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Methods and compositions for enhancing an immune response, blocking
monocyte migration, amplifying vaccine...
Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an...
Recombinant bacterium and uses thereof
The present invention relates to a recombinant bacterium expressing an antigen that is translocated to the cytosol of a host organism, and uses thereof. To this...
Nasal vaccine against the development of atherosclerosis disease and fatty
The present invention provides a novel vaccine compound of micellar nanoparticles to be administered intranasally to treat and/or prevent the disease called...
Lipase variants for pharmaceutical use
The pharmaceutical use of lipases related to the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 2, optionally...
Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as...
Controlled release of growth factors and signaling molecules for promoting
The present invention comprises compositions, methods, and devices for delivering angiogenic factors and signaling molecules to a target tissue, and controlling...
Compositions and methods for preventing erythropoietin-associated
The inventors have discovered that both soluble erythropoietin-binding protein and antibodies against the erythropoietin-binding protein, when they are...
Compositions and methods for treating amyotrophic lateral sclerosis
The invention relates to pharmaceutical compositions, kits, methods, and uses for the treatment of amyotrophic lateral sclerosis. In particular, the invention...
Anti-tumor drug, medicament, composition, and use thereof
A method for the treatment of cancers and/or tumors by administration of a polypeptide having the sequence SEQ ID NO:4 or a polypeptide having an amino acid SEQ...
Pristinamycin compositions, LpxC compositions, their improvements, and
New improved formulations comprising a first composition and a second composition, the first composition being a streptogramin, the second composition being an...
Treating liver diseases
This document provides methods and materials related to treating liver conditions. For example, the methods and materials relating to the use of cAMP inhibitors...
Treatment of Ras-expressing tumors
The present invention provides compositions and methods for the treatment of /?.alpha.s-expressing tumors using at least one DAC inhibitor (e.g., romidepsin).
Safe desmopressin administration
Disclosed is a family of intranasal spray dispensers for administering uniform low doses of desmopressin so as to achieve safe antidiuresis in human patients....
Melanotropin ligands for skin care
A melanocortin 1 receptor (MC1R) peptide ligand-elastic vesicle complex. The MC1R peptide ligand is modified by coupling the MC1R ligand to a functionality or...
Modulating disease through genetic engineering of plants
In certain embodiments transgenic plants (e.g., transgenic tomatoes) are provided that comprise cells that express a peptide one or more domains of which...
Combination therapy with WT1 peptide vaccine and temozolomide
The present invention relates to combination therapy for cancer with a WT1 peptide vaccine and temozolomide.
Lissencephaly therapeutic agent
An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly...
Use of cytokine-releasing, biodegradable particles in hyaluronic acid for
the treatment of cartilage defects,...
The present invention relates to a composition comprising, or consisting of 2-50 mg/ml hyaluronic acid, 0.1-500 mg/ml of biodegradable particles with an average...
Eye-refreshing agent to eliminate and alleviate eye fatigue and discomfort
An eye-refreshing agent, the raw materials of which include mung bean germs, eucalyptus leaves, mint leaves, clove leaves, camphor leaves and borneol. The plant...
Cannabidiol (CBD) enriched alcohol
A cannabinoid enriched alcohol composition for human consumption and method of manufacture for the composition are disclosed. The composition includes by weight...
Method for prevention and treatment of Streptococcus parauberis infections
A composition includes an isolated bacteriophage Str-PAP-1 having the ability to kill Streptococcus parauberis cells specifically by infecting the same, and may...
Porcine lactic acid bacterial strains
Described herein are porcine lactic acid bacterial strain compositions and processes of obtaining porcine lactic acid bacterial strains. Further aspects of the...
Compositions and methods for treatment of microbial infections
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The...
Induction of mucosal tolerance to antigens
The present invention relates to the induction of tolerance to antigens, by mucosal, preferably oral delivery of the antigen in combination with an...
Individualized bacterial treatment of pancreatic cancer
An individualized bacterial treatment of cancer is provided. The treatment includes a strain of bacteria modified by in-vivo passage through tumor grafts in...
Immunostimulatory compositions and methods of manufacture
Immune-stimulatory compositions and methods of manufacture are described with an unexpectedly greater immunostimulatory effect on the immune system than the...
Immunomodulation using placental stem cells
The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods...
