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Patent # Description
US-9,655,959 Adenylate cyclase deficient bordetella strains
A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination...
US-9,655,957 Rodent plasmodium parasites as platforms for a whole-organism malaria vaccine
A method for inducing protective immunity in a vertebrate host against malaria, by administering to the host a live rodent Plasmodium organism and exploiting...
US-9,655,953 Targeted protein replacement for the treatment of lysosomal storage disorders
The present invention relates to compositions and methods for delivering lysosomal proteins. The compositions and methods described herein permit the targeted...
US-9,655,952 Blood substitute composition and method of use
The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in...
US-9,655,950 Activation of myeloid-derived suppressor cells as a predictor of patient response to interferon-A therapy
The present invention relates to methods and materials for more effectively treating patients with interferon. It is based on the discovery that clinical...
US-9,655,948 Non-surgical, localized delivery of compositions for placental growth factors
Described herewith are compositions comprising placental growth factors and methods for non-surgical, localized delivery thereof. The composition is delivered...
US-9,655,945 Treatment of ascites
A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition...
US-9,655,940 Formulation of a mixture of free-B-ring flavonoids and flavans as a therapeutic agent
The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds--Free-B-ring flavonoids and...
US-9,655,938 Compositions of polymeric myrcene
The invention relates to compositions and formulations comprising polymeric myrcene. More particularly, the invention relates to compositions comprising an...
US-9,655,933 Filamentous bacteriophage as an angiogenesis modulator
The invention relates to a filamentous bacteriophage, carrying bacterial Lipopolysaccharide (LPS) endotoxin on its surface, for use in treating cancer and in...
US-9,655,932 Composition and method for preventing or treating gout or hyperuricemia
A composition composed of a Lactobacillus bacterium, Bifidobacterium longum, and xylooligosaccharide is provided for use in reducing uric acid levels in the...
US-9,655,928 Spinal disc regenerative composition and method of manufacture and use
The present invention provides a novel way to replenish the disc using retooled disc compositions to repair degenerative discs. There is no better source of...
US-9,655,924 System for treating ear infections
Disclosed herein are compositions for treatment of ear infection (such as bacterial and/or yeast infection) in human or veterinary subjects. In some embodiments...
US-9,655,920 Amine polymers for use as bile acid sequestrants
The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding...
US-9,655,917 Immobilization of an active agent on a substrate using compounds including trihydroxyphenyl groups
The invention provides methods of immobilizing an active agent to a substrate surface, including the steps of, providing a substrate, contacting the substrate...
US-9,655,916 Compositions for external application, containing adenosylcobalamin for improvement of skin diseases
The present invention relates to a composition for external application for improving a skin disease (e.g. psoriasis). The composition contains ...
US-9,655,915 Phosphoramidate derivatives of 5-fluoro-2'-deoxyuridine for use in the treatment of cancer
Phosphoramidate derivatives of 5-fluoro-2'-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the...
US-9,655,913 Anti-esophageal cancer compound and method of use thereof
The present invention relates to the bioactive components with the anti-proliferative property. In particular, the invention relates to one flavonol compound...
US-9,655,911 Antidepressant combination drug
The combined use of 1,2-dilinoleoyl-sn-glycero-3-phosphocholine and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine affords a superior anti-depressive action,...
US-9,655,902 Guanidine derivatives for the treatment of hepatitis C
Compounds of Formula I, including pharmaceutically acceptable salts thereof, are set forth, in addition to compositions and methods of using these compounds....
US-9,655,895 Morphinan compounds
This invention relates to novel morphinan compounds and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a...
US-9,655,887 Pharmaceutical composition and the use thereof, and application regime of said pharmaceutical composition for...
The invention relates to a pharmaceutical composition for non-hormonal, on-demand contraception and to processes for preparing this pharmaceutical composition....
US-9,655,886 Substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles, methods for use thereof
The present invention relates to a method of antagonizing a 5-HT.sub.6 serotonin receptor, comprising administering to the cell a compound of formula 1.2, or a...
US-9,655,885 Amorphous mirabegron and processes for crystal forms of mirabegron
Aspects of the present invention relate to amorphous form of mirabegron, amorphous solid dispersion of mirabegron, process for its preparation, processes for...
US-9,655,883 Pharmaceutical composition
A topical composition comprises at least 5-wt % metronidazole or a pharmacologically acceptable derivative thereof in a non-aqueous vehicle. The composition may...
US-9,655,880 Azetidine estrogen receptor modulators and uses thereof
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds...
