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Method of co-expressing galactosyltransferase and a glycoprotein in a
transgenic plant cell and sialylating the...
A method for the secretory production of a glycoprotein having a human-type sugar chain, comprising a step of introducing a gene of an enzyme capable of...
Multi-stage process for production of immune modulator
Immune function of an animal can be modulated by administration of a composition that includes algae meal or beta glucan. The algae meal can be made by growing...
Auto-indicible expression system, and the use thereof for producing useful
metabolites using a bacterium of the...
The present invention describes a method for producing a useful metabolite using a bacterium of the family Enterobacteriaceae, particularly a bacterium...
Production of fatty acids by heterologous expression of gene clusters from
The invention relates to a process for producing one or more polyunsaturated fatty acids by means of heterologous gene expression comprising the steps of...
Paenibacillus sp. CAA11 capable of saccharification and fermentation of
cellulose and transformed strain thereof
The present disclosure relates to a novel strain capable of saccharifying and fermenting biomass-derived cellulose and a recombinant strain thereof with...
Method of organic acid fermentation by rumen fluid using
cellulose-containing waste matter
The present application provides a method for producing organic acid, such as acetic acid, propionic acid, butyric acid, or another high-quality raw material...
Process comprising sulfur dioxide and/or sulfurous acid pretreatment and
The disclosure provides a process for producing a fermentation product from a lignocellulosic feedstock. The process describes soaking a lignocellulosic...
Methods and compositions for prevention or treatment of a disease
Methods and compositions for treatment of a genetic disease are provided.
Cell-targeting nanoparticles comprising polynucleotide agents and uses
A method of generating a particle is disclosed, the particle being for delivery of a polynucleotide to a target cell. The method comprises (a) contacting the...
Enhanced nucleic acid constructs for eukaryotic gene expression
The present invention provides polynucleotide vectors for high expression of heterologous genes, and methods for constructing such vectors. Some vectors further...
Methods and compositions for producing male sterile plants
Methods of making a targeted modification in a male fertility gene in the genome of a plant are disclosed. The methods involve contacting a plant cell with an...
DGAT genes for increased seed storage lipid production and altered fatty
acid profiles in oilseed plants
Polynucleotide sequences encoding diacylglycerol acyltransferase genes and the use of these acyltransferases for increased seed storage lipid production and...
Engineered biomass with increased oil production
The present invention relates to a genetically modified plant having an increased amount of oil in its green biomass as compared to the oil in the green biomass...
Microsomal .omega.6 oleate desaturases
The present invention relates to the field of plant molecular biology, more particularly Jatropha microsomal co6 oleate desaturases. The present invention also...
Plant seeds with altered storage compound levels, related constructs and
methods involving genes encoding PAE...
This invention is in the field of plant molecular biology. More specifically, this invention pertains to isolated nucleic acid fragments encoding PAE or...
Transgenic guayule for enhanced isoprenoid production
The present invention relates to transgenic guayule plants that produce increased amounts of rubber uses thereof.
Methods for increasing the anthocyanin content of citrus fruit
Methods are provided for making a citrus plant that is capable of producing fruit with increased levels of anthocyanins in the fruit when compared to a citrus...
Methods and means to modify a plant genome at a nucleotide sequence
commonly used in plant genome engineering
Methods and means are provided to modify in a targeted manner the plant genome of transgenic plants comprising chimeric genes wherein the chimeric genes have a...
Polynucleotides and polypeptides for increasing desirable plant qualities
Polynucleotides and isolated polypeptides, nucleic acid constructs comprising the isolated polynucleotides, transgenic plants expressing same and methods of...
Simultaneous site-specific integrations of multiple gene-copies in
The invention relates to a method for the simultaneous integration of two or more copies of a polynucleotide of interest into the chromosome of a fungal host...
Bacteria and the uses thereof
The present invention relates to novel bacteria and the uses thereof. The invention particularly relates to bacteria having a metabolic pathway ratio between...
Systems and methods for the secretion of recombinant proteins in gram
Disclosed herein are systems and methods for producing recombinant proteins utilizing mutant E. coli strains containing expression vectors carrying nucleic...
