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Patent # Description
US-9,567,369 Method of treating metastatic cancer
A method of treating metastatic cancer, comprising the steps of (a) treating a metastatic cancer patient with an isolated therapeutic Cystatin C peptide, and...
US-9,567,368 Peptide tyrosinase activators
Peptides that increase melanin synthesis are provided. These peptides include pentapeptides YSSWY (SEQ ID NO: 1), YRSRK (SEQ ID NO: 2), and their variants. The...
US-9,567,367 Synthetic peptides for treatment of bacterial infections
Disclosed are peptides and methods for the treatment of bacterial infections and associated inflammation. Effective doses and treatment protocols are disclosed.
US-9,567,366 Water-based prolamin compositions, methods of making water-based prolamin compositions, and applications thereof
The invention relates to water-based prolamin (e.g., zein) compositions and to methods of making water-based prolamin compositions. The compositions may be used...
US-9,567,365 Method for separating estrogen from placenta
The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body...
US-9,567,364 Nucleotide and/or oligonucleotide and preparation process thereof
Nucleotide and/or oligonucleotide represented by formula (1) and the liquid phase synthesis process thereof. The present invention provides a liquid phase...
US-9,567,363 Certain compounds, compositions and methods
The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of...
US-9,567,362 Compounds and methods for treating bacterial infections
The present invention encompasses compounds and methods for treating urinary tract infections.
US-9,567,361 Use of purified 2'-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
US-9,567,360 Process for production of precipitated lignin from black liquor and precipitated lignin produced by the process
The present invention relates to a process tor the production of precipitated lignin from black liquor wherein the process comprises the steps of providing a...
US-9,567,359 Solvent self-reactions with P(CN)3 to produce films and particles of C3N3P
A material with the empirical formula C.sub.3N.sub.3P is made by polymerizing P(CN).sub.3 in a polar aprotic solvent such as acetonitrile, by heating,...
US-9,567,358 Methods of treatment using N-(3-fluorophenyl)-2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-quina- ...
Quinazoline derivatives of formula (I): ##STR00001## wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms;...
US-9,567,357 Biocompatible, biomimetic ampholyte materials
New ampholyte biomaterial compounds containing ampholyte moieties are synthesized and integrated into polymeric assemblies to provide hydrophilic polymers...
US-9,567,356 Method for the fractionation of phospho-lipids from phospholipid-containing material
The present invention relates to a counter-current extraction process involving a plurality of mixing and separation stages for fractionating a ...
US-9,567,355 Hepatitis C inhibitors and uses thereof
This disclosure relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and...
US-9,567,354 Amino acid-modified silane compounds and making method
Novel amino acid-modified silane compounds having a weakly acidic amino group and a weakly basic carboxyl group are useful as a surface treating agent or...
US-9,567,353 Sol-gel precursors and products thereof
The present invention provides a generalizable single-source sol-gel precursor capable of introducing a wide range of functionalities to metal oxides such as...
US-9,567,352 Tris(trimethyl siloxy)silane vinylic monomers and uses thereof
The invention provides a TRIS-containing vinylic monomer which comprises one sole (meth)acryloyloxy group and a tris(trimethylsiloxy)silyl group covalently...
US-9,567,351 Heterophasic copolymers
A heterophasic polypropylene resin comprising a polypropylene homopolymer matrix phase (A) and an ethylene-propylene copolymer phase (B) dispersed within the...
US-9,567,350 Process for the preparation of chelated compounds
The present invention generally relies on a process for the preparation of chelated compounds, comprising the selective interaction between a solid matrix and a...
US-9,567,349 Preparing method of Ag nano-particle and hydrophobic spherical Ag nano-particle prepared using the same
Provided is a preparing method of an Ag nano-particle for mass-producing Ag nano-particles, the method including: performing a first reaction of a reaction...
US-9,567,348 Substituted pyrazolo[1,5-a]pyrimidines as Syk inhibitors
Certain pyrazolo[1,5-a]pyrimidines: ##STR00001## or pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof are provided herein....
US-9,567,347 Use of small molecule inhibitors targeting the interaction between RAC GTPase and p67.sup.(phox)
Inhibitors of p67.sup.phox protein are provided herein, as well as pharmaceutical compositions and methods relating thereto.
US-9,567,346 Biotin derivatives
Biotin derivatives, methods of using the biotin derivatives and kits comprising the biotin derivatives.
US-9,567,345 Pharmaceutically active pyrazolo-triazine derivatives
The present invention relates to pyrazolo[1,5-a][1,3,5]triazine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as...
US-9,567,344 Molecular containers and methods of making and using same
Acyclic CB[n]-type compounds, methods of making such compounds, and uses of the compounds. For example, these compounds can be used as nanocontainers to...
