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Patent # Description
US-9,757,456 Super-saturating delivery vehicles for poorly water-soluble pharmaceutical and cosmetic active ingredients and...
A pharmaceutical or cosmetic composition, comprising a substantially poorly water-soluble pharmaceutical active ingredient; and a nanoporous folic acid...
US-9,757,455 Oral therapeutic compound delivery system
The present invention provides an oral delivery system for a therapeutic compound that is an acid, a salt of an acid or an unionized compound or a proactive...
US-9,757,454 Stable aqueous formulations of adalimumab
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
US-9,757,453 Nanoparticle complexes of anti-CD20 antibodies, albumin and paclitaxel
Described are stable nanoparticle complexes of 100 nm to 900 nm comprising paclitaxel, albumin and a polypeptide which binds CD20 (such as rituximab). The...
US-9,757,452 Methods of treatment of keloid using an anti-VEGF agent
Methods for treating pterygium recurrence following pterygiectomy, and for treating keloid recurrence, following surgical removal of the keloid, are disclosed....
US-9,757,451 Use of RANK/RANKL antagonists for treating muscular dystrophy
The present invention relates to uses and methods comprising one or more RANK/RANKL antagonists or of a pharmaceutical composition comprising one or more...
US-9,757,450 Fusion protein comprising diphtheria toxin non-toxic mutant CRM197 or fragment thereof
Provided in the present invention are a diphtheria toxin non-toxic mutant CRM197 or a fragment thereof as an adjuvant in a fusion protein and the use thereof to...
US-9,757,449 Acceleration of vector virus induced immune response in avians
The addition of an oligodeoxynucleotide that is an avian TLR21 agonist, to an avian Herpesvirus vector vaccine, provides an acceleration of the immune response...
US-9,757,448 Methods of treating cerebral amyloid angiopathy
Methods for treating and reducing risk of cerebral amyloid angiopathy (CAA) using nasal vaccination with a proteosome adjuvant.
US-9,757,447 Recombinantly produced allergens
Methods for producing an allergen composition, methods for in vitro diagnosis of type I allergy, and diagnostic kits for performing diagnosis employ Bos d 23k...
US-9,757,446 Influenza virus vectors and uses therefor
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein...
US-9,757,445 Attenuated Pasteurella multocida vaccines and methods of making and use thereof
The present invention provides attenuated P. multocida strains that elicit an immune response in animal P. multocida, compositions comprising said strains,...
US-9,757,444 Immunogenic compositions for the prevention and treatment of meningococcal disease
The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared...
US-9,757,443 Non-lipidated variants of Neisseria meningitidis ORF2086 antigens
The present invention relates to compositions including an isolated non-pyruvylated non-lipidated ORF2086 polypeptide, and methods thereof. In an exemplary...
US-9,757,442 Inactivated bacterial cell formulation
The invention relates to the use of lactic acid-producing bacteria to boost the immune system.
US-9,757,441 Anti-Mycoplasma spp. subunit vaccine
Provided in the present invention are anti-Mycoplasma spp. subunit vaccines, especially proteins suitable for being used as the active ingredient of the...
US-9,757,440 Method for treating cancer with Toxoplasma gondii vaccine
The present invention provides attenuated Toxoplasma gondii mutants for use as vaccines in the prevention or treatment of cancer.
US-9,757,439 Peptide vaccine comprising mutant RAS peptide and chemotherapeutic agent
There is disclosed at least one peptide suitable for eliciting an immune response, for use in the treatment of cancer. The, or each, peptide corresponds to a...
US-9,757,438 Mucin antigen vaccine
Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the...
US-9,757,437 Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an ...
US-9,757,436 Antimicrobial composition comprising pyrogenic silica and serrathiopeptidase and uses thereof
Methods are provided for treatment of wounds using a complex antimicrobial sorption composition possessing the necrolytic effect for treating the purulent...
US-9,757,435 Clostridium histolyticum enzymes and methods for the use thereof
The invention relates to recombinant nucleic acid and polypeptides encoding collagenase I and collagenase II, methods for the preparation thereof and methods...
US-9,757,434 FXa variant compositions
Compositions are provided comprising recombinant variants of the human clotting Factor Xa. Such compositions include a wide variety of isoforms and...
US-9,757,433 Modified ACE2 polypeptides
The present invention relates to modified angiotensin converting enzyme 2 (ACE2) polypeptides and pharmaceutical and analytical uses thereof. In particular, the...
US-9,757,432 Materials and methods useful for treating glioblastorna
The present invention provides compositions and methods useful for treating cancers such as glioblastoma. SapC-DOPS was found to be synergistically effective at...
US-9,757,431 Methods and compositions for the induction of hypothermia
Provided herein are methods for the induction of hypothermia and the treatment of clinical insults in a subject through the administration of a regulated...
