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Patent # Description
US-9,598,711 Pichia ciferrii cells and uses thereof
The invention relates to genetically modified Pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.
US-9,598,710 Genetically modified organism for the production of lipids
The invention provides an isolated genetically modified non-mammalian organism, wherein the activity of acyl-CoA:sterol acyltransferase/sterol O-acyltransferase...
US-9,598,709 Genetically engineered and stress resistant yeast cell with enhanced MSN2 activity and method of producing...
Provided is a yeast cell having a stress tolerance, wherein the yeast cell has enhanced MSN2 activity, a method of producing the yeast cell, and a method of...
US-9,598,708 Processes for starting up and operating deep tank anaerobic fermentation reactors for making oxygenated organic...
Processes for starting up and operating anaerobic, deep tank fermentation systems to anaerobically bioconvert hydrogen and carbon monoxide in a gaseous...
US-9,598,707 Method to increase the yield of products in plant material
A method to increase the production of products of interest in plant material including plant cultures, such as, for example, cell suspension cultures, root...
US-9,598,706 Production of fatty acids and derivatives thereof
Compositions and methods for production of fatty alcohols using recombinant microorganisms are provided as well as fatty alcohol compositions produced by such...
US-9,598,705 Thermococcus onnurineus MC02 and method of hydrogen production using thereof
The present invention provides Thermococcus onnurineus MC02 strain (accession no. KCTC12511BP) having increased hydrogen production ability, wherein the...
US-9,598,704 Inkjet gene printing
Provided herein are methods and apparatuses for transfecting a cell with a compound of interest by stressing the cell, e.g. with shear stress. The compound of...
US-9,598,703 Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
An isolated linear nucleic acid molecule comprising in this order: a first adeno-associated virus (AAV) inverted terminal repeat (ITR), a nucleotide sequence of...
US-9,598,701 Down-regulation of gene expression using artificial MicroRNAs for silencing fatty acid biosynthetic genes
Isolated nucleic acid fragments comprising precursor miRNAs, and artificial miRNAs and their use in down-regulating gene expression of fatty acid biosynthetic...
US-9,598,700 Methods and compositions for processing biomass with elevated levels of starch
Genetically engineered plants having altered levels of one or more starch regulation enzymes and a polysaccharide degrading enzyme are provided. Methods of...
US-9,598,699 Protein having glycoalkaloid biosynthetic enzyme activity and gene encoding the same
An object of the present invention is to provide DNA of a glycoalkaloid biosynthetic enzyme of a solanaceous plant (Solanaceae) such as a potato. The present...
US-9,598,698 Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof
The present invention relates to methods for co-silencing expression of genes in a filamentous fungal strain by transitive RNA interference. The present...
US-9,598,697 Recombinant bacterium to decrease tumor growth
A recombinant bacterium capable of reducing tumor growth is provided, wherein said recombinant bacterium is capable of: a. increased expression of a nucleic...
US-9,598,696 Bacteria and method for synthesizing fatty acids
The present invention discloses a process for increasing the production of free fatty acids at high yield (close to maximum theoretical yield), with various...
US-9,598,695 Modulation of T cell signaling threshold and T cell sensitivity to antigens
MicroRNAs (miRNAs) are a diverse and abundant class of .about.22-nucleotide (nt) endogenous regulatory RNAs that play a variety of roles in animal cells by...
US-9,598,694 Micro-RNAs involved in macular degeneration
The present invention relates to the involvement of miR function in the development of age-related macular degeneration (AMD). It is shown that miR-23, miR-24...
US-9,598,693 Oligomeric compounds and compositions for the use in modulation of micrornas
Compounds, compositions and methods are provided for modulating the levels expression, processing and function of miRNAs. The compositions comprise oligomeric...
US-9,598,692 Multivalent phage display systems and methods
The present invention relates to vectors, methods and systems for polypeptide display and selection. Specifically, the present invention relates to vectors,...
US-9,598,691 Irreversible electroporation to create tissue scaffolds
The present invention provides engineered tissue scaffolds, engineered tissues, and methods of using them. The scaffolds and tissues are derived from natural...
US-9,598,690 Method for forming nanoparticles having predetermined shapes
Articles and methods for forming nanostructures having unique and/or predetermined shapes are provided. The methods and articles may involve the use of nucleic...
US-9,598,689 Genetically modified strain of S. cerevisiae engineered to ferment xylose and arabinose
The present invention provides a microorganism capable of fermenting arabinose to a desired product such as ethanol. In some embodiments, the organism is also...
US-9,598,688 Process for generation of protein and uses therof
A method of generating a protein with an improved functional property, the method comprising: (a) identifying at least one Target amino acid Residue in a...
US-9,598,687 Methods for processing coagulation factors
The present application relates to methods for purifying recombinant coagulation factor proteins, including for example, prothrombin (Factor II). In...
US-9,598,686 Use of Galerina marginata genes and proteins for peptide production
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in...
