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Patent # Description
US-9,663,594 Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with...
Disclosed herein are methods of making bis(phenol) ligand compounds and transition metal bis(phenolate) compounds. The transition metal bis(phenolate) compounds...
US-9,663,593 Polymer compound for a conductive polymer and method for producing same
The present invention provides a polymer compound for a conductive polymer, containing one or more repeating units (a) represented by the following general...
US-9,663,592 Modified ethylene-vinyl alcohol copolymer, method for producing same, and use of same
Provided is a modified ethylene-vinyl alcohol copolymer, wherein the copolymer is represented by a following formula (I), contents (mol %) of a, b, and c based...
US-9,663,591 Reduction of fouling in high pressure reactors
The Application of equations of state to experimental and literature data permits the formation of a model and phase diagram(s) that show under what conditions...
US-9,663,590 Process for the (co-)polymerisation of olefins
Process for the polymerization or copolymerization of olefins by bringing the olefins into contact with a catalyst under polymerization or copolymerization...
US-9,663,589 Coagulation of biopolymers from ionic liquid solutions using CO.sub.2
Disclosed herein are processes for providing a biopolymer from a biomass or source of chitin using ionic liquids. The processes involve contacting a biomass or...
US-9,663,588 Method for concentrating fibril cellulose and fibril cellulose product
A method for concentrating fibril cellulose including subjecting aqueous fibril cellulose at a concentration of not higher than 5% to pressure filtration where...
US-9,663,587 IL-17 binding proteins
Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related...
US-9,663,586 Anti-SOD1 antibodies and uses thereof
The present invention features anti-SOD1 antibodies and methods of using the antibodies for the treatment of amyotrophic lateral sclerosis (ALS) or the...
US-9,663,585 Anti-DCLK1 monoclonal antibodies and methods of production and use thereof
Monoclonal antibodies against DCLK1 and conjugates containing these monoclonal antibodies are disclosed. Methods of producing and using these monoclonal...
US-9,663,584 Antibodies to non-functional P2X7 receptor
The present invention provides antibodies that specifically bind to P2X.sub.7 receptors and distinguish between function and non-functional P2X.sub.7 receptors,...
US-9,663,583 Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile
The present invention relates to an anti-CD19 antibody having a variant Fc region having some specific amino acid modifications relative to a wild-type Fc...
US-9,663,582 Optimized Fc variants
The present invention relates to Fc variants having decreased affinity for Fc.gamma.RIIb, methods for their generation, Fc polypeptides comprising optimized Fc...
US-9,663,581 Modified glycoproteins
Modified glycoproteins, and methods of making and using such modified glycoproteins, are described.
US-9,663,580 Antibodies against human CSF-1R and uses thereof
The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing...
US-9,663,579 Formulation for anti-.alpha.4.beta.7 antibody
Methods for achieving clinical response of Crohn's disease in a human patient are described comprising administration of an antibody that has binding...
US-9,663,578 Monoclonal antibodies against CD32b
Isolated monoclonal antibodies which bind to human CD32b and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical...
US-9,663,577 Monoclonal antibodies that bind B7H6 and uses thereof
Disclosed are monoclonal antibodies that specifically bind to the B7 family member B7H6, including antibodies capable of inhibiting the interaction of B7H6 with...
US-9,663,576 Therapeutic use of anti-CD22 antibodies for inducing trogocytosis
Disclosed are methods and compositions of anti-B cell antibodies, preferably anti-CD22 antibodies, for diagnosis, prognosis and therapy of B-cell associated...
US-9,663,575 CD47 antibodies and methods of use thereof
This invention relates generally to monoclonal antibodies that recognize CD47, more specifically to CD47 antibodies that do not cause a significant level of...
US-9,663,574 Anti-C5 antibodies having improved pharmacokinetics
The disclosure provides antibodies that are useful for, among other things, inhibiting terminal complement (e.g., the assembly and/or activity of the C5b-9 TCC)...
US-9,663,573 Methods of treating liver conditions using Notch2 antagonists
Methods and compositions for the treatment of liver conditions are provided, such methods and compositions comprising Notch2 antagonists, e.g., anti-Notch2...
US-9,663,572 Antibodies that bind both IL-17A and IL-17F
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A and IL-17F. IL-17A and IL-17F are cytokines...
US-9,663,571 Oncostatin M receptor antigen binding proteins
The invention provides anti-oncostatin M receptor-.beta. (OSMR) antigen binding proteins. e.g., antibodies and functional fragments, derivatives, muteins, and...
US-9,663,570 Single domain antibodies directed against KRAS
This invention provides compositions and methods to treat a condition or disease without the use of exogenous targeting sequences or chemical compositions. The...
US-9,663,569 Use of blocking agents of bone morphogenic protein (BMP) signalling for the treatment of neuroinflammatory and...
The invention provides pharmaceutical compositions for the treatment of neuroinflammatory or neurodegenerative diseases comprising a single or a combination of...
