include extracts of Calotropis procera obtained by a method comprising the following steps:...
US-9,533,018 Method of processing Antrodia cinnamomea
The invention discloses a method of processing Antrodia cinnamomea for producing a processed sample of Antrodia cinnamomea, which easily releases antcin K in a...
US-9,533,017 Saccharomyces cerevisiae yeast for preventing and/or treating vaginal mycoses
The present invention relates to the Saccharomyces Cerevisiae strain deposited with the French National Collection of Micro-organism Cultures under number CNCM...
US-9,533,016 Lactococcus lactis strains
New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides...
US-9,533,015 Lactococcus lactis strains
New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides...
US-9,533,014 Synergistic bacterial compositions and methods of production and use thereof
Provided are therapeutic compositions containing Ecobiotic.TM. populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a...
US-9,533,013 Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated)...
A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor...
US-9,533,012 Method for enhancing therapeutic effect of stem cells
A method for enhancing the therapeutic effect of a stem cell is provided. The method comprises treating the stem cell with ligustilide, wherein the treatment is...
US-9,533,011 Placental tissue grafts and methods of preparing and using the same
Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been...
US-9,533,010 Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
The described invention provides methods and regimens for treating adverse consequences of a persistent and progressive myocardial injury-due to a vascular...
US-9,533,009 Producing human CD34+CD7+CD5+CD1a- progenitor T cells and method of treatment
Human progenitor T cells that are able to successfully engraft a murine thymus and differentiate into mature human T and NK cells are described. The human...
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