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Patent # Description
US-9,657,004 Pyruvate kinase M2 modulators, therapeutic compositions and related methods of use
Compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that...
US-9,657,001 Compounds and uses
There is provided compounds of formula I, ##STR00001## wherein E.sup.1, E.sup.2, E.sup.3, E.sup.4, L.sup.1, Y.sup.1, Y.sup.2, Y.sup.3, R.sup.a and z have...
US-9,656,999 Therapeutically active compounds and their methods of use
Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.
US-9,656,993 Crystalline forms of a biphenyl compound
The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piper- idin-4-yl...
US-9,656,992 Pyrimidine compounds for the treatment of hepatitis C
The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The...
US-9,656,991 Inhibitors of glutaminyl cyclase
Compounds of formula (I), combinations and uses thereof for disease therapy, ##STR00001## or a pharmaceutically acceptable salt, solvate or polymorph thereof,...
US-9,656,990 Cathepsin cysteine protease inhibitors
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and...
US-9,656,989 2-pentafluorosulfanyl (SFS) mefloquine derivatives, formulations, methods of making, and uses thereof
Provided herein are pentafluorosulfanyl (SF.sub.5) mefloquine derivatives, formulations, methods of making the SF.sub.5 derivatives, and uses thereof.
US-9,656,988 Inhibitors of Bruton's tyrosine kinase
Disclosed herein are reversible and irreversible inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the...
US-9,656,987 Process for preparing 3-[(S)-7-bromo-2-((2-oxopropyl)amino)-5-pyridin-2-yl-3H-1,4-benzodiazepin- ...
A process for preparing 3-[(S)-7-bromo-2-(2-oxo-propylamino)-5-pyridin-2-yl-3H-1,4,-benzodiazepin- -3-yl]propionic acid methyl ester at a high conversion rate...
US-9,656,986 Compositions comprising TPGS-750-M
In one embodiment, the present application discloses mixtures comprising (a) water in an amount of at least 1% wt/wt of the mixture; (b) a transition metal...
US-9,656,985 Surfactant-enabled transition metal-catalyzed chemistry
In one embodiment, the present application discloses mixtures comprising (a) water in an amount of at least 1% wt/wt of the mixture; (b) a transition metal...
US-9,656,984 PI3K/AKT/mTOR inhibitors and pharmaceutical uses thereof
The invention relates to new PI3K/AKT/m TOR inhibitors and their use for the prevention and/or the treatment of a disease selected from the group consisting of:...
US-9,656,983 Process for starting up a gas phase oxidation reactor
A process for preparing carboxylic acids and/or carboxylic anhydrides by gas phase oxidation of aromatic hydrocarbons, in which a gas stream comprising at least...
US-9,656,982 Acid dianhydride, method for preparing same, and polyimide prepared therefrom
The present invention relates to a novel acid dianhydride, a method for preparing the same, and a polyimide prepared therefrom. More specifically, the acid...
US-9,656,976 Mediator for test sensor
A method of forming a 3-phenylimino-3H-phenothiazine or a 3-phenylimino-3H-phenoxazine mediator includes providing a first reactant including phenothiazine or...
US-9,656,975 Bicyclo[3.2.1]octyl amide derivatives and uses of same
The present invention provides bicyclo[3.2.1]octyl amide derivatives of formula (I): ##STR00001## wherein L, R.sup.1 and R.sup.2 are as defined herein, or a...
US-9,656,974 Oxazine derivatives
The present invention provides, for example, a compound mentioned below as a medicament for treating or preventing the diseases induced by production, secretion...
US-9,656,973 Processes for preparing linezolid
Processes and intermediates for preparing linezolid, and pharmaceutically acceptable salts thereof, are described herein.
US-9,656,972 Compounds for treatment of cystic fibrosis
Described herein are compounds, compositions, and methods of their use for the treatment of cystic fibrosis.
US-9,656,971 COMT inhibitors
The present invention relates to compounds of formula ##STR00001## wherein the substituents are described in claim 1 and to the pharmaceutically acceptable...
US-9,656,970 5-(trifluoromethyl)pyrimidine derivatives and method for producing same
Provided are 5-(trifluoromethyl)pyrimidine derivatives useful as intermediates for pharmaceuticals and agrochemicals and as intermediates for electronic...
US-9,656,969 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound
Provided is a polymer film containing at least one of a compound represented by formula (1) of hydrates, solvates, or salts thereof. Y is a methine group or...
US-9,656,968 Pyrimidines as sodium channel blockers
The present disclosure provides substituted pyrimidine compounds of Formula (I), and the pharmaceutically acceptable salts, prodrugs, and solvates thereof,...
US-9,656,964 Method for producing carboxamides
The present invention relates to a process for the preparation of carboxamide derivatives of formula (I) R N O N N CF2H C H3F ##STR00001## starting from...
