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Patent # Description
US-9,611,510 Composition and methods related to modification of 5-methylcytosine (5-mC)
The present invention relates to methods and compositions for detecting, evaluating, and/or mapping 5-methyl-modified and/or 5-hydroxylmethyl-modified cytosine...
US-9,611,509 Materials and methods for detection of nucleic acids
Assays using non-natural bases are described. In one embodiment, the method involves contacting a sample suspected of containing the target nucleic acid with a...
US-9,611,508 Processes for detecting or quantifying nucleic acids in a library
This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes...
US-9,611,507 Arrays of microparticles and methods of preparation thereof
This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized...
US-9,611,506 Reaction mixtures for forming cDNA from an RNA template
This invention relates to a process for synthesis of a cDNA in a sample, in an enzymatic reaction, whereby the process comprises the steps: simultaneous...
US-9,611,505 Application of oligo-DT molecules to avoid generation of high molecular PCR products induced by poly-A carrier
During RNA isolation carrier nucleic acids such as polyA-RNA are used in order to increase the yield of the isolated RNA. The carrier nucleic acids may lead to...
US-9,611,504 Methods of measuring analytes that include a test element quality measurement based upon intrinsic luminescence...
An analytical apparatus is disclosed for detecting at least one analyte in a sample, where in an analyte measurement at least an electrical or optical property...
US-9,611,503 Escherichia coli cell line with thyA knockout and folA knockout
The objective of this invention is to create a double thyA folA knockout Escherichia coli (E. coli) strain for antifolate screening against DHFR of malaria and...
US-9,611,502 Method for simultaneously measuring activity of various enzymes by using multi-wavelength absorption single channel
A method for simultaneously measuring the activities of multiple kinds of enzymes in single channel through concimitantly monitoring multiple wavelength...
US-9,611,501 Method and device for rapid detection of bacterial antibiotic resistance/susceptibility
Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful...
US-9,611,500 Method for detecting the presence of the viable cells in an endodontic sample
A method and apparatus for detecting the presence of the viable cells in an endodontic sample in or taken from an endodontic cavity in the tooth, such as the...
US-9,611,499 Method for producing soluble recombinant interferon protein without denaturing
The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant...
US-9,611,498 Method for producing stevioside compounds by microorganism
The present invention provides a method for producing stevioside compounds by microorganism, comprising carrying out heterologous biosynthesis of stevioside...
US-9,611,497 Crude biological derivatives competent for nucleic acid detection
The invention relates to methods for the detection of a specific sequence of RNA in a cell or tissue sample. The invention also relates to methods to...
US-9,611,496 Processes for extracting carbohydrates from biomass and converting the carbohydrates into biofuels
A process for extracting carbohydrates from biomass and creating bioalcohol from the extracted carbohydrates. Subjecting the biomass to acid or alkali...
US-9,611,495 Bacterial cellulose and bacterium producing it
[Problem] To provide a bacterial cellulose which is highly dispersible in a liquid, shows excellent molding properties and high miscibility with other materials...
US-9,611,494 Use of carbonium ion scavengers in the treatment of lignocellulosic biomass
The disclosure describes a process for the production of a cellulosic feedstock for enzymatic hydrolysis and/or a lignin fraction for chemicals production,...
US-9,611,493 Method for biomass hydrolysis
Methods and systems for biomass hydrolysis are disclosed. The methods use wash liquor in a sequencing process to maximize sugar yields, particularly C.sub.5...
US-9,611,492 Use of vinasse in the process of saccharification of lignocellulosic biomass
The use of stillage in a saccharification/fermentation process of lignocellulosic biomasses, regardless of the form of the biomasses and regardless of the use...
US-9,611,491 Biosynthetic pathway for heterologous expression of a nonribosomal peptide synthetase drug and analogs
The present invention is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention also...
US-9,611,490 Biological method for producing cis-5-hydroxy-L-pipecolic acid
A method for producing cis-5-hydroxy-L-pipecolic acid is described. A gene recombinant microorganism enabling direct production of cis-5-hydroxy-L-pipecolic...
US-9,611,489 Enzymatic omega-oxidation and omega-amination of fatty acids
The invention relates to a method for oxidizing a fatty acid or an ester thereof of formula (I) H3C --(CH2)n-COOR, wherein R is selected from the group that...
US-9,611,488 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and...
US-9,611,487 Cell-free system for converting methane into fuel and chemical compounds
The present disclosure relates, in some aspects, to cell-free methods and systems for large-scale conversion of methane to isobutanol, comprising combining, in...
US-9,611,486 Constructs and method for regulating gene expression or for detecting and controlling a DNA locus in eukaryotes
The present invention concerns constructs based on sequences derived from the partitioning system of plasmid and chromosomal DNA of bacteria, such as eukaryotic...
US-9,611,485 Polynucleotide and polypeptide sequences associated with herbicide tolerance
This invention relates generally to the detection of genetic differences among soybeans. More particularly, soybean quantitative trait loci (QTL) associated...
