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Patent # Description
US-9,567,319 Compound having higher inhibitory activity on protein kinase G and preparation method thereof
Disclosed are a compound of Formula I, ##STR00001## having higher inhibition of protein kinase G (PKG) activity and pharmaceutically acceptable salts thereof....
US-9,567,318 Substituted pyrimidine compounds and uses thereof
The present subject matter relates to a compound represented by the general formula (I) or (I') or a pharmacologically acceptable salt thereof; pharmaceutical...
US-9,567,317 Multicomponent crystalline system comprising nilotinib and selected co-crystal formers
The present invention relates to crystalline materials comprising nilotinib and a carboxylic acid, carboxylic acid ester, carboxylic acid amide or sulfonic acid...
US-9,567,316 Aminoquinoline derivatives and uses thereof
Described herein are aminoquinoline and aminoacridine based hybrids, pharmaceutical compositions and medicaments that include such aminoquinoline and...
US-9,567,315 Method for synthesis of 4-OH substituted anabaseine derivative
A method for synthesis of 4-OH substituted anabaseine derivative which is used as an .alpha..sub.7 receptor agonist is revealed. A nucleophilic substitution...
US-9,567,314 Dithiol compounds, derivatives, and uses therefor
Dithiol compounds and derivatives thereof are disclosed. The agents are useful for treating ocular disease, especially presbyopia and cataract.
US-9,567,313 Isocyanate-functional cyclic carbonates
The invention relates to a process for preparing compounds containing isocyanate groups and cyclic carbonate structures, by reacting at least A) a monomeric...
US-9,567,312 Cabazitaxel, related compounds and methods of synthesis
The invention provides new cabazitaxel isoserine ester intermediates and new synthetic methods, and a preparation method for the anti-tumour drugs cabazitaxel,...
US-9,567,311 Water dispersible, self-crosslinkable prepolymer composition
The present invention provides an economical route to environmentally friendly polymeric coatings with a high content of raw materials from renewable resources....
US-9,567,310 Benzene sulfonamide thiazole compounds
The present invention relates to compound of general formula (1) wherein R.sub.1 represents C.sub.6-C.sub.10 aryl comprising one or two fused rings, wherein...
US-9,567,309 Desferrithiocin polyether analogues
Compounds represented by structural formulas described herein, such as Structural Formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof are...
US-9,567,308 Process for the synthesis of chlorzoxazone
Disclosed is a process for the synthesis of chlorzoxazone (1) from 4-chloro-2-aminophenol and ethyl chloroformate in the presence of a base. ##STR00001## The...
US-9,567,307 Amination of aryl alcohol derivatives
Embodiments of the invention provide methods and materials for chemical cross-coupling reactions that utilize aryl alcohol derivatives as cross-coupling...
US-9,567,306 Inhibition of macrophage migration inhibitory factor in melanoma and colon cancer
Compounds and compositions are provided which inhibit MIF. Methods of treatment of melanoma and colon cancers are also provided.
US-9,567,305 Quinoxaline compounds and derivatives
The present invention provides oxazine compounds, method of using and method of making oxazine compounds and its pharmaceutical use.
US-9,567,304 Quinazolinedione derivative
The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof. ##STR00001##
US-9,567,303 Crystal of 5-hydroxy-1H-imidazole-4-carboxamide hydrate and pharmaceutical composition thereof
Provided is a method for producing 5-hydroxy-1H-imidazole-4-carboxamide.3/4 hydrate, including: reacting 2-aminomalonamide with a compound represented by the...
US-9,567,302 Carbamate compounds and of making and using same
Provided herein are carbamate compounds which may be useful in the treatment of for example, pain, solid tumors and/or obesity.
US-9,567,301 Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors
The present invention provides compounds of Formula (I-A), (I-B), and (I-C), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof....
US-9,567,300 Hexahydropentaleno derivatives, preparation method and use in medicine thereof
The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives...
US-9,567,299 Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
Inhibitors of HBV replication of formula (I) ##STR00001## including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, R.sup.1...
US-9,567,298 Crystal forms of azetidinone compounds and preparing methods thereof
The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]- ...
US-9,567,297 Method for synthesizing of thioesters by using compound as catalyst
A method for synthesizing of thioesters by using a compound as a catalyst is disclosed. The compound is represented by formula I below: ##STR00001## In formula...
US-9,567,296 Ionizable cationic lipid for RNA delivery
What are described are compounds of formula II. The compound of formula II ##STR00001## consists of a compound in which R.sub.1 and R.sub.2 are both a linear...
US-9,567,295 Drug with activity against the herpes virus family
The invention relates to medicine, and specifically to synthetic biologically active derivatives of carbopentoxysulfanilic acid. The novel substance comprises a...
US-9,567,294 Bioactive polymers
Polycondensation products of aminoguanidine and/or 1,3-diaminoguanidine with one or more diamines are provided including polyguanidine derivatives of the...
US-9,567,293 Combined synthesis of a nitrile-ester/acid and of a diester/diacid
A method for the combined synthesis of a mono-unsaturated nitrile-ester(acid) and of a bi-functional carbonyl compound, wherein it includes a step including the...
