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Patent # Description
US-9,546,383 Human pluripotent embryonic stem cells produced by nuclear transfer using a somatic cell nucleus treated with...
Human pluripotent embryonic stem cells produced by somatic cell nuclear transfer as well as methods of making and using said human pluripotent embryonic stem...
US-9,546,382 Hyperactive piggybac transposases
The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same,...
US-9,546,381 Use of anticoagulants in the production of recombinant proteins in the milk of transgenic animals
The invention relates to the production of recombinant human fibrinogen (rhFib) in the milk of transgenic mammalian animals. This production and subsequent...
US-9,546,380 MGMT-based method for obtaining high yields of recombinant protein expression
The present invention relates to a novel enhancer of protein production in host cells. It discloses a vector for expressing recombinant proteins in these cells,...
US-9,546,379 Compositions and methods for treating type 1 and type 2 diabetes and related disorders
The invention features compositions comprising in vitro generated beta cells capable of glucose-stimulated insulin secretion, methods of inducing beta cell...
US-9,546,378 Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis
A novel Bacillus thuringiensis crystal protein exhibiting insect inhibitory activity is disclosed. Growth of Lygus insects is significantly inhibited by...
US-9,546,377 Methods for the identification of genes involved in abiotic stress tolerance in plants
Methods are described for the identification of genes useful for conferring tolerance in plants to abiotic stress. Transgenic plants and seeds comprising the...
US-9,546,376 Gene for increasing the production of plant biomass and/or seeds and method for use thereof
A technique by which the production of plant biomass can be significantly increased is provided. A gene encoding protein phosphatase 2C having 3 consensus...
US-9,546,375 Influenza virus immunizing epitope
A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of a novel...
US-9,546,374 Down-regulation of gene expression using artificial microRNAs
Isolated nucleic acid fragments comprising precursor miRNAs, and artificial miRNAs and their use in down-regulating gene expression are described.
US-9,546,373 Disease resistant plants
The present invention relates to a plant, which is resistant to a pathogen of viral, bacterial, fungal or oomycete origin, wherein the plant has a reduced...
US-9,546,372 Regulatory elements and uses thereof
The present application provides novel regulatory elements including promoter sequences from marine microorganisms. The application further discloses DNA...
US-9,546,371 Chimeric polynucleotides and polypeptides enabling secretion of a polypeptide of interest in association with...
The present invention concerns a chimeric polypeptide comprising several polypeptide domains, which is capable of being secreted in association with membrane...
US-9,546,370 QSOX1 as an anti-neoplastic drug target
The present invention provides methods for tumor treatment by administering an inhibitor of quiescin sulfhydryl oxidase 1 (QSOX1), compositions comprising such...
US-9,546,369 Multicistronic expression constructs
Some aspects of this invention provide nucleic acid constructs for transgene expression. Some aspects of this invention provide multicistronic nucleic acid...
US-9,546,368 Methods for modulating metastasis-associated-in-lung-adenocarcinoma-transcript-1 (MALAT-1) expression
The present embodiments provide compounds and methods for reducing expression of Metastasis-Associated-in-Lung-Adenocarcinoma-Transcript-1 (MALAT-1) RNA and/or...
US-9,546,367 siRNA compositions and methods for inhibiting gene expression in tumor initiating cells of breast cancer
Disclosed are methods and compositions for siRNA-mediated therapy of mammalian diseases. In particular, compositions and methods are disclosed for treatment of...
US-9,546,366 Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and...
The present disclosure relates generally to cancer and particularly to breast cancer including estrogen sensitive, estrogen resistant and triple negative breast...
US-9,546,365 MicroRNA-198 as a tumor suppressor in ovarian cancer
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is...
US-9,546,364 Synthetic lariat RNA for RNA interference
Provided herein are compositions for the modification of gene expression by RNA interference using a microRNA (miRNA) guide strand precursor. Methods of making...
US-9,546,363 Method for stabilizing ascorbic acid oxidase
Provided are: a method for stabilizing an ascorbic acid oxidase; a method for preserving an ascorbic acid oxidase; and a stabilized composition of an ascorbic...
US-9,546,362 Genes and proteins for alkanoyl-CoA synthesis
Polypeptides having alkanoyl-CoA activity have been identified and characterized, as have nucleic acids encoding these polypeptides. Expression or...
US-9,546,361 Thermally stable enzymes, compositions thereof and methods of using same
Described herein are proteins having lyase activity and nucleic acid sequences which code therefor; along with methods of expressing, isolating, purifying, and...
US-9,546,360 Gain-of-function ADAMTS13 variants resistant to auto antibody inhibition and methods of use thereof
Compositions and methods for the treatment of thrombotic thrombocytopenic purpura are disclosed.
US-9,546,359 Method for engineering proteases and protein kinases
Provided are methods for protein engineering, such as engineering proteases or kinases. The methods may utilize yeast display and/or ER sequestration of...
US-9,546,358 Compositions and methods for reducing background DNA amplification
Compositions are provided that include a plurality of small molecules selected from the group consisting of an amide, urea or acetone having a molecular weight...
