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Patent # Description
US-9,603,848 Modulation of chemosensory receptors and ligands associated therewith
The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test...
US-9,603,847 Compositions and uses thereof
Compositions and their use in the treatment or prevention of hyperglycemia and related diseases or disorders are disclosed.
US-9,603,846 Process for the preparation of apixaban
A crystalline Form N-1 of apixaban substantially free from one or more of: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-t- ...
US-9,603,845 Prophylactic agent and/or therapeutic agent for stress urinary incontinence
An object to be solved by the present invention is to provide a superior prophylactic agent and/or therapeutic agent for stress urinary incontinence. The...
US-9,603,844 Compositions and methods for treating mammary tumors
The present invention provides methods of inhibiting abnormal growth of cells, with the methods comprising contacting the cells with at least one of the...
US-9,603,843 Kits and methods for treating post traumatic stress disorder (PTSD) and hot flashes
The present invention is directed to kits and methods for the treatment of a patient suffering from post-traumatic stress disorder (PTSD) and/or hot flashes by...
US-9,603,842 Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease
The present invention relates to a pharmaceutical composition or a functional health food comprising a verbenone derivative and pharmaceutically acceptable...
US-9,603,841 Vector delivery-based microbicides
A new class of anti-microbial agents and methods for preventing or reducing the risk of sexually transmitted infections and/or diseases is provided. Preferably,...
US-9,603,840 Treatment using dantrolene
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for...
US-9,603,839 Thioredoxin protein inhibitors and uses thereof
A method of treating a fungal infection in a subject including administering to the subject a therapeutically effective amount of a thioredoxin protein...
US-9,603,838 RORgammaT inhibitors
The present invention relates to compounds according to Formula I ##STR00001## or a pharmaceutically acceptable salt or solvate thereof. Such compounds can be...
US-9,603,837 IPA as a therapeutic agent and a biomarker for disease risk for Huntington's disease
Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
US-9,603,836 Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors
The present invention relates to compound of Formula I ##STR00001## or pharmaceutically acceptable enantiomers, salts, solvates or prodrugs thereof. The...
US-9,603,835 Use of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methylpropyl]amino-3,4-dihydro- -2H-1,5-benzoxathiepine for treating...
The present invention relates to the use of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methyl-propyl]amino-3,4-dihydro-2H-1- ,5-benzoxathiepine or one of the...
US-9,603,834 1,2- bis-sulfonamide derivatives as chemokine receptor modulators
The present invention relates to novel bis-sulfonamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as...
US-9,603,833 Benzene or thiophene derivative and use thereof as VAP-1 inhibitor
The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment...
US-9,603,832 Substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives and their use as sodium and/or calcium channel...
Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I) ##STR00001## wherein X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3, R'.sub.3 R.sub.4,...
US-9,603,831 Artemisinin and its derivatives for use in the treatment of kidney disease
The present invention relates compounds according to Formula (I) wherein R.sup.1 and R.sup.2 are independently H or an optionally substituted group selected...
US-9,603,830 Compositions and methods for preventing and recovery from detrimental effects of alcohol consumption
Disclosed are compositions, devices, and methods to prevent and recover from detrimental effects of alcohol consumption, including significant undesirable...
US-9,603,829 HSP90 inhibitors with modified toxicity
The invention provides 19-substituted geldanamycin derivatives, and pharmaceutically acceptable salts thereof that are potent Hsp90 binding agents useful for...
US-9,603,828 Sulforaphane isolation and purification
The present invention relates to methods of isolating and purifying sulforaphane. More specifically, the present invention relates to methods of isolating and...
US-9,603,827 Method for preventing and/or treating hairy wart disease
Provided is a novel method for preventing and/or treating hairy wart disease which is a hoof and leg disease of ungulates. The method is carried out by...
US-9,603,826 Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular,...
US-9,603,825 Compositions and methods of use of phorbol esters
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of cytopathic diseases. Cytopathic...
US-9,603,824 Compositions and methods for controlling infections
The invention features methods of inhibiting the growth of, or killing, fungal and certain bacterial microorganisms with one or more of a family of...
US-9,603,823 Use of medium chain triglycerides for the treatment and prevention of Alzheimer's disease and other diseases...
Methods and compositions for treating or preventing, the occurrence of senile dementia of the Alzheimer's type, or other conditions arising from reduced...
