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Patent # Description
US-9,587,047 Process for the production of bimodal polyethylene in the presence of this catalyst system
The invention relates to a process for the production of bimodal polyethylene in a two-step polymerization process in the presence of a catalyst system...
US-9,587,046 Photocurable composition, protective layer including the same, and encapsulated apparatus including the same
Disclosed are a photocurable composition which includes (A) a photocurable monomer and (B) a monomer represented by Formula 1, and an apparatus including a...
US-9,587,045 Washing and cleaning agent having improved performance
The present invention relates to the use of polyamidohydroxamates in washing and cleaning agents to improve cleaning performance, in particular with regard to...
US-9,587,044 Polypropylene with extreme broad molecular weight distribution
Polypropylene having a melt flow rate MFR.sub.2 (230.degree. C.) of at least 20 g/10 min; and a M.sub.w/M.sub.n ratio of at least 15.0.
US-9,587,043 Polymer composition and a power cable comprising the polymer composition
A crosslinkable and crosslinked polymer composition with improved DC electrical properties and a cable surrounded by at least one layer comprising the polymer...
US-9,587,042 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and...
An object of the present invention is to provide a process for producing a modified conjugated diene-based polymer suitable for preparing a polymer composition...
US-9,587,041 Organometallic compound in solid form, process for preparing the same and use thereof
The present invention provides a solid organomagnesium precursor having formula {Mg(OR')X}.a{MgX.sub.2}.b{Mg(OR').sub.2}.c{R'OH}, wherein R' is selected from a...
US-9,587,040 Magnesium dichloride-alcohol adducts and catalyst components obtained therefrom
Process for the preparation of solid particles of a magnesium-chloride alcohol adduct comprising (a) forming an emulsion between a MgCl.sub.2 .alcohol adduct in...
US-9,587,039 Fluorinated-containing macroinitiator and production process for the same
Provided is a fluorine-containing macroinitiator, particularly a fluorine-containing macroinitiator that enables production of a fluorine-containing block...
US-9,587,038 Manufacturing of microcellulose
The present invention relates to a process for producing microcellulose comprising a) acidifying fibrous cellulosic material, b) washing the acidified...
US-9,587,037 Process for recovering an esterified cellulose ether from a reaction product mixture
A process for recovering an esterified cellulose ether from a reaction product mixture obtained from a reaction of (a) a cellulose ether with (b) an aliphatic...
US-9,587,036 Cross-species-specific PSMAxCD3 bispecific single chain antibody
The present invention relates to a bispecific single chain antibody molecule comprising a first binding domain capable of binding to an epitope of human and...
US-9,587,035 Assay for benzylpiperazine and metabolites
The invention relates to the detection and quantification of 1-benzylpiperazine and its metabolites. The invention is underpinned by novel polyclonal antibodies...
US-9,587,034 Anti-mIgE antibodies that bind to the junction between CH4 and C.epsilon.mX domains
Antibodies binding to junction regions between the CH4 and C.epsilon.mX domains of membrane-bound IgE and uses thereof in treating IgE-mediated diseases such as...
US-9,587,033 Therapeutic and diagnostic applications targeting TNK-1
Disclosed herein are novel antibodies specific to Tnk1 or variants thereof. Also disclosed are methods of using such antibodies. The methods include therapeutic...
US-9,587,032 IgE antibodies for the inhibition of tumor metastasis
The present invention provides novel IgE antibodies useful for inhibiting or preventing metastatic cancer. Also provided are methods to inhibit tumor metastasis...
US-9,587,031 DNA encoding an anti-CD40 IgG2 antibody having amino acid mutations
The present invention can provide a monoclonal antibody which comprises a heavy chain constant region which is IgG2 wherein valine at position 234, glutamine at...
US-9,587,030 Anti-hOX40L antibodies, uses, and methods
The present invention relates to anti-human OX40L antibodies, new medical uses and methods.
US-9,587,029 Human antibodies to the glucagon receptor and methods of use thereof
The present invention provides antibodies that bind to the human glucagon receptor, designated GCGR and methods of using same. According to certain embodiments...
US-9,587,028 Affinity matured anti-CCR4 humanized monoclonal antibodies and methods of use
The present invention provides affinity matured humanized monoclonal antibodies, bi-specific antibodies, antibody conjugates, and fusion proteins that bind to...
US-9,587,027 Methods for binding members of interleukin-4 receptor .alpha. (IL-4R.alpha.)
Binding members, especially antibody molecules, for interleukin (IL)-4 receptor alpha (IL-4R.alpha.), and their therapeutic use e.g. in treating or preventing...
US-9,587,026 Anti-interleukin-4 receptor antibodies
Methods for treating medical conditions induced by interleukin-4 involve administering an IL-4 antagonist to a patient afflicted with such a condition. Suitable...
