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Patent # Description
US-9,598,510 Telechelic polyolefin and preparation thereof
Telechelic polyolefin of formula(I) and its derivatives: CH.sub.2.dbd.CH--(CH.sub.2).sub.p-A-Z (I) wherein: A represents a (co)polymer comprising at least 95...
US-9,598,509 Magnesium dichloride-ethanol adducts and catalyst components obtained therefrom
A solid adduct comprising magnesium chloride and ethanol in which the moles of ethanol per mole of magnesium chloride range from 2 to 5 and in which the ratio...
US-9,598,508 Modified conjugated diene polymer, modified rubber composition comprising same, and method for producing...
Disclosed are a method of preparing a modified conjugated diene-based polymer, a modified conjugated diene-based polymer prepared thereby, and a rubber...
US-9,598,507 Modified liquid diene-based rubber and production process for the same
A modified liquid diene-based rubber (A) including, in a molecule, a modified group (a) containing a (meth)acryloyl group as a part thereof and at least one...
US-9,598,506 Catalyst compositions and their use for hydrogenation of nitrile rubber
This invention relates to novel catalyst compositions based on Ruthenium- or Osmium-based complex catalysts and to a process for selectively hydrogenating...
US-9,598,505 Silyl-derivatives of polysaccharides
The present invention relates to novel silyl-derivatives of polysaccharides and their salts, the processes for their preparation and their use in...
US-9,598,504 Process for the removal of endotoxins to produce medical quality chitosan and other polysaccharides
A process of making low-endotoxin chitosan or alkali-stable polysaccharide is performed by suspending bulk chitosan fibers or flakes or alkali-stable...
US-9,598,503 Methods and systems for polymer precipitation and generation of particles
Processes for precipitating a polymer from a polymer-containing fluid are disclosed, which include providing a vessel housing a medium that provides one or more...
US-9,598,502 Method of manufacturing ultra-low viscosity hydroxyalkyl cellulose through partial neutralization method
The present invention relates to a method of manufacturing ultra-low viscosity hydroxyalkyl cellulose through a partial neutralization method, and the method...
US-9,598,501 Antibody-immobilized carrier, method of producing antibody-immobilized carrier, and use of said...
The present invention provides an antibody-immobilized carrier that can be used in antibody screening, a method of producing the antibody-immobilized carrier,...
US-9,598,500 Binding molecules for BCMA and CD3
The present invention relates to a binding molecule comprising a first and a second binding domain, wherein the first binding domain is capable of binding to...
US-9,598,499 Antigen binding formats for use in therapeutic treatments or diagnostic assays
The present invention relates to antigen binding formats for use in therapeutic treatments or diagnostic assays. The present invention relates to an...
US-9,598,498 Anti-ErbB3 antibodies
Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used...
US-9,598,497 RSPO3 binding agents and uses thereof
The present invention relates to RSPO-binding agents, particularly RSPO3-binding agents and methods of using the agents for treating diseases such as cancer....
US-9,598,496 Antibody capable of specifically recognizing transferrin receptor
An object of present invention is to provide a complete human anti-human TfR antibody, which specifically recognizes human TfR, inhibits the survival or growth...
US-9,598,495 Use of semaphorin-4D binding molecules for treating neurodegenerative disorders
Provided herein are methods for alleviating symptoms in a subject having a neurodegenerative disorder, comprising administering to the subject an effective...
US-9,598,494 Anti-CD40 antibody mutants
A mutant of a potentially therapeutic anti-CD40 antibody is provided which mutant has reduced ADCC and CDC activities designed to be optimized as a...
US-9,598,493 Human monoclonal antibodies against CD25
Isolated human monoclonal antibodies which bind to and inhibit human CD25, and related antibody-based compositions and molecules, are disclosed. The human...
US-9,598,492 Human monoclonal antibodies specific for CD22
Disclosed herein are isolated human monoclonal antibodies that specifically bind human CD22 with a dissociation constant (K.sub.d) of 25 nM or less. Nucleic...
US-9,598,491 Methods for the treatment of infections and tumors
PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or...
US-9,598,490 Folate receptor 1 antibodies and immunoconjugates and uses thereof
Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using...
US-9,598,489 Human alpha-folate receptor chimeric antigen receptor
The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell...
US-9,598,488 Blockage of interferon-gamma for prevention of polymicrobial synergy
The present invention is directed to methods for treating a viral respiratory infection in a subject, preventing polymicrobial synergy in a subject, or...
US-9,598,487 Stable and soluble antibodies
The invention provides antibodies that are modified to reduce aggregration propensity, and methods of producing such antibodies. The present invention also...
US-9,598,486 Methods for treating osteogenesis imperfecta
The present invention provides methods for treating and improving the symptoms of osteogenesis imperfecta (OI) in a subject by administering to the subject a...