US-9,656,962 Ring-contracted morphinans and the use thereof
The application is directed to compounds of Formula (I) or (IA) and pharmaceutically acceptable salts and solvates thereof, wherein R.sup.1 R.sup.2, R.sup.3 and...
US-9,656,956 Benzene, pyridine, and pyridazine derivatives
Disclosed are compounds and pharmaceutically acceptable salts of Formula I ##STR00001## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7,...
US-9,656,942 Method of manufacturing diethyl carbonate
A method manufactures diethyl carbonate by reaction distillation where transesterification and distillation are simultaneously performed in a multistage...
US-9,656,935 Polyol-ether compound and method for producing the same
A method for producing a polyol-ether compound, wherein a compound represented by the following formula (1) is subjected to hydrogenation reduction in the...
US-9,656,926 Self-consuming materials
A self-consuming structure is disclosed that is formed from a self-consuming composition based on an epoxy or polyurethane having fuel and/or oxidizer...
US-9,656,922 Coal refuse remediation process
A coal refuse remediation process is described. The process includes providing coal refuse and blending a slag with at least a portion of the coal refuse to...
US-9,656,916 Dimensionally stable geopolymer composition and method
A method for making geopolymer cementitious binder compositions for cementitious products such as concrete, precast construction elements and panels, mortar,...
US-9,656,914 Rheology modifying agents for slurries
Rheology modifying agents and methods of modifying the rheology of a slurry are disclosed, in addition to methods for the prevention of fouling. The slurry can...
US-9,656,913 Transparent laminate which inhibits puncture by projectiles
A transparent laminate is provided that includes at least one chemically prestressed pane having a thickness, a compressive stress (CS) of a surface layer, a...
US-9,656,910 Methods of fabricating glass articles by laser damage and etching
Methods of forming a glass article are disclosed. In one embodiment, a method of forming a glass article includes translating a pulsed laser beam on a glass...
US-9,656,908 Inorganic adhesive composition and hermetic sealing method using same
The present invention relates to an inorganic adhesive composition and to a hermetic sealing method, and more specifically relates to an inorganic adhesive...
US-9,656,903 Method of manufacturing high strength glass fibers in a direct melt operation and products formed there from
A method of forming high strength glass fibers in a glass melter substantially free of platinum or other noble metal materials, products made there from and...
US-9,656,902 Method of manufacturing preforms for optical fibres having low water peak
A method of manufacturing at least one optical fibre preform comprising: providing a plurality of partially porous intermediate preforms, each partially porous...
US-9,656,900 Methods to fabricate nano-macro porous glass using a water soluble pore former
Provided herein are methods for preparing nano-macroporous glass articles, such as bioscaffolds, from starting materials such as phosphosilicate glasses made by...
US-9,656,898 Automatic substitution of blank molds in the manufacture of hollow glass products
A process for manufacturing a hollow glass product using an I.S. machine and a robot that can move alongside blank molds of the I.S. machine, wherein the robot...
US-9,656,893 Simultaneous anoxic biological phosphorus and nitrogen removal with energy recovery
Methods and systems are provided for treating wastewater to simultaneously remove nitrogen, carbon, and phosphorus, while recovering energy in the form of...
US-9,656,892 Leach field form and method of use
A leach field form comprising: a container with an open bottom and an open top, and four exterior walls of a first height, and at least one interior wall; at...
US-9,656,890 Treatment of arsenic contaminated soil and water
The present invention is directed to a method for the treatment of an environmental medium contaminated with arsenic, comprising treating such medium with an...
US-9,656,889 Inhibitors for organics solubilized in produced water
A surface active compound is supplied into contact with an oilfield production fluid that comprises a mixture of water and oil including water soluble organics....
US-9,656,885 Systems and methods for ion separation in an aqueous solution
Systems and methods for providing a deionization chamber having a plurality of electrodes corresponding to a plurality of register levels thereby forming a...
US-9,656,884 Bipolar cell for a reactor
A bipolar cell for a reactor for treatment of electrolyte such as waste water and effluent or for electrosynthesis comprises end electrodes and at least one...
US-9,656,883 Forward osmosis system comprising solvent separation by means of membrane distillation
The invention relates to a system for separating a product contained as solvent in a solution to be processed, comprising at least one forward osmosis device...
US-9,656,882 Water treatment composition and method of using same
A water treatment composition includes a water soluble film formed into a sealed pouch. The pouch contains a composite of a phosphate removing substance, a...
US-9,656,879 Method for treating titanium-containing feedstock
A method for producing titanium tetrachloride is provided, in which valuable materials such as unreacted titanium-containing raw material, carbon raw material...
US-9,656,877 Preparing layered double hydroxide nanostructures
Provided is a method for manufacturing nanostructured layered double hydroxides (LDHs) having a uniform size distribution with homogenous nano-disc morphology....
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