US-9,611,484 In vivo assembly of transcription units
Methods of providing gene suppression DNA in a eukaryotic organism comprising introducing a first DNA segment and at least one second DNA segment into the...
US-9,611,483 Viral based transient-expression vector system that allows multiple applications
Disclosed herein are viral vectors suitable for transfection into woody trees for purposes of delivering and expressing beneficial genes. Specifically...
US-9,611,482 Activity of Fe-S cluster requiring proteins
The present invention is related to a recombinant host cell, in particular a yeast cell, comprising a dihydroxy-acid dehydratase polypeptide. The invention is...
US-9,611,481 Chimeric polynucleotides and polypeptides enabling the secretion of a polypeptide of interest in combination...
The present invention provides a chimeric polypeptide comprising a plurality of polypeptide domains that are capable of being secreted in combination with...
US-9,611,480 Means and methods for counteracting, delaying and/or preventing adverse energy metabolism switches in heart disease
The invention relates to the fields of molecular biology and medicine, more specifically to treatment and prevention of heart disease. The invention provides...
US-9,611,479 Crosslinked nucleoside and nucleotide
Disclosed are bridged nucleosides and nucleotides. The nucleosides of the present invention have a 2',4'-bridged structure and are represented by formula I...
US-9,611,478 Synthetic mimics of miR-124
Embodiments concern methods and compositions involving miR-124 mimics. In some embodiments, there are double-stranded RNA molecules with modified nucleotides...
US-9,611,477 Treatment of tristetraproline (TTP) related diseases by inhibition of natural antisense transcript to TTP
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Tristetraproline (TTP), in particular, by...
US-9,611,476 Cancer treatment methods using remote conditioning
Cancer treatment methods comprising a step of applying remote conditioning to the cancer subject, for example remote ischemic conditioning via several episodes...
US-9,611,475 Prophylactic and/or therapeutic agent for inflammatory disease, and method for screening prophylactic and/or...
Provided are a novel prophylactic and/or therapeutic drug for an inflammatory disease and a method for searching for the same. A prophylactic and/or therapeutic...
US-9,611,474 Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof
Provided herein are double stranded nucleic acid molecules, compositions comprising same and methods of use thereof for the treatment of a subject wherein...
US-9,611,473 Double-stranded nucleic acid compounds
The present invention provides double-stranded RNA (dsRNA) compounds comprising a sense and antisense strand, wherein at least one strand is conjugated to a...
US-9,611,472 Compositions for RNA interference and methods of use thereof
The present invention provides compositions for RNA interference and methods of use thereof. In particular, the invention provides single-stranded small...
US-9,611,471 Antisense oligonucleotide directed removal of proteolytic cleavage sites from proteins
Described are means and methods for removing a proteolytic cleavage site from a protein, the method comprising providing a cell that expresses pre-mRNA encoding...
US-9,611,470 REF nuclease for site-specific REF-mediated DNA cleavage
Purified Ref polypeptides with increased nuclease site-specific targeting activity, recombinant nucleic acids and cells for expression of such Ref polypeptides,...
US-9,611,469 Thermostable phytase variants
The present invention relates to a method for producing phytase variants which has at least 74% identity to a phytase derived from Citrobacter braakii and...
US-9,611,468 Engineered phenylalanine ammonia lyase polypeptides
The present invention provides engineered phenylalanine ammonia-lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the...
US-9,611,467 Subcutaneous administration of ADAMTS13
This invention relates to methods of subcutaneous administration of ADAMTS13 formulations to a treat a disease or condition associated with ADAMTS13 and VWF...
US-9,611,466 Modified enterokinase light chain
The present invention is related to novel mammalian enterokinase analogues such as mammalian enterokinase light chain analogues and methods of making such. Also...
US-9,611,465 Pharmaceutical composition containing core factor involved in proliferation and differentiation of central...
With an aim to provide a novel factor inducing proliferation of neural stem cells and differentiation of these cells into nerve cells, a pharmaceutical...
US-9,611,464 Thermostable .beta.-xylosidase belonging to GH family 3
A thermostable .beta.-xylosidase including a .beta.-xylosidase catalytic domain, the .beta.-xylosidase catalytic domain including: (A) a polypeptide including...
US-9,611,463 Cellobiohydrolase variants and polynucleotides encoding same
The present invention relates to variants of a parent cellobiohydrolase II. The present invention also relates to polynucleotides encoding the variants; nucleic...
US-9,611,462 Endoglucanase 1B (EG1B) variants
The present invention provides endoglucanase 1b (EG1b) variants suitable for use in saccharification reactions. The present application further provides...
US-9,611,461 Enterobacteriaceae bacteria exhibiting increased L-cysteine producing ability
L-cysteine can be produced inexpensively and efficiently by using a bacterium belonging to the family Enterobacteriaceae modified to reduce activity of...
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