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Patent # Description
US-9,603,949 Oligonucleotide-based probes for detection of bacterial nucleases
The present invention relates to a rapid detection of microbial-associated nuclease activity with chemically modified nuclease (e.g., ribonuclease) substrates,...
US-9,603,948 Methods and compositions for treating multiple sclerosis and related disorders
This disclosure provides therapeutic compositions and methods for treating multiple sclerosis or a multiple sclerosis-related disorder in a subject in need...
US-9,603,946 Peptide sequence design and use thereof for peptide-mediated siRNA delivery
Peptides that have been found to facilitate the delivery of siRNA molecules into cells and to function in siRNA mediated silencing of cellular targets are...
US-9,603,945 Heparosan polymers and methods of making and using same for the enhancement of therapeutics
Compositions, methods, and systems are disclosed for the development and use of heparosan, a natural polymer related to heparin, as a new therapeutic modifying...
US-9,603,944 Carrier-free biologically-active protein nanostructures
The present disclosure provides compositions and methods for efficient and effective protein delivery in vitro and in vivo. In some aspects, proteins are...
US-9,603,943 Polyesteramide platform for site specific drug delivery
A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein....
US-9,603,942 Somatostatin-dopamine chimeric analogs
The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of...
US-9,603,941 Method of preparing dendritic drugs
Synthetic design of drug-incorporated novel dendrimer structures for quantitatively controlled drug delivery. The dendritic drugs have better control and thus a...
US-9,603,940 Metal salen complex derivative and process for production thereof
A metal-salen complex derivative with an excellent yield and stability is provided and a method for producing such a metal-salen complex derivative is provided....
US-9,603,939 Platform drug delivery system utilizing crystal engineering and theanine dissolution
A method of treating Hodgkin's disease in a subject. The method involves administering to the subject an effective amount of a water-soluble composition which...
US-9,603,938 Platform drug delivery system utilizing crystal engineering and theanine dissolution
A method of making a water-soluble doxorubicin-theanine cocrystal composition. The method includes the steps of providing a quantity of doxorubicin, adding a...
US-9,603,937 Platform drug delivery system utilizing crystal engineering and theanine dissolution
A platform drug delivery system and a method of improving the delivery of low solubility pharmaceuticals utilizing crystal engineering and Theanine dissolution...
US-9,603,936 Polyethylene glycol based prodrug of adrenomedullin and use thereof
The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment...
US-9,603,935 Oral dispersible films
Described herein are orodispersible films comprising a film forming hydrophobic polymer, a disintegrant, a plasticizer and a stabilizer.
US-9,603,934 Anhydrous hydrogel composition and delivery system
The present disclosure relates to anhydrous hydrogels useful as mucoadhesive (oral compositions) or as topical agents and may be used to deliver an active agent...
US-9,603,933 Composition for enteric hard capsules, and enteric hard capsule prepared using the composition
A composition for enteric hard capsules, and an enteric hard capsule prepared using the composition. The composition for enteric hard capsules may include...
US-9,603,932 Intravaginal ring comprising polyurethane composition for drug delivery
Intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the...
US-9,603,931 Macromolecule for delivering protein, polypeptide or peptide drugs and a production method for the same, and a...
The present invention relates to a macromolecule for delivering protein, polypeptide or peptide drugs and to a production method for the same, as well as to a...
US-9,603,930 Liquid bendamustine formulation
The present invention provides stable bendamustine-containing pharmaceutical compositions suitable for long term storage. The compositions include bendamustine,...
US-9,603,929 Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfecton and treatment of...
The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at...
US-9,603,928 Medicinal composition for promoting synthesis of protoporphyrin IX
The object of the present invention is to elucidate the resistance mechanism in infections that show resistance to ALA-PDT that uses a single ALA, and to...
US-9,603,927 Combination therapies with anti-CD38 antibodies
The present invention relates to combination therapies with anti-CD38 antibodies.
US-9,603,926 Histone deacetylase (HDAC) inhibitors for the treatment of cancer
The present invention relates generally to methods for treating cancer. In one respect, the present invention relates to a method of treating a hematological...
US-9,603,925 Compositions comprising TL1A-Ig fusion protein for the regulation of T regulatory cells, and methods for their use
Compositions comprising TL1A-Ig fusion proteins and methods of their use, e.g., for the treatment of diseases and disorders associated with antigen-specific...
