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Patent # Description
US-9,567,619 Non-caloric sweeteners and methods for synthesizing
Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebaudioside...
US-9,567,618 Microorganisms and methods for producing substituted phenols
The present invention is concerned with methods for producing vanillin, feroyl-CoA, ferulic acid, coniferyl aldehyde and/or coniferyl alcohol. Also, the...
US-9,567,617 Mutant xylanase, manufacturing method and use therefor, and method for manufacturing saccharified lignocellulose
What is aimed at is provision of an inexpensive and efficient saccharification method for lignocellulose using a thermostable xylanase and provision of a mutant...
US-9,567,616 Process for producing target substance by fermentation
A target substance can be efficiently produced by culturing, in a medium, a coryneform bacterium in which the activity of a PTS protein relating to fructose...
US-9,567,615 Variant thioesterases and methods of use
The present invention relates to variant thioesterases and their use in plants, e.g., to increase enzymatic activity and to promote increased production of...
US-9,567,614 Genetically engineered bacterial cell having enhanced activity of GlnD or GlnK and method of producing organic...
A genetically engineered bacteria cell having an enhanced activity of GlnD or GlnK, and a method of producing succinic acid by using the genetically engineered...
US-9,567,613 Recombinant microorganism having enhanced butanol producing ability and method for producing butanol using the same
The present invention relates to a microorganism having an acetyl CoA biosynthesis pathway and a butyryl CoA biosynthesis pathway; the microorganism being a...
US-9,567,612 Corn degerming ethanol fermentation processes
The invention presents novel corn fermentation processes that remove the oil-rich fraction either during or after fermentation instead of before fermentation as...
US-9,567,611 Two-stage anaerobic digestion systems wherein one of the stages comprises a two-phase system
Low cost, efficient two-stage anaerobic digestion systems for the production of biogas (e.g. methane) are provided. During the first stage, biogas is produced...
US-9,567,610 Use of Botrytis cinerea for obtaining gold nanoparticles
The present invention is related to the use of Botrytis cinerea strains, its spores, hyphae mycelium, sclerotia, intra and/or extracellular organic molecules,...
US-9,567,609 Compositions for linking DNA-binding domains and cleavage domains
Disclosed herein are compositions for linking DNA binding domains and cleavage domains (or cleavage half-domains) to form non-naturally occurring nucleases....
US-9,567,608 Methods of nuclease-based genetic engineering
The present invention relates to genetic techniques employing the direct ligatation of an external DNA fragment generated in situ by the same ZFNs that target...
US-9,567,607 Adeno-associated virus serotype I nucleic acid sequences, vectors and host cells containing same
The nucleic acid sequences of adeno-associated virus (AAV) serotype 1 are provided, as are vectors and host cells containing these sequences and functional...
US-9,567,606 Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom
The present invention provides vectors that contain and co-express in vivo or in vitro immunogenic polypeptides or antigens together with an OX40L polypeptide,...
US-9,567,605 Methods for use of a specific anti-angiogenic adenoviral agent
Anti-angiogenic adenovirus vectors, and therapeutic use thereof are provided, and more particularly, but not exclusively, clinical protocols for treatment of...
US-9,567,604 Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing
Methods for increasing specificity of RNA-guided genome editing, e.g., editing using CRISPR/Cas9 systems, using truncated guide RNAs (tru-gRNAs).
US-9,567,603 Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
Methods for increasing specificity of RNA-guided genome editing, e.g., editing using CRISPR/Cas9 systems.
US-9,567,602 Combined use of CRY1Ca and CRY1Fa proteins for insect resistance management
The subject invention includes methods and plants for controlling lepidopteran insects. The plants comprise a Cry1Fa insecticidal protein and a Cry1Ca...
US-9,567,601 Photosynthetic resource use efficiency in plants expressing regulatory proteins
Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer...
US-9,567,600 Modification of flavonoid biosynthesis in plants
The present invention relates to nucleic acids encoding flavonoid biosynthetic enzymes, flavonoid-regulating transcription factors and a flavonoid-specific...
US-9,567,599 Modification of flavonoid biosynthesis in plants
The present invention relates to nucleic acids encoding flavonoid biosynthetic enzymes, flavonoid-regulating transcription factors and a flavonoid-specific...
US-9,567,598 Plant plastid transformation method
Method for heterologous protein production in plant cell plastids comprising introducing into plant cells nucleic acid components that encode heterologous...
US-9,567,597 Ultrasound mediated delivery of substances to algae
Embodiments provided herein generally relate to methods and materials for ultrasound-mediated introduction of exogenous substances into microorganisms. Some...
US-9,567,596 Protease deficient filamentous fungal cells and methods of use thereof
The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.
US-9,567,595 Type II restriction modification system methylation subunit of Alicyclobacillus acidocaldarius
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are...