US-9,603,822 Therapeutic compositions
Ingenol angelate is a potent anticancer agent, and can be stabilised by dissolving it in an aprotic solvent in the presence of an acidic buffer.
US-9,603,821 Inhibitor of .tau. protein phosphorylation
8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid has a protein tyrosine phosphatase 1B (PTP1B) inhibitory action, an Akt activating action, a...
US-9,603,820 Ornithine aminotransferase inhibition with GABA analogues for treatment of hepatocellular carcinoma
Therapeutic methods relating to the use of GABA-AT inhibitor compounds for the treatment of hepatocellular carcinoma.
US-9,603,819 Substituted aminobutyric derivatives as neprilysin inhibitors
The present invention provides a compound of formula I'; ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, X and n...
US-9,603,818 S isomers of alpha-methyl-hydrocinnamic acid for the treatment of blood disorders
The present intervention generally relates to compositions comprising S-isomer of alpha-methyl-hydrocinnamic acid for the treatment and/or prevention of blood...
US-9,603,817 Methods, compositions, and kits for treating pain and pruritis
The invention features a method for inhibiting one or more voltage-gated ion channels in a cell by contacting the cell with (i) a first compound that activates...
US-9,603,816 Process
The present invention relates to a process for the preparation of S-[2-[1-(2 -ethylbutyl)cyclohexylcarbonylamino]-phenyl] 2-methylthiopropionate which is useful...
US-9,603,815 Method for the treatment of Dravet syndrome
A method of treating and/or preventing Dravet Syndrome in a patient such as a patient previously diagnosed with Dravet Syndrome, by administering an effective...
US-9,603,814 Method for the treatment of Dravet syndrome
A method of treating and/or preventing Dravet Syndrome in a patient such as a patient previously diagnosed with Dravet Syndrome, by administering an effective...
US-9,603,813 Visual performance and/or macular pigmentation
Disclosed is a composition comprising MZ for use as a dietary supplement or food additive for oral consumption for improving the visual performance of a human...
US-9,603,812 Treatment of autistic spectrum disorder
A method for treating a patient having ASD is disclosed. The method includes administering to the patient a therapeutically effective amount of an alpha-2...
US-9,603,811 Pharmaceutical compositions of carotenoid chylomicrons
The present invention provides pharmaceutical compositions comprising a chylomicron and a carotenoid. The present invention also provides pharmaceutical...
US-9,603,810 Nanoimprinting of silk fibroin structures for biomedical and biophotonic applications
The present invention provides for photonic nanoimprinted silk fibroin-based materials and methods for making same, comprising embossing silk fibroin-based...
US-9,603,809 Methods of treatment of attention deficit hyperactivity disorder
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms...
US-9,603,808 Method of treatment of attention deficit hyperactivity disorder
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms...
US-9,603,807 Enteral administration of sorbent polymer for treatment and prophylaxis of inflammation
The invention provides a method of ameliorating inflammation in a patient involving administering to the patient a therapeutically effective dose of composition...
US-9,603,806 Pharmaceutical compositions for the treatment of Helicobacter pylori
Single oral solid dosage form comprising an immediate release first dosage composition having at least two antibiotic agents and a delayed release second dosage...
US-9,603,805 Easily dosable solid preparation
It has been desired to develop a coating composition, which is used for an orally-administered preparation having an improved administering property, and/or an...
US-9,603,804 Solid pharmaceutical composition
[Problem] To provide a solid pharmaceutical composition which contains a compound represented by general formula (1) or a salt thereof and suppresses...
US-9,603,803 Process for preparing spray dried formulations of ...
This invention relates to a process for producing a spray-dried powder comprising microcrystalline cellulose in a solid dispersion of the anti-HIV compound...
US-9,603,802 Extrusion
The invention relates to a process for preparing a controlled release pharmaceutical extrudate using a melt extruder, wherein the melt extruder comprises a...
US-9,603,801 Bioerodible silicon-based compositions for delivery of therapeutic agents
The invention comprises a composition comprising a bioerodible porous silicon-based carrier material wherein the carrier material carries at least one large...
US-9,603,800 Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels
Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions...
US-9,603,799 Liposomal vaccine adjuvants and methods of making and using same
A vaccine adjuvant composition comprising: a lipid selected from the group consisting of: dipalmitoyl phosphatidlcholine (DPPC), dipalmitoyl ...
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