Regulated genetic suicide mechanism compositions and methods
Embodiments of the present invention relates to the incorporation and use of a regulated genetic suicide mechanism for use in the improved purification of...
RNAi agent for inhibition of Chikungunya virus
Provided herein are RNAi agents for inhibition of Chikungunya virus. The present disclosure provides RNAi agents for inhibition of Chikungunya virus,...
MicroRNA compounds and methods for modulating miR-122
Described herein are compositions and methods for the inhibition of miR-122 activity. The compositions have certain nucleoside modifications that yield potent...
Methods and compositions for modulating apolipoprotein (a) expression
Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a)...
Serapina1 iRNA compositions and methods of use thereof
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit...
Selective inhibition of polyglutamine protein expression
The present invention relates to the selective inhibition of protein expression of CAG repeat-related disease proteins such as Huntingtin Disease Protein and...
Screening method for peptide binding to target molecule in pH-dependent
An object of the present invention is to provide molecules that bind to a target molecule in a pH dependent manner and a screening method for selecting such...
Enzymatic encoding methods for efficient synthesis of large libraries
Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent...
DNA restriction library tagging and analysis
The disclosed methods in the application relates to making an adapter-tagged restriction library. The library or libraries created with the disclosed methods...
Innovative discovery of therapeutic, diagnostic, and antibody compositions
related to protein fragments of...
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof,...
Stabilization of thermolysin in aqueous solution
The present invention deals with the proteolytic enzyme thermolysin which tends to be unstable in aqueous solution. The invention provides methods and...
Cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717
and uses thereof
A cold-adapted protease derived from Pseudoalteromonas arctica PAMC 21717 or a recombinant cold-adapted protease obtained by expressing a gene encoding the...
Lysosomal protein targeting sequence and therapeutic applications of same
The present disclosure relates to methods of treating diseases states such as lysosomal storage diseases and/or neurodegenerative diseases. Also disclosed are...
Method and kits for repairing nucleic acid sequences
Methods and kits for DNA repair are provided. The methods and kits described herein repair multiple types of DNA damage. The kit may include a plurality of...
Monoterpene glycosyltransferase originating from hop and method for using
The object of the present invention is to provide Humulus lupulus-derived monoterpene glycosyltransferase and a method for producing a monoterpene glycoside by...
Influenza virus reassortment method
Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.
Cell therapy: a method and a composition for treating diabetes
A method of obtaining beta-islet cells from pancreases of rabbits and a composition for transplantation (xenografts or xenotransplants) of beta-islet cells...
Hematopoietic precursor cell production by programming
The invention generally regards methods for providing hematopoietic cells and precursors of hematopoietic cells from a variety of cell sources, such as...
Megakaryocyte and platelet production from stem cells
Methods for obtaining purified populations of megakaryocytes and platelets by ex vivo culture of stem cells are provided herein.
Methods for reducing and/or preventing excessive cellular apoptosis
The invention is directed to methods for reducing the number of apoptotic cell deaths in a population of cells undergoing excessive cellular apoptosis. The...
Neural stem cell having increased passage ability, method for
manufacturing neural stem cell having said...
The present invention provides a neural stem cell having increased passage ability and a method for manufacturing a neural stem cell having increased passage...
Endometrial polyp stem cell
An endometrial polyp stem cell is disclosed in the present invention. The endometrial polyp stem cell is isolated from an endometrial polyp tissue, expresses...
A method for determining the effect of a plurality of culture conditions on a cell, comprising the steps of: a) providing a first set of groups of cell units...
Generation of neural stem cells from human trophoblast stem cells
Provided herein are isolated neural stem cells. Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the...
Method for producing three-dimensional monolithic microfluidic devices
A method is described for producing a microfluidic device (19), which comprises the phases of producing a three-dimensional template (15) of geometry equal to...
Methods of generating corneal cells and cell populations comprising same
A method of generating a population of corneal epithelial cells is disclosed. The method comprises culturing human pluripotent stem cells in corneal...
Schistose microfibrillated article for cell growth
The present invention relates to culturing cells utilizing a matrix of microfibrillated thermoplastic polymeric materials. More specifically, the present...
Cryoprotectants for freeze drying of lactic acid bacteria
The present invention comprises the discovery and development of an effective cryoprotectant composition, without containing skim milk or any other...