US-9,567,343 Aza-bicyloalkyl ethers and their use as alpha7-nachr agonists
The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, ##STR00001## wherein X is CH.sub.2 or a single bond; Y is a group of formula ...
US-9,567,342 Certain protein kinase inhibitors
Disclosed herein are protein kinase inhibitors, more particularly novel pyrimidine derivatives and pharmaceutical compositions thereof, and method of use thereof.
US-9,567,341 Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists
Disclosed are chemical entities of formula I: ##STR00001## wherein X, Y, Z, R.sup.1, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are defined herein, as NR2B subtype...
US-9,567,340 Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
A compound of formula I: ##STR00001## or a pharmaceutically acceptable salt or solvate thereof.
US-9,567,339 Primary carboxamides as BTK inhibitors
The invention provides compounds of Formula (I) ##STR00001## pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and...
US-9,567,338 Pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma ligands
Pyrazolo[3,4-d]pyrimidine compounds having a great affinity for sigma receptors, especially sigma-1 receptors, as well as a process for preparing these...
US-9,567,337 Process methods for phosphatidylinositol 3-kinase inhibitors
A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound...
US-9,567,336 Conjugated TLR7 and/or TLR8 and TLR2 agonists
A conjugated compound of formula Q-Z--R.sup.4 wherein Q is a TLR7 and/or TLR8 agonist and Z--R.sup.4 is a TLR2 agonist, and the uses thereof in the treatment of...
US-9,567,335 Process for sodium salt of (2S, 5R)-2-carboxamido-7-oxo-6-sulfooxy -1,6-diaza-bicyclo[3.2.1]octane
A process for preparation of a sodium salt of (2S,5R)-2-carboxamido-7-oxo-6-sulfooxy-1,6-diaza-bicyclo[3.2.1]octane is disclosed which is comprising the...
US-9,567,334 Quinolone derivatives as fibroblast growth factor receptor inhibitors
Compounds that are Fibroblast Growth Factor Inhibitors (FGFR) and are therefore useful for the treatment of diseases treatable by inhibition of FGFR are...
US-9,567,333 Triazolopyridyl compounds as aldosterone synthase inhibitors
This invention relates to triazolopyridyl compounds of the structural formula: ##STR00001## or their pharmaceutically acceptable salts, wherein the variable...
US-9,567,332 Process for the preparation and purification of apixaban
The present invention provides a process for the preparation and purification of apixaban.
US-9,567,331 Pyridopyrimidinone inhibitors of viruses
Provided herein are novel small molecule pyridomyrimidone viral inhibitor agents of Formula (I), such as ...
US-9,567,330 Azabenzimidazole derivative having AMPK-activating activity
Disclosed is a compound which is useful as an AMPK activator. A compound represented by formula: ##STR00001## or a pharmaceutically acceptable salt thereof,...
US-9,567,329 High penetration prodrug compositions of 1H-imidazo[4,5-c]quinolin-4-amines and ...
The invention provides compositions of novel high penetration compositions (HPC) or high penetration prodrugs (HPP) of 1H-imidazo[4,5-c]quinolin-4-amines and ...
US-9,567,328 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response
The present invention provides a compound, that is a 1-({halo-2-[(2-hydrocarbyl or substituted hydrocarbyl)oxy]phenyl}methyl)-(fused bicyclic nitrogen...
US-9,567,327 Imidazo[1,2-a]pyridine derivatives as modulators of the 5-HT.sub.2A serotonin receptor useful for the treatment...
rmidazo[1,2-.alpha.]pyridine derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT.sub.2A serotonin...
US-9,567,326 Pyrimidine compounds for the treatment of cancer
Described are compounds of Formula I or Formula II: wherein: ring A is a 5- or 6-membered heteroaryl group; dashed lines are optional double bonds; X is N or O;...
US-9,567,325 Carboxamide compounds and their use as calpain inhibitors
The present invention relates to novel carboxamide compounds and their use as a medicament. The carboxamide compounds are inhibitors of calpain (calcium...
US-9,567,324 Substituted nicotinamide derivatives as kinase inhibitors
The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit...
US-9,567,323 Substituted anilines as CCR(4) antagonists
Aniline compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection...
US-9,567,322 Substituted tetrahydropyrans and method of use
Compounds of formula (I) ##STR00001## and pharmaceutically acceptable salts or radiolabelled forms thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4,...
US-9,567,321 Aromatic monomers deriving from glycerol units, process for their preparation and use thereof for the...
Monomers having formula (I) and process for their synthesis which comprises the etherification reaction of a halogen-derivative (Z.dbd.Cl, Br, I) having formula...
US-9,567,320 Pyridazinone-amides derivatives
The present invention relates to compounds of formula (I) wherein R1, Ra, Rb and Z have the meaning given in claim 1, and their use in the prophylaxis and...
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