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Patent # Description
US-9,593,177 Polyethylene
The present invention relates to a low density polyethylene having a molecular weight distribution Mw/Mn which is greater than 15, a storage modulus G' (5 kPa)...
US-9,593,176 Solid titanium catalyst component, olefin polymerization catalyst, and process for producing olefin polymer
The present invention provides a process for producing an .alpha.-olefin polymer comprising polymerizing or copolymerizing (a) C.sub.3 or higher .alpha.-olefin...
US-9,593,175 Solid titanium catalyst component for ethylene polymerization, ethylene polymerization catalyst and ethylene...
Provided are a solid titanium catalyst component for ethylene polymerization which can polymerize ethylene at a high activity and which can provide an ethylene...
US-9,593,174 Acetoacetyl group-containing polyvinyl alcohol resin powder composition, and production method therefor
Acetoacetyl group-containing polyvinyl alcohol resin powder composition containing a C1 to C3 alcohol in an amount of 0.5 to 4 wt % is produced by allowing a...
US-9,593,173 Low temperature cure polymerization initiator
A polymerization initiator system for reactive monomers and unsaturated polymers which is contains a Group 4 transition metal or Group 4 transition...
US-9,593,172 Ziegler-natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the...
A catalyst composition for use as precursor for Ziegler-Natta catalyst system, said catalyst composition comprising a combination of magnesium moiety, titanium...
US-9,593,171 Catalyst components for the polymerization of olefins
A porous solid catalyst component comprising a magnesium halide, a titanium compound having at least a Ti-halogen bond and at least two electron donor compounds...
US-9,593,170 Compound, photocurable composition, and methods for producing patterned film, optical component, circuit board,...
A compound that increases the photocuring rate of a photocurable composition and reduces the force for releasing a cured product from a mold is provided. A...
US-9,593,169 Omega-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical...
Polymeric compounds having spatially controlled bioconjugation sites are described. Functionalization is achieved by selective .omega.-terminal chain extension...
US-9,593,168 Process for degrading nitrile rubbers in the presence of catalysts having an increased activity
A process of degrading nitrile rubbers comprises subjecting them to a metathesis reaction in the presence of specific catalysts with increased activity.
US-9,593,167 Antibodies and immunoconjugates and uses therefor
Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
US-9,593,166 Monoclonal antibodies against antithrombin .beta.
This patent document relates to antibodies, antigen-binding antibody fragments (Fabs), and other protein scaffolds, directed against human antithrombin .beta....
US-9,593,165 Antibody capable of specifically recognizing transferrin receptor
The present invention provides an antibody, in which the heavy chain first complementarity determining region (VH CDR1), the heavy chain second complementarity...
US-9,593,164 Bispecific EGFR/c-Met antibodies
Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
US-9,593,163 Oncostatin M receptor antigen binding proteins
The invention provides anti-oncostatin M receptor-.beta. (OSMR) antigen binding proteins, e.g., antibodies and functional fragments, derivatives, muteins, and...
US-9,593,162 Internalizing human monoclonal antibodies targeting prostate cancer cells in situ
This invention provides a method that allows selection of antibodies against cells (e.g., tumor cells) in situ using laser capture microdissection. By...
US-9,593,161 Humanization of rabbit antibodies using a universal antibody framework
The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a...
US-9,593,160 Engineered microbe-targeting molecules and uses thereof
Described herein are engineered microbe-targeting or microbe-binding molecules, kits comprising the same and uses thereof. Some particular embodiments of the...
US-9,593,159 Human binding molecules capable of neutralizing influenza A viruses of phylogenetic group 1 and phylogenetic...
Described are binding molecules, such as human monoclonal antibodies, that bind to an epitope in the stem region of hemagglutinin of influenza A viruses of...
US-9,593,158 Process for the preparation of gelatin
The present invention relates to a process for preparing gelatin comprising a step of incubating a material comprising collagen with an enzyme composition...
US-9,593,157 Chimeric polypeptides comprising G protein-coupled receptors and VHH antibodies
Described are polypeptides and their use for screening and drug discovery. More specifically, the disclosure provides chimeric polypeptides comprising a...
US-9,593,156 Insulin analog dimers
Disclosed herein are insulin analog dimers having unique insulin receptor agonist activity based on insulin polypeptide sequences, the site of dimerization and...
US-9,593,155 Oxyntomodulin analogs
Peptide analogs of oxyntomodulin (OXM, glucagon-37), which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV)...
US-9,593,154 Engineered polypeptides having enhanced duration of action
Compounds are provided having inter alia good duration of action, high potency and/or convenient dosing regimens including oral administration. The compounds...
US-9,593,153 Modified apelin polypeptides
The present invention relates to polypeptides and their uses as apelin inhibitors. More particularly, the present invention relates to a polypeptide comprising...
