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A therapeutic topical composition comprising achillea millefolium (yarrow) extract, aloe vera, arnica montana flowers, annatto seed extract, boswellia serrate...
Dietary supplements for reducing cholesterol levels
The disclosure is generally directed to methods and compositions for reducing blood cholesterol levels, and more particularly to dietary supplements for...
Composition and method of treating actinic purpura
The present invention is a composition and method of treatment for actinic purpura, skin disorders, and skin conditions in general through topical systematic...
Sandalwood oil and its uses related to clostridium infections
Provided herein are methods of using therapeutically effective compositions of sandalwood oil to treat, prevent or reduce the recurrence of Clostridium infections.
Pharmaceutical compositions containing pediococcus and methods for
reducing the symptoms of gastroenterological...
The invention provides a method and composition for ameliorating or reducing the symptoms, signs, and markers and for the treatment of irritable bowel syndrome,...
Process for the therapeutic management of diarrhea predominant irritable
bowel syndrome using Bacillus...
The present invention discloses a process for the therapeutic management of diarrhea predominant irritable bowel syndrome in humans comprising the oral...
Postpartum cells derived from placental tissue, and methods of making and
using the same
Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions...
Human amniotic fluid preparation having long-term stability
Methods of preparing sterile de-cellularized human amniotic fluid that is amenable for long-term storage without loss of biological functions have been...
In vivo iron labeling of stem cells and tracking these labeled stem cells
after their transplantation
Intravenous ferumoxytol is used to effectively label mesenchymal stem cells (MSCs) in vivo and is used for in vivo tracking of stem cell transplants with...
Encapsulated kidney tissue
Provided are therapeutic implants comprising renal tissue encapsulated within a polymer bead. Also disclosed are methods for treating a disease state in a...
Methods for enhancing the effect of EGCg on mitigating skeletal muscle
Disclosed herein are methods for enhancing the efficacy of epigallocatechin gallate ("EGCg") in mitigating skeletal muscle loss in a subject. Providing EGCg to...
Treatment of macrophage-related disorders
The present invention provides a method of treating a macrophage related disease comprising administering to a subject in need thereof an effective amount of an...
Sodium thiosulfate-containing pharmaceutical compositions
Provided herein are pharmaceutically acceptable sodium thiosulfate and pharmaceutical compositions thereof. Also provided herein are methods for determining the...
Use of nitrite salts in treating tissue damage
Methods of treating a subject who has an tissue damage or who is at risk for tissue necrosis are disclosed. Also disclosed are methods of treating a subject who...
Direct compression polymer tablet core
The present invention provides a tablet core which comprises at least about 95% by weight of an aliphatic amine polymer. The invention also provides a method of...
Pharmaceutical composition for relieving pain
The present invention relates to a pharmaceutical composition for relieving pain in a joint disease, including a hyaluronic acid and a pharmaceutically...
Preserved compositions containing hyaluronic acid or a
pharmaceutically-acceptable salt thereof and related methods
The invention provides a composition containing hyaluronic acid (HA) or a pharmaceutically-acceptable salt thereof preserved with a cationic preservative and...
Prebiotic formulations and methods of use
The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal...
Methods of treating cancer
A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition...
Method of producing lipid nanoparticles for drug delivery
What is described is a method for preparing a liposome that efficiently encapsulates a negatively charged therapeutic polymer, e.g., siRNA. The process involves...
Use of uridine and deoxyuridine to treat folate-responsive pathologies
The present invention relates to a pharmaceutical or dietary composition comprising deoxyuridine and a pharmaceutically or dietetically suitable carrier....
Method for treating neurotrauma
The invention relates to a composition comprising: i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; ii) a lipid...
Treatment of cystic diseases
The invention described herein pertains to the treatment of cystic diseases. More particularly, the invention described herein relates to methods for treating...
Iminosugars and methods of treating viral diseases
Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
Inhibition of HIV infection through chemoprophyalxis
A process is provided for protecting a primate host from a self-replicating infection by an immunodeficiency retrovirus. Protection is achieved by administering...