Triterpenoids and compositions containing the same
The present invention provides triterpenoids produced from natural compounds such as oleanolic acid, ursolic acid, betulinic acid, and hederagenin.
Bone grafts including osteogenic stem cells, and methods relating to the
Bone grafts and constructs including stem cells are provided. Example bone grafts include osteogenic stem cells seeded on a scaffold of osteoconductive...
Composition for treating intraventricular hemorrhage in preterm infants
comprising mesenchymal stem cells
Disclosed is a composition for the prophylaxis or therapy of intraventricular hemorrhage in preterm infants comprising mensenchymal stem cells. Functioning to...
Method of selecting phosphate binder and its uses thereof
A method of selecting or determining a candidate compound suitable for use as a phosphate binder is disclosed. The candidate compound includes ferric compounds,...
Citrate-rich calcium-magnesium supplement and uses thereof
Disclosed is an effervescent preparation of calcium and magnesium with additional citric acid in a defined ratio. Also disclosed is the use of these...
Therapeutic use of hydrogen molecules
The invention concerns a kit for preventing or treating oxidative stress in humans or animals by means of therapeutically active hydrogen molecules. The...
Lipid-containing PSA compositions, methods of isolation and methods of use
The invention provides compositions comprising lipid-conjugated forms of capsular polysaccharide A (PSA) from B. fragilis (referred to herein as PSA-LT),...
Cartilage production promoter and prophylactic or therapeutic agent for
diseases associated with cartilage damage
Disclosed is a therapy which is for preventing or treating cartilage damage and diseases associated with cartilage damage, such as arthritides and...
System for improving safety and efficacy in the preparation of an
A system is disclosed for preparing a hypodermic injection site comprising a visibility enhancer for an injection site and a post injection hypodermic puncture...
Preparation for use of aspartate and vitamin B12 or biotin for regulating
It has been found that high amounts of aspartate equivalents in combination with vitamin B12 and/or biotin, especially in relative absence of glutamate...
Defibrotide for use in prophylaxis and/or treatment of graft versus host
Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD) in humans is disclosed, preferably in hematopoietic stem cell...
Compositions and methods for treating viral infections
The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co...
Melanogenesis effect of saponins of gynostemma pentaphyllum
The present invention provides composition and method for inducing melanogenesis. The composition comprising an effective amount of saponins extracted from...
Methods, compositions, and formulations for preventing or reducing adverse
effects in a patient
The present invention provides methods, compositions, formulations, and kits related to acadesine, or a prodrug, analog, or salt thereof, and/or a blood...
Targeted delivery of anti-fungal agents
The present application discloses a targeting composition that actively targets chitin-like substances, such as those found in fungi, protists, arthropods,...
HDAC 6 inhibitor-based methods for treating cancer
This invention provides methods for treating a subject afflicted with cancer, comprising concurrently administering (i) an HDAC 6-selective inhibitor and (ii) a...
Application of depolymerized holothurian glycosaminoglycans (DHG) in
preparation of drug for prevention and...
The present invention discloses an application of depolymerized holothurian glycosaminoglycans (DHG) in preparation of a drug for the prevention and treatment...
Methods for providing sialylated oligosaccharides
The invention relates to a method for providing analogs of human milk oligosaccharides (HMO), in particular oligosaccharides containing terminal sialic acid....
Methods for decreasing the incidence of necrotizing enterocolitis in
infants, toddlers, or children using human...
Disclosed are methods of reducing the incidence of necrotizing enterocolitis in an infant, toddler, or child using nutritional compositions including human milk...
Therapeutic compositions comprising imidazole and imidazolium compounds
Therapeutic compositions comprising substituted imidazole or imidazolium compounds may be used for a number of medical purposes, such as treatment of...
Cyclophosphamide in combination with immune therapeutics
The present invention relates to methods of treating a cancer and in particular, a B-cell derived cancer, using a lymphocytotoxic but hematopoeitic cell sparing...
Topical minocycline compositions and methods of using the same
Topical minocycline compositions with reduced fluorescence are provided. In some instances, the compositions include an amount of a minocycline active agent...
Pharmaceutical formulation containing glycosaminoglycan
A pharmaceutical formulation containing a glycosaminoglycan is provided. In this pharmaceutical formulation, a glycosaminoglycan layer surrounding a drug layer...