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Patent # Description
US-9,663,485 Tocopherol and tocopheryl quinone derivatives as correctors of Lysosomal Storage Disorders
The subject invention relates to improved tocopheryl quinone derivatives and tocopherol derivatives having improved pharmacokinetics in vivo that can, in some...
US-9,663,484 Isoflavonoid compounds and methods for the treatment of cancer
Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer...
US-9,663,483 Furanyl compounds and the use thereof
Provided herein are substituted furanyl compounds of formula (I), pharmaceutical compositions comprising the compounds, methods of their preparation, and...
US-9,663,482 Substituted piperazinyl acetohydrazide procaspase-activating compounds
The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds are of Formula I ##STR00001## The compounds and...
US-9,663,481 Phenoxy acetic acids and phenyl propionic acids as PPAR.delta. agonists
Phenoxy acetic acids and phenyl propionic acids and their use in treating type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, or...
US-9,663,480 BIS-MMF derivatives
The present invention relates to novel compounds, e.g. for use as a medicament. In particular, the present invention relates to novel medicaments, preferably in...
US-9,663,479 .gamma.-aminobutyric acid (GABA) analogues for the treatment of pain and other disorders
A compound of Formula (1) wherein R.sub.1 represents hydrogen, halo, a C1-C4 alkyl group, a C1-C4 alkylhalide group, a C1-C4 alkoxy-C2-C4 alkyl group, a C2-C4...
US-9,663,477 Synthesis and structure of 3,5-diamino-2,6-di-(tert-butyl-NNO-azoxy) pyrazine as a critical intermediate in the...
The present disclosure relates generally to a critical intermediate in a synthesis of a postulated energetic material, and more specifically relates to a...
US-9,663,476 Glycine transporter-1 inhibitors
The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the...
US-9,663,474 Heterocyclic substituted 2-amino quinazoline derivatives for the treatment of viral infections
This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use...
US-9,663,473 Benzimidazolyl-methyl urea derivatives as ALX receptor agonists
The present invention relates to benzimidazolyl-methyl urea derivatives of formula (I), ##STR00001## wherein n, D, E, R.sup.1, R.sup.2, R.sup.3, R.sup.4,...
US-9,663,472 Pyrazole compound
The present invention relates to a novel serotonin reuptake inhibitor which also exhibits 5-HT.sub.2C antagonistic action (antidepressive and anxiolytic...
US-9,663,471 Pyrazole derivatives as modulators of hepatocyte growth factor (scatter factor) activity
The present invention provides compounds having formula (I): ##STR00001## and pharmaceutically acceptable derivatives thereof, wherein R.sup.1, R.sup.2 and B...
US-9,663,470 Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
The present invention relates to compounds defined by formula I ##STR00001## wherein the variables R.sup.1, R.sup.2, R.sup.3, R.sup.4, and m are defined as in...
US-9,663,469 ROR.gamma. modulators
Described are ROR.gamma. modulators of the formula (I), or pharmaceutically acceptable salts thereof, wherein all substituents are defined herein. The invention...
US-9,663,468 2-aminoquinoline-based compounds for potent and selective neuronal nitric oxide synthase inhibition
Various 2-aminoquinoline compounds as can be used, in vivo or in vitro, for selective inhibition of neuronal nitric oxide synthase.
US-9,663,467 Alkyl-amide-substituted pyridyl compounds useful as modulators of IL-12, IL-23 and/or IFN.alpha. responses
Compounds having the following formula (I): or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, and...
US-9,663,466 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors
The present invention provides compounds of Formula (I): ##STR00001## or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the...
US-9,663,465 Acetylcholinesterase inhibitors and promnesiant serotonin 5-HT4 receptor agonists, their methods of preparation...
Compounds are provided according to Formula (I) ##STR00001## as well as their enantiomers and their racemics, their acid salts, their hydrates or their...
US-9,663,464 Carbazole derivatives acting on 5-HT7 receptor
The present invention provides a carbazole derivative represented by Formula 1: ##STR00001## wherein X is CH.sub.2 or C(O), Y is selected from...
US-9,663,463 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purpose
The object of the present invention is to provide a compound having an antagonistic action against .mu.-opioid receptors, which causes less side effects and...
US-9,663,462 Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
The present invention includes methods and compositions for the treatment and prevention of protozoal parasitic infections utilizing Diindolylmethane-related...
US-9,663,461 Method for synthesising a mercaptan by adding hydrogen sulfide to an olefin
The invention relates to a method for synthesising a mercaptan from a terminal olefin and hydrogen sulphide which comprises the following consecutive steps:...
US-9,663,460 Sulfur derivatives as chemokine receptor modulators
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as...
US-9,663,459 Preparation of surfactants via cross-metathesis
The present invention relates to compositions comprising alkene benzenes or alkene benzene sulfonates or alkylbenzenes or alkylbenzene sulfonates; methods for...
