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Patent # Description
US-9,662,348 Compositions for controlling Varroa mites in bees
An isolated nucleic acid agent is disclosed comprising a nucleic acid sequence which downregulates expression of a gene product of a Varroa destructor mite....
US-9,662,347 Method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of age-albumin in...
The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the...
US-9,662,346 Method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by insect stings or noxious weeds or...
A method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by an insect or arthropod sting or bite, or a skin contact with a noxious weed or...
US-9,662,345 Antibiotic composition for inhalation and irrigation
An antibiotic composition for the treatment of bacterial infections, especially in the respiratory tract is provided. The antibiotic composition may include a...
US-9,662,344 Carnitine retention
A composition for influencing carnitine retention in biological tissue is disclosed. The composition comprises a carnitine substance and an agent to increase...
US-9,662,343 Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain...
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions such as...
US-9,662,342 Formulations of cyclophosphamide liquid concentrate
Cyclophosphamide containing compositions preferably in the form of solutions having extended stability are disclosed. The compositions contain cyclophosphamide,...
US-9,662,341 Multifunctional topical formulation for the treatment of acne vulgaris and other skin conditions
A two-part aqueous composition for treating skin ailments, such as acne vulgaris, includes an acidic part having salicylic acid and an .alpha.-hydroxy acid, and...
US-9,662,340 Testosterone gel compositions and related methods
Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for...
US-9,662,339 Benzodioxane inhibitors of leukotriene production for combination therapy
The present invention relates to a combination comprising compounds of formula (I): ##STR00001## wherein R.sup.1 to R.sup.3, A, X and n are as defined herein,...
US-9,662,338 Formulations of viloxazine
Modified release formulations of viloxazine and methods of administering the same are disclosed. High-drug load formulations of viloxazine are further disclosed.
US-9,662,337 Bisaryl (thio)morpholine derivatives as S1P modulators
Described are compounds that are modulators of the S1P receptors, and pharmaceutical compositions comprising the compounds. Also described are methods of using...
US-9,662,336 Pyrazolopyrimidine compounds
Compounds of formula (I) and salts thereof: ##STR00001## wherein R.sub.1 is n-C.sub.1-6alkyl or C.sub.1-2alkoxyC.sub.1-2alkyl-, R.sub.2 is halo, OH or...
US-9,662,335 Heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B] pyrimidines as janus kinase inhibitors
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of...
US-9,662,334 Sildenafil sublingual spray formulations
The invention is directed to sublingual spray formulations containing sildenafil. The invention is further directed to methods of treating male sexual...
US-9,662,333 Tetrahydropyridopyrimidine compound or salt thereof
A tetrahydropyridopyrimidine compound represented by formula (I) or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition including the...
US-9,662,332 Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections
Compounds, compositions, and methods of treatment and prevention of HIV infection are disclosed. The compounds are pyrrolo[2,3-b]pyridines and ...
US-9,662,331 3-aryl-2-((arylamino)methyl)quinazolin-4-(3H)-ones
The invention relates to novel quinazolinone compounds and their use as inhibitors of PI3 kinases, for example, PI3K.delta., for treating and/or preventing...
US-9,662,330 Aminopyrimidine derivatives for use as modulators of kinase activity
The invention provides novel heterocyclic amine compounds according to Formula (I) and their manufacture and use for the treatment of hyperproliferative...
US-9,662,329 Use of survivin antagonists in polyomavirus-related disease
A method of treating a polyomavirus (+) cancer in which survivin is upregulated in a patient is provided, comprising administering to the patient a...
US-9,662,328 Targeting human thymidylate kinase induces DNA repair toxicity in malignant tumor cells
The present invention relates to novel TMPK inhibitor and their methods of use. In particular, it relates to novel TMPK inhibitor of Formula (I) and...
US-9,662,326 Systems for treating an opioid-induced adverse pharmacodynamic response
Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient...
US-9,662,325 Use of opioid antagonists to attenuate endothelial cell proliferation and migration
The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation...
US-9,662,324 Methods and compositions for treating .beta.-thalassemia and sickle cell disease
Compounds, pharmaceutical compositions, and methods for treating anemia (.beta.-thalassemia anemia or sickle cell anemia.
US-9,662,323 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity
Compounds of formula I, defined herein, act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for treating diseases...
