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Patent # Description
US-9,751,922 Protein tag, tagged protein, and protein purification method
A technology which enables a high yield and convenient recovery of a protein and also enables a global protein purification is provided. A protein tag...
US-9,751,919 Antimicrobial compositions comprising a hyaluronic acid binding peptide and a .beta.-lactam antibiotic
Compositions and methods for the treatment of antibiotic resistant Staphylococcus aureus infections are provided comprising .beta.-lactam antibiotics, as well...
US-9,751,915 Mutant pores
The invention relates to mutant forms of Msp. The invention also relates to nucleic acid characterization using Msp.
US-9,751,911 Solomonamide analogue compounds, pharmaceuticals containing solomonamide analogue compounds, and processes for...
Solomanamide analogs of Formula-I having anti-inflammatory activity, and viable synthetic routes for the preparation of such analogs, including the synthesis of...
US-9,751,909 Synthesis and uses of nucleic acid compounds with conformationally restricted monomers
Processes for synthesis of conformationally restricted nucleomonomers (CRN) by ozonolysis or oxidation of a 2'-vinyl substituted nucleoside precursor with...
US-9,751,902 Organic titanium derivative and process for the preparation thereof, ink containing the derivative and ceramic...
Described is a production process for the preparation of an organic titanium derivative useful for the preparation of yellow inks for digital printing on...
US-9,751,899 Synthesis method of alkoxysilanes
The direct depolymerization of biogenic and other high surface area silica sources uses both simple and hindered diols to produce alkoxysilanes in one or two...
US-9,751,894 Cephem compounds, their production and use
Cephem compounds, pharmaceutically acceptable salts thereof, and methods of using same, wherein the compound has a bicyclic nitrogen-containing aromatic...
US-9,751,893 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
The present invention provides methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds, as well as methods of treating,...
US-9,751,888 Heterocyclic compounds and uses thereof
Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods...
US-9,751,886 4-amino-6-phenyl-6,7-dihydro[1,2,3]triazolo[1,5-A]pyrazine derivatives as inhibitors of beta-secretase (BACE)
The present invention relates to novel 6,7-dihydro[1,2,3]triazolo[1,5-a]pyrazin-6-yl derivatives as inhibitors of beta-secretase, also known as beta-site...
US-9,751,884 N-aryl unsaturated fused ring tertiary amine compounds, preparation method and anti-tumor applications thereof
The present invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, its preparation method, a pharmaceutical composition...
US-9,751,883 Preparation of certain [((6BR,10AS)-2,3,6B,7,8,9,10, 10A-octahydro-1H-pyrido[3',4':4,5]pyrrolo...
The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines of Formula 2J, as shown below, intermediates useful...
US-9,751,879 Tricyclic compounds as anticancer agents
The present invention is directed to tricyclic compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using...
US-9,751,878 Tetrahydronaphthyridine somatostatin receptor 5 antagonists
A compound having an SSTR5 antagonist action and use of the compound as a medicament are provided. Specifically, a compound represented by the following...
US-9,751,877 Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I ##STR00001## as defined...
US-9,751,876 Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
Bicyclic heterocyclic derivatives of formula I useful in inhibiting PDGF receptor mediated biological activity. ##STR00001## wherein A is ##STR00002## and...
US-9,751,875 Quinine compounds, and optical isomers, preparation method and medical use thereof
The present invention discloses a class of quinine compounds and pharmaceutically acceptable salts, solvates, prodrugs or optical isomers thereof. Also...
US-9,751,874 Hydroxy containing FXR (NR1H4) modulating compounds
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the...
US-9,751,873 Aryl sultam derivatives as RORc modulators
Compounds of the formula I: ##STR00001## or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X.sup.1, X.sup.2, X.sup.3, X.sup.4, Y, Z,...
US-9,751,872 Coloring compound and toner
This invention aims at providing a compound capable of providing a toner having high covering power and a toner having high covering power, which is achieved by...
US-9,751,871 Bis(difluoromethyl)pyrazoles as fungicides
Bis(difluoromethyl)pyrazole derivatives of the formula (I) ##STR00001## in which the symbols R.sup.1, X and G are each as defined in the description, and...
US-9,751,870 Oxytocin receptor agonists for the treatment of CNS diseases
The invention relates to the use of a compound of formula I ##STR00001## wherein A.sup.1 is phenyl or a five or six membered hereroaryl group, containing 1, 2...
US-9,751,869 LXR modulators
The present invention provides compounds of Formula I and Formula II: or pharmaceutically acceptable salts or solvates thereof, as modulators of liver X...
US-9,751,868 Benzocyanine compounds
Compounds useful as labels with properties comparable to known fluorescent compounds. The compounds are conjugated to proteins and nucleic acids for biological...
US-9,751,867 Plant growth regulating compounds
The present invention relates to novel heterocyclic derivatives of Formula (I), to processes and intermediates for preparing them, to plant growth regulator and...
US-9,751,866 Hemi-aminal ethers and thioethers of N-alkenyl cyclic compounds
Described herein are hemi-aminal ethers and thioethers of N-alkenyl cyclic compounds that may be produced through a reaction comprising: (A) at least one first...
