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Patent # Description
US-9,555,051 Vesicular formulations
The present invention relates to vesicular formulations for the treatment of rosacea. It also relates to a method of treating rosacea comprising administering a...
US-9,555,050 ATX modulating agents
Compounds of formula (I) can modulate the activity of autotaxin (ATX).
US-9,555,049 Arene ruthenium (II) derivatives containing iminophosphorane ligands and their use in cancer therapy
A method for providing a therapeutic benefit for a subject having a cancer is provided. A compound with an arene ruthenium (II) compound with an...
US-9,555,048 Corticosteroids for the treatment of joint pain
Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or...
US-9,555,047 Corticosteroids for the treatment of joint pain
Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or...
US-9,555,046 Crystalline anhydrate forms of a pharmaceutical
The invention provides and describes solid state 17.alpha.-ethynyl-androst-5-ene-3.beta.,7.beta.,17.beta.-triol including amorphous and crystalline forms and...
US-9,555,045 Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions
A composition for use in treating corneal and conjunctival lesions, includes a prostaglandin F2alpha or analogue, in a therapeutic amount, the composition being...
US-9,555,044 Orexin receptor antagonists
The disclosures herein relate to novel compounds of formula wherein W, X and Y.sub.1, Y.sub.2, Y.sub.3 and Y.sub.4 are defined herein, and their use in...
US-9,555,043 High purity diaminophenothiazinium compounds including methylthioninium chloride (MTC)
This invention pertains generally to the field of chemical synthesis and purification, and more specifically to methods of synthesizing and purifying certain...
US-9,555,042 Treatment for pancreatic cancer
The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a...
US-9,555,041 Neprilysin inhibitors
In one aspect, the invention relates to compounds having the formula: ##STR00001## where R.sup.1-R.sup.6, a, b, and X are as defined in the specification, or a...
US-9,555,040 Methods of treating proliferative diseases
Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[- 2,1-b][1,3]benzothiazol-2-yl]phenyl}urea,...
US-9,555,039 Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT)
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound...
US-9,555,038 Heterocycle-substituted tetracyclic compounds and methods of use thereof for the treatment of viral diseases
The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein...
US-9,555,037 Method of using vasoconstrictive agents during energy-based tissue therapy
A mammal undergoing an energy-based therapy is treated by administering at least one vasoconstrictive agent to the mammal prior to or during the procedure. The...
US-9,555,036 Pyrazolopyrimidine compounds
Compounds of formula (I) and salts thereof: ##STR00001## wherein R.sub.1 is n-C.sub.1-6alkyl or C.sub.1-2alkoxyC.sub.1-2alkyl-, R.sub.2 is halo, OH or...
US-9,555,035 Heterocyclyl compounds as MEK inhibitors
The present disclosure is related to heteroaryl compounds as MEK inhibitors. These compounds include heteroaryl compounds of formula I, their pharmaceutically...
US-9,555,034 Compositions and methods for treating skin cancer associated diseases
The invention provides compositions and methods for treating skin cancer associated diseases. Specifically, the invention relates to topically administering a...
US-9,555,033 Identification of LKB1 mutation as a predictive biomarker for sensitivity to TOR kinase inhibitors
Provided herein are methods for treating and/or preventing a cancer or a tumor syndrome in a patient, comprising administering an effective amount of a TOR...
US-9,555,032 Methods for treatment and prevention of tauopathies and amyloid beta amyloidosis by modulating CRF receptor...
Methods for treating or preventing tauopathies and/or A.beta. amyloidosis by modulating CRF receptor signaling. Accumulation of hyperphosphorlyated tau protein...
US-9,555,031 Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity
Uses of pyrrolopyrimidines with anti-Mer tyrosine kinase activity as anti-infective agents, immunostimulatory and immunomodulatory agents, anti-cancer agents...
US-9,555,030 Therapeutic uses of selected pyrazolopyrimidine compounds with anti-Mer tyrosine kinase activity
Pyrazolopyrimidine compounds, methods of use, and processes for making compounds with anti-Mer tyrosine kinase activity comprising Formula I, II, III, IV, or a...
US-9,555,029 Methods of colchicine administration
The invention provides improved methods for coadministration of colchicine with drugs metabolized by CYP3A4 (anciently referred to as cytochrome P450 isozyme...
US-9,555,028 Drug for preventing/treating ocular disease
The present invention relates to a medicament for preventing or treating an ocular disease comprising cyclo-trans-4-L-hydroxyprolyl-L-serine as an active...
US-9,555,027 Pharmaceutical composition
A preparation for oral administration comprising: a pregelatinized starch comprising N-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]-(2R,3R)-2,3-tetramethyle- ...
