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Amide derivatives of N-urea substituted amino acids as formyl peptide
receptor like-1 (FPRL-1) receptor modulators
The present invention relates to novel amide derivatives of N-urea substituted amino acids, processes for preparing them, pharmaceutical compositions containing...
Substituted 2-imidazolidinones and 2-imidazolones and their use in the
treatment of cancer
Compounds of formula (I) wherein R.sub.1, R.sub.4, R.sub.8, X and Y as defined herein are provided as useful for the inhibition of certain types of cancer...
Oxytocin receptor antagonist therapy in the luteal phase for implantation
and pregnancy in women undergoing...
The present invention relates to the use of an oxytocin receptor antagonist in females undergoing embryo transfer as part of an assisted reproductive...
Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of...
Compositions containing polysaccharides
The disclosure relates to compositions, preferably in the form of a powder and/or granules, which contain as principal components a first component selected...
Ketone bodies to protect tissues from damage by ionizing radiation
Described herein is the surprising discovery that ketone bodies protect cell and tissues from ionizing radiation. Based on this finding, methods of protecting...
Organic emulsion comprising DHA and EPA
The present invention relates to an emulsion of an oil composition comprising docasoahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which is...
Nanoparticle and polymer formulations for thyroid hormone analogs,
antagonists, and formulations thereof
Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle...
CNS pharmaceutical compositions and methods of use
The present invention is directed to CNS pharmaceutical compositions and methods of use. The pharmaceutical compositions comprise a CNS active agent and...
Antioxidant dietary supplement compositions and methods for maintaining
Compositions and methods for maintaining healthy skin and alleviating skin conditions such as redness, inflammation, irritation and skin aging, as well as for...
Pharmaceutical composition for application to nail
Since treatment effects of conventional external preparations were not satisfactory, it is aimed to provide a novel external preparation that is excellent in...
Compositions and methods for transdermal delivery of hormones and other
The invention provides transdermal delivery systems, medical kits, and methods for using the transdermal delivery systems and kits for medical applications,...
Dosage form for insertion into the mouth
Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, to patients through insertion into the mouth of patient...
Scar tissue dressing
A method of treating scar tissue by applying a composite sheet for delivering therapeutic agents to the skin is disclosed. The composite sheet comprises a...
Timed, pulsatile release systems
A unit multiparticulate dosage form for delivering one or more basic, active pharmaceutical ingredients into the body in need of such medications to achieve...
Film forming hard capsule solution
A film forming solution usable for the manufacture of an allergen free hard capsule containing pullulan polysaccharide, a neutrally charged hydrophilic amide...
Coated controlled release active agent carriers
The present invention relates to carriers for the controlled release of active agents, comprising a core, comprising surface reacted natural or synthetic...
Method for banding hard capsules using hydroxypropylmethyl cellulose
(HPMC) as a base
The present invention provides a banding composition for hard capsules using hydroxypropylmethyl cellulose (HPMC) as a base comprising (1) low viscosity HPMC;...
Controlled release dosage form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of GABA.sub.B receptor agonist contained in the...
Tesofensine and beta blocker combination formulations
The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or...
Microparticles supporting cells and active substances
A method of repairing tissue includes implanting into a patient a therapeutically effective amount of a pharmaceutical composition including microparticles...
Tamper resistant dosage form comprising co-extruded, sequestered adverse
agent particles and process of making same
The present invention relates to co-extruded pharmaceutical compositions and dosage forms comprising an adverse agent, such as an opioid antagonist, which can...
Preparation of a powdery pharmaceutical composition by means of an
The invention relates to a method for the preparation of a powdery pharmaceutical composition comprising a pharmaceutical excipient and a pharmaceutical...
Therapeutic polymeric nanoparticles with mTOR inhibitors and methods of
making and using same
The present disclosure generally relates to therapeutic nanoparticles. Exemplary nanoparticles disclosed herein may include about 1 to about 20 weight percent...
Porous nanoparticle-supported lipid bilayers (protocells) for targeted
delivery and methods of using same
The present invention is directed to protocells for specific targeting of hepatocellular and other cancer cells which comprise a nanoporous silica core with a...