US-9,603,924 Bovine virus vaccines that are liquid stable
The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, and a sugar alcohol. The present invention also discloses...
US-9,603,923 Universal carrier for targeting molecules to GB3 receptor expressing cells
The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the...
US-9,603,922 Modulation of NKT cell activity with antigen-loaded CD1d molecules
The invention is directed to methods of modulating an immune response in an animal, comprising administering a composition comprising one or more soluble CD1d...
US-9,603,921 Virosome particles comprising antigens from influenza virus and hepatitis b virus
The present invention provides a virosome comprising a virosomal membrane comprising at least one lipid and envelope proteins of an enveloped virus and of the...
US-9,603,920 Compositions and methods for treating influenza
The present application provides compositions and methods useful for treating influenza. As described herein, the compositions and methods are based on the...
US-9,603,919 Method for prophylaxis of influenza using vaccine for intranasal administration
The present invention provides a vaccine composition for transnasal mucous membrane administration, which contains an influenza virus antigen, polyriboinosinic...
US-9,603,918 Vaccine formulation
The present invention relates to immunological compositions and vaccines that target diseases caused by infection with Streptococcus pyogenes. In particular,...
US-9,603,917 Immunologically active compositions
This invention provides a microparticle carrier system comprising of one or more proteins, peptides, nucleic acids, carbohydrates, lipids or other bioactive...
US-9,603,916 Treatment and prevention of malaria
There are provided antigens, vectors encoding the antigens, and antibodies and other binding compounds to the antigens and uses thereof in the prevention or...
US-9,603,915 Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection
Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or morality...
US-9,603,914 Mutant strains of Neospora and uses thereof
A mutant strain of Neospora spp, in which the function of the NcMIC3 protein and/or the function of the NcMIC1 protein is suppressed, and uses thereof in a...
US-9,603,913 Globo H and related anti-cancer vaccines with novel glycolipid adjuvants
An immunogenic composition containing a glycan conjugate including a carrier protein, and a glycan including Globo H, an immunogenic fragment thereof, or...
US-9,603,912 Cancer therapy
An agent that stimulates antiviral immunity may be used, for the treatment of cancer. A product comprising an immunostimulant and a vector comprising a...
US-9,603,911 Ribotoxin molecules derived from sarcin and other related fungal ribotoxins
The present application relates to modified T cell epitopes derived from fungal ribotoxins, including a-sarcin, clavin, gigantin, mitogillin, and restrictocin,...
US-9,603,910 Pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds,...
The present invention concerns new compositions containing hyaluronic acid or the derivatives thereof in association with the proteolytic enzyme collagenase...
US-9,603,909 Composition capable of improving stability of bacteriophage lysin proteins
The present invention relates to a composition for improving the stability of bacteriophage originated lysin proteins greatly even when the composition contains...
US-9,603,908 Subcutaneous administration of iduronate-2-sulfatase
The present invention provides, among other things, compositions, kits and methods for subcutaneous delivery of lysosomal enzymes for effective treatment of...
US-9,603,907 Dry powder formulations of dNase I
DNase I formulations for pulmonary administration and, more particularly, but not exclusively, a dry powder formulation comprising, as an active ingredient,...
US-9,603,906 Inhalable liquid formulations of DNase I
An inhalable pharmaceutical composition for pulmonary administration comprising human DNase I and a liquid carrier and, more particularly, but not exclusively,...
US-9,603,905 Intranasal insulin administration for the minimization of anesthesia-induced memory loss
Intranasal administration of insulin for a predetermined period prior to anesthesia significantly prevented anesthesia-induced tau hyperphosphorylation and...
US-9,603,904 Treating diabetes melitus using insulin injections with less than daily injection frequency
The present invention relates to an insulin derivative for the treatment of a condition or disease where administration of insulin will be of benefit,...
US-9,603,903 Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as...
US-9,603,902 Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as...
US-9,603,901 Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as...
US-9,603,900 Use of PACAP for the treatment of viral infections in aquatic organisms
The present invention relates to the use of pituitary adenylate cyclase activating polypeptide (PACAP) in the treatment of viral diseases and infectious...
US-9,603,899 PDGF induced cell homing
Provided is a method of causing a cell to migrate to a scaffold. Also provided is a method of treating a mammal that has a tissue defect. Further provided is a...
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