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Patent # Description
US-9,550,012 Tissue scaffolds having bone growth factors
The invention provides a novel composite bone graft system utilizing a porous collagen scaffold having a matrix impregnated with calcium phosphate particles and...
US-9,550,011 Surface coatings for biological implants and prostheses
A functionalized polymer system is described herein for preparing and/or modifying biological implants and prostheses. In one aspect, the polymer system once...
US-9,550,010 Methods of treating degenerative bone conditions
Methods and articles of manufacture for treating patients with degenerative bone are provided. The methods are useful to improve bone quality in a localized...
US-9,550,009 Air treatment systems and methods
A system is provided for treating a space at least partially enclosed by a wall with an aerosolized compound. The system includes a discharge unit, a liquid...
US-9,550,008 Two-part, syringe-based electrochemical dispenser
A Two-part, Syringe-based Electrochemical Dispenser. The dispenser consists of a disposable syringe-like fluid storage reservoir and a reusable fluid driver....
US-9,550,007 Methods and solutions for rapidly killing or deactivating spores
Exemplary methods and systems for killing or deactivating spores include applying a fluid to a surface containing a spore; and applying direct or indirect...
US-9,550,006 Systems and methods for treatment of cabin surfaces and air
Embodiments relate generally to systems and methods for treating passenger transportation vehicle cabin surfaces and surrounding air. The methods may use...
US-9,550,005 Systems and methods for sterilization using UV light
Embodiments of this disclosure include systems, methods, and kits for sterilizing in vivo catheters using an optical fiber to deliver UV light. In an...
US-9,550,004 Ultraviolet diffusive illumination
A solution for generating ultraviolet diffusive radiation is provided. A diffusive ultraviolet radiation illuminator includes at least one ultraviolet radiation...
US-9,550,003 Installation for processing articles by electron bombardment
An installation for treating articles by radiation, the installation comprising a structure (1) having an article transport device (10) mounted thereon with a...
US-9,550,002 Phospholipid analogs as diapeutic agents and methods thereof
The present invention provides methods and uses of phospholipid ether analogs as diagnostic and therapeutic agents for numerous cancers.
US-9,550,001 Compositions, methods of synthesis and use of carbohydrate targeted agents
The invention provides D02S derivatives conjugated to monosaccharide ligands directly or through a linker and optionally chelated to a metal, wherein the D02S...
US-9,550,000 Compositions, methods, and systems for the synthesis and use of imaging agents
The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent...
US-9,549,999 Radiopharmaceutical composition
The present invention provides a .sup.99mTc-tetrofosmin radiopharmaceutical composition comprising tetrofosmin and a radioprotectant at a particular range of...
US-9,549,998 Stabilized gold nanoparticle and contrast agent
A kit for providing a contrast enhancer in a mammal for contrasting during imaging of the mammal comprises functionalized gold nanoparticles configured to be...
US-9,549,997 Optical imaging probes
The present invention relates to methods of visualizing cells especially although not exclusively in vivo using a dye, such as a dendrimer-dye molecule or...
US-9,549,996 Matrix incorporated fluorescent porous and non-porous silica particles for medical imaging
A silica particle for medical imaging includes a bridged silane fluorescent dye incorporated throughout the particle matrix. Copolymerization of a bridged...
US-9,549,995 Efficient synthesis of ethylenedicysteine-sugar conjugates for imaging and therapy
Novel methods of synthesis of ethylenedicysteine-sugar conjugates and therapeutic and diagnostic applications of such conjugates are disclosed. Methods of...
US-9,549,994 Compositions of nicardipine and sulfoalkylated .beta.-cyclodextrin
Compositions of an inclusion complex of nicardipine or a pharmaceutically acceptable salt thereof and a sulfoalkylated .beta.-cyclodextrin. The compositions...
US-9,549,993 Specific delivery of toxins conjugated with antibodies to activate matripase
Disclosed are antibody drug conjugates (ADC) that include highly potent toxic agents with specific antibodies to target tumors. Also disclosed are related...
US-9,549,992 Folate receptor binding conjugates of antifolates
Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating...
US-9,549,991 Chemical and biochemical adducts as biomarkers for organophosphate exposure
The present disclosure provides organophosphorous (OP) compounds of Formula (I), Formula (II) and Formula (III): OP-Peptide-Linker-CP (I), OP-Peptide-Linker ...
US-9,549,990 Derivatisation of erythropoietin (EPO)
The present invention relates to a compound which is a polysaccharide derivative of EPO, or of an EPO like protein, wherein the polysaccharide is anionic and...
US-9,549,989 Modified release formulations containing drug-ion exchange resin complexes
A particulate, barrier coated drug-anion exchange resin complex comprising a core composed of an acidic drug complexed with a pharmaceutically acceptable...
US-9,549,988 Pharmaceutical compounds targeted by MIF affinity-tethered moieties
There is disclosed a compound, a pharmaceutical composition and a method of treatment using a pharmaceutical composition comprising a tethering moiety that is...