US-9,598,685 Engineered botulinum neurotoxin
Disclosed herein are botulinum neurotoxin (BoNT) polypeptides with a modified receptor binding domain of Clostridial botulinum serotype B (B-H.sub.c),...
US-9,598,684 Rothia species gluten-degrading enzymes and uses thereof
There are gluten-degrading enzymes found in Rothia species bacteria that are capable of breaking peptide bonds in -XPQ-, -QQP-, -PPF-, -LYP- and/or...
US-9,598,683 Non-diffusive botulinum toxin causing local muscle paralysis, and purification method thereof
A method for purifying a non-spreading botulinum toxin that causes local muscle paralysis and a non-spreading botulinum toxin obtained thereby includes the...
US-9,598,682 Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose
Described herein are methods and genetically engineered cells useful for uncapping a mannose-6-phosphate residue on an oligosaccharide.
US-9,598,681 Thermostable .beta.-xylosidase belonging to GH family 3
A thermostable .beta.-xylosidase, having a .beta.-xylosidase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by SEQ...
US-9,598,680 G16 glucoamylase compositions and methods
The invention is directed to novel glucoamylases.
US-9,598,679 Polymerase compositions and uses
A composition having nucleic acid polymerase activity, which comprises an active nucleic acid polymerase and an excess amount of a non-functional mutant nucleic...
US-9,598,678 Microbial strains and methods of making and using
Microbial strains are provided, as are methods of making and using such microbial strains.
US-9,598,677 Use of human biliverdin reductase and fragments thereof for the treatment of protein kinase C-delta and ERK...
The present invention is directed to methods of modulating PKC-.delta. activity and PKC-.delta./ERK complex activity in cells via biliverdin reductase. Methods...
US-9,598,676 Composition useful as rotavirus vaccine and a method therefor
Compositions and methods related to live or live attenuated pre-conditioned and typical viruses such as rotaviruses are disclosed. The live attenuated...
US-9,598,675 Method for preparing mesenchymal stem cell-like cells and cardiomyocyte-like cells
The present invention provides a method for preparing mesenchymal stem cell-like cells and cardiomyocyte-like cells from induced pluripotent stem cells. With...
US-9,598,674 Dendritic cells obtained from induced pluripotent stem cells (iPSCs)
The invention relates to dendritic cells produced from human induced pluripotent stems cells (iPSC). The invention also relates to methods for making and...
US-9,598,673 Treatment of disc degenerative disease
Methods and compositions for treating or ameliorating lower back pain by administering an effective amount of one or more cell types, alone, and/or in...
US-9,598,672 Production of extracellular matrix, conditioned media and uses thereof
Provided is a matrix for promoting survival and differentiation of cells transplanted thereon, comprising a base matrix and a cell-made matrix thereon. Methods...
US-9,598,671 Cyprinid herpesvirus II-sensitive brain tissue cell line of Carassius auratus gibelio and establishing method...
The present invention discloses a cyprinid herpesvirus II-sensitive brain tissue cell line of Carassius auratus gibelio and establishing method and use thereof....
US-9,598,670 Methods for culture and production of single cell populations of human embryonic stem cells (HESCS)
We used ACCUTASE.RTM., a commercially available cell detachment solution, for single cell propagation of pluripotent hESCs. Unlike trypsin dissociation,...
US-9,598,669 Composition for collecting placental stem cells and methods of using the composition
The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem...
US-9,598,668 Temperature-responsive cell culture substrate and method for producing the same
A substrate having a pattern of two or more materials exhibiting different grafting efficiencies for a temperature-responsive polymer that varies its...
US-9,598,667 Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
Protein glycosylation greatly influences the structure, function, and pharmacokinetics of recombinant proteins. Here, growth media supplemented with metal ions...
US-9,598,666 Fluid distribution in a sample exposure device
The invention relates to fluid distribution in an exposure device. The exposure device, in some examples, is a device for exposing living cell cultures or...
US-9,598,665 Racking arm tank outlet port
The racking arm includes a housing affixable to a tank side wall. A racking shaft extends through the housing with an inlet pipe coupled to an inside end of the...
US-9,598,664 Composition for cleaning a heat transfer system having an aluminum component
Disclosed herein is a cleaner concentrate comprising: greater than 10 weight percent of a freezing point depressant, 0.5 to 35 weight percent of oxalic acid,...
US-9,598,663 Liquid detergent composition for clothing
Provided is a liquid detergent composition for clothing which is formed by blending (a) a nonionic surfactant represented by Formula (1), (b) an anionic...
US-9,598,662 Fermented pineapple-based fruit solutions for cleaning compositions
Described herein are natural cleaning compositions comprising fermented fruit solutions, methods for making the same, and methods for using the same. The...
US-9,598,661 Cleaning compositions including fermented fruit solutions, builder, and surfactant
Described herein are cleaning compositions comprising fermented fruit solutions and builders, methods for making the same, and methods for using the same. The...
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