US-9,593,152 Methods of treating disease with fusion molecules comprising IL-15 variants
The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making such...
US-9,593,151 Use of fusion protein
Disclosed is the use of a fusion protein in drugs for stimulating differentiation of bone marrow mesenchymal stem cells to hematopoietic stem/progenitor cells,...
US-9,593,150 Immunoglobulin-binding human mycoplasma antigens and methods of use thereof
Provided herein methods of alleviating the symptoms of multiple myeloma in a patient or subject in need thereof, methods of treating multiple myeloma in a...
US-9,593,149 Amylin and calcitonin receptor agonist
The present invention relates to peptides comprising an amino acid sequence SEQ ID NO: 1 (EASELSTAALGRLSAELHELATLPRTETGPESP), analogs and derivatives thereof...
US-9,593,148 DPP8 and DPP9 peptide inhibitors
The present invention relates to non-competitive allosteric peptide inhibitors of DPP9 and/or DPP8, competitive peptides binding to SUMO1, nucleic acid...
US-9,593,147 IgA-binding peptide and purification of IgA using the same
This invention relates to: a peptide which comprises an amino acid sequence consisting of 12 to 18 amino acid residues represented by ...
US-9,593,146 CD44v6-derived peptides for treating metastasizing cancer
The present invention relates to compounds, pharmaceutical compositions and methods for treating different forms of pancreatic cancer.
US-9,593,145 Secondary structure stabilized NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of...
US-9,593,144 FPR1 antagonist derivatives and use thereof
A dipeptide derivative as formyl peptide receptor 1 (FPR1) antagonist is provided. The dipeptide derivative is represented by formula (I), ##STR00001## ...
US-9,593,143 Method for purifying protein complexes
The present invention provides a method for the purification of complexes comprising a stress protein complexed to a peptide or peptide fragment, from a source...
US-9,593,142 Aldehyde capture ligation technology for synthesis of amide bonds
The present invention relates to ligation agents and their use in making an amide ligation product. Methods of making the ligation agents are also disclosed.
US-9,593,141 Lin28/let-7 crystal structures, purification protocols, and molecular probes suitable for screening assays and...
The invention provides compositions and methods for regulating microRNA (miRNA) biogenesis. The invention also relates to compositions and methods for treating...
US-9,593,140 Antibacterial tylosin derivatives and methods for their preparation
The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (I); a pharmaceutical or veterinary composition...
US-9,593,139 Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting...
Compositions, kits, and methods for treatment of cancers are generally provided. In some embodiments, the compositions, kits, and methods comprise a platinum...
US-9,593,138 Nitrile-containing enzyme inhibitors and ruthenium complexes thereof
The invention provides nitrile-containing protease inhibitors caged to ruthenium compounds. The nitrile-caged ruthenium compounds provide inactivated inhibitors...
US-9,593,137 Guanine analogs as telomerase substrates and telomere length affectors
This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are...
US-9,593,136 Compounds for inhibiting 1-deoxy-D-xylulose-5-phosphate reductoisomerase
In particular, the compound is effective to inhibit Dxr in Mycobacterium tuberculosis (Mtb). The present invention relates to compounds having general formula...
US-9,593,135 Compositions comprising alkoxysilane-containing isocyanates and acid stabilisers
The present invention relates to a composition comprising (A) an isocyanate of formula (I) OCN-A-SiR.sup.1R.sup.2R.sup.3 (I), wherein A is straight-chain,...
US-9,593,134 Complexes useful as active components in supported epoxidation catalysts
Method of preparing epoxidation catalysts are disclosed, including methods comprising reacting an inorganic siliceous solid with a metal complex of the...
US-9,593,133 Organosilane precursors for ALD/CVD silicon-containing film applications
Disclosed are Si-containing thin film forming precursors, methods of synthesizing the same, and methods of using the same to deposit silicon-containing films...
US-9,593,132 Metal-organic frameworks (MOF) for gas capture
The present invention relates to a metal organic framework comprising of a metal ion (M) and an organic ligand wherein more than one hydroxy ligand are present...
US-9,593,131 Copper-cysteamine and methods of use
Structure and luminescence properties of a new Cu-Cyteamine (Cu-Cy) crystal material are provided. The crystal structure of the Cu-Cy is determined by single...
US-9,593,130 Polymorphous forms III and IV of N-benzoyl-staurosporine
The present invention relates to a crystalline form III and a crystalline form IV of N-benzoyl staurosporine.
US-9,593,129 Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer
The present invention provides MDM2 inhibitor compounds of Formula I, ##STR00001## wherein the variables are defined above, which compounds are useful as...
US-9,593,128 Tetrazole-substituted arylamides as P2X.sub.3 and P2X.sub.2/3 antagonists
Compounds of the formula V: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein, R.sup.2 is optionally substituted phenyl, optionally...
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