US-9,757,430 Bioactive compositions derivable from platelet concentrates, and methods for preparing and using same
The present disclosure provides a composition comprising a bioactive fraction derived from a platelet concentrate, methods of making the bioactive fraction, and...
US-9,757,429 Methods for detecting cardiac damage
The present invention relates to a method for detecting heart damage in a patient. The invention also relates to methods for treatment of patients identified as...
US-9,757,428 Designed peptides for tight junction barrier modulation
According to aspects illustrated herein, there is provided an agent that transiently disrupts claudin-1 within tight junctions. The agent includes a peptide...
US-9,757,427 Combination comprising zidovudine and polymyxin
The present invention relates to the use of a combination of an anti-retroviral agent such as zidovudine and an anti-microbial agent for killing clinically...
US-9,757,426 Peptide additives for enhancing acceptance and ingestion of edibles by rodents and uses thereof
Methods of using of guanylin family peptides to induce food or odor preferences in mammals are provided, along with methods for inducing feeding responses in...
US-9,757,425 Method and composition for synchronizing time of insemination
Methods and compositions for synchronizing the time of insemination in swine are described. More particularly, methods are described for synchronizing the time...
US-9,757,424 Compositions and methods of treating gliomas
The present invention provides, inter alia, methods for treating or ameliorating the effects of a glioma. Methods of this invention include administering to a...
US-9,757,423 Composition to enhance HDL cholesterol and to decrease intima-media thickening in animals and humans and a...
A method of producing a product to correct hypercholesterolemia including pulping fruits of Emblica officinalis with demineralized water to create a slurry. The...
US-9,757,422 Methods and compositions for regenerating and repairing damaged or aged tissue or organs using nonviable...
Compositions and methods are provided herein for regenerating and repairing damaged or aged tissue or organs using nonviable lethally irradiated or lyophilized...
US-9,757,421 Adipose tissue-derived stem cells for veterinary use
The invention provides for compositions and methods for making and using adipose-derived stem cells for treating non-human mammals for various medical conditions.
US-9,757,420 Gene editing for HIV gene therapy
The present disclosure is in the field of genome engineering, particularly targeted integration of anti-HIV transgenes into the genome of a cell for the...
US-9,757,419 Skeletal muscle regeneration using mesenchymal system cells
The present invention relates to a therapeutic substance and/or medicament and methods relating to the use of said substance and/or medicament for skeletal...
US-9,757,418 Process for removing growth factors from platelets
In vitro and in vivo application of sub-atmospheric, negative pressure on growth factor starting material, such as whole blood, extracts growth factors from the...
US-9,757,417 Bioactive glass preparation and use
A process of preparing a glass comprising: (a) heating a mixture of precursor chemicals to a melt temperature to form a melt, the melt being characterized in...
US-9,757,416 Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same
The present invention discloses pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which...
US-9,757,415 Composition comprising solanum glaucophyllum for preventing and/or treating hypocalcaemia and for stabilizing...
The present invention provides a pharmaceutical and/or veterinary composition comprising a retard release formulation of a Solarium glaucophyllum preparation....
US-9,757,414 Magnesium compositions and uses thereof for neurological disorders
A composition for administration to a subject, such as oral administration to a subject, for example, has been provided. Such a composition may comprise at...
US-9,757,413 Weight reducing composition
The invention relates to soft drink industry, in particular, to dietetic nutrition. The inventive weight reducing composition comprises 0.01-10 mg/l of sodium...
US-9,757,412 Ferrate and povidone iodine (PI) composition
A composition and method useful in promoting hemostasis, absorbing ooze, and being antimicrobial with respect to an open wound. The composition broadly includes...
US-9,757,411 Poloxamer therapy for heart failure
Provided methods of administering poloxamer 188 for treating heart failure by only a single short relatively high dose infusion, or by regimen that includes the...
US-9,757,409 Method to prepare ganoderma lucidum polysaccharides possessing insulin-sensitizing properties and applications...
The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides can reduce hyperglycemia and improve...
US-9,757,408 Therapeutic agent for inflammatory diseases, containing adenosine N1-oxide as an effective ingredient
The present invention has an object to provide an effective and safe therapeutic agent for inflammatory diseases such as sepsis, hepatitis, and inflammatory...
US-9,757,407 Treatment of viral infections by modulation of host cell metabolic pathways
Alterations of certain metabolite concentrations and fluxes that occur in response to viral infection are described. Host cell enzymes in the involved metabolic...
US-9,757,406 Combination formulation of two antiviral compounds
Disclosed are pharmaceutical compositions comprising Compound I, having the formula: ##STR00001## and an effective amount of sofosbuvir wherein the sofosbuvir...
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