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Patent # Description
US-9,752,219 Self-adaptive, ultra-low elastic modulus shape memory alloys
Methods of manufacturing biocompatible, corrosion resistant, self-adaptive, shape-memory titanium-based alloys by using specific ranges of elements in the...
US-9,752,217 Hot-rolled steel sheet and method of producing the same
In a hot-rolled steel sheet, an average pole density of an orientation group {100}<011> to {223}<110>, which is represented by an arithmetic mean of...
US-9,752,208 Extraction solvent for extracting metallic elements, method for producing same, and method for recovering...
The present invention provides an extraction solvent for extracting metallic elements that is characterized in that: the total concentration of chlorine (Cl2)...
US-9,752,203 Process to improve fatigue strength of micro alloy steels, forged parts made from the process and an apparatus...
The present invention describes a process to make enhanced fatigue strength micro-alloy steel. In the process of the present invention, the soaking temperature...
US-9,752,201 Compositions and method for detecting human parvovirus nucleic acid and for detecting hepatitis A virus nucleic...
Nucleic acid oligomers specific for human parvovirus genomic DNA are disclosed. An assay for amplifying and detecting human parvovirus genotypes 1, 2 and 3...
US-9,752,195 TTC8 as prognostic gene for progressive retinal atrophy in dogs
The invention relates to the use of the TTC8 gene as a biomarker for the prognosis of a canine mammal developing progressive retinal atrophy. The invention also...
US-9,752,194 Methods and compositions useful for diagnosing inflammatory bowel disease-associated neoplasia
The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of microRNAs to diagnose and monitor...
US-9,752,191 Gene expression profiles associated with chronic allograft nephropathy
By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified...
US-9,752,184 Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which...
US-9,752,182 Molecular diagnostics system and methods
The present invention relates to methods for the extraction of nucleic acids from cells, the amplification of segments of nucleic acid and the detection of...
US-9,752,181 System and method for capturing and analyzing cells
A system and method for capturing and analyzing a set of cells, comprising: an array including a set of parallel pores, each pore including a chamber including...
US-9,752,178 Methods for sequencing nucleic acid molecules
Methods and compositions for determining the nucleic acid sequence of polynucleotides that are at least 1500 nucleotides in length are provided.
US-9,752,177 Filtering small nucleic acids using permeabilized cells
Filtering small nucleic acids using permeabilized cells and methods for using the filtering to detect genomic DNA accessibility are described.
US-9,752,176 Methods for preparative in vitro cloning
Methods and devices relate to the isolation of nucleic acids of interest from within a population of nucleic acids such as libraries of nucleic acid sequences.
US-9,752,173 Compositions and methods for inhibiting terminal transferase activity
The present invention realtes to systems and methods for amplifying nucleic acid. In particular, systems and methods are provided for inhibiting polymerase...
US-9,752,172 Methods and kits for sense RNA synthesis
Methods and kits are provided for performing multiple rounds of sense RNA synthesis. The sense RNA molecules can be used in various research and diagnostic...
US-9,752,170 Method of production of monosaccharides
The present invention is directed towards genetic modification of native gene encoding for D-tagatose 3-epimerase and rhamnose isomerase to substantially...
US-9,752,169 Process for the rapid hydrolysis of high solids biomass
The process for the hydrolysis of ligno-cellulosic biomass comprises the steps of A) Contacting a ligno-cellulosic feedstock, the feedstock comprised of biomass...
US-9,752,166 Process and composition for production of organic products
The present invention comprises a process to produce organic products from a single-carbon substrate; microbial compositions used in the process; and a process...
US-9,752,163 Process for the production of isoprenol from mevalonate employing a diphosphomevalonate decarboxylase
Described is a method for the enzymatic production of isoprenol using mevalonate as a substrate and enzymatically converting it by a decarboxylation step into...
US-9,752,161 Methods of producing isoprene and a co-product
The invention features methods producing isoprene and a co-product, such as ethanol, 1,3-propanediol, or hydrogen from cultured cells. The invention also...
US-9,752,160 Use of non-subtype B gag proteins for lentiviral packaging
The invention encompasses a lentiviral packaging vector comprising a non-subtype B gag-pol sequence, particularly a subtype D gag-pol sequence. The invention...
US-9,752,157 High fructan cereal plants
The invention provides cereal plants having a high level of fructan useful for the production of a range of food, beverage, nutraceutical and pharmaceutical...
US-9,752,156 Nucleic acid sequences encoding transcription factors regulating alkaloid biosynthesis and their use in...
Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment, the...
US-9,752,154 High-throughput DNA fragment assembly
This invention is related to methods and systems for vector assembly for transgenic plants. A uniform modular process is used to reduce cycle time and the...