Core-shell nanoparticle including nucleic acid hydrogel and method of
producing the same
The present invention relates to a functional complex particle prepared by filling a nucleic acid hydrogel inside a liposome and a method of producing the same....
Self-emulsifying composition of .omega.3 fatty acid
This invention provides a self-emulsifying composition comprising 50 to 95% by weight in total of at least one compound selected from the group consisting of...
Controlled release delivery system for nasal applications and method of
This invention relates to a gel formulation for nasal administration of a controlled release formulation of hormones to the systemic circulation and/or to the...
Seaweed-derived cosmetic compositions
A cosmetic composition is disclosed for applying to skin. The composition includes a liquid and dispersed in the liquid: any amount or form of fucoidan, any...
Compositions comprising extracts of Bursera simaruba
The present invention relates to a skin care composition comprising an extract of Bursera simaruba seeds and a cosmetically acceptable topical carrier. Such...
Conditioning composition for hair
The present invention is related to an aqueous conditioning composition for hair comprising at least one alkyl ester/amido alkyl amine or alkyl ester/amido...
Clear sunscreen composition for application onto wet or dry skin
The present invention is directed to a composition containing: at least one cross-linked copolymers of acrylic acid and a hydrophobic co-monomer; at least one...
Method and compositions for improving wear of color cosmetics
A composition comprising at least one non-sensitizing pressure sensitive adhesive that is the polycondensate of a silanol endblocked polydimethylsiloxane and a...
Vitamin C composition for use in the prevention and treatment of stretch
marks, radiation dermatitis, and other...
A formulation for a stable ascorbic acid composition which, in a simplified form, is comprised of ascorbic acid in solution with a hygroscopic compound (i.e., a...
Delivery of therapeutic agents by a collagen binding protein
Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic...
Alkyl glycoside-based micellar thickeners for surfactant systems
A rheology modifier which includes a mixture of short and long chain fatty acid esters is suitable for use in liquid surfactant-based compositions. A...
Anhydrous foaming composition
The subject-matter of the present invention is an anhydrous cosmetic composition comprising, in a physiologically acceptable medium: --at least one nonionic...
Compositions and methods for treating hair loss using non-naturally
A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The...
Therapeutic oral composition
Disclosed are therapeutic oral compositions useful in the treatment of a variety of oral disorders, in which the composition can provide blockage of dentinal...
Cosmetic with enhanced collagen I synthesis
A cosmetic including two different systems for procurement of actives in the human skin and enhancing the collagen I synthesis. The cosmetic with enhanced...
Oil in water emulsion cosmetic composition for skin
An oil in water emulsion cosmetic composition for skin, in which vitamin A and its derivatives are stably incorporated and which has superior feeling in use...
Aerosol antiperspirant compositions, products and methods
An aerosol antiperspirant composition is provided. The aerosol antiperspirant composition includes a propellant having a concentration from 70% to 90% by weight...
Pill dispenser with compliance features
A pill dispenser is configured to receive a plurality of different pill types into discrete pill reservoirs, whereby a dose of different pills may be provided...
Time and temperature sensor medication dispenser for hospitals and nursing
homes/monthly personal time
A medication dispenser is described. A plurality of drawers capable of storing medications is arranged in an array. For personal use, each drawer has an...
Cap and bottle
A bottle for dispensing oral care fluid is provided. The bottle can include a body portion comprising a mouth, side surfaces, and a bottom surface arranged to...
Method and apparatus for preparing novel liposome
Disclosed is a method for preparing a liposome formulation. In the disclosed method, a lipid fraction is dissolved in an organic solvent. The solution including...
A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible...
Medicament dispensing system
A medicament dispensing system for orally dispensing medicament to a patient, wherein the system comprises in combination a syringe to extract medicament, an...
Drug delivery device
The drug delivery device (1) connects an syringe barrel (6) and a drug container (2) by means of a closed system, and delivers a drug between the syringe barrel...
Haptic feedback and audible output syringe
A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for "push-pull",...