US-9,546,357 UGT8 mini-promoters
Isolated polynucleotides comprising a UGT8 mini-promoters are provided. The mini-promoter may be operably linked to an expressible sequence, e.g. reporter...
US-9,546,356 Recombinant yeast and substance production method using the same
Substance productivity is improved by introducing a metabolic pathway for synthesis of acetyl-CoA or acetic acid from glucose-6-phosphate into yeast. Acetic...
US-9,546,355 Conditional replicating cytomegalovirus as a vaccine for CMV
The present invention relates to methods of inducing an immune response to cytomegalovirus (CMV) using a genetically modified CMV that is conditionally...
US-9,546,354 Z cells activated by zinc finger-like protein and uses thereof in cancer treatment
Immune cells (Z cells) activated by zinc finger-like protein that regulates apoptosis (Zfra) and uses thereof in cancer treatment.
US-9,546,353 Optimized and defined method for isolation and preservation of precursor cells from human umbilical cord
The present invention refers to an optimized and defined method for isolation and preservation of precursor cells from human umbilical cord. Besides being...
US-9,546,352 Coated dehydrated microorganisms with enhanced stability and viability
The present invention relates to coated dehydrated microorganisms comprising a dehydrated microorganism surrounded by at least one coating, said coating...
US-9,546,351 Method and system for processing biomass
A method and system for processing biomass. The method uses an apparatus with a housing, a rotor inside of the housing, and a plurality of protrusions extending...
US-9,546,350 Methods and devices related to a regulated flow electroporation chamber
The electroporation chamber and its related devices combine the features of an electroporation chamber that acts as a manifold for regulation of sample flow...
US-9,546,349 Supports for cell culture and cell sheet detachment and methods for cell sheet detachment
The invention creates a support for cell culture and cell sheet detachment which has a substrate, whose surface is coated with a conjugate having a disulfide...
US-9,546,348 Conical brewing device with nesting supporting member
Brewing assemblies and kits are generally disclosed herein. In particular, a brewing assembly comprising an upper member having a generally conical lower...
US-9,546,347 Combination product having two separate cleaning compositions, both having a high viscosity
The invention relates to fluid washing or cleaning products which are present as combination products comprising a packaging means and at least two fluid...
US-9,546,346 Use of polyethylene glycol to control the spray pattern of sprayable liquid abrasive cleansers
Liquid abrasive cleanser compositions sprayable through conventional manual trigger sprayers comprise a polyalkylene glycol, a nonionic surfactant, a pH...
US-9,546,345 Synergistic stain removal through novel chelator combination
The invention relates to a concentrated detergent composition comprising an alkali metal carbonate, methylglycinediacetic acid, glutamic acid N,N-diacetic acid,...
US-9,546,344 Color-protecting detergent
The color protection properties of detergents when used to wash colored textiles is to be improved. This is substantially achieved in that polymers are used...
US-9,546,343 Low-water, liquid detergent having increased fat-dissolving power
The invention relates to a liquid detergent or cleaning agent, comprising a) an anionic surfactant neutralized with an amine, b) an alkoxylated oxo alcohol...
US-9,546,342 Complete saponification and acidulation of natural oil processing byproducts
The present invention generally provides a process for treating a soapstock. The present invention more particularly provides systems and methods for treating a...
US-9,546,341 Low ash lubricant and fuel additive comprising polyamine
A metal-free detergent and antioxidant additive comprising the reaction product of an acidic organic compound, a boron compound, a polyamine such as...
US-9,546,340 Ultra low phosphorus lubricant compositions
A low-phosphorus lubricating composition has less than 600 ppm phosphorus, comprising at least 85 weight % of a lubricating base blend, and an additive...
US-9,546,339 Method for reducing crystallization of 1-[di(4-octylphenyl)aminomethyl]tolutriazole
1-[di(4-octylphenyl)aminomethyl]tolutriazole is prepared in a mineral oil and blended with a liquid alkylated diphenylamine. The liquid product shows increased...
US-9,546,338 Redox couple-based mitigation of fluid-flow-driven electrochemical surface degradation
The present disclosure relates to methods, systems, hydraulic fluids and additives for reducing the rate of surface current degradation for components in a...
US-9,546,337 Lubricant composition
The present invention provides a lubricating oil composition comprising a lubricating base oil, and at least one ester additive selected from a first ester that...
US-9,546,336 Compositions comprising estolide compounds and methods of making and using the same
Provided herein are compositions comprising at least one estolide compound of formula: ##STR00001## in which n is an integer equal to or greater than 0; m is...
US-9,546,335 Engine lubricant composition
Lubricant compositions include: (a) one or more polyalkylene glycol base oils obtained by polymerization or copolymerization of alkylene oxides comprising from...
US-9,546,334 Refrigerating machine oil, and working fluid composition for refrigerating machine which is produced using same
Provided is a refrigerating machine oil which comprises an ester between a polyol consisting of at least one of pentaerythritol and dipentaerythritol...
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