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Patent # Description
US-9,539,264 Use of 2-methylene-19-nor-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism in...
Disclosed are methods of administering 2-methylene-19-nor-(20S)-1.alpha.,25-dihydroxyvitamin D.sub.3 to treat and/or prevent secondary hyperparathyroidism...
US-9,539,263 Subcutaneously administered anti-IL-6 receptor antibody for treatment of systemic sclerosis
The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA),...
US-9,539,262 Ophthalmic composition comprising a prostaglandin
The present invention relates to a pharmaceutical composition suitable for ophthalmic use comprising one or more prostaglandin derivatives or salts, a...
US-9,539,261 Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration
The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising...
US-9,539,260 Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates...
US-9,539,259 Compounds and methods of use thereof for treating neurodegenerative disorders
Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
US-9,539,258 Quinazoline derivatives for the treatment of cancer diseases
The present invention relates to the use of quinazolines of formula (I), ##STR00001## wherein the groups R.sup.a to R.sup.d have the meanings given in the...
US-9,539,257 Method of treating cancer
Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or...
US-9,539,256 Modulators of exchange proteins directly activated by cAMP (EPACS)
Embodiments of the invention are directed to compounds that inhibit an activity of EP AC proteins and methods of using the same. The inventors have developed a...
US-9,539,255 Solid forms of an epidermal growth factor receptor kinase inhibitor
The present invention provides a solid form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibit desirable...
US-9,539,254 Mutant ROS expression in human cancer
The invention provides the identification of the presence of mutant ROS protein in human cancer. In some embodiments, the mutant ROS are FIG-ROS fusion proteins...
US-9,539,253 Pyrimidine diol amides as sodium channel blockers
The present disclosure provides pyrimidine diol amides of Formula (I), and the pharmaceutically acceptable solvates and prodrugs thereof, wherein A.sup.1, X,...
US-9,539,252 Piperazine-substituted benzothiophene derivatives as antipsychotic agents
Provided is a superior, novel heterocyclic compound with improved solubility in oil such as sesame oil and benzyl benzoate, which has a broader treatment...
US-9,539,251 Combination therapy of a type II anti-CD20 antibody with a selective Bcl-2 inhibitor
The present invention is directed to a combination therapy involving a type II anti-CD20 antibody and a selective Bcl-2 inhibitor for the treatment of a patient...
US-9,539,250 Salt and crystalline forms thereof of a drug
A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events...
US-9,539,249 PPAR gamma agonists for treatment of multiple sclerosis
Methods of treatment of multiple sclerosis (MS) with PPAR.gamma. agonists, and in particular with the compound of formula (I) known as INT131: ##STR00001##
US-9,539,248 Agent for ameliorating chronic obstructive pulmonary disease
This invention provides a safe and effective agent for ameliorating chronic obstructive pulmonary disease (COPD) that has both a bronchodilator effect and an...
US-9,539,247 Nutraceutical composition for the treatment of excess weight and moderate hypercholesterolemia/dysglycemia
A nutraceutical composition is provided for the treatment of excess weight and moderate hypercholesterolemia/dysglycemia, comprising: Berberine, Monacolin K,...
US-9,539,246 Methods and compositions for treating nephrogenic diabetes insipidus
Disclosed is a treatment of diabetes insipidus. Methods of treating diabetes insipidus disorders associated with P2Y receptors using the compounds and...
US-9,539,245 Combination of immunotherapies with activators of Tie-2
The present invention relates to combination therapies comprising at least one activator of Tie-2 and immunotherapies that target immune checkpoints....
US-9,539,244 FXR (NR1H4) binding and activity modulating compounds
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the...
US-9,539,243 Triazole compounds that modulate HSP90 activity
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to...
US-9,539,242 Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence
Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol...
US-9,539,241 Apparatus and method for reconstituting a pharmaceutical and preparing the reconstituted pharmaceutical for...
An apparatus and method for preparing a pharmaceutical for transient application includes a tray having a sealed compartment, a vial of an ophthalmic...
US-9,539,240 Drug combinations and methods for reducing or maintaining cholesterol or HDL/LDL levels
The present specification discloses compositions comprising a pharmaceutical composition to reduce or maintain LDL and/or cholesterol levels in an individual...
US-9,539,239 Compositions and methods for treatment of neurodegenerative disease
Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
US-9,539,238 Pharmaceutical composition comprising a biguanide derivative as an active ingredient for preventing or treating...