US-9,555,026 Solid dispersion comprising amorphous cilostazol
The present invention relates to a solid dispersion comprising cilostazol, and methacrylic acid copolymer S and/or methacrylic acid copolymer L, which is...
US-9,555,025 Ointment with excellent formulation stability
Provided is an ointment which has excellent drug stability and excellent drug uniformity. The ointment, which comprises 1 to 5% by weight of ...
US-9,555,024 Substituted (E)-N'-(1-phenylethylidene)benzohydrazide analogs as histone demethylase inhibitors
In one aspect, the invention relates to substituted (E)-N'-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are...
US-9,555,023 Pharmaceutical salts and polymorphs of a factor Xa inhibitor
The present invention provides for salts comprising a compound of Formula I and an acid that has activity against mammalian factor Xa. The present invention is...
US-9,555,022 Substituted triazolopyridines
The present invention relates to substituted triazolopyridine compounds of general formula (I): in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 are as...
US-9,555,021 Pharmaceutical compositions comprising (3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl)methanol
Disclosed herein is a pharmaceutical composition comprising (3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl)methanol and methods of using the composition to treat...
US-9,555,020 Treatments for diabetes mellitus and obesity
Methods of treatment in subjects suffering from diabetes mellitus or obesity are provided. The methods comprise the step of administering an active agent...
US-9,555,019 Granulate containing cannabinoid, method for its manufacture and oral dosage unit comprising such granulate
The present invention relates to a granulate comprising granules made up of 40-99 wt. % of lactose particles and 1-60 wt. % of a binding component that holds...
US-9,555,018 Synergistic combinations of organic acid useful for controlling microoganisms in industrial processes
The present invention provides a method of controlling bacterial contamination using synergistic interactions of antimicrobials. The invention utilizes a...
US-9,555,017 Methods of making a mixture of salts of gamma-hydroxybutyrate
Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of...
US-9,555,016 Lytic agents for use in treating intravascular clots
Agents and methods are provided for breaking down and/or assisting in the removal of clots, in embodiments chronic clots, from the vasculature. In embodiments,...
US-9,555,015 Antimicrobial compositions and methods for their use
Topical and wash compositions comprising a polymeric biguanide or a bis(biguanide) compound, a chelating agent and a buffering agent and methods for using these...
US-9,555,014 Therapeutic regimens
This invention relates to clinically useful therapeutic regimens comprising the administration of ...
US-9,555,013 Modulation of fibroblast activity
The invention includes a method for combating scarring in a subject, the method comprising administering to the subject an agent which positively modulates...
US-9,555,012 Methods for maintaining or improving health, well-being and/or a physiological function in a subject
The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition...
US-9,555,011 Formulation of active agent loaded activated PLGA nanoparticles for targeted cancer nano-therapeutics
The present invention includes compositions and methods of making an activated polymeric nanoparticle for targeted drug delivery that includes a biocompatible...
US-9,555,010 Support body for transdermal patch or transdermal preparation, and transdermal patch and transdermal...
The present invention provides a patch or patch preparation in which the anchoring property of a pressure-sensitive adhesive layer to a support is improved with...
US-9,555,009 Ciprofloxacin loaded diethylaminoethyl cellulose nanoparticles
This invention reports ciprofloxacin (CIP)-encapsulated polymeric nanoparticles and its antibacterial potential with a variety of gram positive and gram...
US-9,555,008 Synthesis of hyperbranched amphiphilic polyester and theranostic nanoparticles thereof
A method of making a hyperbranched amphiphilic polyester compound includes drying under vacuum a mixture of 2-(4-hydroxybutyl)-malonic acid and p-toluene...
US-9,555,007 Multi-layer hydrogel capsules for encapsulation of cells and cell aggregates
Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have...
US-9,555,006 PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the...
The invention relates to a pH-dependent controlled release pharmaceutical composition, comprising at least one pharmaceutical active ingredient, with the...
US-9,555,005 Extended-release topiramate capsules
An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a...
US-9,555,004 Sustained-release formulations of topiramate
Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an...
US-9,555,003 Oral solid formulation of compound anti-tubercular drug and preparation method thereof
Provided is an oral solid preparation of a compound anti-tubercular drug, wherein the active ingredients are rifampicin, isoniazid, pyrazinamide and ethambutol...
US-9,555,002 Solid pharmaceutical preparations containing copolymers based on polyethers combined with poorly water-soluble...
The invention relates to dosage forms which contain preparations of poorly water-soluble substances in a polymer matrix of polyether copolymers, said polyether...
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