US-9,662,322 Laquinimod for the treatment of relapsing-remitting multiple sclerosis (RRMS) patients with a high disability...
This invention provides a method for treating or for reducing ambulatory deterioration in a human patient diagnosed to be afflicted with relapsing-remitting...
US-9,662,321 Methods for treating newly diagnosed multiple myeloma with ...
Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are...
US-9,662,320 Antagonists of the cannabinoid receptor CB1 for use in the treatment of diseases associated with neuronal...
The invention relates to antagonists of the cannabinoid receptor CBI for use in the treatment and prevention of diseases associated with neural dendritic...
US-9,662,319 Methods and materials for assessing responsiveness to lenalidomide, thalidomide, and/or other thalidomide analogs
This document provides methods and materials related to assessing responsiveness to lenalidomide, thalidomide, and/or other IMiDs (structural and functional...
US-9,662,318 Bitopic muscarinic agonists and antagonists and methods of synthesis and use thereof
Compositions for treating a condition associated with activity of a muscarinic receptor (e.g., one or more of M.sub.1, M.sub.2, M.sub.3, M.sub.4, M.sub.5) and...
US-9,662,317 Methods of administering tolperisone for therapeutic purposes
The present disclosure relates to methods of administering tolperisone to subjects in need thereof. In certain aspects, the present disclosure relates to...
US-9,662,316 Nitrogen-containing heterocyclic compound
The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the...
US-9,662,315 Ameliorating drug-induced elevations in blood pressure by adjunctive use of antihypertensive drugs
Patients which are treated with stimulants (e.g., CNS stimulants, sympathomimetic amine, or anorectic/anorexigenic), such as patients being treated for...
US-9,662,314 Compounds and methods for the treatment of muscular disease, and related screening methods
Disclosed are methods of treating a muscle disease and improving normal muscle function by administering a therapeutically effective amount of an isoprenoid...
US-9,662,313 Compositions and methods for treating amyotrophic lateral sclerosis in responders
A method for treating amyotrophic lateral sclerosis (ALS) in a subject in need thereof comprising administering to said subject an effective amount of...
US-9,662,312 Method for treating glomerulosclerosis
Methods of administering and pharmaceutical compositions of a biphenyl sulfonamide compound which is a dual angiotensin and endothelin receptor antagonist are...
US-9,662,311 Substituted bicyclic compounds as bromodomain inhibitors
The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical...
US-9,662,310 Cyclopropanecarboxylic acid derivative
A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein R.sup.1 represents a C1 to C6 alkyl group...
US-9,662,309 Anti-demodicosis agent
The present invention relates to the use of macrocyclic lactones for treating demodicosis, particularly in dogs.
US-9,662,307 Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or...
US-9,662,306 Compositions and methods for diagnosis and treatment of metabolic syndrome
Compositions including an odd chain fatty acid, and salts and derivatives thereof, and methods for metabolic syndrome treatment and prophylaxis are provided,...
US-9,662,305 Use of bucillamine in the treatment of gout
Disclosed are pharmaceutical compositions comprising, bucillamine, including bucillamine and allopurinol or colchicine, or pharmaceutically acceptable salts or...
US-9,662,304 Substituted glutaurine compounds and substituted glutaurine derivatives
The present invention is directed to compositions and dietary supplements comprising the following compound ##STR00001##
US-9,662,303 Composition and method for treating cancer
The present invention provides a compound for treating cancer including an isolated form of dibenzyl trisulfide (DTS) provided in an effective amount to act as...
US-9,662,302 Hydroxytyrosol and oleuropein compositions for induction of DNA damage, cell death and LSD1 inhibition
Compositions comprising hydroxytyrosol-containing formulations and treatment regiments comprising hydroxytyrosol and/or oleuropein and chemotherapeutic agents...
US-9,662,301 Production of unit dose constructs
Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer...
US-9,662,300 Solid naproxen concentrates and related dosage forms
The invention provides a composition consisting essentially of a solid naproxen concentrate, wherein the solid naproxen concentrate comprises (a) a solid...
US-9,662,299 Yeast cell wall particles for receptor-targeted nanoparticle delivery
The present invention generally relates to yeast cell wall microparticles loaded with nanoparticles for receptor-targeted nanoparticle delivery. In particular,...
US-9,662,298 Wax foamable vehicle and pharmaceutical compositions thereof
Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided....
US-9,662,297 Production of unit dose constructs
Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer...
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