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Patent # Description
US-9,566,315 Normalization of the enterohepatic circulation in animals with a chimeric humanized liver
Methods of normalizing bile acid production in a mouse engrafted with human hepatocytes by the administration of human FGF19 are disclosed. Also disclosed is a...
US-9,566,314 Extracellular vesicles comprising recombinant lysosomal transmembrane protein
The present invention provides compositions and methods for providing factor replacement therapy. In particular, the present invention provides replacement...
US-9,566,313 Method of treating peripheral vascular diseases using IL-18 inhibitors
The invention relates to the use of an inhibitor of IL-18 in the preparation of a medicament for treatment and/or prevention of peripheral vascular diseases....
US-9,566,312 Cyclic peptides and use as medicines
The present invention provides a compound of formula I; ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3,...
US-9,566,311 Pharmaceutical composition
The present invention relates to pharmaceutical compositions having improved stability.
US-9,566,310 Methods of treating muscular dystrophy
Disclosed herein are .alpha.7.beta.1 integrin modulatory agents and methods of using such to treat conditions associated with decreased .alpha.7.beta.1 integrin...
US-9,566,309 Compositions for treatment of cancer-related fatigue
Disclosed are compositions containing extracts of (a) Panax ginseng C. A. Mayer, (b) Zingiber officinale, (c) Echinacea angustifolia and (d) Silybum marianum or...
US-9,566,308 Preparation, process and a regenerative method and technique for prevention, treatment and glycemic control of...
A medicinal preparation, a process, a nutritional composition and regenerative and insulin potentiating method for humans and also for mammals for prevention,...
US-9,566,307 Pharmaceutical composition
A pharmaceutical composition contains a coxsackievirus A11 type that infects cancer cells or an echovirus 4 type that infects cancer cells. The coxsackievirus...
US-9,566,306 Formulations and methods for treatment of wounds and inflammatory skin conditions
The disclosure of the present application includes topically administrable compositions and methods for treating wounds and inflammatory conditions of the skin...
US-9,566,305 Therapeutic compositions and methods for addressing physiological stresses and aging
Therapeutic compositions for addressing physiological stresses and aging include an immune modulator and one or more adaptogenic nutrients. Some non-limiting...
US-9,566,304 Pharmaceutical composition for preventing or treating cancers comprising dendritic cells with Dab2 gene silenced
Provided is a pharmaceutical composition for preventing or treating cancer, and more particularly, a pharmaceutical composition for preventing or treating...
US-9,566,303 Iron-fiber composition, preparation and uses thereof
Compositions comprising ferrous and/or ferric iron compounds and fiber in a complex, methods for preparing such compositions of matter, and the use thereof for...
US-9,566,302 Composition comprising mixed metal compounds and xanthan gum
The present invention provides a composition comprising (i) a mixed metal compound containing at least one trivalent metal selected from iron (lll) and aluminum...
US-9,566,301 Compositions and methods for treating or preventing diseases associated with oxidative stress
Methods and compositions for treating various indications by lessening oxidative stress in a patient are provided. A pharmaceutical composition comprises...
US-9,566,300 Method, composition and package for bowel cleansing
The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When...
US-9,566,299 Oral pharmaceutical composition of aliphatic amine polymer or salts thereof
The present invention relates to an oral pharmaceutical composition of aliphatic amine polymer or salts thereof comprising mixture of water and organic...
US-9,566,298 Method for treating acute kidney injury
The present invention provides methods for treating acute kidney injury through introduction of one or more drag reducing polymers, oligomers, and/or monomers,...
US-9,566,297 Methods and compositions for inhibiting cellular proliferation and surgical adhesion
The present invention provides compositions and methods to inhibit fibrosis and scarring associated with surgery. The present invention relates to the discovery...
US-9,566,296 Multi-layered anti-adhesion device
Compositions and methods are provided for preparing an adhesion barrier in the form of a foldable or flexible biodegradable polymer matrix that effectively...
US-9,566,295 GNAQ targeted dsRNA compositions and methods for inhibiting expression
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a G-alpha q subunit (GNAQ) of a heterotrimeric G gene, and methods of using the...
US-9,566,294 Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis
The present invention relates to the identification of a novel role of CXCR-4 in cell transformation and aberrant cellular proliferation. In particular, the...
