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Patent # Description
US-9,550,765 Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors
The present disclosure describes thiazole and pyridine carboxamide derivatives, their compositions and methods of use. The compounds inhibit the activity of the...
US-9,550,764 Fused heterocyclic compounds and their use
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts, hydrates and solvates thereof for use in the treatment of cancer:...
US-9,550,763 Heterocyclic ring and carbocyclic derivative
The present invention provides novel compounds having a P2X.sub.3 and/or P2X.sub.2/3 receptor antagonistic effect, e.g. a compound of Formula (I): ##STR00001##...
US-9,550,762 Cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use
The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula...
US-9,550,761 Modulators of ATP-binding cassette transporters
The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane...
US-9,550,760 Substituted indol-5-ol derivatives and their therapeutic applications
The present invention relates generally to the use of compounds to treat a variety of disorders, diseases and pathologic conditions and more specifically to the...
US-9,550,759 Nitrocatechol derivatives as COMT inhibitors
New compounds of formula I are described. The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral...
US-9,550,758 Heterocyclic derivatives and their use in the treatment of neurological disorders
The invention relates to novel heterocyclic compounds of the formula ##STR00001## in which all of the variables are as defined in the specification,...
US-9,550,757 Nuclear transport modulators and uses thereof
The invention generally relates to the field of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to new substituted-heterocyclic azole...
US-9,550,756 Pyridazinone compounds as phosphodiesterase inhibitors and methods of treating disorders
The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia...
US-9,550,755 Complement pathway modulators and uses thereof
The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present...
US-9,550,754 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy
The present invention relates to 4,5-dihydropyrazole derivatives of the formula (I) ##STR00001## and physiologically tolerated salts thereof which are GlyT1...
US-9,550,753 Mono quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for...
US-9,550,752 Triazolinthione derivatives
The present invention relates to novel triazolinthione derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and...
US-9,550,751 Processes for the preparation of pesticidal compounds
The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
US-9,550,750 Indoline compounds as aldosterone synthase inhibitors
This invention relates to indo line compounds of the structural formula I, or their pharmaceutically acceptable salts, wherein the variables are defined herein....
US-9,550,749 Endoparasite control agent and method for using the same
An object of the present invention is to provide a novel endoparasite control agent as a parasiticide, an antiprotozoal or the like. Provided is an endoparasite...
US-9,550,748 Cyclic carbonate monomers and polymers prepared therefrom
A cyclic carbonate monomer including the reaction product of (a) a divinylarene dioxide, and (b) carbon dioxide; a process for making the cyclic carbonate...
US-9,550,747 Dapagliflozin crystalline form and preparation method thereof
The present invention relates to a new crystalline form of dapagliflozin represented by formula (I). The crystalline form has a characteristic absorption peak...
US-9,550,746 Benzofuran-2-sulfonamides derivatives as chemokine receptor modulators
The present invention relates to novel benzofuran-2-sulfonamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their...
US-9,550,745 Method for preparing 4-aminobut-2-enolides
Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are reduced to the corresponding 2,2-difluoroethylamine...
US-9,550,744 Vitamin C prodrugs and uses thereof
Described herein are vitamin C prodrugs of Formula (I), (II), or (III), and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical...
US-9,550,743 Process for the preparation of an antidepressant and the intermediates thereof
The present invention relates to a process for the preparation of 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine of formula (I), also known as...
US-9,550,742 11-OXO-10,11-dihydrodibenzo[B,F][1,4]thiazepine S-oxide derivatives and their use as dopamine D2 receptor...
The disclosure includes compounds and pharmaceutically acceptable salts of Formula (I). Certain compounds and salts of Formula (I) are selective inhibitors of...
US-9,550,741 Benzoisothiazole compounds and methods of treating schizophrenia
Disclosed are benzoisothiazole compounds and a use in the preparation of anti-schizophrenia drugs. The benzoisothiazole compounds of the present invention not...
US-9,550,740 Antimicrobial compounds
Provided are compounds which are useful for controlling microorganisms in aqueous or water-containing systems or in systems which are exposed to moisture,...
US-9,550,739 Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce...
US-9,550,738 Bicyclic compounds as kinases inhibitors
The present invention is directed to novel bicyclic compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The...
US-9,550,737 TNF -.alpha. modulating benzimidazoles
A series of benzimidazole derivatives, being potent modulators of human TNF.alpha. activity, are accordingly of benefit in the treatment and/or prevention of...