US-9,752,153 Alkynyl-derivatized cap analogs, preparation and uses thereof
Alkynyl-derivatized cap analogs, alkynyl-modified capped RNA, 1,4-disubstituted triazole-derivatized capped RNA, methods of preparation, methods of isolation,...
US-9,752,151 Composition for treatment or metastasis suppression of cancers which includes p34 expression inhibitor or...
The present invention relates to a composition for treatment or metastasis suppression of cancers which includes a p34 expression inhibitor or activity...
US-9,752,149 Matriptase inhibitors and uses thereof against orthomyxoviridae infections
The present invention provides matriptase inhibitors and compositions for treating and preventing orthomyxovirus infections such as flu infections. The present...
US-9,752,147 RNAi-mediated inhibition of connexin 43 for treatment of IOP-related conditions
RNA interference is provided for inhibition of connexin 43 (Cx43) in intraocular pressure-related conditions, including ocular hypertension and glaucoma such as...
US-9,752,146 Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric...
US-9,752,144 Inhibitors of MYH7B and uses thereof
The present invention provides nucleic acid inhibitors of MYH7B and compositions thereof. The present invention also provides methods of treating or preventing...
US-9,752,143 Locked nucleic acid inhibitor of miR-145 and uses thereof
The present invention provides oligonucleotides with chemical motifs that are miR-145 inhibitors. The oligonucleotides can be used for the treatment and...
US-9,752,142 Gapped oligomeric compounds comprising 5'-modified deoxyribonucleosides in the gap and uses thereof
The present invention provides gapped oligomeric compounds comprising at least one 5'-substituted P-D-2'-deoxyribonucleoside in the gap region. Certain such...
US-9,752,141 Microfluidic devices and methods of use in the formation and control of nanoreactors
The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays and combinatorial...
US-9,752,140 Methods and compostions for targeted genomic deletion
Disclosed herein are compositions and methods for generating chromosomal translocations and targeted deletions of specific lengths and at specific locations the...
US-9,752,139 Magnetic three-dimensional cell culture apparatus and method
A culture apparatus and method for growing cells and tissue in a three-dimensional configuration harnesses magnetic, paramagnetic, ferromagnetic and diamagnetic...
US-9,752,138 Methods and apparatuses for isolating and preparing stem cells
The present invention relates to a method of preparing a population of stem cells for autologous implantation to a subject. The cells are activated by...
US-9,752,137 Compounds, compositions and methods for the preparation of peptide/protein conjugates
Compounds, compositions and methods for the preparation of peptide/protein conjugates, said method comprising a step of reacting a compound (2) represented by...
US-9,752,136 Polypeptides having endolysin activity and uses thereof
The present invention relates to novel polypeptides derived from endolysins from a bacteriophage of Clostridium perfringens and to nucleic acid molecules...
US-9,752,135 Thermostable .beta.-glucosidase
A thermostable .beta.-glucosidase including a .beta.-glucosidase catalytic domain, the .beta.-glucosidase catalytic domain including: (A) a polypeptide...
US-9,752,134 Polypeptides having glucoamylase activity and polynucleotides encoding same
The present invention relates to polypeptides having glucoamylase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic...
US-9,752,133 Ref nuclease for site specific Ref-mediated DNA cleavage
Purified Ref polypeptides with increased nuclease site-specific targeting activity, recombinant nucleic acids and cells for expression of such Ref polypeptides,...
US-9,752,132 Engineered CRISPR-CAS9 nucleases with altered PAM specificity
Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting.
US-9,752,131 Multi-domain enzymes having cutinase activity, compositions comprising same and uses thereof
Multi-domain recombinant proteins have a cutinase catalytic domain. The cutinase catalytic domain is a modular domain, which may be combined with other protein...
US-9,752,130 Chalcone synthase dihyrdoflavonol 4-reductase and leucoanthocyanidine reductase from clover, medic ryegrass or...
The present invention relates to nucleic acid fragments encoding amino acid sequences for flavonoid biosynthetic enzymes in plants, and the use thereof for the...
US-9,752,129 Host cell modification with artificial endosymbionts
The present invention is directed generally to host cells with artificial endosymbionts, wherein the artificial endosymbiont and the host cell communicate with...
US-9,752,128 Methods of generating cells exhibiting phenotypic plasticity
The present invention relates to cellular differentiation and, in particular to hybrid cells that exhibit phenotypic plasticity and methods for producing these...
US-9,752,127 Composition for maintaining chromosomal stability of pluripotent stem cells, containing small-molecule compounds
The present invention relates to a composition for maintaining the chromosomal stability of pluripotent stem cells, which contains a small-molecule compound,...
US-9,752,126 Differentiation of human pluripotent stem cells
The present invention provides a method for increasing the expression of MAFA in cells expressing markers characteristic of the pancreatic endocrine lineage...
US-9,752,125 Differentiation of human embryonic stem cells
The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present...
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