US-9,549,987 Glucose responsive hydrogel comprising PBA-grafted hyaluronic acid (HA)
Polymer composition comprising a mixture of PBA modified HA polymer grafted on at least a hydroxyl with a group comprising phenylboronic acid and Cis-diol...
US-9,549,986 Block copolymer, liquid composite thereof, nucleic acid preparation, preparation methods therefor, and use thereof
Provided are a polycaprolactone-polyphosphate block copolymer, a liquid composite formed by the block copolymer, a nucleic acid preparation, preparation methods...
US-9,549,985 Compositions comprising polymers prepared from 2-hydroxyalkyl acids
Described herein are compositions comprising polymers prepared by melt polycondensation of 2-hydroxyalkyl acids. Methods of making and using the compositions...
US-9,549,984 Probiotic oral dosage forms and method of enhancing the stability, thereof
Provided are probiotic compositions that have enhanced stability under various storage conditions. The stability of the probiotic compositions is enhanced...
US-9,549,983 Amine cationic lipids and uses thereof
The present invention relates to lipid compounds and uses thereof. In particular, the compounds include a class of cationic lipids having an amine moiety, such...
US-9,549,982 Ultra low dose nutraceutical compositions for enhancing sleep quality and treating sleep disorders
The present technology relates to a dietary supplement, composition, nutraceutical, and/or system for inducing or treating biological responses or conditions...
US-9,549,981 Sequential antibody therapy
The invention provides a blocking ligand specific for CTLA-4 and a vascular targeting ligand/IL-2 complex, for sequential use in inhibiting the growth of tumor...
US-9,549,980 Methods of treating necrotizing enterocolitis by administering nuclear oligomerization domain-2 agonists,TLR9...
The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving...
US-9,549,979 Arabinogalactan for enhancing the adaptive immune response
The present invention discloses a composition containing Arabinogalactan for enhancing the adaptive immune response in subjects to foreign antigen(s) by...
US-9,549,978 Amino acid sequences for controlling pathogens
The present invention relates to antimicrobial peptides, isolated and purified from extracts of tilapia (Oreochromis niloticus) gills. Such peptides may be...
US-9,549,977 Use of the PACAP as a molecular adjuvant for vaccines
The present invention relates to the use of the pituitary adenylate cyclase activating peptide (PACAP) as a molecular adjuvant for vaccines. Among other...
US-9,549,976 Affinity selection of Nipah and Hendra virus-related vaccine candidates from a complex random peptide library...
The invention relates to virus-like particles of bacteriophage MS2 (MS2 VLPs) displaying peptide epitopes or peptide mimics of epitopes of Nipah Virus envelope...
US-9,549,975 Genetically engineered swine influenza virus and uses thereof
The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN)...
US-9,549,974 Method for selecting and producing vaccine components and vaccines based thereon
The invention relates to the field of vaccines against microbial infections and especially bacterial vaccines, in particular to pneumococcal vaccines. More in...
US-9,549,973 Compositions and methods comprising KLK3 or FOLH1 antigen
The present invention provides KLK3 peptides, FOLH1 peptides, recombinant polypeptides comprising same, recombinant nucleotide molecules encoding same,...
US-9,549,972 MHC-I restricted epitopes containing non-natural amino acid residues
The invention provides for the synthesis of more effective generators of a T-cell immune response by providing peptide derivatives that are MHC class...
US-9,549,971 Methods for inhibiting angiogenesis using EGFL8 antagonists
The present invention provides methods of using EGFL8 antagonists to inhibit vascular development and to treat related disorders.
US-9,549,970 Methods for producing yeast-based vaccines
The invention provides methods for culturing yeast at a neutral pH level. Yeast cultured under neutral pH conditions exhibit desirable characteristics useful...
US-9,549,969 Pharmaceutical compositions and methods
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and...
US-9,549,968 Muteins of human lipocalin 2 (LcnC,hNGAL) with affinity for a given target
The present invention relates to a novel library for the generation of muteins and to novel muteins derived from human lipocalin 2 (Lcn2, hNGAL) and related...
US-9,549,967 Regulation of sodium channels by PLUNC proteins
The present invention relates to the ability of PLUNC proteins, such as SPLUNC1 and SPLUNC2, to bind to sodium channels and inhibit activation of the sodium...
US-9,549,966 Inflammatory eye disorders
Provided herein are methods of evaluating efficacy of a treatment in a subject having eye inflammation (e.g., a subject having dry eye syndrome) and selecting a...
US-9,549,965 Pharmaceutical composition for treating a microbial infection
The present invention relates to a combination comprising at least one compound selected from the group consisting of an .alpha.-adrenergic antagonist, an...
US-9,549,964 Diagnosis, prognosis, and treatment of kidney disease
The present invention relates to the discovery that an increased fraction of albumin is carbamylated in patients suffering from kidney disease (e.g., end-stage...
US-9,549,963 Methods and compositions for preventing or treating ophthalmic conditions
The disclosure generally describes methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject, such as diabetic retinopathy,...
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