US-9,567,292 Process for preparation of 2,3-dihydroxy benzonitrile
The present invention relates to one pot process for the preparation of 2,3-dihydroxy benzonitrile from 2,3-dialkoxy benzoic acid without prior isolation of the...
US-9,567,291 N-(4-(bis(4-(dimethylamino)phenyl)methylene)-8-(dimethylamino)
This disclosure relates to N-(4-(bis(4-(dimethylamino)phenyl)methylene)-8 -(dimethylamino)naphthalen-1(4H)-ylidene)-N-methylmethanaminium, derivatives, and uses...
US-9,567,290 Esters of N-acyl derivatives of amino acids and diols, method for preparing same, and use thereof in cosmetics...
A compound of formula (I): R'--O-A-O--R'', in which R' and R'' are a hydrogen atom or a monovalent radical of formula (IIa), or a monovalent radical of formula...
US-9,567,289 Position-specific asymmetric deuterium enriched catecholamine derivatives and medicaments comprising said compounds
Herein described are deuterated catecholamine derivatives of the general Formula (I) wherein R.sub.1 is deuterium, R.sub.2, and R.sub.3 are independently...
US-9,567,288 Crystalline salts of (Z)-O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate
Here provided are a salt of Z)--O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate with an L-lysine addition in crystalline form and methods of making and...
US-9,567,287 Compound for organic light-emitting diode and organic light-emitting diode including the same
A compound represented by Formula 1 below may be used in an organic light emitting diode. Additionally, in some embodiments, an organic light-emitting diode...
US-9,567,286 Flavor and fragrance formulation (III)
The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific...
US-9,567,285 Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays
The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to the use thereof for optical,...
US-9,567,284 Hexaester of mono-formal bis pentaerythritol
To provide hexaester of bispentaerythritol monoformal, which is a mixed ester of bispentaerythritol monoformal represented by the following formula (I), and...
US-9,567,283 Method for separating mandelic compounds in salified form and use of same for preparing aromatic aldehyde
The invention describes a method for separating a mandelic compound in salified form from an aqueous reaction medium resulting from the condensation reaction of...
US-9,567,282 Production of acetic acid with high conversion rate
A process for producing acetic acid comprising the steps of reacting carbon monoxide and at least one of methanol and a methanol derivative in a first reactor...
US-9,567,281 4-acylaralkylphenols and derivatives thereof
4-Aralkylphenols and derivatives thereof expressed by general formulas (6) and (7) are useful for producing trisphenols. ##STR00001##
US-9,567,280 Preparation of hop acids and their derivatives
A method for preparing a hop acid mixture having an enantiomeric excess of a (+)-tetrahydro-.alpha.-acid is disclosed. In the method, a racemate of a...
US-9,567,279 Methods for oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols
A method of producing alpha-tocotrienol quinone or a stereoisomer thereof, the method comprising selective opening of alpha-tocotrienol chroman to...
US-9,567,278 Production of para-propylbenzaldehyde
The present invention is a process for preparing a 4-alkylbenzaldehyde (para-alkylbenzaldehyde). An alkylbenzene, solvated in a solvent comprising at least one...
US-9,567,277 Reagent for enhancing generation of chemical species
A reagent that enhances acid generation of a photoacid generator and composition containing such a reagent is described.
US-9,567,276 Chromium-free hydrogenation of hydroformylation mixtures
The invention relates to a process for the preparation of alcohols by hydrogenation of aldehydes, in which use mixture comprising at least one aldehyde and at...
US-9,567,275 Process for preparing C.sub.3-6(hydro)fluoroalkenes by dehydrohalogenating C.sub.3-6 halo(hydro)fluoroalkanes...
The invention relates to a process for preparing a C3-6 (hydro)fluoroalkene comprising dehydrohalogenating a C3-6 hydro(halo)fluoroalkane in the presence of a...
US-9,567,274 Process for the manufacture of 2-chloro-1,1,1,2-tetrafluoropropane by liquid phase fluorination of...
Process of catalytic fluorination in liquid phase of product 2-chloro-3,3,3-trifluoropropene into product 2-chloro-1,1,1,2-tetrafluoropropane, with an ionic...
US-9,567,273 Process for preparing alkylate comprising an improved solids removal step
The present invention relates to a process for preparing alkylate comprising the subsequent steps (a), (b) and (c): (a) an alkylation step, wherein in a...
US-9,567,272 FCC process with a dehydrogenation zone for max propylene production
A process is presented for the production of light olefins. The process provides for the separation of the effluent stream from a catalytic cracking process...
US-9,567,271 Process for the recovery of paraffins from an isomerization effluent
A process for the recovery of C.sub.4 hydrocarbons from a C.sub.5/C.sub.6 isomerization zone. A portion of the effluent stream from the C.sub.5/C.sub.6...
US-9,567,270 Process for producing exo-tetrahydrodicyclopentadiene
A process for isomerizing endo-hydrogenated dicyclopentadiene to form the corresponding exo-isomer using a stable, pumpable liquid aluminum halide catalyst...
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