US-9,567,594 Site-specific incorporation of phosphoserine into proteins in Escherichia coli
Nucleic acids encoding mutant elongation factor proteins (EF-Sep), phosphoseryl-tRNA synthetase (SepRS), and phosphoseryl-tRNA (tRNA.sup.Sep) and methods of use...
US-9,567,593 Method for directional cloning
Described herein are techniques for directional cloning an insert DNA segments into a target vector. The techniques mix the target vector, the insert DNA...
US-9,567,592 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell
In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A)....
US-9,567,591 Generation of human embryonic stem-like cells using intronic RNA
This invention generally relates to a method for developing, generating and selecting human embryonic stem (hES)-like pluripotent cells using transgenic...
US-9,567,590 Method of introducing a mitochondrial genome into a eukaryotic cell mitochondrion
The invention provides transgenomic mitochondria, transmitochondrial cells and organisms, and the materials and methods for making such mitochondria, cells, and...
US-9,567,589 NGF aptamer and application thereof
The present invention provides an aptamer binding to NGF and capable of forming a potential secondary structure represented by the formula (I): ##STR00001## ...
US-9,567,588 Modulation of androgen receptor expression
Certain embodiments are directed to compounds and compositions targeted to human androgen receptor (AR) for inhibiting androgen receptor levels in a cell, which...
US-9,567,587 Antisense modulation of GCCR expression
Provided herein are methods, compounds, and compositions for reducing expression of GCCR mRNA and protein in an animal. Such methods, compounds, and...
US-9,567,586 EpCAM aptamer for detection of cancer stem cells
The present disclosure relates to an RNA aptamer and uses thereof, in particular, an aptamer which specifically bind to EpCAM and which demonstrates superior...
US-9,567,585 Antisense oligonucleotide modulators of serotonin receptor 2C and uses thereof
The present invention provides, among other things, oligonucleotide modulators of human 5'-HT2C receptor (HTR2C) and improved methods and composition for...
US-9,567,584 Oligonucleotide--containing pharmacological compositions and their use
The present invention relates to methods and compositions containing oligonucleotides suitable for administration to humans and other mammals.
US-9,567,583 Method for treating glioma using Tarbp2 expression inhibitor
A method of preventing or treating glioma by inhibiting expression of Tarbp2, which is a novel transcription factor inducing Notch signal activation, and a...
US-9,567,582 RNA interference mediating small RNA molecules
Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using...
US-9,567,581 Selective reactivation of genes on the inactive X chromosome
Methods and compositions for selectively reactivating genes on the inactive X chromosome (Xi) in a locus-specific manner, e.g., genes associated with X-linked...
US-9,567,580 Regulators of NFAT and/or store-operated calcium entry
Embodiments of the inventions relate to modulating NFAT activity, modulating store-operated Ca.sup.2+ entry into a cell and treating and/or preventing...
US-9,567,579 Structure based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamer...
The present invention includes composition and methods for making and using a combinatorial library to identify modified thioaptamers that bind to, and affect...
US-9,567,578 Cell line containing a knockout of the glutamine synthetase (GS) gene and a method of producing target proteins...
The present invention relates to a novel GS (glutamine synthetase) gene knock out transgenic HEK293 (human embryonic kidney 293) cell line and a production...
US-9,567,577 Expression vector comprising a polynucleotide encoding a modified glutamine synthetase and a method for...
The present invention relates to a vector comprising a polynucleotide encoding a modified glutamine synthetase (GS), and a method for preparing a target protein...
US-9,567,576 Strain expressing FRSA and method for producing ethanol using same
The present application relates to a strain expressing the FrsA protein, and a method for producing ethanol using the same. The FrsA of the present application...
US-9,567,575 Phage twort endolysin CHAP domain is lytic for Staphylococcus aureus
Increases in antibiotic resistant strains of Staphylococcus aureus have elicited efforts to develop novel antimicrobials. One potential treatment includes lytic...
US-9,567,574 Polypeptides having glucoamylase activity and polynucleotides encoding same
The present invention provides isolated polypeptides having glucoamylase activity, catalytic domains, and polynucleotides encoding the polypeptides, catalytic...
US-9,567,573 Genome editing of a Rosa locus using nucleases
Disclosed herein are methods and compositions for genome editing of a Rosa locus, using fusion proteins comprising a DNA binding domain and a cleavage domain or...
US-9,567,572 Manufacture of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase and uses thereof
This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and...
US-9,567,571 Hepatitis B virus mutant, mutant amplification kit and use thereof
The present invention relates to the field of biotechnology, and discloses a hepatitis B virus mutant, a mutant amplification kit and use thereof. The HBV...
US-9,567,570 Assays using a multi-divot platform and multi-source, multi-cell type clusters
Described herein are 3-dimensional clusters of reaggregated cells comprising cells reaggregated from at least two different cell sources, such as different cell...
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