US-9,655,879 Heteroarylcarboxylic acid ester derivative
Compounds represented by the following formula (I); ##STR00001## wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors...
US-9,655,878 Composition comprising coumestrol or a bean extract containing coumestrol
The present invention relates to a composition which comprises as an active ingredient coumestrol or a bean extract containing coumestrol, whereby adipocyte...
US-9,655,877 Therapeutic methods for treating inflammation and immune system disorders
The subject invention provides novel and advantageous materials and methods for treating neuroinflammation, neurodegenerative disease, and cerebrovascular...
US-9,655,876 Liquid composition containing taxane-based active ingredient, process for producing same, and liquid preparation
A liquid composition which includes a taxane-based active ingredient (a) selected from the group consisting of docetaxel and a derivative thereof; at least one...
US-9,655,875 Method of treating or preventing tumors using 1-(alkylsulfinyl)-2-isothiocyanatoalkyl-1-alkene
A method of treating or preventing human or mammalian cancer and tumor including administering to a patient or an animal in need thereof a pharmaceutical...
US-9,655,874 Method for treating eczema
A method for treating eczema including the steps of applying an isothiocyanate functional surfactant to an area affected by eczema, wherein the isothiocyanate...
US-9,655,873 Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
A method of parenterally administering a composition, the method including parenterally administering to a person a composition including at least one omega-3...
US-9,655,872 Treatment of cancer with specific RXR agonists
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating...
US-9,655,870 Homeopathic drug composition and methods of use thereof
The present invention comprises homeopathic preparations of compounds, methods for using such preparations and delivery systems for the treatment of disease...
US-9,655,865 Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes
The present invention is directed to a method for treating a patient suffering from the metabolic syndrome, Type 2 diabetes, obesity, or prediabetes, comprising...
US-9,655,861 Oral pharmaceutical dosage forms
Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
US-9,655,857 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor
Described herein are pharmaceutical formulations of Bruton's tyrosine kinase (Btk) inhibitor ...
US-9,655,850 Substituted diketopiperazine analogs for use as drug delivery agents
Disclosed are drug delivery systems for the delivery of small molecule and macromolecular drugs. More particularly, disclosed are substituted analogs of...
US-9,655,846 Methods for the preparation of liposomes comprising drugs
Provided herein are methods for preparing liposomes comprising docetaxel and uses thereof. In certain embodiments, liposomes are prepared without using heat,...
US-9,655,844 Biocompatible polysaccharide-based hydrogels
Modified polysaccharides and crosslinked modified polysaccharide compositions are described. Methods of using the crosslinked modified polysaccharide...
US-9,655,841 Topical anti-inflammatory pharmaceutical composition with zileuton cream formulation
Provided herein is a zileuton cream type topical anti-inflammatory pharmaceutical composition, and more particularly, a zileuton cream type topical...
US-9,655,839 Probiotic arginolytic oral compositions and methods of making and using probiotic arginolytic oral compositions
The present disclosure provides probiotic arginolytic oral compositions, methods of making probiotic arginolytic oral compositions, and methods of using...
US-9,655,836 Sprayable composition comprising high molecular weight charged polymer
Disclosed herein are sprayable compositions comprising: a complex of (A) at least one charged (or pseudo-charged) polymer having a molecular weight of about...
US-9,655,833 Compositions and methods for inhibiting hair growth
A method for inhibiting hair growth in mammals using compositions containing FP receptor antagonists (e.g., prostaglandin F analogs that are block activation of...
US-9,655,826 Hair dye composition
A hair dye composition is characterized by containing (A) HC BLUE No. 2, (B) DISPERSE VIOLET 1, and (C) at least one of HC YELLOW No. 2 and HC YELLOW No. 4 and...
US-9,655,825 Sunscreen composition containing high levels of liposoluble UV filters
A water-releasing sunscreen composition in the form of an emulsion and process for using the composition are provided. The composition includes an aqueous phase...
US-9,655,823 Cosmetic composition
A topically administrable composition comprises an aqueous suspension (e.g. a quick-drying aqueous solution), said aqueous suspension having disposed there...
US-9,655,822 Hydrated lamellar phases or liposomes which contain a fatty monoamine or a cationic polymer which promotes...
The invention relates to novel hydrated lamellar phases or liposomes which contain either polyethylenimine, or a substance which stimulates intracellular...
US-9,655,821 Personal care composition comprising a pre-emulsified formulation
The present invention is directed to a personal care composition comprising a pre-emulsified emulsion comprising from about 0.25% to about 80% of one or more...
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