US-9,550,736 Salt of bicyclic aromatic anions for Li-ion batteries
A method for obtaining salts of bicyclic imidazole compounds (V) having general structural formulae in which A represents a monovalent cation, X represents...
US-9,550,735 Process for the preparation of ivacaftor and solvates thereof
The present invention provides process for the preparation of ivacaftor and solvates thereof.
US-9,550,734 Bivalent linkers and conjugates thereof
Bivalent linkers to be included in or for preparing vitamin, drug, diagnostic agent, and/or imaging agent conjugates are described.
US-9,550,733 Fluorinated derivatives of 3-hydroxypyridin-4-ones
Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a...
US-9,550,732 Salt of pyrrolidin-3-yl acetic acid derivative and crystals thereof
An organic carboxylic acid salt of 2-[(3S,4R)-1-{[2-chloro-6-(trifluoromethyl)phenyl]methyl}-3-{[1-(cyclohex- -1-en-1-ylmethyl)...
US-9,550,731 Method for phase transfer synthesis of organic peroxides
Processes and systems for synthesizing organic peroxides are provided. One or more of the reactions described herein may be performed in a continuous reactor,...
US-9,550,730 Merocyanine derivatives
Disclosed are compounds of formula (1) and (2) and/or E/E-, E/Z- or Z/Z geometrical isomer forms thereof; wherein R1-R5, R1-R11 and A are defined as in...
US-9,550,729 Mixed metal oxide catalysts
Catalytic compositions are provided that are effective for providing increased acrylonitrile product without a significant decrease in hydrogen cyanide and/or...
US-9,550,728 Thermo-responsive draw solute for forward osmosis and method for water desalination and purification using the same
The present invention relates to a thermo-responsive draw solute that can be applied to water desalination and purification based on forward osmosis. The...
US-9,550,727 Method for the crystallization of 2-(4-N,N-diethyl amino-2-hydroxy-benzoyl)-benzoic acid-n-hexyl ester
The present invention relates to a method for the crystallization of n-hexyl 2-(4-N,N-diethylamino-2-hydroxybenzoyl)benzoate, to a method for the production of...
US-9,550,726 Methods for decolorizing compositions comprising betaines
The invention relates to a process for decolorizing a composition comprising a betaine comprising the steps of (a) providing a solution of the composition in...
US-9,550,725 Lipophilic polyalkylenepolyamines by homogeneously catalyzed alcohol amination
Process for the preparation of lipophilic polyalkylenepolyamines by homogeneously catalyzed alcohol amination, where aliphatic amino alcohols are reacted with...
US-9,550,724 Diphenylamine compounds and production method thereof
An inexpensive and convenient production method of diphenylamine compounds is provided, that can solve problems in the conventional technology such as decrease...
US-9,550,723 Radically curable compound, method for producing radically curable compound, radically curable composition,...
Provided is a positive photoresist composition excellent in terms of heat resistance. A radically curable compound is represented by a general formula (1) below...
US-9,550,722 Compositions and methods of use of phorbal esters for the treatment of stroke
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment and prevention of stroke and the sequelae...
US-9,550,721 Method for preparing dimethyl 1,4-cyclohexanedicarboxylate and method for preparing 1,4-cyclohexanedimethanol
A method for preparing dimethyl 1,4-cyclohexanedicarboxylate (DMCD) is provided. The method includes hydrogenating dimethyl terephthalate (DMT) under a...
US-9,550,720 Method for producing an .omega.-halo-2-alkynal
Provided is a method for industrially producing a conjugated Z-alken-yn-yl acetate such as Z-13-hexadecen-11-yn-yl acetate which is a sex pheromone component of...
US-9,550,719 Process for the preparation of 3-aryl-2-hydroxy propanoic acid compounds
The present disclosure provides a process for synthesis of 3-aryl-2-hydroxy propanoic acid derivatives of formula (S)-1. wherein R.sub.1 represents H or...
US-9,550,718 Lipid comprising polyunsaturated fatty acids
The present invention relates to extracted plant lipid, comprising fatty acids in an esterified form.
US-9,550,717 Method for recovering anionic fluorinated emulsifier
A method for recovering an anionic fluorinated emulsifier comprises contacting a strongly basic ion exchange resin having an anionic fluorinated emulsifier...
US-9,550,716 Process for treprostinil salt preparation
Disclosed is a process for preparing a treprostinil salt. The process involves the step of dissolving treprostinil in a water-miscible organic solvent to form a...
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