US-9,751,865 Dihydro-hydantoin derivatives with herbicidal activity
The invention relates to substituted dihydro-hydantoin derivatives of the formula (I) wherein X, R.sup.a, R.sup.b, R.sup.c, R.sup.1, R.sup.2 and R.sup.3 are as...
US-9,751,864 Methods for preparing triazole agonists of the APJ receptor
Methods of preparing compounds of Formula VI, salts thereof, tautomers thereof, or salts of the tautomers include cyclizing compounds of Formula V, salts...
US-9,751,863 Therapeutically active compounds and their methods of use
Provided are compounds useful for treating cancer and methods of making the compounds and intermediates described herein.
US-9,751,862 Pesticidally active substituted pyridyl carboxamides
Compounds of formula (I) wherein m is 0 or 1; Z is methine or nitrogen; X is oxygen or sulfur, R.sub.1 is C.sub.1-C.sub.6-alkyl, halo-C.sub.1-C.sub.6-alkyl,...
US-9,751,861 N1-(3,3,3-trifluoro-2-hydroxo-2-methylpropionyl)-piperidine derivatives as inhibitors of pyruvate dehydrogenase...
Compounds of the formula (I) in which R, R.sup.1 and R.sup.3 have the meanings indicated in claim 1, are inhibitors of pyruvate dehydrogenase kinase (PDHK), and...
US-9,751,860 Piperidin-4YL-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists
The present invention relates to compounds that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical...
US-9,751,859 Process for preparing an anti-cancer agent, ...
The present invention relates a new process to synthesize 1-((4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)meth- yl)cyclopropanamine...
US-9,751,858 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals
The present invention relates to compounds of the formula I, ##STR00001## wherein Ht, G, R.sup.10, R.sup.30, R.sup.40, R.sup.50 and R.sup.60 have the meanings...
US-9,751,852 Sulfoxide compound and method of producing benzothiophene derivatives using the same
A sulfoxide compound and method of producing benzothiophene derivatives using the same are provided. The sulfoxide compound is represented by formula (I),...
US-9,751,848 Chelate-controlled diastereoselective hydrogenation with heterogeneous catalyst
A catalyst, method of using, and use of a hydrogenation catalyst, preferably palladium on a support, preferably alumina or activated charcoal support. This in...
US-9,751,833 Antimicrobial biguanide metal complexes
A compound comprising a metal species and a biologically acceptable ligand, wherein the biologically acceptable ligand comprises a biguanide moiety, and wherein...
US-9,751,822 Method for producing unsaturated carboxylic acid and supported catalyst
The present invention relates to a method for producing an unsaturated carboxylic acid using a catalyst having both a high catalytic performance and a high...
US-9,751,820 Purification of isoprene from renewable resources
Methods and apparatus for the purification of isoprene, such as the purification of a bioisoprene composition from fermentor off-gas. The apparatus includes two...
US-9,751,817 Combined reactor effluent and regenerant recirculation for detergent alkylation process
A process for producing alkylaromatic compounds is described. The process involves utilizing at least a portion of the aromatic compound used to regenerate the...
US-9,751,805 Method for stabilizing beta-hemihydrate plaster
The instant invention is concerned with the post-treatment of .beta.-hemihydrate plasters for the purpose of stabilization. The invention relies in the addition...
US-9,751,800 Heat treatable coated article with tungsten-doped zirconium based layer(s) in coating
In certain example embodiments, a coated article includes a tungsten-doped zirconium based layer before heat treatment (HT). The coated article is heat treated...
US-9,751,798 White, opaque,.beta.-spodumene glass-ceramic articles with inherent damage resistance and methods for making...
Crystallizable glasses, glass-ceramics, IXable glass-ceramics, and IX glass-ceramics are disclosed. The glass-ceramics exhibit .beta.-spodumene ss as the...
US-9,751,793 Method of manufacturing glass molded product and lower die for molding glass
A method of manufacturing a glass molded product includes the steps of preparing a lower die including a lower die surface and a space forming surface formed to...
US-9,751,753 Integration of active devices with passive components and MEMS devices
Integration of active devices with passive components and MEMS devices is disclosed. An integrated semiconductor structure includes an active device having a...
US-9,751,741 Dispensing apparatus, method of dispensing, capping apparatus and method of capping
A dispensing apparatus including a holding portion for holding a plurality of caps; a retaining device including a gap expandable between a retaining...
US-9,751,735 Fluidically actuatable failsafe disk brake system and lifting device comprising said system
A fluidically actuatable disk brake system includes brake cylinder pairs each including brake cylinders arranged on both sides of a brake disk in at least one...
US-9,751,717 Package with high young's modulus yarn and method for winding the yarn package
The invention concerns an improved yarn package and a method winding a package of high Young's modulus yarn. The package has a low normalized standard deviation...
US-9,751,708 Sheet transport device and image forming apparatus
A sheet transport device includes a transport path along which a sheet is transported in one direction, the sheet being transported with a corner at a leading...
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