The present invention provides novel uses of a biguanide derivative for preventing or treating glioblastoma. The compound of Formula 1 and its pharmaceutically...
US-9,539,237 Compositions and methods for drug-sensitization or inhibition of a cancer cell
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause ...
US-9,539,236 Pharmaceutical composition for preventing or treating cancer
Exemplary embodiments relate to a novel anticancer composition including a compound represented by chemical formula 1 or pharmaceutically acceptable salt...
US-9,539,235 Methods for Alzheimer's disease treatment and cognitive enhancement
The present invention relates to compositions and methods to modulate .alpha.-secretase and/or to improve cognitive ability. The invention further relates the...
US-9,539,234 Treatment of circadian rhythm disorders
Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light perception...
US-9,539,233 Gallium formulation for the treatment and prevention of infectious diseases
A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as Staphylococcus aureus, Rhodococcus...
US-9,539,232 Calebin A for osteoporosis
Disclosed is the therapeutic potential of Calebin A for osteoporosis (bone loss) caused by aging or chronic disease conditions like cancer. Calebin A is shown...
US-9,539,231 Method for treating triple-negative breast cancer using AMPI-109
A targeted approach toward the treatment of TN breast cancer by using AMPI-109 is disclosed. AMPI-109 is a compound with remarkable "cancer-specific"...
US-9,539,230 Composition for reducing new-onset diabetes
A medical composition for reducing the rate of new-onset diabetes caused by administration of a statin or for inhibiting an increase in blood glucose level by...
US-9,539,229 Intestinal tract-protecting agent containing hydroxylated fatty acid
The present invention provides an intestinal tract-protecting agent, an agent for the prophylaxis or improvement of a disease caused by damage in intestinal...
US-9,539,228 Composition containing lysine as a nutritional supplement or treatment in the case of herpes
The invention relates to a composition comprising, related to a daily dose of the composition, as its active ingredients L-lysine ranging from .gtoreq.750 mg to...
US-9,539,227 Pharmaceutical composition for the prevention or treatment of inflammatory diseases or immune diseases...
The present invention relates to the novel use (anti-inflammatory activity) of Ramalin isolated from the Antarctic lichen Ramalina terebrata, and more...
US-9,539,226 Composition containing serine as an active ingredient for the prevention and treatment of fatty liver diseases,...
The present invention is related to a composition comprising a serine as an active ingredient for treating or preventing fatty liver diseases. The inventive...
US-9,539,225 Anemia of cancer improving/prophylactic agent
A method for ameliorating and/or preventing cancerous anemia includes administering to a subject in need thereof an agent containing 5-aminolevulinic acid (ALA)...
US-9,539,224 Nutritional intervention for improving muscular function and strength
The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D...
US-9,539,223 Methods for treating bacterial infections
The invention comprises methods for treating and preventing a bacterial infection in a subject, methods for preparing a medicament for use in treating and...
US-9,539,222 Methods to inhibit intracellular growth of bacteria and to treat bacteria-mediated diseases
Disclosed is a method of preventing, treating or inhibiting bacterial infections. The method comprises administering at least one of the compounds disclosed...
US-9,539,221 Method of treating airway diseases with .beta.-adrenergic inverse agonists
The use of .beta.-adrenergic inverse agonists provides a new and highly efficient way of treating a number of pulmonary airway diseases, including asthma,...
US-9,539,220 Methods for treating suicidal ideation
Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal...
US-9,539,219 Pharmaceutical compositions of carotenoid chylomicrons
The present invention provides pharmaceutical compositions comprising a chylomicron and a carotenoid. The present invention also provides pharmaceutical...
US-9,539,218 Prevention and treatment of thromboembolic disorders
The present invention relates to the field of blood coagulation, more specifically it relates to a method of treating a thromboembolic disorder by administering...
US-9,539,217 Nanoparticle compositions
The present invention provides, among other things, nanoparticle compositions including a plurality of nanoparticles, each of which is comprised of a...
US-9,539,216 Multi-phase, multi-compartment, capsular delivery apparatus and methods for using same
A multi-compartment capsule, comprising, a first receiving chamber comprising at least one ingredient having a first physical state, wherein said ingredient is...
US-9,539,215 Method for preparing hydro/organo gelators from disaccharide sugars by biocatalysis and their use in...
A method for preparing hydro/organo gelators from disaccharide sugars by biocatalysis and their use in enzyme-triggered drug delivery. Controlled delivery of an...
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