Phosphonate analogs of HIV inhibitor compounds
The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include...
Therapeutic uses of glutathione mimics
A prodrug having antioxidant activity, including a phosphorylated compound having a thiol group. A method of treating oxidative stress by administering a...
Use and application regimen of a pharmaceutical composition containing
levonorgestrel and a COX inhibitor for...
The invention relates to a method of hormonal female controlled "on demand" contraception, in which a pharmaceutical preparation comprising a COX inhibitor and...
Use of estetrol as emergency contraceptive
The present invention relates to a new use of tetrahydroxylated estrogens such as estetrol (1,3,5(10)-estratrien-3, 15.alpha., 16.alpha., 17.beta.-tetrol),...
Prostaglandin and vasoconstrictor pharmaceutical compositions and methods
Compositions containing a prostaglandin agent and a vasoconstrictor agent for ophthalmic applications are provided as well as methods of treating ophthalmic...
Synthesis of chiral
The present invention is directed to novel synthetic methods for preparing a spiro cyclopropyl indolinone compound represented by Structural Formula (A): ...
This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of...
Modulators of TNF-.alpha. signaling
The present invention provides compounds which are modulators of TNF-.alpha. signaling and methods of use thereof for treating a patient having a TNF-.alpha....
Therapeutically active compounds and their methods of use
Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.
Compositions comprising RANK/RANKL antagonists and related compounds for
Disclosed herein are methods of treating pain using RANK/RANKL antagonists.
Methods for treating neurologic disorders
The present invention provides methods for treating a neurological disorder.
Methods and compositions to reduce oxidative stress
The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention...
Inhibitors of syk and JAK protein kinases
The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are...
Heterocyclic compounds as hedgehog signaling pathway inhibitors
This invention relates to novel compounds of formula (I). The compounds of the invention are hedgehog pathway antagonists. Specifically, the compounds of the...
Histamine 4 receptor partial agonists, inverse agonists or antagonists for
use in treating non-autoimmune uveitis
The invention provides a compound which is a histamine 4 receptor antagonist, partial agonist or inverse agonist, for use in the treatment of non-autoimmune...
Peptide-drug conjugates comprising p-aminobenzyl carbamoyl or p-aminobenzolyl carbonate self-immolating linkers are disclosed. The peptide-drug conjugates...
Salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2(1H)-one derivatives
having both muscarinic receptor...
The present invention is directed to crystalline addition salts of (i) 8-hydroxyquinolin-2(1H)-one derivatives and (ii) a dicarboxylic acid or a sulfimide, or a...
Methods of treating obstructive lung diseases using bitter tastants
Described herein are methods for enhancing airway dilation and/or relieving bronchoconstriction, e.g., to treat obstructive lung diseases such as asthma and...
Compounds having muscarinic receptor antagonist and BETA2 adrenergic
receptor agonist activity
Compounds of formula I, defined herein, act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for treating...
Hepatitis B antiviral agents
Provided herein are compounds useful for the treatment of HBV infection in man.
Method for treating/preventing disease using cognitive ability of cerebrum
An object of the present invention is to develop a method of enhancing the cognitive ability of a brain to fundamentally cure a disease. It has been found out...
Decreasing expression level of apoptosis-related genes by treating a human
subject with a nitroxide
Disclosed herein are methods for treating a human subject having a disease associated with an increased level of apoptosis using a nitroxide. Further disclosed...
The present invention relates to a method for producing artificial skin, comprising: adding a matrix metalloproteinase inhibitor and a heparanase inhibitor to...
Prophylactic or therapeutic agent for posterior ocular disease containing
The present invention relates to a prophylactic or therapeutic agent for a posterior ocular disease containing the compound represented by a formula (1), its...
Compositions and methods for treating presbyopia, mild hyperopia, and
The present invention is directed to compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism. The compositions include a...