US-9,587,025 Non-sialylated anti-inflammatory polypeptides
This invention concerns anti-inflammatory agents, compositions, and methods for treating inflammatory disorders.
US-9,587,024 Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor 1 (IGF-1)
The present invention provides an antibody or antigen-binding fragment thereof that binds .alpha..sub.v.beta..sub.3 integrin, as well as methods of use in the...
US-9,587,023 Recombinant monovalent antibodies
The invention relates to recombinant monovalent antibodies which are heterodimers of a first protein chain comprising the variable domain of the heavy chain of...
US-9,587,022 Glycan-modified anti-CD4 antibody with improved HIV-1 neutralizing activity
Disclosed herein are glycan-modified anti-CD4 monoclonal antibodies with N-linked glycans attached to the variable region. Expression vectors and cell lines...
US-9,587,021 CD3-binding molecules capable of binding to human and non-human CD3
CD3-binding molecules capable of binding to human and non-human CD3, and in particular to such molecules that are cross-reactive with CD3 of a non-human mammal...
US-9,587,020 Chimeric antigen receptor and methods of use thereof
The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence...
US-9,587,019 CD33 antibodies and use of same to treat cancer
The invention provides murine, chimeric, and humanized antibodies that specifically bind to CD33. The antibodies are useful for treatment and diagnoses of...
US-9,587,018 Polynucleotides encoding human oncostatin M antibodies
Antibodies and compositions capable of neutralizing oncostatin M biological functions are useful in treating diseases and disorders associated with oncostatin...
US-9,587,016 Treatment method for lung remodeling diseases
The present invention relates to methods and medicaments useful for pre-treatment, treatment, or amelioration of lung remodeling disease. Methods and...
US-9,587,015 Anti-human CTGF antibody
Novel anti-human CTGF antibodies having excellent binding activity and/or neutralizing activity, as compared with conventional anti-human CTGF antibodies, are...
US-9,587,014 TDP-43 specific binding molecules
Provided are novel TAR DNA-binding proteins of 43 kDa ("TDP-43")-specific binding molecules including polypeptides such as human antibodies, as well as...
US-9,587,013 Immunoaffinity isolation of modified peptides from complex mixtures
The invention provides methods for isolating a modified peptide from a complex mixture of peptides, the method comprising the steps of: (a) obtaining a...
US-9,587,012 Bispecific HIV-1 neutralizing antibodies
In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV.
US-9,587,011 Monoclonal antibodies capable of reacting with a plurality of influenza virus A subtypes
Monoclonal antibodies directed against the influenza A virus are described, which have the advantageous and unpredicted property of being able to bind a...
US-9,587,010 Neutralizing anti-influenza A virus antibodies and uses thereof
The invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to an epitope in the stem region of an influenza A...
US-9,587,009 Media for affinity chromatography
The invention relates generally to solid supports for chromatography. In specific embodiments the invention provides for solid supports suitable for affinity...
US-9,587,008 Method of producing recombinant vitamin K dependent proteins
Methods for producing cell lines with high levels of biologically active recombinant vitamin K dependent proteins are described. The transfected cell lines do...
US-9,587,007 CTLA4 proteins and their uses
The present disclosure relates to CTLA4 proteins and uses of such proteins, for example to treat diseases associated with the dysregulation of immune responses.
US-9,587,006 IGF-I poly (ethylene glycol) conjugates
Herein is reported a method for producing of a polypeptide conjugated to one poly (ethylene glycol) comprising a) providing a nucleic acid encoding an...
US-9,587,005 Glucagon analogs exhibiting GIP receptor activity
Provided herein are glucagon analogs which exhibit potent activity at the GIP receptor, and, as such are contemplated for use in treating diabetes and obesity....
US-9,587,004 Natriuretic polypeptides
This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal...
US-9,587,003 Modified polynucleotides for the production of oncology-related proteins and peptides
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related...
US-9,587,002 Sequence of nucleotides and peptides GSE 24.2 of dyskerin, which can induce telomerase activity, method for...
This invention relates to a compound that induces or activates telomerase activity based on the nucleotide sequence of the GSE 24.2 fragment of dyskerin or the...
US-9,587,001 Conjugated knottin mini-proteins containing non-natural amino acids
Disclosed are knottin peptides containing non-natural amino acids so that they can be formed by chemical conjugation into two or more knottin monomers. The...
US-9,587,000 VP16-CREB fusion gene
The present application describes a cell that has integrated into its genome fusion molecule V16-CREB.
US-9,586,999 Methods and compositions related to improving properties of pharmacological agents targeting nervous system
Disclosed are compositions and methods related to improving pharmacological properties of bioactive compounds targeting nervous system.
US-9,586,998 Methods of propagating monkey adenoviral vectors
The invention provides methods for propagating a monkey adenovirus in a cell, including a human cell, comprising one or more gene products isolated from a human...
US-9,586,997 Antigen-specific T cell receptors and T cell epitopes
The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T...
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