US-9,663,568 Antibodies that bind peptidoglycan recognition protein 1
Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's...
US-9,663,566 Soluble hybrid Fc.gamma. receptors and related methods
Disclosed are soluble hybrid Fc.gamma. receptor (Fc.gamma.R) polypeptide compositions and related methods of using such polypeptides to treat IgG-mediated and...
US-9,663,565 Insulinotropic peptide derivative with modified N-terminal charge
The present invention relates to an insulinotropic peptide derivative with a modified N-terminal charge and a pharmaceutical composition including the same....
US-9,663,564 Vectors and methods to treat ischemia
This disclosure relates to vectors, isolated cells, compositions, and methods for the treatment of critical limb ischemia and associated disorders. One aspect...
US-9,663,563 Aqueous liquid composition
The invention provides an aqueous liquid composition comprising a WT1 protein-derived cancer antigen peptide, wherein the peptide is stabilized. The aqueous...
US-9,663,562 Compositions and methods for treating cancer
Compositions comprising SEQ ID NO: 1 and methods of treating a MUC16-expressing tumor cell are described.
US-9,663,561 Methods of treatment of cancer using SRC-modulating peptides
A method for regulating Src and its downstream signaling pathway which includes binding between Src and Na+/K+-ATPase is disclosed. The Na+/K+-ATPase/Src...
US-9,663,557 Signal peptide fusion partners facilitating listerial expression of antigenic sequences and methods of...
The present invention provides nucleic acids, expression systems, and vaccine strains which provide efficient expression and secretion of antigens of interest...
US-9,663,556 Treatment of cancers with immunostimulatory HIV tat derivative polypeptides
Disclosed herein are compositions comprising a Human Immunodeficiency Virus (HIV) trans-activator of transcription (Tat) derivative polypeptide with increased...
US-9,663,555 Beta sheet tapes ribbons in tissue engineering
There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel...
US-9,663,554 Multifunctional protein molecular weight ladders
Multifunctional molecular weight protein ladders and methods of making thereof are disclosed herein that are useful for determining the molecular weight of a...
US-9,663,552 Purification method for proteins, in particular antibodies, utilizing a wash solution comprising arginine at...
The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, at pH greater than...
US-9,663,551 Solanidine-derived compounds
Novel solanidine-derived compounds, the synthesis method thereof and the uses of same in the fields of phytosanitary protection and health. In particular, the...
US-9,663,550 Method for preparing abiraterone acetate
A method for preparing abiraterone acetate. The steps are: dehydroepiandrosterone acetate and trifluoromethanesulphonic anhydride undergo a sulfonylation...
US-9,663,549 Therapeutically active 17-nitrogen substituted estratreinthiazole derivatives as inhibitors of...
The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof wherein R2 to R7 are as defined in the claims. The invention...
US-9,663,548 10-.alpha./.beta.-D-arabinofuranosyl-undecenes as potential anti-mycobacterial agents and process for the...
Disclosed herein is 10-.alpha./.beta.-D-Arabinofuranosylundecenes of general Formula (II) or pharmaceutically acceptable salts thereof as anti-mycobacterial...
US-9,663,546 Metal amides of cyclic amines
Compounds, and oligomers of the compounds, are synthesized with cyclic amine ligands attached to a metal atom. These compounds are useful for the synthesis of...
US-9,663,545 Organometallic 2-cyano-2-aminobenzoate-propyl derivates and their use as anthelmintics
The invention relates to compounds characterized by a general formula (1), ##STR00001## wherein X is a group described by a general formula ...
US-9,663,544 Organic electroluminescent materials and devices
Heteroleptic cyclometallated complexes having a 6-membered ring cyclometallated to the metal, as shown in Formula (I), are provided: ##STR00001## wherein ring...
US-9,663,543 Phosphonate compounds for treatment of complement mediated disorders
Compounds, methods of use, and processes for making inhibitors of complement factor D comprising Formula I, or a pharmaceutically acceptable salt or composition...
US-9,663,542 O-phenyl chalcone compounds and preparation method and use thereof
Disclosed are an o-phenyl chalcone compounds and preparation methods and uses thereof. The o-phenyl chalcone compounds are capable of inhibiting the aggregation...
US-9,663,541 Group 5 metal oxo-alkoxo complex, method for producing same, and method for manufacturing group 5 metal oxide film
A compound useful for the manufacture of a Group 5 metal oxide film is provided. The compound is a Group 5 metal oxo-alkoxo complex represented by the following...
US-9,663,539 Process for producing low-color and color-stable isocyanatoorganosilanes and products derived therefrom
The invention herein is directed to a process for producing isocyanatoorganosilanes having low color and improved color stability over known isocyanatosilanes...
US-9,663,538 Aluminum compound, thin-film forming raw material, and method for producing thin film
Disclosed is an aluminum compound of general formula (I) and a thin film forming material containing the aluminum compound. In formula (I), R.sup.1 and R.sup.2...
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