US-9,566,293 Oral delivery of therapeutically effective LNA oligonucleotides
The invention provides for LNA oligomers, for the treatment of a metabolic or liver disorder, wherein the LNA oligomer is administered orally in a unit dose of...
US-9,566,292 Methods and compositions for modulating an immune response with immunogenic oligonucleotides
This document relates to compositions and methods for modulating an immune response. For example, compositions of immunostimulatory CpG oligonucleotides derived...
US-9,566,291 Nutritional composition comprising indigestible oligosaccharides
The present invention provides a method and composition for the treatment and/or prevention of respiratory tract infection and/or respiratory tract infection...
US-9,566,290 Boron-containing small molecules
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal...
US-9,566,289 Boron-containing small molecules
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal...
US-9,566,288 High-purity phospholipids
Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids, are disclosed....
US-9,566,287 Pharmaceutical composition of doxycycline with reduced food effect
The present invention relates to a once daily pharmaceutical composition comprising doxycycline and one or more pharmaceutically acceptable excipients, wherein...
US-9,566,286 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid
The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analog and a corticosteroid, and its use...
US-9,566,285 Methods and materials for reducing suppression of immune function
This document provides methods and materials involved in reducing suppression of immune function in mammals. For example, methods and materials for (a)...
US-9,566,284 Agents and methods for treating ischemic and other diseases
This invention relates to methods of screening for modulators of mammalian cell injury cause by TRPM7 gene and protein activity, compounds that modulate TRPM7...
US-9,566,283 Compositions and methods for inhibition of the JAK pathway
Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in...
US-9,566,282 Methods for identifying and validating selective anti-cancer stem cell agents
Described are methods of treating a cancer comprising administering to a subject in need thereof an effective amount of a dopamine receptor (DR) antagonist. The...
US-9,566,281 MEK inhibitors in the treatment of virus diseases
The present invention relates to MEK inhibitors that are capable of displaying one or more beneficial therapeutic effects. The MEK inhibitors can be used in the...
US-9,566,280 Combination therapies and methods of use thereof for treating cancer
Pharmaceutical compositions including an effective amount of an antiandrogen or androgen antagonist in combination with a Plk inhibitor and methods of use...
US-9,566,279 Hematological treatments based on levomefolate
Methods of treating hematological disorders including macrocytosis, and for decreasing hematological markers such as mean corpuscular volume, homocysteine and...
US-9,566,278 Protein kinase C inhibitors and uses thereof
This disclosure concerns compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders...
US-9,566,277 Methods of using phthalazinone ketone derivatives
A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use...
US-9,566,276 Phthalazinone derivatives
Compounds of the formula (I): ##STR00001## wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NR.sup.X or...
US-9,566,275 Compositions for treating CMT and related disorders
The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
US-9,566,274 Methods for enhancing the release and absorption of water insoluble active agents
Methods for enhancing the release and/or absorption of poorly water soluble active agents are described herein. The method involves dissolving, melting, or...
US-9,566,273 Nicotinic attenuation of CNS inflammation and autoimmunity
The present invention relates to methods of treating and/or ameliorating the severity of inflammation and autoimmunity in the central nervous system (CNS). In...
US-9,566,272 Compositions and methods for treating diseases of the nail
Methods and compositions for treating disorders of the nail and nail bed. Such compositions contain a vehicle in which all components of the composition are...
US-9,566,271 Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in...
US-9,566,270 Methods for treating irritable bowel syndrome (IBS)
The present invention provides new methods and kits for treating IBS; treating IBS in females; treating IBS in older subjects; and treating IBS in non-white...
US-9,566,269 Modified release compositions of epalrestat or a derivative thereof and methods for using the same
Modified release pharmaceutical compositions of epalrestat are provided. Methods of manufacturing the tablets and treating various diseases and conditions,...
US-9,566,268 Solid dispersions of insoluble drug and preparation method thereof
The present invention relates to a solid dispersion characterized in that it comprises carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester as an...
US-9,566,267 Biostable, multipurpose, microbicidal intravaginal devices
Biostable, multipurpose, microbicidal intravaginal devices in the form of rings, ringed-meshes, sponges, or diaphragms for use by women and condoms for use by...
US-9,566,265 Carbazole compounds and therapeutic uses of the compounds
Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable...
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