US-9,598,485 Anti-tau antibodies and methods of use
The present invention relates to anti-Tau antibodies, such as antibodies that bind to a phosphorylated epitope on human Tau protein with high specificity and/or...
US-9,598,484 Human anti-tau antibodies
Provided are human tau-specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid...
US-9,598,483 Monoclonal antibody binding specifically to DLL4 and use thereof
The present invention relates to a novel monoclonal antibody that binds specifically to delta-like ligand (DLL4), and more particularly to a monoclonal antibody...
US-9,598,482 Monoclonal antibodies capable of reacting with a plurality of influenza virus A subtypes
Monoclonal antibodies directed against the influenza A virus are described, which have the advantageous and unpredicted property of being able to bind a...
US-9,598,481 Anti-hemagglutinin antibodies and methods of use
The present invention provides anti-hemagglutinin antibodies, compositions comprising anti-hemagglutinin antibodies, and methods of using the same.
US-9,598,480 Recombinant NEL-like (NELL) protein production
The present invention provides a method and system for producing a NELL protein. The method and system comprise a CELL encoding a NELL protein or peptide and a...
US-9,598,479 Nanoparticle-peptide compositions
The present invention provides nanoparticles and compositions comprising such nanoparticles, as well as methods for intracellular delivery of peptides, and...
US-9,598,478 Peptides for the treatment of neurodegenerative diseases
An isolated peptide comprising a Huntingtin (Htt) amino acid sequence being no longer than 15 amino acids, wherein said Htt amino acid sequence comprises the...
US-9,598,477 Methods of treating metabolic disorders
The present invention addresses the problem of providing a means which is effective for the induction of the differentiation of a brown adipocyte and therefore...
US-9,598,476 Nucleic acid molecules encoding muteins of human tear lipocalin which bind PCSK9
The present disclosure relates to novel lipocalin muteins which bind to PCSK9. The disclosure also provides corresponding nucleic acid molecules encoding...
US-9,598,475 Methods of preventing or treating brain diseases
The present invention relates to methods for preventing or treating neurological diseases, particularly brain diseases, and improving cognitive functions using...
US-9,598,474 Nutritive fragments, proteins and methods
Nutritive proteins are provided. In some embodiments the nutritive proteins comprise a first polypeptide sequence comprising a fragment of a naturally-occurring...
US-9,598,473 Trichome-specific transcription factor modulating terpene biosynthesis
The present invention relates to identification and isolation of zinc finger transcription factor in tomato that specifically expresses in glandular trichomes...
US-9,598,472 Isolated polypeptide of the toxin A and toxin B proteins of C. difficile and uses thereof
This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C. difficile toxin A and toxin B as set...
US-9,598,471 Bacteriocin with novel activity
A bacteriocin produced constitutively by Streptococcus thermophilus strain 110 (NRRL B59671), thermophilin 110, kills and/or inhibits the growth Streptococcus...
US-9,598,470 Compositions and methods to prevent cancer by stabilizing P53 through non MDM2-mediated pathways
The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural...
US-9,598,469 HIV-1 south african subtype C env proteins
The present invention relates to polynucleotides encoding immunogenic HIV polypeptides. Uses of the polypeptides in applications including immunization,...
US-9,598,468 Polypeptides and vectors for targeting HER2/neu expressing cells and uses thereof
Various aspects of the invention provide for capsids, parvovirus capsids, hybrid parvovirus capsids, parvovirus vectors, hybrid parvovirus vectors, hybrid...
US-9,598,467 Recombinant HCV E2 glycoprotein
The invention provides modified hepatitis C virus (HCV) E2 glycoproteins comprising the HCV-E2 receptor-binding domain (RBD) including the HVR1, HVR2 and igVR...
US-9,598,466 Glycopeptide constructs and uses thereof
Glycopeptide conjugates, and methods of making and using such conjugates are disclosed. Certain glycopeptide conjugates comprise tumor associated carbohydrate...
US-9,598,465 Cell penetrating peptides for intracellular delivery of molecules
A cell-penetrating peptide characterized in that it comprises an amino acid sequence: ...
US-9,598,464 Biologically active peptides
The invention provides a method of making a peptide or peptide derivative comprising the amino acid sequence comprising imfwydcye or a variant amino acid...
US-9,598,463 Mucin hypersecretion inhibitors and methods of use
Peptides are provided that comprise less than 24 amino acids. The peptides have an amino acid sequence selected from the group consisting of: (a) an amino acid...
US-9,598,462 Composite antigenic sequences and vaccines
The invention relates to composite antigens comprising a peptide with contiguous amino acid sequence derived from a plurality of antigenic epitopes of one or...
US-9,598,461 Method of purifying therapeutic proteins
The present invention relates generally to a method of reducing the level of at least one protein selected from the group consisting of plasminogen, tissue...
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