US-9,663,457 Carbamoyl hydrazine derivatives as formyl peptide modulators
The present invention relates to carbamoyl hydrazine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as...
US-9,663,456 Intermediate of tapentadol
The present invention relates to novel carbamate intermediate of formula (II), process for its preparation and process for its conversion into ...
US-9,663,455 Methods for treating attention-deficit/hyperactivity disorder
The invention is directed to a method of treating attention-deficit/hyperactivity disorder (ADHD) in a subject, comprising administering a therapeutically...
US-9,663,454 3-aryl propiolonitrile compounds for thiol labeling
The present invention relates to a process for labeling compounds comprising thiol moieties with 3-arylpropiolonitrile compounds, to 3-arylpropiolonitrile...
US-9,663,453 Metabolites and oximes with vasodilator and hypotensive activity
Semi-synthetic oximes derived from metabolites extracted from medicinal plants, Senecio nutans and Xenophyllum poposum, the method of preparation thereof and...
US-9,663,452 Method for preparing formamidines
A method for preparing formamidines of formula (I) in a single step by reducing ureas of formula (II) using silanes of formula (III), according to reaction...
US-9,663,451 Forms of co-crystals of agomelatine and p toluenesulphonic acid, a process for their preparation and...
The present invention relates to new forms of co-crystals of agomelatine and p-toluenesulphonic acid, to a process for their preparation and to pharmaceutical...
US-9,663,450 Process for the purification of melphalan
A method for the purification and preparation of melphalan that allows to obtain melphalan with purity higher than 99.5% is described.
US-9,663,449 Lipid containing formulations
Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described.
US-9,663,448 Tri-aryl compounds and compositions comprising the same
The present invention relates to a novel class of tri-aryl compounds, compositions comprising the same and processes for the preparation thereof.
US-9,663,447 Asymmetric butadiene-based charge transport compound, electrophotographic photoreceptor containing same, and...
Provided are an asymmetric butadiene-based charge transporting compound represented by one of Formula (1) and (1') as in claim 1, an electrophotographic...
US-9,663,446 Process for forming a primary, a secondary or a tertiary amine via a direct amination reaction
Disclosed is a process for preparing a primary, a secondary or a tertiary amine via the direct amination of an alcohol in the presence of a catalyst. The...
US-9,663,445 Synthesis system, rubber chemical substance for tires, synthetic rubber for tires, and pneumatic tire
The present invention provides a synthesis system that can synthesize aniline and/or styrene efficiently, a synthesis system that can synthesize butadiene...
US-9,663,444 Heteroatom containing substituted fatty acids
Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and...
US-9,663,443 Process for making tertiary aminoalcohol compounds
A process for making a tertiary aminoalcohol compound is disclosed. The process comprises using an excess amount of a carbonyl compound in a condensation step...
US-9,663,442 Stabilization of household, body-care and food products by using benzotropolone containing plant extracts...
Disclosed is the use of benzotropolone derivatives of formula ##STR00001## wherein R.sub.1, R.sub.2 and R.sub.7 independently from each other are hydrogen;...
US-9,663,441 Process for cleaning carbon dioxide-containing process gases from the preparation of vinyl acetate
The invention provides processes for cleaning carbon dioxide-containing process gases from the preparation of vinyl acetate after reaction of ethylene with...
US-9,663,440 Cross metathesis of poly-branched poly-olefins
This invention describes processes to make products by cross metathesis of functionalized or non-functionalized olefins with poly-branched poly-olefins such as...
US-9,663,439 Aildenafil citrate crystal form O, preparation method and use thereof
The invention provides a 1-[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d] pyridine-5-group)-4-ethoxy-benzenesulfonyl]-cis-3,5-dimethylpiperazine ...
US-9,663,438 Process for forming chromium propionate as an agricultural feed additive
Chromium propionate, as an animal feed supplement, is created employing chromium carbonate and propionic acid as starting materials. A quantity of chromium...
US-9,663,437 Production of acetic acid with high conversion rate
A process for producing acetic acid comprising the steps of reacting carbon monoxide and at least one of methanol and a methanol derivative in a first reactor...
US-9,663,436 Method for preparation of 4-alkoxy-1,1,1-trifluorobut-3-en-2-ones from 1,1,1-trifluoroacetone
The invention discloses a method for the preparation of 4-alkoxy-1,1,1-trifluorobut-3-en-2-ones from 1,1,1-trifluoroacetone.
US-9,663,435 Process for conversion of levulinic acid to ketones
A method for generating desired platform chemicals from feedstocks such as cellulosic biomass feedstocks containing levulinic acid by decarboxylating a feed...
US-9,663,434 Method for hydroformylating an olefin
A functionalized nanomaterial having an average particles size of less than 10 nm comprising an iron oxide nanoparticle core and a bis(diarylphosphinomethyl)...
US-9,663,433 Method of alkylating or acylating an arene
A method of alkylating or acylating an arene includes reacting the arene with an organic halide in the presence of an aprotic solvent and a catalyst of formula...
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